Aquilaria crassna leaves extract: antipyretic, analgesic, antioxidant.
Journal name: Journal of Ayurveda and Integrative Medicine
Original article title: Antipyretic, analgesic and anti-oxidative activities of Aquilaria crassna leaves extract in rodents
The Journal of Ayurveda and Integrative Medicine (JAIM) is an open-access publication promoting collaboration between Ayurveda, traditional medicine, and biomedicine, publishing research on integrative health sciences
This page does not contain the article itself; See source (below) for actual content.
Original source:
This page only sums up technical details and meta-data hence you should visit the source to read the original article which includes the author, publication date, notes and references.
Jintana Sattayasai, Jirawat Bantadkit, Chantana Aromdee, Eric Lattmann, Wanchai Airarat
Journal of Ayurveda and Integrative Medicine:
(A monthly peer-reviewed publication)
Full text available for: Antipyretic, analgesic and anti-oxidative activities of Aquilaria crassna leaves extract in rodents
Year: 2012 | Doi: 10.4103/0975-9476.104427
Copyright (license): CC BY-NC-ND 4.0
Download the PDF file of the original publication
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Aquilaria crassna leaves extract: antipyretic, analgesic, antioxidant.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Animal:
The term 'Animal' refers to the species used in the study, specifically rodents, which are commonly utilized in pharmacological experiments due to their physiological and anatomical similarities to humans. The use of animals facilitates the investigation of biological processes and the efficacy of substances in living organisms, providing insights relevant to human health.
2) Activity:
In the context of the study, 'Activity' pertains to the functional effects exhibited by the aqueous extract of Aquilaria crassna leaves. Specifically, it references antipyretic, analgesic, anti-inflammatory, and anti-oxidative effects. Understanding the biological activities of herbal extracts is crucial for assessing their therapeutic potential and guiding their application in traditional medicine.
3) Water:
'Water' is used as a control substance in the experiments to compare the effects of the Aquilaria crassna leaves extract against a baseline. It is critical in scientific experiments as it serves to ensure that any observed effects in the test groups are due to the extract itself rather than other environmental factors.
4) Study (Studying):
'Study' indicates the organized investigation conducted to evaluate the pharmacological properties of Aquilaria crassna. This research is relevant for validating traditional uses and contributing to the scientific knowledge of herbal medicines, assessing their efficacy and safety through systematic experimentation that adheres to scientific methodologies.
5) Fever:
In this context, 'Fever' refers to the elevated body temperature induced experimentally in rats using Baker's yeast for the purpose of examining the antipyretic properties of the extract. Studying fever models is essential for understanding how potential treatments can mitigate hyperthermic responses, thereby supporting their therapeutic claims.
6) Pharmacological:
'Pharmacological' relates to the study of the effects and mechanisms of drugs and medicinal substances. In this research, it emphasizes the exploration of how Aquilaria crassna leaves extract interacts at a biological level, contributing to the understanding of its therapeutic properties and the potential for medical applications.
7) Science (Scientific):
'Science' embodies the systematic study of the structure and behavior of the physical and natural world through observation and experimentation. This research exemplifies the principles of science by applying rigorous methods to explore and validate the medicinal properties of a traditionally used herbal plant.
8) Medicine:
'Medicine' refers to the field concerned with health, healing, and the treatment of disease. The study is pertinent to this field as it assesses the medicinal value of a traditional herbal remedy, contributing to the body of knowledge around alternative treatments and their roles in modern therapeutic strategies.
9) Species:
'Species' refers to the specific types of organisms being studied—in this case, Aquilaria crassna. Understanding the characteristics and medicinal properties of particular species is vital for preserving biodiversity and harnessing the potential of specific plants for therapeutic use in medicine.
10) Edema (Oedema):
'Edema' describes the swelling caused by excess fluid trapped in the body’s tissues, which was induced in rats for anti-inflammatory studies. The evaluation of edema is critical for assessing the efficacy of medicinal compounds in reducing swelling and pain related to inflammatory responses in various conditions.
