UV-Vis study of phytoconstituents in Amalakyadi Gana formulation.

| Posted in: Scientific

Journal name: World Journal of Pharmaceutical Research
Original article title: Uv – vis. spectroscopic study on phytoconstituents of amalakyadi gana (compound formulation)
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
This page presents a generated summary with additional references; See source (below) for actual content.

Summary of article contents:

Introduction

The study presented in the World Journal of Pharmaceutical Research focuses on the investigation of phyto-constituents in the compound formulation known as Amalakyadi Gana. This formulation, referenced in Ayurvedic texts, is utilized for its medicinal properties, particularly in treating various kinds of fevers. Comprising four primary components—Amalaki, Haritaki, Pippali, and Citraka—this formulation is characterized primarily through the application of UV-Vis spectroscopy. This analytical technique serves as a vital tool in identifying and characterizing the biomolecules present in medicinal plants, thus facilitating their authentication and potential adulteration detection.

Identification of Phyto-Constituents through UV-Vis Spectroscopy

One of the central concepts discussed in the study is the use of UV-Vis spectroscopy to identify specific phyto-constituents within the 50% Hydroalcohalic extract of Amalakyadi Gana. The UV-Vis profile revealed significant absorption peaks at 213 nm and 267 nm, indicating the presence of important compounds such as tannins and flavonoids. These compounds are well-known in plant-based medicines for their therapeutic properties and play a crucial role in the efficacy of herbal formulations. The study emphasizes the spectral characteristics associated with phytochemicals, which aid in their identification and characterization.

Therapeutic Potential of Tannins

Another important concept highlighted in the study is the therapeutic potential of tannins. The presence of tannins, which fall within the range of 230-290 nm in UV-Vis spectra, suggests their significance in the formulation of Amalakyadi Gana. Tannins are recognized for their potential as free radical scavengers, thereby conferring protective properties against chronic diseases, including cancer. The study underscores that plants containing tannins are traditionally utilized in phytomedicine to treat various ailments, showcasing their relevance in modern herbal remedies.

Biological Activities of Flavonoids

The study also draws attention to the presence of flavonoids within the extract. Flavonoids, which can exist in multiple forms such as isoflavones and flavonols, exhibit a plethora of biological activities, including antioxidant, anti-inflammatory, anti-microbial, and anti-cancer properties. Their identification in the Amalakyadi Gana formulation accentuates the health benefits associated with its usage. The study articulates the necessity of phenolic compounds in enhancing the therapeutic profile of herbal formulations, further establishing their importance in Ayurvedic medicine.

Conclusion

In summary, the research conducted on the UV-Vis spectroscopic analysis of Amalakyadi Gana provides compelling evidence of the presence of critical phyto-constituents, particularly tannins and flavonoids, which contribute to its medicinal efficacy. These findings advocate for the therapeutic application of Amalakyadi Gana in treating chronic and intestinal disorders, while also positioning it as a potential agent for cancer prevention due to its antioxidant properties. The study underscores the relevance of modern analytical techniques in validating traditional medicinal knowledge and encourages further exploration into the therapeutic potentials encapsulated within Ayurvedic formulations.

Original source:

This page is merely a summary which is automatically generated hence you should visit the source to read the original article which includes the author, publication date, notes and references.

Author:

Sadhana Singh, Brijesh Singh, Rashmi Yadav and Vinod Kumar Joshi


World Journal of Pharmaceutical Research:

(An ISO 9001:2015 Certified International Journal)

Full text available for: Uv – vis. spectroscopic study on phytoconstituents of amalakyadi gana (compound formulation)

Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research

Doi: 10.20959/wjpr201710-9336


Download the PDF file of the original publication


FAQ section (important questions/answers):

What is the focus of the UV-Vis spectroscopic study?

The study focuses on understanding the UV-Vis characteristics of Amalakyadi Gana to identify and characterize its phyto-constituents using spectroscopic methods.

Which plants are included in the Amalakyadi Gana formulation?

Amalakyadi Gana consists of four medicinal plants: Amalaki, Haritaki, Pippali, and Citraka, known for their health benefits in Ayurvedic medicine.

What spectroscopy technique was used for the study?

The study utilized ultraviolet-visible (UV-Vis) spectroscopy to analyze the 50% hydroalcoholic extract of Amalakyadi Gana for its phytochemical constituents.

