Study on "Rajah Pravartini Vati" for primary dysmenorrhea efficacy.
Journal name: World Journal of Pharmaceutical Research
Original article title: A clinical study to evaluate efficacy of “rajah pravartini vati” on kashtartava w.s.r to primary dysmenorrhoea
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
This page presents a generated summary with additional references; See source (below) for actual content.
Summary of article contents:
Introduction
Dysmenorrhoea is a prevalent gynecological disorder affecting many women, particularly during adolescence, leading to significant discomfort and anxiety. This condition often results in emotional distress, impacting daily activities such as work, sports, and school. Current medical treatments include oral contraceptives and non-steroidal anti-inflammatory drugs, which can cause undesirable side effects with long-term use. Consequently, research into safe and effective Ayurvedic remedies is essential. This study focuses on “Rajah Pravartini Vati,” which is believed to address the symptoms of primary dysmenorrhea, also referred to as "Kashtartava," with a specific emphasis on its relationship with "Vata Dosha."
Efficacy of Rajah Pravartini Vati in Treating Kashtartava
The clinical trial evaluated the efficacy of Rajah Pravartini Vati for managing Kashtartava by analyzing its therapeutic impact on patients diagnosed with primary dysmenorrhea. The study included 25 participants who underwent treatment, with assessments focused on improvement in subjective symptoms. The findings revealed that after treatment, there was a notable reduction in pain intensity, duration, and the nature of pain experienced by the patients. Specifically, results indicated significant improvements, suggesting that Rajah Pravartini Vati could effectively alleviate the main complaints associated with dysmenorrhea.
Associated Symptoms and Overall Improvement
In addition to pain relief, the study also examined the impact of Rajah Pravartini Vati on various associated symptoms of dysmenorrhea, such as nausea, vomiting, fatigue, and headaches. The data demonstrated substantial improvements in these areas, showcasing the comprehensive benefits of the herbal formulation. Notably, the most remarkable results were noted in the alleviation of nausea and sweating, indicating the formulation's effectiveness in treating several discomforts commonly associated with dysmenorrhea. Statistically significant reductions in associated symptoms reinforce the potential of Rajah Pravartini Vati as a broad-spectrum remedy.
Patient Compliance and Safety
The safety and tolerability of Rajah Pravartini Vati were also evaluated throughout the study. The results showed that patients reported no significant side effects or toxicities, suggesting that the Ayurvedic treatment is gentle and suitable for long-term use without deleterious impacts on health. This aspect of the study is particularly relevant given the concerns surrounding the long-term use of conventional medications for primary dysmenorrhea, which often come with substantial side effects.
Conclusion
The findings of this clinical study underscore the efficacy and safety of Rajah Pravartini Vati in managing Kashtartava, or primary dysmenorrhea. Patients displayed marked improvements across various parameters, including pain intensity and associated symptoms, without experiencing adverse effects. Thus, Rajah Pravartini Vati emerges as a viable and effective alternative treatment for dysmenorrhea within the realm of Ayurvedic practices, warranting further research to validate these benefits and explore its broader applications in gynecological health.
Original source:
This page is merely a summary which is automatically generated hence you should visit the source to read the original article which includes the author, publication date, notes and references.
Dr.Diksha Khathuria, Dr.Vaibhav.P.Khirodkar, Dr.Khushwant Joshi, Dr.B.Pushpalatha and Dr. Sushila Sharma
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: A clinical study to evaluate efficacy of “rajah pravartini vati” on kashtartava w.s.r to primary dysmenorrhoea
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
FAQ section (important questions/answers):
What is the main focus of the clinical study?
The clinical study primarily focuses on evaluating the efficacy of 'Rajah Pravartini Vati' in treating primary dysmenorrhoea, also known as 'Kashtartava', which causes pain and discomfort during menstruation.
How is dysmenorrhoea commonly treated in modern medicine?
In modern medicine, dysmenorrhoea is typically treated with oral contraceptive pills, non-steroidal anti-inflammatory drugs, analgesics, and antispasmodics, which can have various side effects with long-term use.
Why is there a need for Ayurvedic treatment for dysmenorrhoea?
