Trial on Kusthadi Lepa and Jalaukavacharana for Yuvanpidaka.
Journal name: Ayushdhara
Original article title: A Randomized Comparative Clinical Trial to Evaluate the Effect of Kusthadi Lepa and Jalaukavacharana along with Manjishtha Churna in Yuvanpidaka
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
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Nilkanth Upadhyaya
PG Scholar, PG Dept. of Kriya Sharir, National Institute of Ayurveda, Deemed to be University, Jaipur, Rajasthan, India.
Sarika Yadav
Assistant Professor, PG Dept. of Kriya Sharir, National Institute of Ayurveda, Deemed to be University, Jaipur, Rajasthan, India.
Chhaju Ram Yadav
Professor, Dean (Research) & Head of Department, PG Dept. of Kriya Sharir, National Institute of Ayurveda, Deemed to be University, Jaipur, Rajasthan, India.
Ayushdhara:
(A peer-reviewed, bi-monthly open-access journal)
Full text available for: A Randomized Comparative Clinical Trial to Evaluate the Effect of Kusthadi Lepa and Jalaukavacharana along with Manjishtha Churna in Yuvanpidaka
Year: 2024 | Doi: 10.47070/ayushdhara.v11i2.1529
Copyright (license): CC BY-NC-SA 4.0
Download the PDF file of the original publication
Summary of article contents:
1) Introduction
Acne vulgaris, referred to as Yuvanpidaka in Ayurvedic medicine, is a common skin disorder that primarily affects adolescents aged 12 to 25 years. With around 85% of young adults experiencing acne, it poses significant psychological and physical challenges, potentially leading to scarring and associated mental health issues. In traditional Ayurvedic healthcare, the condition is attributed to an imbalance of Pitta dosha, leading to the development of pustules and papules on the skin. The present study aimed to evaluate the effectiveness of a combination of Ayurvedic treatments, namely Kusthadi Lepa and Jalaukavacharana, along with Manjishtha Churna, in managing symptoms of Yuvanpidaka over a specified treatment period.
2) Efficacy of Kusthadi Lepa
Kusthadi Lepa, an herbal paste made from ingredients like Dhanyaka, Vacha, Lodhra, and Kustha, was applied topically in conjunction with Manjishtha Churna, an oral supplement. The study sought to determine its efficacy against the classical symptoms of Yuvanpidaka, such as Kandu (itching), Daha (burning sensation), and various forms of skin eruptions (Pidaka). Results indicated that while both treatments yielded significant improvements, the presence of Kusthadi Lepa alongside internal therapies demonstrated enhanced relief from subjective symptoms, particularly when used in group B patients who also underwent Jalaukavacharana, or leech therapy.
3) Benefits of Jalaukavacharana
The application of Jalaukavacharana, which involves leech therapy, has shown notable effects on acne symptoms. This method, utilized in combination with Manjishtha Churna, produced highly significant results regarding both subjective patient-reported outcomes and objective clinical assessments. Group B, which received this combined treatment, showed a noticeable percentage of relief across multiple parameters compared to Group A, which only used Kusthadi Lepa. The mechanisms attributed to Jalaukavacharana include its anti-inflammatory properties derived from leech saliva, contributing to improved skin conditions and symptom alleviation.
4) Conclusion
The clinical trial reinforces the effectiveness of Ayurvedic treatments in managing Yuvanpidaka, with Kusthadi Lepa and Jalaukavacharana proving beneficial when combined with Manjishtha Churna. The results indicated a higher percentage of symptom relief for patients receiving the combined treatments, suggesting that integrating traditional Ayurvedic approaches can provide a holistic and effective strategy to tackle acne vulgaris. Thus, the study demonstrates the potential of these therapies in fostering improvements in skin health among young adults, emphasizing the need for further research in this domain.
FAQ section (important questions/answers):
What condition does the study focus on and why is it significant?
The study focuses on Yuvanpidaka, resembling acne vulgaris, which significantly impacts adolescents and young adults. This skin condition affects about 85% of individuals aged 12–25 years, making it one of the most common skin disorders globally.
What treatments were compared in the clinical trial?
The trial compared two treatment groups: Group A received Manjistha Churna and Kusthadi Lepa, while Group B received Manjistha Churna and Jalaukavacharana, both administered for a duration of 30 days to assess their effectiveness in managing Yuvanpidaka.
What were the results of the treatment for Yuvanpidaka?
The results showed significant improvement in symptoms for both groups, but Group B demonstrated more substantial results with a relief percentage of 61.25%, compared to 39.82% in Group A, indicating Jalaukavacharana's higher effectiveness.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Trial on Kusthadi Lepa and Jalaukavacharana for Yuvanpidaka.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Lepa:
Lepa refers to a form of local application used in Ayurvedic treatments. In the discussed study, *Kusthadi Lepa* was applied to the skin to treat *Yuvanpidaka*, demonstrating its therapeutic effects through active principles that absorb and act on the skin's surface symptoms.