What phyto-constituents were identified in the study?

The UV-Vis spectrum revealed the presence of tannins and flavonoids, which are important for their therapeutic properties in treating chronic diseases.

How were the plant samples prepared for analysis?

Plant samples were coarsely powdered, extracted using a Soxhlet apparatus, and filtered to obtain a concentrated hydroalcoholic extract for UV-Vis analysis.

Why are tannins and flavonoids significant in this research?

Tannins and flavonoids have various biological activities such as antioxidant and anti-inflammatory effects, making them valuable for medical applications in chronic and intestinal disorders.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “UV-Vis study of phytoconstituents in Amalakyadi Gana formulation.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Gana:
In Ayurveda, 'Gana' refers to a group or category of medicinal herbs that are combined for therapeutic purposes. The concept emphasizes the synergistic effects of multiple herbs working together, enhancing their properties in treating ailments more effectively than single herbs alone, as seen in formulations like Amalakyadi Gana.

2) Amalakyadi (Amalaki-adi):
The term 'Amalakyadi' pertains to a specific compound formulation in Ayurveda, which consists of several medicinal plants, including Amalaki. It highlights the traditional use of a combination that is believed to have potent health benefits, particularly for conditions like fever and digestive disorders, through collaborative healing properties.

3) Haritaki:
Haritaki, or 'Terminalia chebula', is a prominent herb in Ayurveda known for its various health benefits. It is celebrated for its efficacy in digestion, detoxification, and its ability to balance the three doshas. Additionally, it is considered a powerful rejuvenator and is often used in formulations for overall wellness.

4) Amalaki:
Amalaki, or 'Emblica officinalis', is a cornerstone herb in Ayurvedic medicine, recognized for its high vitamin C content and antioxidant properties. It is revered for promoting digestion, enhancing immunity, and as a rejuvenating tonic, making it essential in many Ayurvedic formulations intended for health maintenance and disease prevention.

5) Pippali (Pippalin):
Pippali, or 'Piper longum', is a key spice and medicinal herb used in Ayurveda to enhance digestion, respiratory function, and metabolic processes. Known for its warming and enhancing effects, it is often included in herbal formulations aimed at improving bioavailability and efficacy of other herbs when consumed.

6) Citraka:
Citraka, or 'Plumbago zeylanica', is an important plant in Ayurveda, valued for its ability to stimulate digestion and metabolism. It is reputed for its cleansing properties and is often included in formulations for digestive disorders. Its therapeutic effects make it integral to many Ayurvedic treatments for health optimization.

7) Flavonoid:
Flavonoids are a class of phytonutrients found in various plants, noted for their antioxidant properties. In the context of Ayurvedic formulations, they play a crucial role in enhancing health benefits, as they contribute to anti-inflammatory, anti-cancer, and cardioprotective effects. Their presence in herbal extracts is often analyzed using UV-Vis spectroscopy.

8) Disease:
In Ayurveda, 'disease' refers to imbalances in the body's constitution (doshas) that lead to various health issues. Understanding the nature of disease is vital for diagnosis and treatment. Ayurvedic medicine aims at restoring balance through herbal formulations, lifestyle changes, and dietary adjustments to promote holistic health.

9) Drug:
The term 'drug' in the context of Ayurveda encompasses herbal formulations and preparations that are used for therapeutic purposes. Ayurvedic drugs often comprise various plant constituents, aimed at correcting doshic imbalances and promoting health. Their efficacy is often researched using advanced methods like spectroscopy to analyze active components.

10) Dravyaguna (Dravya-guna):
Dravyaguna is a branch of Ayurveda focused on the study of herbal drugs and their properties. It involves understanding medicinal plants, their active constituents, and their therapeutic applications in health improvement. Profound knowledge of dravyaguna underpins the effective formulation and use of Ayurvedic medications in practice.

11) Ayurveda (Ayus-veda):
Ayurveda is a traditional system of medicine from India, emphasizing balance in the body's systems through diet, herbal treatment, and yogic practices. It seeks to maintain health and treat diseases by understanding the individual's constitution and the principles of natural elements, aiming for holistic wellness and prevention.

