Antidiarrheal effects of Manihot esculenta leaf extract in rats

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Journal name: Journal of Ayurveda and Integrative Medicine
Original article title: Antidiarrheal activity of ethanolic extract of Manihot esculenta Crantz leaves in Wistar rats
The Journal of Ayurveda and Integrative Medicine (JAIM) is an open-access publication promoting collaboration between Ayurveda, traditional medicine, and biomedicine, publishing research on integrative health sciences
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Original source:

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Author:

Satish E. Bahekar, Ranjana S. Kale


Journal of Ayurveda and Integrative Medicine:

(A monthly peer-reviewed publication)

Full text available for: Antidiarrheal activity of ethanolic extract of Manihot esculenta Crantz leaves in Wistar rats

Year: 2015 | Doi: 10.4103/0975-9476.146542

Copyright (license): CC BY-NC-ND 4.0


Download the PDF file of the original publication


Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Antidiarrheal effects of Manihot esculenta leaf extract in rats”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Drug:
The term 'Drug' in this context refers to substances used to prevent, diagnose, or treat health conditions. In the study, standard drugs such as loperamide and atropine sulfate were administered to Wistar rats to compare their antidiarrheal effects with that of the ethanolic leaf extract of Manihot esculenta Crantz, highlighting the importance of pharmacological research in developing effective treatments for diarrhea.

2) Food:
Food is a crucial element in the context of the Manihot esculenta Crantz plant, commonly known as tapioca. It serves as a staple food for millions in developing countries, emphasizing the plant's significance in ensuring food security. The dual role of MEC as a source of nourishment and potential medicinal remedy underlines its importance in both food science and dietary health.

3) Crop:
The classification of Manihot esculenta Crantz as a 'Crop' illustrates its agricultural importance. Crops are cultivated plants harvested for food, fiber, or other economic purposes. The cultivation of tapioca contributes significantly to the livelihoods of farmers and plays a vital role in food production systems, particularly in regions where food security is a critical issue.

4) Accumulation (Accumulating, Accumulate):
The word 'Accumulation' in this context refers to the build-up of intestinal fluid as induced by castor oil in the study. This model assesses the effectiveness of antidiarrheal agents by measuring the reduction of excess fluid in the intestines, thereby providing insights on how the MEC extract can mitigate symptoms of diarrhea.

5) Agriculture:
Agriculture encompasses the cultivation of plants and livestock for food production, which is essential for human survival. The mention of MEC within agricultural literature emphasizes its role not just as a food source but also as a crop with medicinal properties. It underscores the intersection of agriculture, nutrition, and health in global food systems.

6) Developing:
The term 'Developing' pertains to countries or regions that are in the process of economic growth and often face challenges like food insecurity. MEC is particularly significant for these areas, as it provides a source of food and potential medicinal benefits, addressing both nutritional and health needs in populations with limited resources.

7) Science (Scientific):
The term 'Scientific' underscores the reliance on empirical research and evidence in validating traditional uses of plants like MEC. The study aims to fill gaps in existing literature by providing rigorous scientific investigation into the antidiarrheal properties of the plant extract, thereby contributing to the body of knowledge in pharmacology and traditional medicine.

8) Activity:
The word 'Activity' signifies the functional properties of the ethanolic leaf extract of MEC, specifically its antidiarrheal effects. The activity of a substance is critical in pharmacology; understanding how MEC influences physiological processes can lead to the development of effective treatments and enhance our comprehension of plant-based therapies in modern medicine.

9) Castor:
In this context, 'Castor' refers to castor oil, a substance used to induce diarrhea in experimental models. This method is employed to evaluate the effectiveness of the MEC extract against intestinal fluid accumulation. The use of castor oil represents a standard practice in pharmacological research to assess therapeutic interventions.

10) India:
India’s mention reflects the geographical and cultural significance of MEC, as it is commonly utilized in dietary practices within the country. The relevance of the plant in India's agricultural landscape and its potential health benefits make it a topic of interest, highlighting the intersection of traditional knowledge and modern scientific validation.

11) Study (Studying):
The term 'Study' signifies the systematic investigation undertaken to evaluate the antidiarrheal activity of MEC. It involves experimental methodologies and data analysis to draw conclusions about the efficacy of the plant extract. The study's findings contribute to broader discussions on the therapeutic potential of traditionally used plants in enhancing health outcomes.

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