11) Pain (Paiṇ):
'Pain' is a key focus of the analgesic assessments in the study. It refers to the distressing sensation that results from tissue damage or inflammation. Investigating substances that alleviate pain is fundamental in pharmacology, as effective pain management is a significant aspect of patient care.
12) Northern India:
'Northern India' contextualizes the geographical distribution of Aquilaria species. The region's biodiversity informs the exploration of traditional herbal medicines utilized by local populations, enriching the scientific discourse surrounding the use of indigenous plants and their potential for broader medical applications.
13) Inflammation:
'Inflammation' is a biological response to harmful stimuli, and its modulation is assessed in the study. The investigation of anti-inflammatory effects is vital in developing treatments for various diseases where chronic inflammation plays a pivotal role, emphasizing the importance of identifying effective natural anti-inflammatory agents.
14) Substance:
'Substance' refers to the Aquilaria crassna leaves extract being studied. Understanding the chemical composition and biological effects of specific substances is fundamental in pharmacological research, as it relates to their potential therapeutic applications and the mechanisms that underlie their observed biological activities.
15) Container:
'Container' in this study signifies the apparatus used during experiments, such as the plexiglass on the hot plate. The design and conditions of a container can significantly influence the accuracy of measurements and the welfare of animal subjects, thereby impacting the validity of research findings.
16) Toxicity:
'Toxicity' refers to the degree to which a substance can cause harm to an organism. In this study, evaluating the toxicity of the Aquilaria crassna extract is essential to ensure safety and to assess the appropriate dosing for potential therapeutic uses, ensuring that it does not induce harmful effects.
17) Disease:
'Disease' represents the health conditions targeted by the therapeutic effects of Aquilaria crassna. By studying the extract’s properties, the research aims to provide alternative or adjunctive options to conventional treatments for various diseases, thereby enhancing patient health outcomes and contributing to holistic health approaches.
18) Forest:
'Forest' highlights the natural habitat of the Aquilaria crassna species, which contributes to its ecological significance and availability. Conservation of forests is crucial for sustaining biodiversity, which in turn supports the traditional and scientific exploration of medicinal plants and their applications in health care.
19) Cancer:
'Cancer' signifies one of the serious diseases that may benefit from treatments examined in pharmacological studies. The antioxidant and anti-inflammatory properties of herbal extracts, such as that from A. crassna, suggest potential therapeutic roles in cancer prevention and management within integrative medical frameworks.
20) India:
'India' alludes to the geographic and cultural context in which the Aquilaria species thrive and are traditionally utilized. Recognizing the heritage and regional applications of these plants informs the understanding of their relevance within both traditional and contemporary medicine, supporting further exploration.
21) House:
'House' refers to the institution or facility where the animals were housed for the study, indicating considerations for ethical standards and animal welfare. Proper housing is essential for maintaining the health of experimental subjects, thereby ensuring the validity and reliability of scientific research results.
22) Male (Mālē):
'Male' designates the sex of the experimental animals used in the study. Gender can significantly impact physiological responses, and thus the choice of male subjects may influence the interpretation of results and the overall understanding of the pharmacological effects being studied.
23) Genu (Geṇu):
'Genu' typically refers to a type of knee joint in anatomical terms, although this specific application may not be directly referenced in the study; it may represent the importance of anatomical terminology in understanding physical responses during experiments involving joint-related assessments of inflammation or pain.
24) Food:
'Food' emphasizes the context of Aquilaria crassna leaves as an edible entity, particularly in traditional diets. This highlights the dual role of plants as both nutritional and medicinal, encouraging investigations into their health benefits as dietary supplements and in food-related therapeutic applications.
25) Tree:
'Tree' categorizes Aquilaria crassna within the broader ecological context, reflecting its growth form, ecological role, and importance. Understanding the botanical characteristics of tree species like A. crassna enriches the study of their applications in medicine and conservation efforts related to natural resources.