Study on Takzema tablet and ointment for vicharchika eczema.
Journal name: World Journal of Pharmaceutical Research
Original article title: Clinical study on the efficacy of takzema tablet and takzema ointment in the management of vicharchika eczema
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
This page presents a generated summary with additional references; See source (below) for actual content.
Summary of article contents:
Introduction
Eczema, referred to as Vicharchika in Ayurvedic medicine, is an inflammatory skin condition characterized by symptoms such as redness, itching, and dryness. The chronic nature of Vicharchika, classified under Kshudra Kustha in Ayurveda, poses significant challenges for treatment and management. In light of this, a study was conducted to evaluate the effectiveness of two formulations—Takzema Tablet for internal use and Takzema Ointment for external application—in alleviating the symptoms of Vicharchika. This approach aimed to leverage Ayurvedic principles and herbal ingredients to provide a safer, effective treatment for eczema compared to modern corticosteroid treatments.
Takzema Formulations and Their Efficacy
The Takzema formulations are designed to address the underlying pathology of Vicharchika by utilizing a blend of herbs known for their therapeutic properties. Ingredients such as Neem and Guduchi in the Takzema Tablet aim to modulate the immune response and reduce inflammatory symptoms, while the ointment contains natural ingredients like Haridra and Aloe Vera, which enhance skin barrier functions. The combined use of these formulations is based on a holistic view of treating eczema, targeting symptom relief while promoting skin health. The study highlighted the significant improvement in symptoms, showing high efficacy through both subjective and objective assessments.
Study Methodology and Patient Demographics
The study was conducted on 15 patients diagnosed with Vicharchika, selected from the outpatient and inpatient departments of the National Institute of Ayurved in Jaipur. Inclusion criteria specified patients aged between 16 and 70 years with eczema symptoms persisting for less than five years. Various subjective parameters, such as itching (Kandu), burning sensation (Daha), oozing (Srava), and others, were measured using a defined scoring system before and after treatment. The study also considered population demographics, with a predominance of young male patients and various socio-economic backgrounds, thus providing insights into those most affected by this condition.
Results and Statistical Analysis
The results of the study demonstrated a significant reduction in symptoms across various subjective parameters. The mean scores for Kandu, Srava, and Daha peaked at 82.19%, 41.74%, and 60.15% relief, respectively, proving the efficacy of the Takzema formulations. Statistical analysis employing tests like the Wilcoxon matched-pairs signed ranks test showed high significance in the relief experienced by patients. The study also noted that Kandu and Raji (thickening of skin) exhibited particularly marked improvements, reinforcing the formulations' effectiveness in treating chronic skin conditions like eczema.
Conclusion
The findings from the study underscore the potential of Takzema Tablet and Ointment as effective Ayurvedic remedies for managing Vicharchika, presenting a viable alternative to conventional steroid treatments that often carry risk of serious side effects. With significant improvements observed in symptoms like itching, oozing, and skin discoloration, the study advocates for a deeper exploration of herbal combinations in treating chronic dermatological issues. This holistic approach not only highlights the efficacy of Ayurvedic practices but also suggests that integrating traditional knowledge with modern healthcare could lead to more sustainable and safer treatment options for conditions like eczema.
Original source:
This page is merely a summary which is automatically generated hence you should visit the source to read the original article which includes the author, publication date, notes and references.
Dr. Arya Neelam, Sharma Anita and Saini Rashmi
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Clinical study on the efficacy of takzema tablet and takzema ointment in the management of vicharchika eczema
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr201710-9294
Download the PDF file of the original publication
FAQ section (important questions/answers):
What is Vicharchika in Ayurveda and its modern equivalent?
Vicharchika is an Ayurvedic term for eczema, characterized by skin inflammation. It corresponds clinically to eczema in modern medicine, presenting with symptoms such as redness, itching, and dryness.
How are Takzema tablet and ointment used in treatment?
Takzema tablet is taken orally for internal management, while Takzema ointment is applied externally. Together, they aim to alleviate the symptoms of Vicharchika by addressing its underlying pathology.
What are the main symptoms of Vicharchika (eczema)?