12) Varanasi (Varanashi):
Varanasi is a historic city in India, known as a center of learning and spirituality. It is significant in Ayurvedic education and practice, hosting institutions that study traditional medicine. The city's cultural importance makes it a vital location for research and practice of Ayurvedic principles and methodologies.

13) India:
India is the birthplace of Ayurveda, a holistic healing system that has been practiced for thousands of years. Its rich biodiversity provides a plethora of medicinal plants that form the foundation of Ayurvedic treatments. Indian culture places a strong emphasis on health, wellness, and the interconnectedness of all life.

14) Emblica officinalis:
Emblica officinalis, commonly known as Amalaki, is a revered plant in Ayurveda. It is known for its high vitamin C content and powerful antioxidant properties. Used in various formulations, it supports digestion, boosts immunity, and provides rejuvenation, making it a staple in Ayurvedic medicine for overall health.

15) Terminalia chebula:
Terminalia chebula, or Haritaki, is known as a potent herb in Ayurveda. It is often referred to as the 'king of herbs' for its numerous health benefits, including digestion support and detoxification. Its applications extend to promoting overall vitality and wellness in diverse Ayurvedic formulations.

16) Piper longum:
Piper longum, or Pippali, is a significant herb used in Ayurveda known for enhancing respiratory function and digestion. It is considered a vital ingredient in many herbal combinations due to its ability to potentiate the effects of other herbs and improve their absorption in the body.

17) Shalyatantra (Salyatantra, Shalya-tantra, Shalyatamtra):
Shalya-tantra is a branch of Ayurveda that deals with surgical techniques and the treatment of injuries, wounds, and fractures. It encompasses traditional surgical practices focused on patient safety and the healing process, demonstrating Ayurveda's holistic approach, merging both medicinal and procedural treatments in healthcare.

18) Bilaspur:
Bilaspur is a city in India that houses Ayurvedic institutions, contributing to the study and practice of traditional medicine. Its significance lies in providing educational opportunities and facilities for research in Ayurvedic treatments, enhancing the understanding and application of herbal medicine in the region.

19) Tantra (Tamtra, Tantrism):
In Ayurveda, 'tantra' refers to a systematic study or technique, often guiding the practice of rituals and healing methods. It encompasses various disciplines, including pharmacognosy and surgical techniques, that form the backbone of Ayurvedic practices, emphasizing comprehensive approaches to health and wellness.

20) Shalya (Salya):
Shalya refers to the surgical aspect of Ayurveda, which focuses on treatment methodologies for physical ailments requiring intervention. It emphasizes careful assessment and traditional techniques, blending surgical practices with herbal treatment to provide a holistic approach to health, recovery, and patient care.

21) Cancer:
Cancer is recognized as a debilitating disease characterized by the uncontrolled growth of abnormal cells. In Ayurveda, treatments often target the root causes, focusing on dietary, lifestyle, and herbal approaches to support strength and vitality. Research into Ayurvedic herbs for cancer support is ongoing and significant.

22) Joshi (Josi):
Joshi refers to the contributions of individuals in the field of Ayurveda, particularly in research and education. This surname may indicate specific researchers or academics, such as Prof. V.K. Joshi, who have made notable contributions to studying plant medicine and traditional healing practices in Ayurvedic contexts.

23) Water:
Water is a foundational element in Ayurveda, essential for life and health. It is used as a solvent for extracting bioactive compounds from herbs during the preparation of medicinal formulations. The quality and purity of water are crucial for effective herbal extractions and effective treatment outcomes.

24) Study (Studying):
The term 'study' suggests detailed examination and research process, crucial in Ayurveda for validating traditional practices and formulations. Scientific studies, like those utilizing UV-Vis spectroscopy, help identify and quantify phyto-constituents in herbal preparations, bridging the gap between traditional knowledge and contemporary scientific validation.

25) Lamp:
In the context of spectroscopic analysis, the 'lamp' signifies the light source utilized in UV-Vis spectrophotometers. Different lamp types are used for UV and visible ranges to analyze chemical compounds, essential for identifying and understanding the bioactive phyto-constituents in herbal extracts.

26) Sushruta-samhita (Susruta-samhita):
Sushruta-samhita is an ancient text in Ayurveda attributed to Sushruta, often considered the father of surgery. It encompasses comprehensive knowledge about surgical techniques, anatomy, and medicinal plants, laying the groundwork for modern Indian surgery and medicinal practices, providing invaluable insights into ancient healthcare systems.