There is a need for Ayurvedic treatment to provide safe, effective, and cost-efficient remedies that do not cause the significant side effects associated with conventional medicines for dysmenorrhoea.
What constitutes the study's inclusion criteria for participants?
The study included participants aged 16 to 30 presenting with primary dysmenorrhoea for over two consecutive cycles and who had a history of using analgesics during menstruation.
What were the results regarding symptom improvement after treatment?
The results demonstrated significant improvements in pain intensity, pain duration, and associated symptoms, showing that 'Rajah Pravartini Vati' is an effective remedy for managing dysmenorrhoea.
How did the participants react to 'Rajah Pravartini Vati' during the study?
Participants responded positively to 'Rajah Pravartini Vati', experiencing relief from symptoms without reporting any side effects or toxic effects during the study.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Study on "Rajah Pravartini Vati" for primary dysmenorrhea efficacy.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Pain:
Pain is the primary symptom of dysmenorrhoea (Kashtartava), characterized by discomfort during menstruation. It significantly affects the quality of life for many women, impacting their ability to engage in daily activities, school, and work. Understanding pain is crucial for developing effective treatments and management strategies in both modern and traditional medicine.
2) Kashtartava (Kastartava, Kashta-artava):
Kastartava is synonymous with dysmenorrhoea in the study, indicating painful menstruation specific to primary cases. It serves as the primary focus of research, emphasizing the need for effective solutions and the role of Ayurvedic formulations in managing this common condition.
3) Vati:
Vati refers to a specific Ayurvedic formulation or dosage form, typically in the shape of small pills or tablets. These formulations are designed to encapsulate herbs and other ingredients for enhanced effectiveness. In the context of this study, Rajah Pravartini Vati is used for treating Kashtartava, demonstrating its relevance in traditional medicine.
4) Study (Studying):
The study refers to the clinical research conducted to evaluate the efficacy of Rajah Pravartini Vati in the management of Kashtartava (primary dysmenorrhoea). It follows scientific methods including assessments of symptoms, statistical analysis, and collection of data to draw conclusions. The relevance of the study lies in its potential to validate Ayurvedic treatments.
5) Drug:
Drug in this context refers to Rajah Pravartini Vati, the substance being studied for its therapeutic effects on dysmenorrhoea. Ayurvedic drugs are formulated using various herbs and ingredients, and understanding their pharmacological properties is essential for validating their use in treating conditions like Kashtartava.
6) Dysmenorrhea (Dysmenorrhoea):
Dysmenorrhea is synonymous with Kashtartava, representing painful menstrual periods. Its significance in the study underscores the desire to find effective, traditional remedies for this common condition affecting many women, aligning with the broader goal of improving reproductive health through safe Ayurvedic practices.
7) Diksa (Diksha):
Diksha is the lead author of the study, highlighting her role in contributing to Ayurvedic research. As a P.G. Scholar, her involvement underscores the importance of academic inquiry in traditional medicine. Her work aims to bridge the gap between ancient practices and modern scientific validation.
8) Jaipur:
Jaipur is the location of the National Institute of Ayurveda (NIA), where the clinical trial was conducted. The place is significant as it is a center for Ayurvedic research and education in India, promoting the study and validation of traditional medicine practices.
9) Vata:
Vata is one of the three doshas in Ayurveda representing the elements of air and space. It is associated with movement and governs various bodily functions. In the study, the condition Kashtartava is linked to Vata imbalance, thus understanding Vata is crucial for effective treatment.
10) Prasuti:
Prasuti refers to the Ayurvedic branch that focuses on obstetrics and gynecology. It is relevant in understanding women's health issues, including dysmenorrhoea. By delving into Prasuti, traditional practices can be evaluated and modified to better address conditions like Kashtartava.
11) Kumari:
Kumari, or Aloe vera, is one of the key ingredients in Rajah Pravartini Vati. This plant is known for its bitter taste and is used in Ayurveda for various therapeutic properties. Its inclusion in the formulation underscores the relevance of plant-based remedies in treating menstrual disorders.
12) Hingu (Himgu):
Hingu, or Ferula asafoetida, is an essential herb used in the study for treating dysmenorrhoea. Known for its carminative properties, it helps relieve abdominal pain and discomfort. Understanding Hingu’s pharmacological effects contributes to validating Ayurvedic treatments for conditions like Kashtartava.