Key symptoms of Vicharchika include itching (Kandu), oozing (Srava), dryness (Rukshta), discoloration (Vaivarnyata), and skin thickening (Raji), leading to discomfort and distress.
What symptoms showed significant relief after using Takzema formulations?
Significant relief was observed in symptoms like itching (82.19%), burning (60.15%), and discoloration (43%) after treatment with Takzema formulations, indicating their efficacy.
What types of patients were included in the study?
The study included patients aged 16-70 with Vicharchika symptoms lasting less than 5 years. Exclusions applied to those with severe concurrent illnesses or long-term steroid use.
What are the properties of the ingredients in Takzema products?
Ingredients in Takzema have various properties, including anti-inflammatory, antibacterial, and blood-purifying effects, contributing to the effective management of Vicharchika symptoms.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Study on Takzema tablet and ointment for vicharchika eczema.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Ushna (Usna):
In Ayurvedic context, 'Ushna' means 'hot' or 'warm.' This quality is often attributed to certain herbal drugs that have properties aiding in eliminating vitiated doshas, particularly Kapha and Vata. Ushna properties stimulate digestion and absorption, making such drugs effective in treating disorders like Vicharchika (eczema) by enhancing metabolic processes.
2) Drug:
'Drug' refers to any substance used for medical purposes, especially in healing or preventing diseases. In Ayurveda, drugs can be herbal or mineral-based. In this study, 'Takzema tablet' and 'Takzema ointment' are highlighted as specific formulations used to treat Vicharchika, showcasing the significance of effective Ayurvedic drugs.
3) Ruksha (Ruksa):
'Ruksha' means 'dry' in Ayurveda and describes certain qualities of substances. Substances with Ruksha properties are essential in treating skin disorders that display dryness or scaling, such as Vicharchika. Ruksha helps reduce moisture accumulation, thereby alleviating symptoms like itching and invasion by doshas in skin diseases.
4) Nilam:
'Neelam' refers to a person, in this context, Dr. Arya Neelam, one of the researchers contributing to the study. As an Ayurvedic scholar, Dr. Neelam plays a critical role in exploring ancient texts and applying traditional knowledge in modern clinical settings for conditions like Vicharchika (eczema).
5) Katu:
'Katu' signifies 'pungent' or 'bitter' in Ayurveda, relating to the taste of certain herbs. This property is vital as Katu drugs can help in alleviating symptoms of excessive Kapha and Pitta doshas in disorders such as Vicharchika. These substances often stimulate appetite and enhance digestion.
6) Laghu:
'Laghu' translates to 'light' and describes the quality of certain substances that can aid digestion or absorption. In Ayurveda, Laghu substances are considered beneficial as they promote quick metabolic movement, making them effective for treating slower, stagnated conditions such as eczema.
7) Itching:
'Itching' or 'Kandu' is one of the primary symptoms associated with Vicharchika (eczema). This symptom presents as an intense urge to scratch. Understanding its nature and managing the itching is crucial in Ayurvedic treatment approaches, aiming to provide relief without causing skin damage.
8) Kushtha (Kustha):
'Kushtha' is a term used to denote skin diseases in Ayurveda. Understanding Kushtha is crucial for practitioners, as it encompasses various chronic conditions requiring specific attention, including Vicharchika, guiding treatment methodologies.
9) Kashaya (Kasaya):
'Kasaya' refers to astringent taste in Ayurveda, often linked to various healing properties of herbs. Kasaya herbs are valuable for constraining excess discharge and inflammation in skin conditions like Vicharchika, promoting healing by combatting vitiated doshas affecting the skin.
10) Tikta:
'Tikta' translates to 'bitter' and signifies a taste that is often linked with detoxifying and cleansing actions in Ayurvedic treatment. Ingredients with Tikta properties are crucial for managing skin ailments. They can help in purging toxins from the body, particularly beneficial for conditions such as eczema.
11) Kandu (Kamdu):
'Kandu' means 'itching' and is a major symptom in skin diseases like eczema. Its presence signals the vitiation of doshas, primarily Pitta. In Ayurvedic treatments, understanding Kandu's intensity helps in personalizing the therapeutic approach to provide effective relief from discomfort.