2) Manjishtha (Manjistha, Mamjishtha):
Manjishtha, also spelled as Manjista, was used internally in the form of *Manjishtha Churna* and externally in various lepas. Its anti-inflammatory and skin-purifying properties were significant in managing *Yuvanpidaka*.
3) Drug:
Various Ayurvedic drugs, including herbal formulations like *Kusthadi Lepa* and *Manjistha Churna*, were evaluated in the study for their efficacy in treating *Yuvanpidaka* (acne). These drugs included ingredients known for their anti-inflammatory and antioxidative properties.
4) Kushthadi (Kusthadi):
Kusthadi refers to a compound formulation used in *Kusthadi Lepa* consisting of herbs like *Dhanyaka*, *Vacha*, *Lodhra*, and *Kustha*. It was used in one of the treatment groups in the study to manage *Yuvanpidaka*.
5) Kushtha (Kustha):
Kustha is one of the ingredients in *Kusthadi Lepa* known for its antimicrobial and anti-inflammatory properties, contributing to its effectiveness in treating *Yuvanpidaka*.
6) Rasa (Rasha):
Rasa, in Ayurveda, refers to the taste or essence of a substance, influencing its therapeutic effects. Ingredients in the study had varying *Rasa* such as *Madhura* (sweet), *Tikta* (bitter), and *Kashaya* (astringent) that act synergistically to treat *Yuvanpidaka*.
7) Dhanyaka:
Dhanyaka, also known as coriander, is included in the *Kusthadi Lepa* for its *Madhura* Rasa and *Snigdha* Guna, which help reduce inflammation and soothe the skin in *Yuvanpidaka*.
8) Pidaka:
Pidaka refers to the eruptions or lesions associated with acne. The study evaluated changes in the number of *Pidaka* to assess the effectiveness of treatments like *Kusthadi Lepa* and *Jalaukavacharana*.
9) Vaca:
Vacha is an ingredient in *Kusthadi Lepa* known for its medicinal properties, including anti-inflammatory and skin healing effects, making it useful in the treatment of *Yuvanpidaka*.
10) Daha:
Daha pertains to the burning sensation experienced with acne. The study measured improvements in *Daha* as a symptom of *Yuvanpidaka* following treatments with *Kusthadi Lepa* and *Manjistha Churna*.
11) Snigdhata:
Snigdhata refers to the unctuous or oily nature of the skin, contributing to the severity of acne. The study evaluated reductions in *Snigdhata* as one of the symptomatic improvements in *Yuvanpidaka*.
12) Pain:
Pain, also referred to as *Ruja* in the study, is one of the symptoms of acne evaluated for improvement following treatments. Reductions in pain were considered a significant indicator of treatment efficacy.
13) Disease:
The primary disease under study was *Yuvanpidaka* (acne vulgaris), a common adolescent skin condition characterized by eruptions, inflammation, and other symptoms treated using Ayurvedic methods.
14) Kandu (Kamdu):
Kandu refers to itching, a common symptom of *Yuvanpidaka* (acne). The study measured changes in itching intensity as one of the parameters for evaluating treatment efficacy.
15) Virya:
Virya in Ayurveda denotes the potency or energy of a substance. Ingredients used in *Kusthadi Lepa* and *Manjistha Churna* were chosen for their particular *Virya* to effectively manage *Yuvanpidaka*.
16) Burning sensation:
Burning sensation, or *Daha*, is a symptom of acne evaluated in the study. Improvements in *Daha* were significant for assessing the treatment effects of the applied and ingested Ayurvedic formulations.
17) Vaivarṇya (Vaivarnya, Vaivanrya):
Vaivarnya refers to discoloration or black scars associated with acne. The study measured improvements in *Vaivarnya* to evaluate the efficacy of *Kusthadi Lepa*, *Jalaukavacharana*, and *Manjistha Churna*.
18) Madhura:
Madhura refers to the sweet taste or essence in Ayurvedic treatments. *Dhanyaka* with *Madhura Rasa* played a role in reducing acne symptoms by normalizing vitiated doshas.
19) Kapha:
Kapha is one of the three doshas in Ayurveda, associated with qualities like oiliness and structure. The study treatments aimed to balance *Kapha* to manage *Yuvanpidaka* effectively.
20) Lodhra:
Lodhra is an ingredient in *Kusthadi Lepa* known for its anti-inflammatory and antimicrobial properties, aiding in the treatment of *Yuvanpidaka*.
21) Ruja:
Ruja in Ayurveda denotes pain, one of the primary symptoms assessed in the treatment of *Yuvanpidaka* using Ayurvedic formulations.
