Oral dispersible tablets

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Oral dispersible tablets”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Drug:
Drug refers to any substance that is used to diagnose, cure, mitigate, treat, or prevent diseases. In pharmacology, it often denotes active pharmaceutical ingredients (APIs) that are formulated into dosage forms like tablets or capsules. In the context of orally disintegrating tablets (ODTs), drug release and bioavailability are critical factors influencing therapeutic efficacy.

2) Water:
Water is essential in many pharmaceutical formulations, including orally disintegrating tablets. It acts as a solvent, solvent in preparing drugs and excipients, and is crucial for dissolution and disintegration processes. The amount of water required for the optimal function of ODTs is carefully controlled to ensure they dissolve effectively when ingested.

3) Camphor:
Camphor is a volatile material often used in the preparation of sublimation tablets, contributing to their high porosity. Its ability to evaporate leaves behind pores that facilitate rapid dissolution and disintegration. In the context of ODTs, camphor also assists in masking the bitter taste of certain drugs.

4) Powder:
Powder in pharmaceutical terminology refers to the finely ground solid particles of drugs and excipients. The properties of the powder, including flowability and compressibility, significantly impact the manufacturing processes for tablets. The formulation involving powders dictates the efficiency of disintegration and drug release characteristics in ODTs.

5) Bitter:
Bitter refers to an unpleasant taste often associated with certain medicines, which can deter patient compliance. Effective taste masking techniques are crucial in the formulation of ODTs. Aimed at enhancing patient experience and adherence to medication regimens, the development of formulations that minimize bitterness is central to ODT research.

6) Surface:
Surface refers to the outer layer of a tablet, which plays a significant role in disintegration and drug release. The microstructural properties of the surface can impact the rate at which water interacts with the tablet, facilitating dissolution. Surface characteristics can also influence taste perception, critical for patient acceptance.

7) Swallowing:
Swallowing is the act of passing the dosage form through the esophagus and into the stomach. Certain patient populations, like the elderly or pediatrics, may find it difficult to swallow traditional tablets. ODTs provide an alternative, as they dissolve or disintegrate in the mouth, eliminating the need for swallowing.

8) Substance:
Substance refers to any form of matter with uniform properties, often referring to active ingredients or excipients in pharmaceutical contexts. In the development of ODTs, understanding the properties of each substance used in formulations is critical for achieving desired characteristics like solubility, stability, and bioavailability.

9) Medium:
Medium, often used to describe a solvent or carrier in pharmaceutical contexts, plays a crucial role in dissolution and absorption processes. For ODTs, the choice of medium can affect how well the drugs dissolve and how quickly they are available for absorption, thus directly impacting efficacy.

10) Sugar:
Sugar plays a structural and functional role in pharmaceutical formulations, especially in taste masking and improving mouthfeel. In ODTs, water-soluble sugars can improve the dissolution profile and enhance the overall palatability of the tablets. Balancing taste while ensuring effective drug delivery is key in ODT design.

11) Study (Studying):
Study in pharmaceutical contexts implies systematic research efforts aimed at understanding various aspects of drug formulation, delivery, and efficacy. It encompasses the developmental processes for ODTs, including evaluating their disintegration times, dissolution rates, and stability, as well as ongoing assessments for optimization.

12) Swelling:
Swelling refers to the increase in volume of a material when in contact with a liquid, such as during the disintegration of ODTs. Superdisintegrants employed in ODT formulations operate through swelling mechanisms to facilitate quicker breakdown of the tablets, enhancing drug release characteristics.

13) Kumar:
Kumar is a common surname and can refer to researchers and authors involved in the development of ODTs. Their contributions in formulating and evaluating various aspects of drug delivery systems, demonstrated through research articles, help advance the knowledge base in the pharmaceutical field.

14) Soil:
Soil in a broader context represents a medium for plant growth and is typically not associated with pharmaceutical studies directly. However, its mention might refer metaphorically to foundations or underlying principles, much like the foundational scientific studies that underpin drug formulation and delivery systems.

15) Pur:
Poor is often used to describe inadequate performance or low solubility in pharmaceutical contexts. When referring to drug solubility, it underscores the importance of formulating techniques, like ODTs, aimed at enhancing the bioavailability of drugs which inherently have poor dissolution characteristics.