12) Study (Studying):
'Study' refers to the research conducted by the authors to evaluate the efficacy of 'Takzema' in treating Vicharchika. This study utilizes clinical evaluation and scientific methods to assess both subjective and objective parameters, thereby contributing to holistic approaches in managing skin disorders.
13) Ayurveda (Ayus-veda):
'Ayurveda' is an ancient Indian system of medicine that focuses on holistic healing using natural remedies. It emphasizes balancing the doshas (Vata, Pitta, Kapha) to ensure optimal health. Through the application of herbal drugs, Ayurveda aims to restore equilibrium and prevent chronic conditions like Vicharchika.
14) Shrava (Srava):
'Srava' denotes 'oozing' or 'discharge' and is a common symptom in conditions like eczema. Understanding the nature and extent of Srava helps practitioners monitor the severity of Vicharchika, guiding effective treatment modalities aimed at reducing inflammation and promoting healing.
15) Activity:
'Activity' refers to the physiological responses or functions of the body affected during the disease process. Monitoring changes in activity relates to the improvement of symptoms in patients undergoing treatment for Vicharchika and helps assess the overall effectiveness of the applied regimens.
16) Disease:
'Disease' is a pathological condition with a specific set of symptoms and causes. Vicharchika, categorized under Kustha in Ayurveda, showcases chronic characteristics that require extensive management approaches for effective relief. Understanding its presentation supports targeted therapeutic methods.
17) Pitta:
'Pitta' represents one of the three doshas in Ayurveda, associated with heat, transformation, and digestion. In Vicharchika, Pitta plays a significant role due to its relation to inflammation and skin conditions. Managing Pitta is essential in ameliorating eczema symptoms effectively.
18) Varanasi (Varanashi):
'Varanasi' is a prominent city in India known for its historical significance and contribution to Ayurveda. Research conducted in places like Varanasi often integrates traditional practices with contemporary scientific exploration, enhancing the understanding of conditions such as Vicharchika.
19) Medicine:
'Medicine' encompasses substances used for therapeutic purposes, including natural remedies in Ayurveda. Here, Takzema (both tablet and ointment) is highlighted as a targeted treatment for Vicharchika, showcasing the integration of traditional knowledge in modern medicinal practices.
20) Madhura:
'Madhura' refers to 'sweet' and is one of the six tastes in Ayurveda associated with soothing properties. Medicinal herbs with Madhura properties can help counterbalance harmful effects caused by Pitta and Kapha vitiation, promoting stability and gastrointestinal health.
21) Kshudra (Ksudra):
'Kshudra' denotes minor systemic diseases and is used to classify certain skin disorders in Ayurveda. Vicharchika falls under this category, showcasing its chronic nature that, while often manageable, can present challenges in achieving complete and long-lasting resolution.
22) Snigdha:
'Snigdha' means 'unctuous' or 'oily' and describes the properties of some herbs. In the treatment of Vicharchika, Snigdha qualities are beneficial in soothing irritation, enhancing skin hydration, and fostering recovery from dryness related to skin conditions.
23) Burning (Burn, Burned, Burnt):
'Burning' or 'Daha' is a symptom associated with inflammation and discomfort in skin conditions. Addressing burning sensations is crucial in managing eczema. Treatment often emphasizes balancing Pitta to alleviate such distressing sensations experienced by patients.
24) Kapha:
'Kapha' is the third dosha in Ayurveda, embodying earth and water elements, often linked to stability and structure. In Vicharchika, Kapha's vitiation significantly contributes to symptoms like itching and oozing, thus its balance is critical in treatment.
25) Guru:
'Guru' means 'heavy,' referring to substances that are difficult to digest or metabolize. Some Ayurvedic drugs possess Guru qualities, which can be beneficial for certain conditions but may aggravate others, hence requiring careful selection in treating Vicharchika.
26) Guna:
'Guna' translates to 'quality' or 'attribute' and encompasses various characteristics of substances in Ayurveda. Understanding Guna is essential for practitioners as it aids in selecting appropriate herbs for individualized treatment plans in disorders like Vicharchika.
27) Raji:
'Raji' refers to thickening or lichenification of the skin, a common sign of chronic skin diseases such as eczema. Its evaluation helps gauge the severity of conditions like Vicharchika and assists in monitoring the effectiveness of ongoing treatment.