22) Madhurarasa (Madhura-rasa):
Madhura-rasa refers to the sweet taste, often seen in Ayurvedic herbs like *Dhanyaka*. Its presence was crucial in the treatments for balancing doshas and alleviating symptoms of *Yuvanpidaka*.
23) Shrava (Srava):
Srava, equivalent to *Shrava*, denotes discharge observed in acne conditions. Reductions in *Srava* were evaluated to determine the effectiveness of Ayurveda-based treatments for *Yuvanpidaka*.
24) Vipaka:
Vipaka refers to the post-digestive effect of a substance in Ayurveda. Herbs in the study had specific *Vipaka* properties contributing to their effectiveness in managing *Yuvanpidaka*.
25) Tikta:
Tikta, or bitter taste, is a quality in several Ayurvedic ingredients like *Manjistha* and *Kustha* used for their anti-inflammatory and antimicrobial properties in treating *Yuvanpidaka*.
26) Ushna (Usna):
Ushna denotes the hot potency of Ayurvedic medicines. Herbs with *Ushna Virya* like *Kustha* and *Manjistha* were used to balance Kapha and Vata doshas in treating *Yuvanpidaka*.
27) Katu:
Katu, or pungent taste, is present in herbs used in the treatments for *Yuvanpidaka*. *Katu Vipaka* aids in digestion and metabolism, helping reduce symptoms like inflammation and discharge.
28) Guna:
Guna refers to the qualities or properties of a substance. In the study, ingredients with *Tikta*, *Katu*, and *Madhura rasa* were selected for their specific *Guna* to treat *Yuvanpidaka*.
29) Upadhyaya:
Nilkanth Upadhyaya is one of the authors of the study, who contributed to the research on the effectiveness of Ayurvedic treatments on *Yuvanpidaka*.
30) Sharika (Sarika):
Sarika Yadav is one of the authors involved in the study, analyzing the efficacy of *Kusthadi Lepa*, *Jalaukavacharana*, and *Manjistha Churna* in treating *Yuvanpidaka*.
31) Dosha (Dosa):
Doshas are the three functional energies in Ayurveda—*Vata*, *Pitta*, and *Kapha*. The imbalance of doshas was addressed in the study using specific Ayurvedic treatments to manage *Yuvanpidaka*.
32) Rakta:
Rakta, meaning blood, plays a crucial role in Ayurvedic diagnosis and treatment. The study involved procedures like *Jalaukavacharana* (leech therapy) which directly acts on *Rakta* to treat *Yuvanpidaka* symptoms.
33) Medicine:
Medicines in the context of the study refer to Ayurvedic formulations like *Kusthadi Lepa*, *Manjistha Churna*, and *Jalaukavacharana* used to treat *Yuvanpidaka*.
34) Pitta:
Pitta, one of the three doshas in Ayurveda, is associated with heat and metabolism. The treatments aimed to balance *Pitta* to prevent and manage *Yuvanpidaka* symptoms.
35) Blood:
Blood, or *Rakta*, was involved in treatments like *Jalaukavacharana* (leech therapy), which helped in managing symptoms of *Yuvanpidaka* by affecting the blood properties and circulation.
36) Vata:
Vata is another primary dosha in Ayurveda involved in movement and function. Balancing *Vata* through treatments like *Manjistha Churna* was crucial in addressing *Yuvanpidaka*.
37) Kshudraroga (Kshudra-roga, Ksudraroga):
Kshudra-roga refers to minor diseases in Ayurvedic classification. *Yuvanpidaka* falls under this category, and its management was discussed using Ayurvedic treatments in the study.
38) Vatadosha (Vatadosa, Vata-dosha):
*Vata-dosha* governs movement and communication in Ayurveda. Treatments aimed to balance *Vata-dosha* were crucial in managing acne symptoms in the study.
39) Madhyama:
Madhyama refers to the middle age stage in Ayurveda. In the study, *Yuvanpidaka* was prevalent in the *Madhyama Vaya* stage, affecting adolescents and young adults.
40) Shodhana (Sodhana):
Sodhana refers to purification therapies in Ayurveda, including procedures like *Vamana*, *Virechana*, and *Rakta Mokshana* for treating diseases like *Yuvanpidaka*.
41) Kshudra (Ksudra):
Kshudra is a term in Ayurveda referring to minor ailments. *Yuvanpidaka* is listed under *Kshudra Roga* and was the focus of the study's treatment strategies.
42) Kashaya (Kasaya):
Kashaya is an astringent taste in Ayurveda. Herbs with *Kashaya Rasa* like *Lodhra* were used in the study for their therapeutic effects on *Yuvanpidaka*.
43) Samana (Shamana):
Shamana treatments in Ayurveda involve pacifying therapies. The study used *Shamana Chikitsa* (like *Kusthadi Lepa*) alongside *Sodhana Chikitsa* to manage *Yuvanpidaka*.
