Invitro study on the anti - acne property of ayurvedic soap and body wash
Journal name: World Journal of Pharmaceutical Research
Original article title: Invitro study on the anti - acne property of ayurvedic soap and body wash
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Original source:
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Rekha N. and Anoop Austin
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Invitro study on the anti - acne property of ayurvedic soap and body wash
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr201717-10399
Download the PDF file of the original publication
Summary of article contents:
Introduction
The study investigates the anti-acne properties of two herbal cosmetic products, an Ayurvedic soap and a body wash, which contain a blend of 18 herbal ingredients. The research focused on their efficacy against Staphylococcus epidermidis, a bacterium commonly associated with acne development. The products were assessed at various points during their shelf lives to evaluate the persistence of their antibacterial effectiveness. The findings highlight that the soap demonstrated a greater and longer-lasting antimicrobial efficacy compared to the body wash, supporting the potential use of these herbal formulations as effective treatments for acne.
Efficacy of Herbal Ingredients in Acne Treatment
The primary objective of the study was to evaluate the antibacterial effects of the soap and body wash formulations. Consisting of 18 herbal actives, including Hemidesmus indicus, Azadirachta indica, and Commiphora wightii, the formulations exhibited significant inhibitory effects on Staphylococcus epidermidis. The soap maintained minimal inhibitory concentration (MIC) levels consistently at 2 mg/ml for up to 12 months before slightly declining towards the product's expiry. In contrast, the body wash showed a notable increase in MIC, reaching 20 mg/ml after 24 months, indicating a reduced effectiveness over time.
Stability and Performance Assessment
The study emphasized the importance of stability testing for these products. Samples were analyzed at regular intervals—initial, 3, 6, 9, 12, and 24 months—to monitor changes in their antimicrobial activity. The soap maintained its efficacy, while the body wash demonstrated declining effectiveness beyond 9 months, showcasing different stability profiles for the two formulations. This assessment is crucial for ensuring consistent therapeutic benefits to consumers.
The Role of Staphylococcus epidermidis
Staphylococcus epidermidis is recognized as a non-pathogenic bacterium that becomes opportunistically infectious, contributing to acne lesions. The research addressed the pathogenesis of acne, which involves a complex interaction of hormonal, bacterial, and immunological factors that expound the multifactorial nature of this skin disorder. Effective management of acne often involves antibiotics; however, the use of herbal remedies like those evaluated in this study represents a promising alternative that may reduce side effects associated with synthetic medications.
Conclusion
In conclusion, the investigation confirms the efficacy of Ayurvedic formulations, specifically the soap and body wash, against Staphylococcus epidermidis. The results indicate that while both products can serve as viable options for acne treatment, the soap exhibits superior and more prolonged antibacterial activity compared to the body wash. These findings contribute valuable insights into the utilization of herbal cosmetics for skincare, particularly in managing adolescent and young adult acne challenges. The study opens avenues for further research into improving the formulations and understanding their long-term effects.
FAQ section (important questions/answers):
What was the main focus of the study conducted by Austin et al.?
The study focused on evaluating the anti-acne properties of Ayurvedic soap and body wash containing 18 herbal ingredients against Staphylococcus epidermidis, assessing their efficacy over time.
What are the main herbal ingredients used in the formulations?
The formulations include 18 herbal actives such as Hemidesmus indicus, Zingiber zerumbet, Azadirachta indica, and Commiphora wightii, which have various antibacterial and anti-inflammatory properties beneficial for acne treatment.
How effective were the soap and body wash against acne?
The soap showed consistent effectiveness with a minimum inhibitory concentration (MIC) of 2 mg/ml over 12 months, while the body wash's efficacy decreased over time, reaching 20 mg/ml by 24 months.
What bacterial strain was targeted in the study?
The study specifically targeted Staphylococcus epidermidis, a gram-positive bacterium commonly associated with acne lesions and skin infections.
How was the effectiveness of the products measured in the study?
Effectiveness was measured through minimum inhibitory concentration (MIC) testing across various time intervals to assess the products' ability to inhibit bacterial growth.
What conclusion did the study draw about the Ayurvedic soap and body wash?
The study concluded that both the Ayurvedic soap and body wash are effective against Staphylococcus epidermidis, with the soap showing superior and more consistent results over time.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Invitro study on the anti - acne property of ayurvedic soap and body wash”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Study (Studying):
The keyword 'Study' refers to the systematic investigation undertaken to assess the anti-acne properties of Ayurvedic soap and body wash. It emphasizes the scientific approach used to test and evaluate the effectiveness and safety of the products, thereby contributing to credible evidence in herbal skincare formulations and their potential benefits against acne.
2) Drug:
The term 'Drug' is relevant as it signifies substances like antibiotics that are used to treat various conditions, including acne. The study highlights the exploration of herbal alternatives to synthetic drugs, emphasizing the importance of understanding both conventional pharmaceuticals and natural remedies in managing skin diseases.
3) Antibiotic (Antibacterial):
Antibiotic refers to substances that kill or inhibit the growth of bacteria. The study discusses the comparison between conventional antibiotics and herbal alternatives, addressing concerns over side effects associated with synthetic drugs while exploring natural options for treating acne.
4) Chennai:
Chennai, a major city in India, is the location of Cholayil Pvt Ltd., where the research was conducted. Its relevance lies in being the operational base for the study, linking local traditions of Ayurvedic medicine with modern scientific research methods in addressing skin care issues.
5) Disease:
The keyword 'Disease' relates to conditions like acne that affect individuals' skin health. The study investigates acne, a common dermatological issue, highlighting the importance of understanding its causes, treatments, and the role of herbal remedies in managing such diseases effectively.
6) Aureus:
Aureus, specifically Staphylococcus aureus, is a significant strain of bacteria linked to skin infections like acne. The term underscores the importance of studying bacterial interactions in acne pathology, focusing on combating harmful bacteria while promoting the efficacy of herbal formulations in skincare treatments.
7) Table:
The term 'Table' pertains to the representation of data in the study, summarizing findings, particularly the Minimum Inhibitory Concentration (MIC) results. Tables serve to present complex information clearly and concisely, allowing researchers and readers to compare results effectively across different time intervals and products.
8) Glycyrrhiza glabra:
Glycyrrhiza glabra, commonly known as licorice, is an herb noted for its anti-inflammatory and skin-soothing properties. The study references this plant due to its potential efficacy in treating acne, emphasizing the growing interest in natural ingredients within skincare and their therapeutic benefits.
9) Azadirachta indica:
Azadirachta indica, or neem, is renowned for its antibacterial and antifungal properties. Its inclusion in the study underscores its significance in traditional medicine and as a natural treatment option for acne, supporting the efficacy of herbal formulations against skin issues.
10) Commiphora wightii:
Commiphora wightii, commonly known as Guggulu, is highlighted for its traditional use in treating inflammatory conditions, including acne. This keyword emphasizes the relevance of ancient Ayurvedic practices and the potential for herbal remedies to address modern dermatological concerns effectively.
11) Cuminum cyminum:
Cuminum cyminum, or cumin, is recognized for its antimicrobial properties. The study's mention of this herb reflects the investigative nature of the research into the efficacy of various herbal ingredients in skincare products, particularly regarding their role in managing acne.
12) Vetiveria zizanioides:
Vetiveria zizanioides, known as vetiver, is praised for its antiseptic and skin-balancing qualities. Its examination in the study highlights the potential benefits of using traditional herbs in cosmetics, particularly for treating acne-prone skin, reinforcing the value of herbal solutions.
13) Acorus calamus:
Acorus calamus, or sweet flag, has been traditionally used for various medicinal purposes, including skin health. Its mention in the study serves to highlight its antimicrobial and anti-inflammatory effects as a valuable component in herbal formulations targeting acne treatment.
14) Embelia ribes:
Embelia ribes possesses antibacterial and antioxidant properties, making it a noteworthy ingredient in the study. Its relevance lies in the exploration of its effectiveness in protecting the skin and combating acne, thus enhancing the appeal of herbal skincare products.
15) Ambattur:
Ambattur is an area in Chennai, India, where Cholayil Pvt Ltd.'s Research and Development Centre is located. Its significance in the study lies in the local context of Ayurvedic product development, linking regional practices with modern scientific research in skincare.
16) India:
India is the country of interest as it is the origin of Ayurveda, the traditional system of medicine under investigation in the study. This context emphasizes the rich heritage of herbal treatments and the increasing validation of these practices through scientific research.
17) Cina:
China is mentioned in the study likely in relation to herbal medicine and traditional remedies. Its relevance captures the broader context of utilizing ancient knowledge and comparative research in herbal cosmetics, reflecting on global practices in skincare.
18) Road:
The term 'Road' in this context may refer to the physical location mentioned in the address of Cholayil Pvt Ltd. It signifies the geographical aspect of the study, marking a specific site where significant research and development efforts in herbal skincare occur.
19) Life:
Life pertains to the quality of existence affected by skin conditions like acne. The study underscores how such dermatological issues can lead to psychological impacts, illustrating the need for effective treatments to improve individuals' well-being and quality of life.
20) Berberis aristata:
Berberis aristata, with known antibacterial properties, plays a significant role in the study. Its inclusion as a herbal active emphasizes the potential efficacy of various plant extracts in acne treatments, aligning with the study's goal of exploring natural alternatives.
21) Observation:
Observation denotes the systematic recording and analysis of data obtained during experiments. The term highlights the scientific rigor of the study, as observations lead to valid conclusions regarding the effectiveness of herbal formulations against acne-causing bacteria.
22) Discussion:
Discussion refers to the interpretative segment where study findings are analyzed and implications are drawn. It emphasizes the importance of contextualizing results within existing literature, facilitating deeper understanding of the influence of herbal ingredients on acne treatments.
23) Quality:
Quality pertains to the standard of the herbal products studied in terms of their efficacy and safety. The term is relevant as the study evaluates product performance over time, ensuring that consumers receive effective natural remedies for acne management.
24) Weeping:
Weeping relates to open sores or lesions often seen in severe acne cases, emphasizing the importance of treating such symptoms. The study addresses the need for therapeutic products that not only manage acne but also promote healing of the affected skin.
25) Nature:
Nature refers to the inherent characteristics of the herbal ingredients investigated in the study. Understanding the nature of these components is crucial for determining their therapeutic potential in treating acne and contributing to holistic skincare solutions.
26) Rekha:
Rekha N. is one of the authors of the study, indicating her role in conducting the research. Her contribution signifies the collaborative nature of scientific exploration, underscoring the importance of diverse expertise in advancing understanding of herbal dermatological products.
27) Hair:
Hair relates to the pilosebaceous units affected in acne, emphasizing the complex interplay between hair follicles and oil glands in skin health. Understanding the relationship between hair, skin, and acne pathogenesis is vital for developing effective treatments.
28) Wall:
Wall may refer to the cellular walls that can be compromised in skin pores, allowing bacteria to proliferate, contributing to acne development. This keyword highlights the importance of understanding the biological mechanisms of acne for effective treatment solutions.
29) Line:
Line pertains to the correlation drawn between different studies or theories in the discussion, denoting continuity and progress in research. It emphasizes the importance of building upon existing knowledge to further develop effective acne treatments and herbal formulations.