28) Daha:
'Daha' denotes burning sensation, often linked to inflammation. This symptom is significant in Vicharchika, providing insight into the underlying dosha imbalances. Managing Daha helps in alleviating patient discomfort and enhancing skin healing.
29) Sign:
'Sign' relates to observable manifestations of a disease, vital for diagnosis and treatment planning. In Vicharchika, signs like itching and oozing guide Ayurvedic practitioners in tailoring interventions to support effective disease management.
30) Prakriti (Prakrti):
'Prakriti' refers to an individual's constitution, shaped by dosha predominance. Understanding Prakriti helps Ayurvedic practitioners personalize treatments for conditions like eczema, considering individual attributes when selecting herbal formulations for optimal outcomes.
31) Sanskrit:
'Sanskrit' is the ancient language of India, in which many Ayurvedic texts are written. Understanding this language is essential for interpreting classical texts effectively and applying traditional knowledge to modern medical practices, such as in treating Vicharchika.
32) Samhita:
'Samhita' refers to a collection or compilation of texts, particularly pertaining to Ayurveda. The Sushruta Samhita, for example, provides foundational concepts for diagnosing and treating disorders like Vicharchika, emphasizing traditional knowledge applied in clinical settings.
33) Alavana:
'Alavana' denotes the taste of herbs that possess specific attributes. It can refer to substances used in Ayurvedic preparations that help balance doshas. Knowledge of taste properties (like Alavana) is crucial for creating specific formulations for managing skin conditions.
34) Science (Scientific):
'Science' refers to a systematic enterprise that builds and organizes knowledge. In the context of Ayurveda, it underlines the analytical approach to understanding herbal remedies and their medicinal applications, blending traditional wisdom with modern research methodologies.
35) Jaipur:
'Jaipur' is a city in Rajasthan, India, affiliated with the National Institute of Ayurveda where the study was conducted. Its rich heritage in Ayurveda contributes to ongoing research and development in traditional medicine applications for diseases like Vicharchika.
36) Pidika:
'Pidika' refers to the pustules or blisters that form in skin conditions like eczema. Observing the presence of Pidika helps in assessing the stage and severity of Vicharchika, which influences treatment strategies aimed at managing these visible symptoms.
37) India:
'India' is the birthplace of Ayurveda, with traditions that have been practiced for thousands of years. The country's diverse flora provides a rich source of medicinal herbs used in various formulations, pivotal in managing diseases like Vicharchika.
38) Vata:
'Vata' is one of the three doshas in Ayurveda, associated with air and movement. Its imbalance can lead to various skin disorders, including Vicharchika. Understanding Vata’s role is essential in creating effective interventions during treatment.
39) Emblica officinalis:
Emblica officinalis, commonly known as Amla, is an Ayurvedic herb recognized for its antioxidant properties. Its significance in formulations like Takzema is vital for skin health. Amla supports the rejuvenation and detoxification of the skin, helping mitigate chronic conditions like eczema.
40) Berberis aristata:
Berberis aristata, or Daruharidra, is an important herb in Ayurveda known for its antimicrobial and anti-inflammatory properties. This herb is utilized in formulations like Takzema to treat skin conditions such as Vicharchika, aiding in wound healing and inflammation reduction.
41) Curcuma longa:
Curcuma longa, commonly referred to as turmeric, is celebrated in Ayurveda for its potent anti-inflammatory and healing properties. Integrated into treatments like Takzema, it provides crucial support in managing skin disorders by promoting healing and reducing inflammation.
42) Sushruta-samhita (Susruta-samhita):
The Sushruta Samhita is a foundational Ayurvedic text focusing on surgery, medicine, and comprehensive treatment strategies. It includes valuable insights on skin illnesses like Vicharchika, serving as a reference for practitioners to understand and apply holistic healing.
43) Antibiotic (Antibacterial):
'Antibacterial' refers to the property of preventing bacterial growth. In treating Vicharchika, herbs with antibacterial properties are essential to avoid infections, especially in compromised skin. This characteristic enhances the effectiveness of herbal formulations used in dermatological treatments.