44) Kshata (Ksata):
Kshata refers to tissue injury or damage. The study's treatments included ingredients that promote healing of *Kshata*, thereby managing symptoms like *Vaivarnya* in *Yuvanpidaka*.
45) Kshina (Ksina):
Kshina denotes reduced or decreased condition. Ayurvedic formulations aimed to alleviate *Kshina* conditions of tissues affected in *Yuvanpidaka*.
46) Karma (Karman):
Karma in Ayurveda refers to the action or therapeutic effect of a treatment. Procedures like *Jalaukavacharana* and applications like *Kusthadi Lepa* exhibit specific *Karma* in treating *Yuvanpidaka*.
47) Laghu:
Laghu means light or easily digestible properties. Herbs with *Laghu Guna* reduced the unctuousness and heaviness associated with *Kapha* in treating *Yuvanpidaka*.
48) India:
India is the country where the study was conducted, specifically at the National Institute of Ayurveda in Jaipur, Rajasthan, focusing on Ayurvedic treatments for *Yuvanpidaka*.
49) Roga:
*Roga* is the term for disease in Ayurveda. *Yuvanpidaka* is considered a *Kshudra Roga* affecting the young population, focused on acne treatment in the study.
50) Raktamokshana (Raktamoksana, Rakta-mokshana):
Rakta-mokshana refers to blood-letting therapy in Ayurveda. *Jalaukavacharana*, a form of *Rakta-mokshana*, was used in the study to manage *Yuvanpidaka*.
51) Sadharanadesha (Sadharanadesa, Sadharana-desha):
Sadharanadesha is the term for a common area. The study mentions this demographic detail about the patients but does not explore it deeply.
52) Madhyamasatva (Madhyama-satva):
*Madhyama-satva* refers to moderate mental strength. The study classified patients using this criterion but did not focus on it for therapeutic implications.
53) Transformation (Transform, Transforming):
Transformation implies change, seen in the therapeutic context where Ayurvedic treatments lead to symptom improvement. The procedures aimed for such transformations in managing *Yuvanpidaka*.
54) Antibiotic (Antibacterial):
Anti-bacterial properties of herbs like *Kustha* and *Manjistha* were significant in managing *Yuvanpidaka*. The study highlights their role in reducing bacterial infections associated with acne.
55) Ranjakapitta (Ranjaka-pitta):
Ranjaka-pitta denotes a subtype of *Pitta* responsible for digestion. Treatments aimed to balance *Ranjaka-pitta* were useful in managing internal aspects of *Yuvanpidaka*.
56) Krurakoshtha (Krurakostha, Krura-koshtha):
Krura-kostha means a type of intestinal peristalsis or bowel habit. The study mentions this detail about patients but does not focus on it therapeutically.
57) Aharashakti (Aharasakti, Ahara-shakti):
Ahara-shakti refers to digestive power or the capacity to digest food. Patients in the study were assessed for *Ahara-shakti* to correlate dietary impact on *Yuvanpidaka*.
58) Inflammation:
Inflammation is a key symptom in *Yuvanpidaka* (acne), where Ayurvedic herbs with anti-inflammatory properties like *Manjistha* were used in the study for treatment.
59) Mahakashaya (Mahakasaya, Maha-kashaya):
Mahakashaya refers to categories of herbs in Ayurveda. *Manjistha* is listed under *Varnya Mahakashaya*, used in the study for its skin-purifying effects on *Yuvanpidaka*.
60) Prakshalana (Praksalana):
Prakshalana involves washing or cleansing procedures in Ayurveda. The study refers to its role in *Shamana Chikitsa* for handling *Yuvanpidaka*.
61) Mukhadushika (Mukhadusika, Mukha-dushika):
Mukhadusika is another term for facial acne in Ayurveda, synonymous with *Yuvanpidaka*. The study assessed treatments targeting *Mukhadusika* symptoms.
62) Upashoshana (Upasosana):
Upashoshana refers to the drying up or desiccating effect. Ayurvedic treatments aimed to achieve *Upashoshana* of excess *Kapha* to manage symptoms like unctuousness in *Yuvanpidaka*.
63) Pittadosha (Pittadosa, Pitta-dosha):
*Pitta-dosha* is one of the three doshas in Ayurveda, responsible for metabolism and heat. The study's treatments aimed to balance *Pitta-dosha* to manage acne symptoms.
64) Kaphadosha (Kaphadosa, Kapha-dosha):
*Kapha-dosha* represents the structural and fluid principle in Ayurveda. Imbalance in *Kapha-dosha* was treated using Ayurvedic herbs to manage *Yuvanpidaka*.
[Note: The above list is limited to 75. Total glossary definitions available: 120]