Evaluation of ekangaveeraras, ksheerabalataila, balamulakwatha, panasapatra.
Journal name: Ayushdhara
Original article title: Physicochemical, phytochemical and hptlc evaluation of ekangaveeraras, ksheerabalataila, balamulakwatha and panasapatra
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
This page presents a generated summary with additional references; See source (below) for actual content.
Summary of article contents:
Introduction
The article presents a comprehensive analysis of several Ayurvedic formulations—Ekangaveeraras, Ksheerabalataila, Balamulakwatha, and Panasapatra—through physicochemical, phytochemical, and HPTLC evaluations. These formulations are associated with the treatment of Arditavata, a condition characterized by facial paralysis with symptoms akin to Bell's palsy, such as mouth deviation and deafness. The pharmacological actions of these herbal products can be elucidated through the analysis of their active principles and constituents, which informs their therapeutic applications in traditional medicine.
Pharmacological Analysis of Active Ingredients
One crucial aspect examined is the presence of various phytochemicals in the formulations. The analysis revealed a plethora of constituents, including carbohydrates, steroids, alkaloids, flavonoids, and glycosides. These compounds exhibit both water and alcohol solubility, indicating their potential bioavailability and efficacy. For example, while carbohydrates, alkaloids, and flavonoids are soluble in both water and alcohol, steroids and glycosides are primarily alcohol-soluble. The study emphasizes that the diversity of these active ingredients directly correlates with the biological activity of each formulation, thereby enhancing the understanding of their therapeutic effects.
HPTLC Evaluation Results
The article also details the use of HPTLC (High-Performance Thin Layer Chromatography) to establish the fingerprint profiles of the formulations. By applying different concentrations of samples to chromatographic plates and developing them in varying solvents, distinct Rf values and visual characteristics of the compounds were recorded. For instance, Ksheerabalataila exhibited multiple distinct spots under UV light and post-derivatization, indicating a complex composition rich in therapeutic constituents. This methodological approach not only helps in the characterization of the formulations but also reinforces the importance of HPTLC as a tool in quality control and standardization in herbal medicine.
Conclusion
The findings underscore the significance of both qualitative and quantitative analyses of Ayurvedic formulations in understanding their therapeutic potential. The presence of diverse phytoconstituents suggests a multifaceted approach to treatment, aligning with holistic principles fundamental to Ayurveda. By elucidating the complexities of these formulations through rigorous scientific methodologies, the research enhances both the credibility and applicability of traditional herbal medicine, paving the way for further investigation into their mechanisms of action and therapeutic efficacy.
Original source:
This page is merely a summary which is automatically generated hence you should visit the source to read the original article which includes the author, publication date, notes and references.
*Santosh N. Belavadi
Final PhD Scholar, Department of P.G studies in Kayachikitsa, D.G.M Ayurveda Medical College, Gadag, Karnataka
Prashanth A.S
Professor and Head, Department of P.G studies in Kayachikitsa, D.G.M Ayurveda Medical College, Gadag, Karnataka
Ayushdhara:
(A peer-reviewed, bi-monthly open-access journal)
Full text available for: Physicochemical, phytochemical and hptlc evaluation of ekangaveeraras, ksheerabalataila, balamulakwatha and panasapatra
Year: 2017
Copyright (license): CC BY-NC-SA 4.0
Download the PDF file of the original publication
FAQ section (important questions/answers):
What are the main components evaluated in the study?
The study evaluates physicochemical properties, phytochemical constituents, and HPTLC profiles of Ayurvedic formulations including Ekangaveeraras, Ksheerabalataila, Balamulakwatha, and Panasapatra.
What significance do the findings of phytochemical analysis hold?
The findings indicate the presence of therapeutically active components, such as carbohydrates, alkaloids, and flavonoids. These are essential for understanding the biological activity and therapeutic potential of the formulations in treating diseases like Arditavata.
What methods were used for HPTLC analysis in the study?
HPTLC analysis involved partitioning samples with methanol, applying them to silica gel plates, developing in specific solvent systems, and visualizing under UV light. The Rf values of the constituents were then recorded post-derivation.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Evaluation of ekangaveeraras, ksheerabalataila, balamulakwatha, panasapatra.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Drug:
A drug is any substance used to diagnose, cure, mitigate, treat, or prevent disease. In the provided text, various Ayurvedic drugs like Ekangaveeraras, Ksheerabalataila, and Balamulakwatha have been evaluated for their physicochemical and phytochemical properties.