13) Roga:
Roga translates to 'disease' in Ayurveda and is central to the study's focus on dysmenorrhoea. Understanding Roga involves examining disease symptoms, causes, and treatments, which is vital for the effective management of Kashtartava and other health issues in women.
14) Blood:
Blood is crucial in Ayurveda, associated with the Rakta dhatu (blood tissue) and its role in menstrual health. The study examines how improving blood circulation can alleviate symptoms of dysmenorrhoea, demonstrating the interconnectedness of bodily systems in Ayurvedic treatment approaches.
15) Kashi (Kasi):
Kasi is another key ingredient in Rajah Pravartini Vati. Its role in promoting uterine health and blood circulation is essential for addressing dysmenorrhoea. The study highlights how combining different herbs can enhance the therapeutic impact of Ayurvedic formulations.
16) Vatadosha (Vatadosa, Vata-dosha):
Vata-dosha is a fundamental concept in Ayurveda, representing the energetic forces within the body. Imbalances in Vata-dosha are believed to contribute to conditions like Kashtartava. Addressing this imbalance is crucial for effective treatment and emphasizes the need for tailored Ayurvedic interventions.
17) Suffering:
Suffering refers to the physical and emotional distress experienced by women with dysmenorrhoea. Its relevance is intertwined with the study's aim to alleviate pain and discomfort through safe Ayurvedic remedies, highlighting the importance of addressing both physical and psychological aspects of health.
18) Ayurveda (Ayus-veda):
Ayurveda is a traditional system of medicine originated in India, emphasizing balance and holistic health. This study aims to validate Ayurvedic remedies for dysmenorrhoea, reinforcing the significance of ancient knowledge in modern health care practices and offering alternative treatments to conventional medicine.
19) Tankana (Tamkana):
Tankana is another herb included in Rajah Pravartini Vati, known for its properties that enhance uterine health. It plays a vital role in relieving symptoms of dysmenorrhoea by improving uterine function and tonicity, thus contributing to the therapeutic efficacy of the formulation in the study.
20) Disease:
Disease refers to a pathological condition affecting normal bodily functions. The relevance of understanding disease within this study lies in the exploration of dysmenorrhoea as a common disorder, emphasizing the need for effective treatment strategies to improve women's health and quality of life.
21) Bitter:
Bitter is a taste associated with certain Ayurvedic herbs, including Kumari. Bitterness can stimulate digestive enzymes and promote overall health. In the context of this study, identifying bitter herbs helps in understanding their role in harmonizing the body’s doshas and improving symptoms of dysmenorrhoea.
22) Nature:
Nature signifies the inherent characteristics of substances, including their effects on the body. The study assesses the nature of Rajah Pravartini Vati's ingredients, which encompass various properties crucial for alleviating dysmenorrhoea symptoms, emphasizing the importance of natural treatments in holistic health.
23) Dosha (Dosa):
Dosha refers to the three primary energies that govern physical and mental processes in Ayurveda. Balancing doshas is critical for maintaining health. This study explores how imbalances in Vata dosha contribute to Kashtartava, guiding effective treatment strategies using Ayurvedic principles.
24) Table:
Table refers to the data presentation format used in the study to illustrate findings and results. This organization of data is essential for analyzing the efficacy of treatments, facilitating comparison, and ensuring clarity for readers regarding the study's outcomes and statistical significance.
25) Katu:
Katu, meaning pungent, describes a taste associated with certain Ayurvedic herbs. It is believed to have stimulating properties that can aid digestion and circulation. Understanding Katu's role helps elucidate how specific tastes and their herbs can contribute to treating conditions like dysmenorrhoea.
26) Bhaishajya (Bhaisajya):
Bhaishajya translates to 'medicine' in Ayurveda, indicating the therapeutic formulations derived from herbal ingredients. The study focuses on validating the effectiveness of a specific medicine, Rajah Pravartini Vati, demonstrating the ongoing relevance of traditional medicinal practices in addressing conditions like dysmenorrhoea.
27) Medicine:
Medicine refers to herbs and formulations used to treat diseases. In this study, medicine represents Rajah Pravartini Vati, highlighting the exploration of its therapeutic potential in managing dysmenorrhoea, demonstrating the importance of traditional systems in contemporary health care settings.
28) Vomiting:
Vomiting is one of the associated symptoms of dysmenorrhoea, impacting the quality of life. In the context of this study, it serves as a parameter to evaluate the therapeutic effects of Rajah Pravartini Vati, emphasizing the need to address all symptoms related to dysmenorrhoea.
29) Fainting (Fainted):
Fainting can occur as a secondary symptom of severe dysmenorrhoea, reflecting the condition's impact on overall wellbeing. The study considers fainting among the symptoms to assess the efficacy of the Ayurvedic remedy being tested, highlighting the comprehensive approach of managing dysmenorrhoea.
30) Tikshna (Tiksna):
Tikshna, meaning sharp, refers to the potent qualities of certain Ayurvedic herbs. This concept is relevant as it describes the efficacy of Rajah Pravartini Vati, which possesses properties that can alleviate pain and discomfort associated with dysmenorrhoea through its sharp and penetrating actions.
31) Artava:
Artava refers to menstrual blood in Ayurveda, associated with women's health. Understanding Artava is significant as it connects the physiological aspects of menstruation with treatments aimed at restoring balance and relieving dysmenorrhoea, underscoring the focus of the study on reproductive health.
32) Vipaka:
Vipaka pertains to the post-digestive effect of food and herbs in Ayurveda. It is relevant for understanding how the ingredients in Rajah Pravartini Vati influence the body after consumption, contributing to the formulation's overall effectiveness in treating dysmenorrhoea.
33) Nausea:
Nausea is a common symptom experienced during menstrual discomfort. Evaluating its presence in the study allows for a comprehensive understanding of patients' experiences with dysmenorrhoea and provides insight into the efficacy of Rajah Pravartini Vati as a potential remedy.
34) Tikta:
Tikta translates to 'bitter' in Ayurveda, describing a flavor profile of certain healing herbs. The taste is believed to have therapeutic attributes that aid digestion and reduce inflammation. Its role in the formulation highlights the significance of taste in Ayurvedic medicine for effective treatments.
35) Ushna (Usna):
Ushna, meaning 'hot' or 'warming,' describes certain herbs' quality that can stimulate digestion and promote circulation. In the context of this study, understanding Ushna's role helps explain how Rajah Pravartini Vati addresses symptoms of dysmenorrhoea through its warming effects on the body.
36) Virya:
Virya refers to the potency or strength of an herbal substance in Ayurveda. It is crucial for assessing the effectiveness of Rajah Pravartini Vati in treating dysmenorrhoea. Understanding virya helps practitioners identify appropriate herbs for specific conditions and enhance treatment efficacy.
37) Sweating (Sweat):
Sweat is a physical response that might occur during dysmenorrhoea due to pain or discomfort. Evaluating changes in sweating as a symptom of dysmenorrhoea can provide insights into the effectiveness of treatment with Rajah Pravartini Vati, contributing to a holistic understanding of patient experiences.
38) Ferula asafoetida (Ferula assa-foetida):
Ferula asafoetida, commonly known as Hingu, is a significant herb used in traditional medicine for its digestive properties. Its inclusion in Ayurvedic formulations like Rajah Pravartini Vati highlights its relevance in managing gastrointestinal symptoms associated with dysmenorrhoea, thus fostering holistic treatment approaches.
39) Artavajanana:
Artavajanana refers to substances that promote menstrual health and regularity in Ayurveda. The focus on Artavajanana in the study underscores the importance of maintaining menstrual health for improving women's quality of life and the efficacy of the herbal treatments being tested.
40) Raktadhatu (Rakta-dhatu):
Rakta-dhatu refers to the blood tissue in Ayurveda, playing a crucial role in women's health, particularly during menstruation. Enhancing Rakta-dhatu circulation is essential for alleviating symptoms of dysmenorrhoea, making it a relevant focus in the effectiveness of Rajah Pravartini Vati.
41) Garbhashaya (Garbhasaya, Garbha-ashaya):
Garbhashaya refers to the uterus in Ayurveda. Understanding its role is essential when studying women's health issues, as it connects physical health to reproductive functions. Effective treatments for dysmenorrhoea must consider the health of the Garbhashaya.