27) Phytochemical:
Phytochemicals are chemical compounds produced by plants, possessing significant health benefits. In Ayurveda, they are essential for understanding the properties and therapeutic potentials of various herbs. Studying phytochemicals through techniques like UV-Vis spectroscopy aids in identifying active compounds in Ayurvedic formulations, enhancing the science of herbal medicine.

28) Sutrasthana (Sutra-sthana):
Sutra-sthana is an important section of the Ayurvedic text, Sushruta Samhita, which deals with principles and practices of medicine. It outlines therapeutic approaches and guidelines for treatment, emphasizing foundational knowledge and practices within Ayurveda, serving as a crucial reference for practitioners and scholars alike.

29) Measurement:
In the context of Ayurveda, 'measurement' denotes the process of quantitatively analyzing herbal extracts and compounds using techniques such as UV-Vis spectroscopy. Accurate measurement of phyto-constituents is vital for standardizing formulations, ensuring consistent quality and efficacy in Ayurvedic treatments, thereby enhancing therapeutic outcomes.

30) Cakshushya (Caksusya):
Cakshushya is an Ayurvedic term often referring to substances beneficial for vision or eye health. Using specific herbs, including those in the Amalakyadi Gana, Ayurvedic practices aim to improve eyesight and maintain eye health, illustrating the holistic approach to health that Ayurveda promotes for bodily interconnectedness.

31) Discussion:
The term 'discussion' in academic contexts refers to the analysis and interpretation of study results. In Ayurveda research, discussing findings like those from UV-Vis spectroscopy helps elucidate the therapeutic potential of herbal constituents, promoting a deeper understanding of their roles in traditional medicine formulations and practices.

32) Jvarahara (Jvara-hara):
Jvarahara is a term in Ayurveda that signifies remedies effective against fever and related ailments. It highlights specific formulations and herbal combinations that can alleviate fever symptoms, showcasing Ayurveda's targeted approach to treatment through customized herbal blends for balancing dosha imbalances associated with febrile conditions.

33) Knowledge:
Knowledge in Ayurveda encompasses understanding traditional healing practices, medicinal plants, and their properties. It involves learning from ancient texts, contemporary research, and practical experience to apply Ayurvedic principles effectively in health maintenance and disease prevention, ensuring the continuity and evolution of this holistic medicinal system.

34) Activity:
Activity in Ayurveda relates to the beneficial effects or actions of herbal constituents on health. Analyzing the biological activity of phytochemicals, such as flavonoids and tannins through spectroscopic methods, aids in identifying their potential therapeutic applications, thereby supporting effective Ayurvedic treatments grounded in scientific validation.

35) Samhita:
Samhita refers to traditional Ayurvedic texts that compile extensive medical knowledge, theories, and practices. These texts serve as foundational resources for practitioners, detailing herbal medicine, surgical techniques, and holistic health principles, playing a critical role in preserving and disseminating Ayurvedic wisdom through generations.

36) Sadhana:
Sadhana denotes spiritual practice or discipline within Ayurveda and yoga contexts, aimed at achieving wellness and balance. It involves continuous effort to align one’s lifestyle with natural principles, encompassing health-promoting habits, dietary choices, and mindfulness practices, thereby enhancing physical, mental, and spiritual well-being.

37) Vrishya (Vrsya):
Vrishya refers to aphrodisiac substances in Ayurveda that enhance sexual vitality and reproductive health. These herbs and formulations aim to balance the body's energies and promote healthy reproductive functions. Ayurvedic medicine employs vrishya ingredients to support fertility, libido, and overall sexual well-being in a holistic context.

38) Rajiva:
Rajiva refers to specific plants or herbs relevant to Ayurveda localized in regions like India. It may also relate to traditional Ayurvedic texts or contexts where such plants are discussed concerning their medicinal properties, signifying the importance of local flora in the practice of Ayurvedic medicine.

39) Dipana:
In Ayurveda, 'Dipana' refers to the quality of enhancing digestive fire (Agni). This term is often associated with herbs and formulations that stimulate appetite and improve metabolism, helping to relieve conditions associated with poor digestion, thereby promoting overall health and well-being through effective digestive support.

