Herbal extract gel efficacy in treating gingivitis: A clinical study
Journal name: Journal of Ayurveda and Integrative Medicine
Original article title: Efficacy of a herbal extract gel in the treatment of gingivitis: A clinical study
The Journal of Ayurveda and Integrative Medicine (JAIM) is an open-access publication promoting collaboration between Ayurveda, traditional medicine, and biomedicine, publishing research on integrative health sciences
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Original source:
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C. Ashwini Somu, S. Ravindra, Soumya Ajith, Mohammed Gulzar Ahamed
Journal of Ayurveda and Integrative Medicine:
(A monthly peer-reviewed publication)
Full text available for: Efficacy of a herbal extract gel in the treatment of gingivitis: A clinical study
Year: 2012 | Doi: 10.4103/0975-9476.96525
Copyright (license): CC BY-NC-ND 4.0
Download the PDF file of the original publication
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Herbal extract gel efficacy in treating gingivitis: A clinical study”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Pomegranate:
Pomegranate refers to the fruit of the tree Punica granatum, noted for its antibacterial and anti-inflammatory properties. In this study, it is utilized to assess its effectiveness in treating chronic gingivitis. Its extracts provide a natural alternative for oral care, reducing plaque and inflammation in gums.
2) Study (Studying):
The study represents a systematic investigation evaluating the effectiveness of a pomegranate extract gel on chronic gingivitis. Spread over 21 days with a randomized clinical trial design, it sought to compare clinical results and microbiological parameters across different treatment groups of patients.
3) Disease:
Disease in the context of this research refers specifically to chronic gingivitis, a common inflammatory condition affecting the gums, characterized by plaque buildup. The study aimed to address the challenges of conventional treatments for this disease, exploring natural alternatives such as pomegranate extract.
4) Antibiotic (Antibacterial):
Antibiotic refers to drugs typically used to treat bacterial infections, but their overuse can lead to resistance. This study explores the potential for using pomegranate extract as an effective alternative to antibiotics for managing bacterial loads in chronic gingivitis.
5) Activity:
Activity pertains to the functional effectiveness of the pomegranate gel, specifically its impact on reducing plaque formation and gingivitis severity. The study measures these activities through clinical indices and microbiological analysis, providing evidence of the gel's beneficial health effects when combined with mechanical debridement.
6) Bleeding:
Bleeding, particularly in the context of gingivitis, indicates inflammation of the gums. The study evaluated the papillary bleeding index (PBI) to measure bleeding responses in patients using the pomegranate gel, aiming to determine its efficacy in reducing gingival bleeding compared to control treatments.
7) Hygiene (Hygienic):
Hygiene is central to preventing periodontal diseases like gingivitis. This study underscores the importance of daily oral hygiene and how herbal adjuncts like pomegranate can support traditional mechanical methods, aiming to improve overall oral health outcomes and prevent disease progression.
8) Table:
Table structures serve as organizational tools in the study, summarizing clinical and microbiological results such as plaque index, gingival index, and bleeding scores. They facilitate easy comparison and analysis of data across different treatment groups, enabling clearer interpretation of the pomegranate gel's effects.
9) Visit:
Visit refers to the scheduled appointments where patients received gels, assessed clinical parameters, and collected plaque samples over the 21-day trial. These visits were crucial for monitoring patient progress and compliance, as well as for applying the treatments as directed during the study.
10) Performance:
Performance in the study context assesses the effectiveness of the pomegranate gel in improving gingivitis symptoms and plaque control. Clinical measures, including individual patient results and statistical analyses, evaluate how well the gel performs compared to control treatments over the trial duration.
11) Tree:
Tree refers to the pomegranate tree (Punica granatum), the source of the fruit utilized in this study. Its natural extracts are significant for their medicinal properties, particularly in traditional herbal medicine, offering insights into integrating botanical therapies into modern periodontal care.
12) Surface:
Surface relates to the oral surfaces where plaque accumulates, leading to gum disease. This study examines how the application of pomegranate gel affects plaque control on these surfaces, determining its effectiveness relative to treatment without mechanical debridement.
13) Animal:
Animal signifies that gingivitis and periodontal diseases can affect all dentate animals, emphasizing the widespread relevance of this study. Findings for human conditions potentially parallel treatments and therapies applicable to veterinary practices, expanding the study's implications beyond human dental care.
14) Field:
Field pertains to the microscopic examination conducted on plaque samples collected from patients. Analyzing bacteria in selected microscopic fields helps quantify the different types of organisms present, aiding in understanding the microbiological impact of treatment across the groups in this study.
15) Sign:
Sign denotes clinical symptoms, particularly gingival bleeding, used to evaluate the severity of gingivitis. In this research, clinical signs are quantified through indices, allowing for a standardized assessment of treatment effects similar to those seen in previous studies.
16) Drug:
Drug refers to conventional pharmaceutical treatments previously required to manage gingivitis. This study seeks to explore a natural alternative, pomegranate extract, which is proposed to provide therapeutic benefits without the side effects and complications typically associated with chemical drugs.
17) Punica granatum:
Punica granatum is the scientific name of the pomegranate tree, which hosts the fruit utilized in the study. This nomenclature highlights the significance of precise botanical identification in research, as the fruit's extracts contain various compounds with potential therapeutic applications for oral health.