42) Observation:
Observation refers to the process of monitoring symptoms and treatment outcomes in the clinical study. It's a crucial element for assessing the effectiveness of Rajah Pravartini Vati, enabling researchers to draw meaningful conclusions regarding the therapeutic potential of Ayurvedic medicine.
43) Asafoetida:
Asafoetida, known as Hingu, is an important herb in the study, renowned for its colic pain-relieving properties. Surgical evaluations show its effectiveness in alleviating symptoms associated with dysmenorrhoea, highlighting its relevance as part of the Ayurvedic treatment regimen.
44) Discussion:
Discussion refers to the section of the study where findings and interpretation of results are analyzed. It contextualizes the significance of the data collected, helping to establish the efficacy of Rajah Pravartini Vati while drawing connections to broader Ayurvedic practices and modern health paradigms.
45) Depression:
Depression can be an emotional response resulting from chronic pain, including dysmenorrhoea. Addressing the psychological impact of painful periods is crucial for a holistic treatment approach in the study, highlighting the interplay between mental and physical health in women's wellness.
46) Madhyama:
Madhyama translates to 'middle' or 'medium' and often denotes an intermediate state in various Ayurvedic classifications. Its relevance may manifest in the study when discussing the balance of therapies, effects, and grading symptoms, providing a framework for treatment strategies based on individual needs.
47) Rasayana (Rasa-ayana):
Rasayana refers to rejuvenating therapies in Ayurveda aimed at promoting longevity and vitality. It is relevant in the study as treatments may aim not only to alleviate symptoms of dysmenorrhoea but also to enhance overall health and wellness in women.
48) Activity:
Activity encompasses actions and functions of the body, particularly in relation to the menstrual cycle. Understanding bodily activity provides context for the impact of dysmenorrhoea and the role of treatments in restoring normal physiological functions enhances the study's relevance.
49) Samhita:
Samhita refers to ancient Ayurvedic texts containing knowledge about formulations and treatments. Its relevance lies in providing the foundational principles from which modern practices derive, ensuring that contemporary studies remain rooted in traditional wisdom while seeking to validate efficacy scientifically.
50) Kalpana:
Kalpana denotes the preparation methods of Ayurvedic formulations. In the study, understanding Kalpana is essential as it details how Rajah Pravartini Vati is prepared and its implications for ensuring the proper delivery of herbs, enhancing efficacy for treating dysmenorrhoea.
51) Udaipur (Udaypur):
Udaipur is mentioned as the location of one of the contributors in the study. Its significance reflects the broader regional practices of Ayurveda and educational institutions that contribute to the field, reinforcing the collaborative nature of research in traditional medicine.
52) Vriddhi (Vrddhi):
Vriddhi translates to 'growth' or 'increase' in Ayurveda, often referring to the enhancement of bodily functions or tissues. In the study, understanding Vriddhi helps contextualize how treatments aim to restore and improve health conditions, particularly concerning women's reproductive health.
53) Pungent:
Pungent describes a taste associated with certain herbs, indicative of their potential medicinal properties. It is relevant as it signifies certain characteristics that can stimulate digestion and circulation, highlighting how taste influences the selection of herbs used in treating dysmenorrhoea.
54) Anxiety:
Anxiety is an emotional symptom often accompanying physical pain and discomfort, like that experienced in dysmenorrhoea. Its relevance within the study emphasizes the need for holistic approaches in treatment, considering physical relief alongside emotional well-being for improved patient outcomes.
55) Vertigo:
Vertigo indicates a sensation of spinning or dizziness, sometimes experienced during severe pain episodes. Recognizing vertigo as part of the symptomatology of dysmenorrhoea allows researchers to understand the full impact of menstrual pain and the need for comprehensive management strategies.
56) Vikara:
Vikara refers to any disorder or pathology in Ayurveda, encapsulating the concept of disease. In the study, it highlights the focus on understanding and treating dysmenorrhoea (Kashtartava) as a disorder to establish effective Ayurvedic remedies.
57) Tankan:
Tankan is a herb mentioned in the formulation Rajah Pravartini Vati. Its relevance rests in its properties that support women's health, particularly concerning uterine function and menstrual regularity, emphasizing the importance of herbal ingredients in managing dysmenorrhoea.
58) Sharman (Sarma, Sharma, Sarman):
Sharma is one of the authors of the study, contributing to the collective expertise and research efforts in exploring Ayurvedic formulations. The collaboration of various authors reflects a multidisciplinary approach in modernizing traditional medicine through scientific methods.
59) Khanda (Khamda):
Khanda refers to a section or part in ancient Ayurvedic texts. Its relevance in the study might relate to the sourcing of traditional knowledge and practices which guide the formulation and understanding of treatments like Rajah Pravartini Vati.
60) Laghu:
Laghu translates to 'light' in Ayurvedic terms, indicating substances that are easy to digest. In the study, the concept of Laghu represents the importance of selecting herbs that facilitate digestion and absorption, which can be beneficial in treating dysmenorrhoea effectively.
61) Rakta:
Rakta refers to 'blood' in Ayurveda, highlighting its critical role in overall health and particularly in reproductive health. The study focuses on how enhancing Rakta circulation can alleviate symptoms of dysmenorrhoea, linking blood health to women's well-being.
62) Dhatu:
Dhatu translates to 'tissue' or 'substance' in Ayurveda, crucial for understanding how different body systems function. In this study, the focus on different Dhatu types—particularly Rakta—contributes to a comprehensive model for treating conditions like dysmenorrhoea.
63) Joshi (Josi):
Joshi is another contributor to the study, highlighting the collaborative aspect of research in Ayurveda. His participation underscores the importance of shared expertise in validating traditional remedies and broadening the scientific understanding of conditions affecting women's health.
64) Balya:
Balya translates to 'strength-promoting' in Ayurveda, indicating substances that enhance health and vitality. The relevance of Balya in this context lies in the study's goal of not just treating dysmenorrhoea but also supporting overall health and resilience in patients.
65) House:
House refers to the familial and domestic context in which women experience dysmenorrhoea. Understanding the impact of home environments on health can provide insight into social factors affecting women's experiences with conditions like Kashtartava.
66) Raja:
Raja refers to 'menstrual fluid' in Ayurveda and is central to the discussion of women's health. Its importance in the study emphasizes the physiological aspects of menstruation, aiding in the understanding of dysmenorrhoea and the relevance of treatments targeting menstrual health.
67) Kaya:
Kaya translates to 'body' in Ayurveda, referring to the physical being and its health as influenced by various factors including diet, lifestyle, and treatment modalities. In the study, exploring body health connects directly to the management of dysmenorrhoea.
68) Rasa (Rasha):
Rasa translates to 'taste' in Ayurveda, marking its significance in the effects of food and herbs on the body. The concept of Rasa is essential in evaluating the therapeutic properties of the ingredients in Rajah Pravartini Vati_used to treat dysmenorrhoea.
69) Vayu:
Vayu refers to the air element in Ayurveda, representing one of the three doshas (Vata, Pitta, Kapha) responsible for bodily movements and functions. The study highlights its importance in relation to dysmenorrhoea, particularly in understanding how Vata imbalances can lead to menstrual ailments.
70) Guna:
Guna translates to 'quality' in Ayurveda, describing the inherent characteristics of substances. Understanding Guna aids in selecting effective herbal ingredients for formulations, crucial in the study assessing Rajah Pravartini Vati for managing dysmenorrhoea effectively.
71) Diet:
Diet plays an essential role in Ayurveda, as it influences overall health and balance in the body. In the context of the study, analyzing the dietary habits of participants may provide insights into lifestyle factors affecting dysmenorrhoea and can help in formulating comprehensive treatment plans.
72) Sign:
Sign refers to observable indicators of health conditions, such as symptoms of kashtartava. In the study, understanding various signs is essential for assessing the efficacy of Rajah Pravartini Vati and the overall impact of the treatment on patients.
73) Life:
Life encompasses the holistic experience of individuals, including physical, mental, and emotional health. The study's focus on dysmenorrhoea reflects the importance of improving not only women's reproductive health but also enhancing their overall quality of life through effective Ayurvedic treatments.