40) Sthana:
Sthana signifies a location or place in Ayurveda, often referencing specific anatomical or physiological sites related to health and disease. Understanding sthana is essential for diagnosis and treatment, providing insights into where and how herbal remedies are intended to exert their therapeutic effects in the body.

41) Rashmi (Rasmi):
Rashmi could refer to a researcher or contributor in the field of Ayurveda, emphasizing the importance of collaborative efforts in understanding herbology, pharmacognosy, and their applications in modern health practices. Such individuals contribute to scientific research and documentation of traditional medicinal practices.

42) Powder:
In Ayurveda, 'powder' refers to the processed form of herbs used for therapeutic preparations. Herbal powders are central to preparing various medications and supplements, making them easier to administer and ensuring potency in delivering health benefits based on specific therapeutic principles and Ayurvedic formulations.

43) Kapha:
Kapha is one of the three doshas in Ayurveda, representing the elements of earth and water. It is associated with structure, stability, and fluid balance in the body. Understanding the attributes of Kapha helps in diagnosing health conditions and creating personalized Ayurvedic treatments for balancing this dosha.

44) Sutra:
Sutra translates to a verse or aphorism in Sanskrit, often referring to concise teachings in Ayurveda that encapsulate complex concepts. Sutras serve as foundational guidelines for practitioners, summarizing essential knowledge and practices related to health, medicine, and Ayurvedic philosophy, bridging ancient wisdom and contemporary understanding.

45) Jvara:
Jvara is the Ayurvedic term for fever, denoting both a symptom and a condition that results from imbalances in the body's doshas. Ayurvedic treatments for jvara focus on restoring balance through herbal interventions that alleviate symptoms and address the root cause of the fever, promoting overall wellness.

46) Campu:
Campu refers to a specific type of writing style used in ancient Ayurvedic texts, often involving poetic or compact verse forms to encapsulate medical knowledge. This literary style aids in memorization and dissemination of Ayurvedic principles, ensuring the longevity of traditional wisdom through generations.

47) Kumar:
Kumar typically refers to a male child or young person in Sanskrit, often appearing in Ayurvedic texts and contexts. This designation is significant in discussions or treatments related to pediatric health, emphasizing specialized knowledge and formulations targeting the health needs of children in traditional medicine.

48) Glass:
In the context of laboratory measurements and analyses, 'glass' refers to the materials used for creating containers and apparatus, such as beakers and flasks, essential for safely handling and examining herbal extracts in Ayurvedic research, enabling accurate and reliable scientific study of medicinal plants.

49) Fever:
Fever, or 'jvara' in Ayurveda, refers to an elevated body temperature often indicating an infectious or inflammatory condition. Ayurvedic approaches to treating fever emphasize restoring balance among the doshas and using specific herb-based formulations to address symptoms while supporting the body’s natural healing processes.

50) Carva:
Sarva translates to 'all' or 'every' in Sanskrit, emphasizing inclusivity in Ayurvedic practices and philosophy. It underscores the holistic approach taken in treatment formulations aimed at addressing the complete spectrum of health concerns for individuals, promoting overall well-being and balance across bodily systems.

51) Agni:
Agni, meaning 'digestive fire' in Sanskrit, is a fundamental concept in Ayurveda representing metabolism and digestion. It plays a crucial role in determining an individual's health and well-being. Balancing Agni is essential to preserving health, as strong digestion facilitates proper nutrient absorption and elimination of toxins.

52) Food:
Food, or 'anna', is a central aspect of Ayurvedic nutrition, impacting health directly through its qualities and effects on the doshas. Ayurveda emphasizes the importance of diet as a key factor in maintaining balance, promoting health, and preventing disease, guiding dietary choices based on individual needs and health conditions.

53) Dish (Dis):
In Ayurveda, 'dish' can refer to a meal or food preparation that embodies the principles of balanced nutrition. It highlights the importance of culinary practices in healing diets, where the preparation and selection of dishes consider the qualities of ingredients relevant to individual health and wellness goals.

Let's grow together!

I humbly request your help to keep doing what I do best: provide the world with unbiased sources, definitions and images. Your donation direclty influences the quality and quantity of knowledge, wisdom and spiritual insight the world is exposed to.

Let's make the world a better place together!

Like what you read? Consider supporting this website: