Effect of bhadranimbakulathadi basti on insulin resistance syndrome
Journal name: World Journal of Pharmaceutical Research
Original article title: Effect of bhadranimbakulathadi basti in kaphaj nanatmaj vyadhi w. s. r. t. insulin resistance syndrome
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Dr. Vaidya Meenakshi Rewadkar Kole and Vaidya Neelam Dinesh Sali
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Effect of bhadranimbakulathadi basti in kaphaj nanatmaj vyadhi w. s. r. t. insulin resistance syndrome
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr201714-9957
Download the PDF file of the original publication
Summary of article contents:
Introduction
The study published in the World Journal of Pharmaceutical Research focuses on the efficacy of Bhadranimbakulathadi Basti in treating Insulin Resistance Syndrome, particularly in the context of Kaphaj Nanatmaj Vyadhi, an Ayurvedic classification of diseases. With modern lifestyles leading to increased cardiovascular diseases, diabetes, and related metabolic disorders, it highlights how contemporary dietary habits and stress contribute to insulin resistance. The authors, Dr. Meenakshi Rewadkar Kole and Dr. Neelam Dinesh Sali, conducted a prospective, open, randomized study involving 30 patients, aiming to evaluate the impact of a specific Ayurvedic treatment.
Effect of Bhadranimbakulathadi Basti on Insulin Levels
The study specifically analyzed how Bhadranimbakulathadi Basti affects serum insulin levels in patients with Insulin Resistance Syndrome. After administering two cycles of the treatment with a gap of eight days in between, results showed a significant reduction in fasting serum insulin levels, decreasing by an average of 7.395±5.656 µIU/ml, with a statistically significant p-value of <0.0001. Symptoms associated with insulin resistance such as heaviness, lethargy, excessive sleep, and weakness also showed considerable improvement post-treatment, underscoring the method's potential effectiveness in ameliorating symptomatic conditions of insulin resistance.
Ayurvedic Concepts of Metabolism and Insulin Resistance
The study contextualizes Insulin Resistance Syndrome with Ayurvedic principles, correlating the syndrome to Kaphaj Nanatmaj Vyadhi, characterized by metabolic disruptions due to poor dietary choices and lifestyle. According to Ayurveda, disorders stem from a disturbance in Rasa dhatvagni, leading to improper metabolism and the formation of Ama, a toxic substance that disrupts physiological processes. The research links insulin resistance to the dysfunction of metabolic fires (Agnis) at various levels, causing an accumulation of excess Kapha and Meda dhatu and ultimately resulting in health complications that are akin to those described in modern-day metabolic syndrome.
Patient Demographics and Treatment Outcomes
In addition to the analysis of biochemical parameters, the study presented demographic information about participants. Patients predominantly fell within the 31-50 year age range, with a notable prevalence among females from middle-income backgrounds. A significant portion of participants (53.33%) had a history of medication for conditions related to Insulin Resistance Syndrome. The findings indicated a promising outcome, with the majority of patients—75%—showing notable enhancement in their condition, reflecting the potential of traditional Ayurvedic treatments in managing modern health issues.
Conclusion
The study concludes by asserting that Bhadranimbakulathadi Basti is an effective intervention for reducing serum insulin levels and alleviating symptoms associated with Insulin Resistance Syndrome. With a notable impact on health parameters and quality of life, the research advocates for the consideration of Ayurvedic therapies as viable treatment options to address metabolic disorders in a contemporary context. In light of increasing obesity and lifestyle-related diseases, incorporating such traditional practices could offer a complementary approach to modern medicine in managing and preventing insulin resistance and its associated complications.
FAQ section (important questions/answers):
What is Insulin Resistance Syndrome as described in the study?
Insulin Resistance Syndrome is a modern metabolic disorder characterized by disturbed metabolism, resulting from factors like dietary habits, lack of exercise, and stress, leading to conditions such as diabetes, hypertension, and dyslipidaemia.
What treatment was evaluated for Insulin Resistance Syndrome in the study?
The study evaluated the effects of Bhadranimbakulathadi Basti, a therapeutic enema involving Ayurvedic principles, on serum insulin levels in patients diagnosed with Insulin Resistance Syndrome and Kaphaj Nanatmaj Vyadhi.
What were the preliminary criteria for including patients in the study?
Patients aged 16-60 with serum insulin levels between 25-50 µIU/ml and symptoms like gaurava and alasya were included. They should not have severe renal issues, acute complications, or type 1 diabetes.
What significant results were found after the treatment with Bhadranimbakulathadi Basti?
The treatment significantly decreased serum insulin levels by an average of 7.395±5.656 µIU/ml, and improvement was noted in symptoms like heaviness and fatigue, indicating the efficacy of the therapy.
How was the symptom relief measured in the study?
Symptom relief was assessed using a four-point scale based on severity and duration of symptoms, with both objective serum insulin levels and subjective patient-reported outcomes evaluated.
Why is Ayurveda relevant to modern metabolic disorders according to the study?
Ayurveda addresses issues like improper dietary habits, metabolism disturbances, and obesity, offering natural therapies like Panchakarmas that may effectively manage modern diseases such as Insulin Resistance Syndrome.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Effect of bhadranimbakulathadi basti on insulin resistance syndrome”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Rasa (Rasha):
Rasa refers to the primary post-digestive fluid derived from food that nourishes the body in Ayurveda. It includes essential nutrients and serves as a basis for all bodily elements. Rasa's quality and balance are critical to maintaining health, as it directly influences the creation and health of dhatus (tissues).
2) Kapha:
Kapha is one of the three doshas in Ayurveda, representing the elements of water and earth. It governs the body's structure, such as bones and muscles, and the fluid balance, providing stability and nourishment. An imbalance in Kapha can lead to obesity, lethargy, and other health issues.
3) Dhatu:
Dhaatu signifies tissue or elemental structures forming the physical body in Ayurveda. Their balance and health are vital for overall functioning, guiding treatment and dietary instructions.
4) Disease:
In Ayurveda, disease (roga) is understood as an imbalance of doshas, dhatus, and the metabolism (agni). The prevention and treatment of disease focus on restoring balance through natural therapies, including dietary adjustments and treatments like Panchakarma, emphasizing holistic health and well-being.
5) Dosha (Dosa):
Dosha represents the three biological energies (Vata, Pitta, and Kapha) that govern physiological and psychological processes in the body. Each individual has a unique dosha constitution, and maintaining harmony among these is essential for health, while imbalances can lead to disease.
6) Rakta:
Rakta refers to the blood dhatu in Ayurveda, responsible for transporting nutrients and oxygen throughout the body. It also plays a role in the immune response and overall vitality. Its quality impacts various bodily functions, including energy levels and emotional well-being.
7) Vaidya:
A Vaidya is an Ayurvedic physician or practitioner who diagnoses and treats ailments based on the principles of Ayurveda. Their role includes a deep understanding of herbs, dietary interventions, and traditional therapies to help restore balance and promote healing.
8) Vitiation (Vitiated):
Vitiation refers to the impairment or disturbance of doshas, dhatus, or bodily functions in Ayurveda. Understanding vitiation is critical for diagnosing diseases and developing effective treatment strategies.
9) Basti:
Basti refers to an Ayurvedic therapeutic enema, used as a Panchakarma treatment. It involves administering medicated liquids to cleanse and rejuvenate the body, especially for conditions related to Vata imbalance. Basti is considered effective for detoxification and nourishment.
10) Kaphadosha (Kaphadosa, Kapha-dosha):
Kaphadosha signifies a primary dosha linked to structure and fluid balance. Understanding Kaphadosha's role is vital for maintaining bodily harmony, with imbalances leading to conditions such as obesity and lethargy.
11) Rasadhatu (Rasa-dhatu):
Rasa-dhatu refers to the plasma or bodily fluid essential for nourishing tissues. It represents the first stage of digestion and is responsible for distributing nutrients throughout the body. The health of Rasa influences overall vitality and equilibrium in bodily functions.
12) Snigdha:
Snigdha is a Sanskrit term meaning 'unctuous' or 'oily.' In Ayurveda, substances with Snigdha properties are nourishing and soothing, promoting moisture and balance. It has therapeutic implications, especially for conditions involving dryness or roughness in the tissues.
13) Medas (Meda, Medash):
Meda is the fat dhatu in Ayurveda, crucial for energy storage, insulation, and protection of vital organs. Its balance is essential for bodily functions, and excess Meda can lead to obesity and other health concerns linked with metabolic disorders.
14) Guna:
Guna refers to the inherent qualities or attributes of substances in Ayurveda. Understanding Guna helps assess the properties of food, herbs, and the body's elements, guiding therapeutic decisions for restoring balance and health.
15) Guru:
Guru denotes a quality of heaviness in Ayurveda, applicable to both foods and bodily substances. Heavy (Guru) substances can impact digestion and metabolism, with implications for conditions like obesity and sluggishness if consumed excessively.
16) Dhatvagni (Dhatu-agni):
Dhatvagni refers to the metabolic fire at the tissue level. It plays a pivotal role in transforming nutrients into dhatus. A balance in Dhatvagni is necessary for healthy tissue metabolism, whereas its dysfunction can contribute to diseases.
17) Ahara:
Ahara signifies food or dietary intake in Ayurveda. It is considered a fundamental pillar of health, as proper nutrition harmonizes bodily functions. Ahara's quality directly influences the formation of Rasa, and thus overall health and vitality.
18) Rasayani:
Rasayani indicates substances or therapies that promote Rasadhatvagni, enhancing the transformation and utilization of nutrients in the body. Rasayani treatments are aimed at rejuvenating and nourishing the body, improving health and wellness.
19) Study (Studying):
The study refers to systematic research examining the effects of specific treatments or therapies, such as Bhadranimbakulathadi Basti on insulin levels. Through controlled trials, it aims to validate Ayurvedic principles and explore holistic approaches to modern health issues.
20) Prameha:
Prameha is a term in Ayurveda that encompasses various conditions related to excessive urination and metabolic disorders, often linked to diabetes. It signifies an imbalance in Kapha and other doshas, requiring careful management of diet and lifestyle.
21) Dhamani:
Dhamani refers to the channels or vessels in the body through which blood and other fluids circulate. Proper functioning of Dhamani is crucial for maintaining healthy circulation and overall bodily health, linking to the concepts of Srotasas.
22) Vyadhin (Vyadhi):
Vyadhi denotes disease or ailment in Ayurveda, recognized as a disturbance in the balance of doshas and dhatus. Understanding Vyadhi is essential for diagnosis and treatment, guiding practitioners in restoring harmony and promoting healing.
23) Agni:
Agni represents the digestive fire or metabolic energy in Ayurveda. It is essential for digestion, absorption, and transformation of food into vital energy. Balancing Agni is crucial for maintaining health and preventing disease.
24) Food:
Food encompasses all dietary substances consumed for nourishment. In Ayurveda, the quality and type of food significantly influence health, metabolism, and the formation of doshas and dhatus, thus playing a crucial role in preventing and treating ailments.
25) Ayurveda (Ayus-veda):
Ayurveda is an ancient system of medicine originating from India, focusing on holistic health and well-being. It emphasizes balance among the body's doshas, dhatus, and agni, utilizing natural therapies, dietary practices, and lifestyle modifications for optimal health.
26) Sthaulya:
Sthaulya refers to obesity in Ayurveda, characterized by excessive accumulation of Meda dhatu and vitiated Kapha dosha. It is associated with a sedentary lifestyle and improper dietary habits, requiring a multifaceted treatment approach for management.
27) Madhura:
Madhura refers to a sweet taste in Ayurveda, which is one of the six tastes. Foods with Madhura qualities can provide nourishment and energy, but excess consumption can lead to imbalances, contributing to conditions like diabetes.
28) Mala:
Mala denotes waste products or excretions in Ayurveda, including urine and feces. Proper elimination of Mala is essential for health, as accumulation or vitiation can lead to toxicity and disease. Maintaining balance in Mala is a vital aspect of Ayurvedic health.
29) Jatharagni (Jathara-agni):
Jatharagni is the primary digestive fire located in the stomach. It plays a critical role in digesting food and assimilating nutrients. A well-functioning Jatharagni is vital for maintaining overall health and preventing digestive disorders.
30) Sevana:
Sevana refers to the practice of consumption or indulgence in certain foods or activities. In Ayurveda, appropriate Sevana is crucial for ensuring balance in doshas and dhatus, influencing health outcomes and treatment effectiveness.
31) Kleda:
Kleda represents moisture or humidity in Ayurveda. It is an important factor in understanding various diseases, particularly those involving excess Kapha dosha, and the management of conditions like obesity and water retention.
32) Raja:
Raja encompasses the reproductive dhatu related to blood in Ayurveda. Its balance is vital for fertility and hormonal health, influencing overall vitality and well-being, as disturbances in Raja can lead to reproductive disorders.
33) Blood:
Blood, or Rakta, is a major dhatu in Ayurveda responsible for nourishing tissues and maintaining vitality. Its properties and quality heavily influence health dynamics, including emotional and physical well-being.
34) Hetu:
Hetu refers to the cause or reason for a particular condition or disease in Ayurveda. Understanding Hetu is vital for diagnosis and treatment as it guides therapeutic decisions to restore balance and health.
35) Sign:
Sign indicates observable symptoms or markers of a particular condition or disease. In Ayurveda, recognizing signs helps practitioners identify imbalances in doshas or dhatus, informing appropriate treatment strategies.
36) Medadhatu (Meda-dhatu):
Medadhatu signifies fatty tissue in Ayurveda, vital for energy storage and protection. Balancing Medadhatu levels is necessary to avoid obesity and related health concerns.
37) Sharira (Sarira):
Sarira indicates the physical body within Ayurvedic philosophy. Recognizing the complexities of Sarira helps in understanding bodily functions and interactions critical for health.
38) Dushya (Dusya):
Dusya refers to the components affected in a disease, essential to recognize for tailored treatment in Ayurveda. Understanding Dusya aids in identifying the underlying issues.
39) Styana:
Styana indicates stagnation or a lack of movement within the body. In Ayurveda, excessive Styana can lead to health imbalances and is often linked to conditions of excess Kapha dosha, emphasizing the need for activity and movement.
40) Pitta:
Pitta is one of the three doshas in Ayurveda, representing the elements of fire and water. It governs digestion and metabolism. An imbalance in Pitta can lead to various health issues, including inflammation and digestive disorders.
41) Manda (Mamda):
Manda refers to the quality of being slow or lethargic. In Ayurveda, Manda qualities can impact digestion and metabolism, contributing to conditions of imbalance, particularly when linked to Kapha dosha.
42) Nidradhikya (Nidra-adhikya):
Nidradhikya refers to excessive sleep or a state of fatigue beyond normal levels. This condition is often associated with Kapha dominance and indicates an imbalance requiring lifestyle adjustments to restore vitality and alertness.
43) Samprapti:
Samprapti describes the process of disease causation and progression in Ayurveda. Understanding Samprapti is essential for diagnosing the underlying factors of disease and implementing effective treatment strategies based on Ayurveda.
44) Prakopa:
Prakopa refers to the aggravation or exacerbation of doshas in Ayurveda. It is a critical stage in the progression toward disease, often requiring intervention to manage and restore balance.
45) Mamsa (Mamsha):
Mamsa is the muscle tissue in Ayurveda, associated with strength and body structure. Proper balance of Mamsa dhatu is crucial for physical health, and its deficiency or excess can lead to various health issues.
46) Matra:
Matra denotes the quantity or dosage of substances consumed or administered as per Ayurvedic principles. Proper Matra is essential for achieving desired therapeutic outcomes without adverse effects.
47) Vata:
Vata is one of the three doshas in Ayurveda, embodying the elements of air and space. It governs movement and communication in the body. An imbalance in Vata can lead to conditions like anxiety, dryness, and digestive issues.
48) Accumulation (Accumulating, Accumulate):
Accumulate refers to the gathering or buildup of substances in the body, often leading to pathological conditions. Managing the accumulation is essential for prevention and treatment of diseases.
49) Daurbalya:
Daurbalya signifies weakness or debility in Ayurveda. It can indicate an imbalance in doshas or dhatus, requiring therapeutic interventions to restore strength and vitality to the individual.
50) Samhita:
Samhita refers to classical texts of Ayurveda containing knowledge of medical practices, herbal formulations, and therapeutic methodologies. These texts serve as foundational knowledge for practitioners to diagnose and treat conditions.
51) Upalepa:
Upalepa denotes the application of medicinal pastes in Ayurveda, often used for local treatment of ailments and skin conditions. It emphasizes the therapeutic aspect of external herbal applications to restore balance.
52) Alasya:
Alasya indicates lethargy or lack of enthusiasm in Ayurveda. It is associated with imbalances in Kapha dosha and can lead to decreased motivation and productivity, requiring lifestyle adjustments for improvement.
53) Nidana:
Nidana refers to the causative factors or triggers of disease in Ayurveda. Recognizing Nidana is essential for effective diagnosis and treatment, as it guides practitioners toward addressing root causes.
54) Sanga (Samga, Shanga, Shamga):
Sanga represents the blockage or stagnation within bodily channels (srotas) in Ayurveda. It can lead to various health issues, particularly related to circulatory and metabolic disorders, requiring therapeutic strategies to clear blockages.
55) Diet:
Diet encompasses the food choices and eating patterns that impact health in Ayurveda. Proper diet plays a crucial role in maintaining balance among doshas and dhatus, preventing disease and promoting wellness.
56) Drug:
Drug refers to medicinal substances used in treatment according to Ayurvedic principles. The selection and application of herbs and formulations must consider individual constitution and specific health conditions to ensure efficacy.
57) Galaganda (Gala-ganda, Galagamda):
Galaganda refers to a disease in Ayurveda characterized by the enlargement of the thyroid gland (goiter), often linked to imbalances in Kapha and Rasa dhatu. Treatment focuses on restoring balance and addressing underlying causes.
58) Amasaya (Amashaya, Ama-ashaya):
Amashaya denotes the stomach in Ayurveda, considered the site of primary digestion. Understanding its function is vital for addressing digestive disorders and promoting overall health through dietary management.
59) Medicine:
Medicine encompasses the therapies and treatments utilized in Ayurveda to restore health. It combines the use of herbs, dietary practices, and lifestyle changes grounded in holistic health principles.
60) Tikshna (Tiksna):
Tikshna indicates sharpness or intensity in Ayurveda, commonly associated with strong digestive qualities. While beneficial for digestion, excess Tikshna can lead to conditions such as inflammation and irritation.
61) Channel:
Channel refers to the pathways in the body through which nutrients, blood, and energies flow. Proper functioning of channels is essential for maintaining health and preventing stagnation or blockages.
62) Water:
Water is essential for life and health in Ayurveda, considered one of the five great elements (Pancha Mahabhuta). Its quality and balance influence bodily functions, including digestion and hydration.
63) Sugar:
Sugar represents sweet substances in Ayurveda, playing a role in flavor and nutrient profile. While necessary in moderation, excessive sugar intake can lead to imbalances, contributing to conditions like diabetes.
64) Gati:
Gati denotes movement or flow within the body. Healthy Gati is essential for physiological processes, including circulation and digestion, whereas impaired Gati can lead to stagnation and disease.
65) Wall:
Wall refers to barriers or boundaries within the body, often in the context of anatomical structures that contain or support organs. Understanding these walls is essential for recognizing health issues related to pressure, flow, and integrity.
66) Inflammation:
Inflammation is the body's immune response to injury or infection, often causing redness and swelling. In Ayurveda, persistent inflammation indicates an underlying imbalance in doshas that requires therapeutic attention.
67) Raktadhatu (Rakta-dhatu):
Rakta-dhatu represents the blood dhatu in Ayurveda, vital for nourishment and oxygen transport. Its health impacts various physiological functions, and imbalances can lead to disorders like anemia.
68) Rukshata (Ruksata):
Rukshata denotes dryness in Ayurveda, which can affect bodily tissues and functions. Excess dryness is often linked to imbalances in Vata dosha and requires countermeasures to restore moisture and health.
69) Bhutagni (Bhuta-agni):
Bhutagni represents the elemental metabolic fire responsible for transforming the elements of food into usable energy. Its balance is essential for digestion and overall metabolic function.
70) Sukshma (Suksma, Shukshma):
Sukshma indicates subtle or minute aspects in Ayurveda. Understanding Sukshma is essential for addressing fundamental components of health and disease, emphasizing the intricate and interconnected nature of physiological processes.
71) Gaurava:
Gaurava refers to heaviness or a feeling of lethargy in Ayurveda. Often associated with Kapha imbalance, Gaurava can impact daily activities and overall energy levels, necessitating lifestyle adjustments.
72) Koshtha (Kostha):
Koshtha denotes the gastrointestinal tract in Ayurveda, playing a crucial role in digestion and assimilation of food. Understanding Koshtha aids in addressing digestive health and related disorders.
73) Prasara:
Prasara refers to the spread or dispersal of substances within the body in Ayurveda. Proper Prasara is crucial for maintaining physiological balance, ensuring even distribution of nutrients and energies.
74) Mandata:
Mandata signifies slowness or sluggishness in physiological processes. In Ayurveda, Mandata may signal metabolic disorders or digestive issues, often requiring interventions to boost energy and function.
75) Quality:
Quality in Ayurveda refers to the intrinsic characteristics or properties of substances, including food and medicines. Understanding the quality of these substances is essential for making informed choices for health and healing.
[Note: The above list is limited to 75. Total glossary definitions available: 241]