44) Daruharidra (Daru-haridra):
Daruharidra, or Berberis aristata, is recognized for its healing properties in Ayurveda. Known for its antimicrobial effects, it serves an essential role in formulations like Takzema, promoting skin healing while preventing infections commonly associated with chronic conditions like Vicharchika.
45) Scratching:
'Scratching' is a common response to itching and can exacerbate skin conditions like eczema. Effective management must address scratching behaviors. Interventions aim to reduce itching and subsequent scratching to prevent skin damage and allow healing.
46) Rajasthan:
'Rajasthan' is a region in India known for its rich Ayurvedic traditions and practices. The research conducted in this region highlights the application of traditional medicine to address conditions like Vicharchika, showcasing the significance of local Ayurvedic knowledge.
47) Tridosha (Tridosa, Tri-dosha):
'Tridosha' refers to the three doshas in Ayurveda: Vata, Pitta, and Kapha. Each individual's health is influenced by the balance of these doshas. Identifying dosha imbalances is critical in treating conditions such as Vicharchika effectively.
48) Haridra:
'Haridra,' or turmeric, possesses significant anti-inflammatory and antioxidant properties. In treating skin conditions like Vicharchika, Haridra plays a crucial role in promoting skin health, reducing inflammation, and aiding wound healing through its therapeutic properties.
49) Tantra (Tamtra, Tantrism):
'Tantra' translates to 'treatment method' in Ayurveda. It encompasses various techniques and practices used to restore balance among doshas. Understanding Tantras is essential for effective patient treatment, especially for chronic conditions like Vicharchika.
50) Dushya (Dusya):
'Dushya' refers to the pathological entities or substrates contributing to disease manifestation. In Vicharchika, understanding the Dushya helps practitioners identify and address underlying issues, facilitating unique treatment methodologies tailored to the disorder's nature.
51) Dosha (Dosa):
'Dosha' is a fundamental concept in Ayurveda representing physiological principles that govern bodily functions. The balance or imbalance of doshas—Vata, Pitta, and Kapha—can impact skin health profoundly. Understanding dosha dynamics is essential in treating conditions like Vicharchika effectively.
52) Rakta:
'Rakta' signifies 'blood' in Ayurveda and plays a critical role in nourishing the body's tissues. In treating skin diseases like Vicharchika, maintaining Rakta's quality is essential to ensure optimal healing and prevent/toxicity and inflammation in underlying conditions.
53) Road:
'Road' may refer to the pathway of pursuing Ayurvedic knowledge and practices. Its significance encompasses navigating through life's challenges while exploring health aspects through traditional medicine, especially in understanding chronic conditions like Vicharchika.
54) Terminalia chebula:
Terminalia chebula, known as Haritaki, is an important herb in Ayurvedic formulations. It possesses detoxifying and rejuvenating properties, making its incorporation in treatments like Takzema essential for restoring skin health and enhancing overall well-being.
55) Rubia cordifolia:
Rubia cordifolia, or Manjistha, is an Ayurvedic herb known for its blood-purifying effects. Its incorporation into formulations like Takzema plays a crucial role in alleviating skin conditions such as Vicharchika by enhancing skin healing and reducing inflammation.
56) Madhavakara:
'Madhavakara' is an esteemed figure in Ayurvedic literature, contributing to texts focused on diseases and treatments. His works help practitioners understand chronic conditions and provide frameworks for treatment, including for illnesses like Vicharchika, enhancing traditional practices.
57) Vatapitta (Vata-pitta):
'Vata-pitta' refers to a combination of dosha characteristics in Ayurveda. Individuals with this constitution display attributes of both Vata (movement) and Pitta (transformation). Understanding this balance aids in creating targeted treatments for conditions like eczema, paving the way for tailored therapeutic approaches.
58) Discussion:
'Discussion' refers to the analytical exploration of findings within the study context. It encapsulates the elaboration of results, comparing them with existing literature, and suggesting practical implications of the research related to Vicharchika management in Ayurvedic practice.
59) Irritation:
'Irritation' signifies discomfort or inflammation in the skin, a common symptom of conditions like Vicharchika. Understanding its causes paves the way for effective management strategies that address both the symptom and its underlying dosha imbalance.