18) Inflammation:
Inflammation is a key process in gingivitis where the body's immune response to plaque leads to gum swelling and bleeding. This study evaluates the anti-inflammatory effects of pomegranate gel, theorizing that its application may help reduce inflammatory markers in affected patients.
19) Developing:
Developing relates to the innovation and advancement of treatments for oral diseases such as gingivitis. This study contributes to the developing field of herbal medicine by assessing the efficacy of pomegranate gel as a potential adjunctive treatment alongside traditional mechanical therapy.
20) Karnataka (Karṇāṭaka):
Karnataka is the Indian state where the study was conducted, highlighting the specific geographic and cultural context of the research. This location provides a regional basis for understanding local health practices and the relevance of herbal treatments like pomegranate in periodontal care.
21) Inference:
Inference involves concluding results from collected data. In this study, inferences drawn from clinical and microbiological results help assess the efficacy of pomegranate gel, guiding interpretations relevant to its potential role in treating gingivitis and contributing to future research formulations.
22) Container:
Container refers to the small plastic jars used to deliver the pomegranate and control gels to patients during the study. Their design ensures proper usage and preservation of the gels, acting as an important logistical element in the trial's execution and patient compliance.
23) Ayurveda (Āyurveda, Ayus-veda):
Ayurveda refers to the traditional Indian system of medicine that has utilized pomegranate for its medicinal properties. The relevance in this study lies in bridging ancient herbal practices with modern clinical research, validating the effectiveness of these natural remedies in contemporary oral healthcare.
24) Medicine:
Medicine encompasses healing practices aimed at diagnosing and treating diseases. The study focuses on integrating natural herbal products, such as pomegranate extract, into the realms of modern dental medicine, assessing their place in treating prevalent conditions like gingivitis.
25) Pregnant:
Pregnant refers to women who are excluded from the study due to potential health risks associated with gingivitis treatments. This consideration ensures patient safety and compliance with ethical guidelines, emphasizing the need for careful participant selection in clinical research.
26) Habitat:
Habitat highlights the natural environment where various microbial species reside in the oral cavity. The study examines how pomegranate extract influences these habitats, particularly focusing on pathogenic bacteria as it aims to maintain balance while reducing disease-causing agents.
27) Species:
Species refers to specific bacterial types examined during the microbiological analysis of plaque samples. Understanding how various microbial species respond to treatments, particularly those altered by pomegranate gel, contributes to knowledge about the dynamics of oral microbiomes in gingivitis.
28) Aureus:
Aureus often refers to Staphylococcus aureus, a bacterium that studies have shown to have antimicrobial susceptibility to pomegranate extracts. The relevance of this species in the study relates to examining the broad-spectrum antibacterial properties of pomegranate against common oral pathogens.
29) Family:
Family in this context pertains to the classification of the pomegranate tree within the Punicaceae family. This classification aids in understanding the plant's biological characteristics and its therapeutic potential in relation to its medicinal use in the oral healthcare domain.
30) Nature:
Nature emphasizes the organic and non-synthetic aspects of pomegranate extract used in the study. By focusing on natural products, the research aligns itself with growing interests in holistic and less invasive treatments for managing oral health issues like gingivitis.
31) Misuse:
Misuse relates to the overuse of antibiotics and conventional drugs, leading to microbial resistance. The study advocates for exploring pomegranate as a therapeutic alternative to combat these concerns, presenting the extract as a safer option in the management of gingivitis.
32) India:
India denotes the country where the study was conducted, marking the cultural and geographical significance of the research. The investigation into a traditional herbal remedy like pomegranate aligns with India's rich history of using natural products for health and wellness.
33) Water:
Water is a crucial component in creating the gels used throughout the study. Adequate hydration ensures proper ingredient mixing and consistency in gel formulation, providing a stable medium for the effective delivery of pomegranate extracts to patients’ gums.
34) Edema (Oedema):
Edema refers to swelling often associated with inflammation in gum tissues during gingivitis. The study hints at the potential of pomegranate's anti-inflammatory properties to mitigate edema, consequently supporting healthier gingival conditions and enhancing overall patient treatment outcomes.
35) Fever:
Fever represents one of the conditions historically treated with pomegranate. Though not directly related to gingivitis, its mention in the study serves to underline the broad therapeutic applications of pomegranate in traditional and modern medicine beyond just oral health.
36) Asha (Āsā, Āsa, Asa, Asā, Āśā, Aśa, Āśa):
Asha signifies a contributor to previous research on the antibacterial effects of pomegranate. By referencing prior studies and findings, it contextualizes current research efforts within a larger framework of exploration into herbal therapies for oral health.
37) Male (Mālē):
Male indicates the gender distribution of the study's participants, with data showing a mix of male and female subjects. This demographic detail is crucial for understanding how treatment effects may vary based on gender and provides context for clinical interpretations.
38) Gold (Golden):
Gold symbolizes the standard of care in periodontal management, highlighting that mechanical debridement remains the foundational approach to treating gingivitis. The study evaluates how well pomegranate gel can serve as an adjunct to this gold standard in improving clinical outcomes.