16) Subramanyam:
Subramanyam is likely a reference to a researcher or author whose work has contributed to the field of pharmaceutical sciences, particularly in the characterization and evaluation of drug formulations. Such names are often cited in literature to acknowledge contributions to specific studies or findings.

17) Performance:
Performance refers to how well a drug formulation achieves intended therapeutic outcomes, including dissolution rate, bioavailability, and patient compliance. For ODTs, performance metrics involve measuring disintegration time and drug release profiles and ensuring that these meet regulatory requirements and patient needs.

18) Container:
Container in pharmaceutical contexts refers to packaging that holds the dosage form, ensuring its integrity and stability during storage and transport. The choice of container is vital for ODTs, as they are sensitive to environmental conditions, requiring packaging that maintains their quality and effectiveness.

19) Swallowed:
Swallowed involves the act of ingesting a dosage form, which, in the case of conventional tablets, requires adequate water. ODTs are designed for disintegration in the mouth, eliminating the need for swallowing, which makes them suitable for patients with difficulties in ingesting solid forms.

20) Composite:
Composite refers to a combination of two or more substances to achieve desired properties. In the context of ODTs, composites can be used to enhance taste masking or improve tablet disintegration. The formulation of a composite tablet can optimize performance characteristics and patient compliance.

21) Medicine:
Medicine refers to substances used for treating diseases and improving health. In the field of pharmaceuticals, medicines can be formulated into various delivery systems, including ODTs, which aim to enhance patient compliance and therapeutic effectiveness by providing rapid dissolution and absorption.

22) Relative:
Relative refers to a comparison between two or more entities or performance metrics. In pharmaceuticals, relative efficacy is often assessed to understand how a new formulation like an ODT performs compared to traditional dosage forms in terms of bioavailability, patient acceptance, and therapeutic outcomes.

23) Quality:
Quality in pharmaceuticals signifies the degree to which a product meets predetermined standards and specifications. The quality of ODTs is assessed through rigorous testing methods to ensure that they dissolve appropriately, deliver the correct dose, and are stable over time, hence reinforcing patient trust.

24) Pouring:
Pouring refers to the action of transferring a liquid from one container to another, often used in the preparation processes of pharmaceutical formulations. In ODT production, pouring might be relevant in the context of preparing suspensions or solutions during the manufacturing of tablet components.

25) Gelatin:
Gelatin is a biopolymer often used in pharmaceutical formulations for its gelling properties. It can serve as a binder or a delivery matrix in ODTs, providing structuring capabilities while maintaining desirable disintegrating properties that facilitate rapid dissolution and release of the active drug.

26) Patil:
Patil is likely a reference to an author or researcher whose work contributes to the formulation and evaluation of pharmaceuticals. The acknowledgment of such individuals in published studies highlights the collaborative nature of research, where many experts contribute their knowledge to advance the field.

27) Table:
Table generally refers to the presentation of data or results in a structured format. In pharmaceutical literature, tables are critical for summarizing experimental results and comparisons, such as dissolution rates, disintegration times, and other critical metrics related to the performance of ODT formulations.

28) Hari (Harin):
Hari is possibly a reference to a researcher or academic who has made contributions to the field of pharmaceutical sciences. Recognition of such individuals is essential in scientific literature to give credit for ideas, methodologies, and findings that advance knowledge in the discipline.

29) Beta:
Beta is often used in pharmacology to denote a type of cyclodextrin that can enhance the solubility of poorly soluble drugs through complexation. For ODT formulations, this capability can significantly improve the therapeutic performance of active ingredients that otherwise have limited bioavailability.

30) Gold (Golden):
Gold, in a metaphorical sense, may represent the gold standard or best practice in manufacturing, formulation, or therapeutic efficacy within pharmaceuticals. The aspiration in formulating ODTs is to achieve a product that sets a benchmark for efficacy, patient compliance, and overall quality.

31) Post:
Post typically refers to the phase or position after a specified event, such as post-manufacturing evaluation of ODTs. This phrase may relate to the procedures and steps taken once tablets are produced, ensuring they meet standards for quality, stability, and performance before distribution.