60) Krimighna (Krmighna, Krimi-ghna):
'Krimighna' refers to the property of eliminating microbes and parasites. In Ayurvedic treatments for Vicharchika, the use of Krimighna herbs is crucial to prevent secondary infections, thereby promoting healing and reducing the overall burden of the disease.
61) Kandughna (Kandu-ghna):
'Kandughna' refers to the property of alleviating itching. The use of Kandughna herbs in treating eczema is significant as it directly addresses one of the most distressing symptoms of the condition, helping to enhance the patient's quality of life.
62) Upadhyaya:
'Upadhyaya' refers to a teacher or a learned person, usually in the context of traditional education. This term holds significance in Ayurvedic practices, where knowledgeable figures guide practitioners in understanding complex concepts relevant to diseases like Vicharchika.
63) Vitiation (Vitiated):
'Vitiated' refers to the disturbed balance of doshas contributing to disease. In Ayurveda, identifying vitiated states in patients helps practitioners develop personalized treatments that target restoring harmony, particularly in chronic conditions like Vicharchika.
64) Haritaki:
Haritaki, known scientifically as Terminalia chebula, is a cherished herb in Ayurveda valued for its detoxifying and rejuvenating properties. It is commonly used in formulations to combat inflammation and support digestive health, making it instrumental in treating Vicharchika effectively.
65) Rukshata (Ruksata):
'Rukshata' means 'dryness' in Ayurveda and is a key symptom in certain skin diseases. Identifying Rukshata’s presence assists practitioners in tailoring treatments aimed at moisturizing and soothing the skin while addressing underlying dosha imbalances.
66) Rasayana (Rasa-ayana):
'Rasayana' refers to rejuvenative therapies in Ayurveda focused on revitalizing body tissues and enhancing immunity. Incorporating Rasayana practices can improve overall skin health and vitality, essential when addressing chronic conditions such as Vicharchika.
67) Madhava:
'Madhava' refers to another revered figure in Ayurvedic literature, contributing knowledge related to herbal therapies. His insights underscore the importance of traditional wisdom in managing skin diseases and fostering a deeper understanding of treatment methodologies.
68) Pradhan:
'Pradhan' can mean 'chief' or 'primary' and is often used to describe the leading aspects of treatments in Ayurveda. Recognizing the Pradhan properties of certain herbs helps practitioners emphasize their dominant characteristics when managing conditions like Vicharchika.
69) Kumari:
'Kumari' translates to 'Aloe vera,' known for its soothing and moisturizing properties. In treating conditions like Vicharchika, incorporating Kumari helps in alleviating symptoms like dryness and irritation, promoting healthier skin during the healing process.
70) Family:
'Family' refers to the taxonomical classification used in botany. Understanding the family of medicinal herbs aids in identifying potential therapeutic applications for their constituents within Ayurvedic medicine, enhancing the efficacy of formulations for treating conditions like Vicharchika.
71) Nature:
'Nature' encompasses the inherent qualities and characteristics of substances or conditions. Recognizing the nature of patient conditions is crucial in Ayurveda, as it influences diagnosis and treatment practices tailored to restoring balance and harmony in the body.
72) Virya:
'Virya' refers to the potency or energy of a substance in Ayurveda. Understanding the Virya of medicinal herbs aids practitioners in choosing appropriate remedies, ensuring that treatments for conditions like Vicharchika are effective and align with individual needs.
73) Table:
'Table' denotes organized data presentation in research contexts. Tables effectively summarize findings, illustrating patterns, comparisons, and outcomes rooted in statistical analysis, helping readers comprehend the results of studies like the one evaluating Takzema's efficacy.
74) Arya:
'Arya' references Dr. Arya Neelam, a lead researcher in the study. As a PG Scholar, her role emphasizes the integration of Ayurvedic principles with modern empirical research, promoting effective treatments for chronic skin conditions like Vicharchika.
75) Neem:
'Neem' refers to Azadirachta indica, a key ingredient in many Ayurvedic formulations. Known for its antibacterial and anti-inflammatory properties, Neem is an essential component in the management of skin conditions like Vicharchika, aiding in itching and irritation relief.
[Note: The above list is limited to 75. Total glossary definitions available: 147]