2) Phytochemical:
Phytochemicals are chemical compounds produced by plants. They are significant because their presence impacts the biological activity of plant-based drugs. The text discusses the phytochemical analysis of various formulations, confirming elements like alkaloids and flavonoids.
3) Belavadi:
Santosh N. Belavadi is identified as the final PhD scholar who conducted the research on the physicochemical, phytochemical, and HPTLC evaluation of certain Ayurvedic formulations.
4) Samtosha (Samtosa, Santosa, Santosha, Santosh):
Santosh N. Belavadi is the main researcher mentioned in the document who conducted the studies on Ayurvedic medicines. He is affiliated with the Department of P.G studies in Kayachikitsa, D.G.M Ayurveda Medical College, Gadag, Karnataka, India.
5) Powder:
In the context of the document, powder refers to the form of substances or drugs like Balamulakwathachurna and Panasapatra, which are evaluated for their physicochemical and phytochemical properties.
6) Pharmacological:
Pharmacological analysis focuses on the study of drug action. The document discusses the pharmacological analysis of Ayurvedic formulations such as Ekangaveeraras and Ksheerabalataila to better understand their mode of action.
7) Ayurveda (Ayus-veda):
Ayurveda is a traditional system of medicine deeply rooted in India, aiming at the holistic wellness of an individual. The document evaluates various Ayurvedic formulations to understand their effectiveness in treating Ardita, equated with Bell's palsy.
8) Karnataka:
Karnataka is a state in India where D.G.M Ayurveda Medical College is located. This institution is part of the research study headed by Santosh N. Belavadi and Prashanth A.S., mentioned in the document.
9) Flavonoid:
Flavonoids are a type of phytochemical known for their antioxidant properties. The presence of flavonoids in the evaluated formulations, such as in Balamulakwathachurna, indicates their potential therapeutic benefits.
10) Ardita (Arddita):
Ardita is an Ayurvedic term for a condition characterized by symptoms similar to Bell's palsy, including facial paralysis. The document examines treatments for Ardita using Ayurvedic formulations.
11) Jack fruit (Jack fruit tree):
Jack fruit is referred to in the document as Panasapatra, which is the leaf powder of the jackfruit tree. It is one of the evaluated substances for its physicochemical and phytochemical properties.
12) Deafness:
Deafness is one of the symptoms associated with Bell's palsy, which in Ayurvedic terms is called Ardita. The document discusses treatments for Ardita, potentially improving symptoms like deafness.
13) Disease:
The document focuses on Ardita, a disease in Ayurveda that corresponds to Bell's palsy. It involves symptoms like facial paralysis and deviation of the mouth, and treatments using various Ayurvedic drugs are evaluated.
14) Gelatin:
Gelatin is used in the document to test for the presence of tannins as part of the preliminary phytochemical investigations. For example, the gelatin test is used to identify the presence of tannins in plant extracts.
15) Lalata:
Lalata is a Sanskrit term mentioned in the document meaning forehead. In Ardita (facial paralysis), the region of the Lalata (forehead) is affected.
16) Soniya:
Soniya Education Trust, specifically its Soniya College of Pharmacy in Dharwad, is acknowledged for its role in supporting the research presented in the document.
17) Akshi (Aksi):
Akshi refers to the eyes in Sanskrit. In the context of Ardita, the deviation or paralysis affects the region of the eyes, among other facial parts.
18) India:
India is the country where the research on Ayurvedic formulations, evaluating their efficacy in treating Ardita, was conducted. Institutions from Karnataka, India, were involved in this research.
19) Ayus (Ayush):
AYUSH stands for Ayurveda, Yoga & Naturopathy, Unani, Siddha, and Homoeopathy. The journal, AYUSHDHARA, which published the research, is dedicated to studies in AYUSH and allied systems.
20) Blood:
Blood is involved in the haemolysis test mentioned in the phytochemical analysis. The test determines the presence of saponin glycosides.
21) Hanu:
Hanu is a Sanskrit term meaning jaw. It is one of the facial areas affected by Ardita, causing symptoms like mouth deviation.
22) Nasa (Nasha):
Nasa is the Sanskrit word for nose. In Ardita, symptoms may include the distortion of the nasal area.
23) Bhru:
Bhru means eyebrows in Sanskrit. In the context of Ardita described in the document, the condition affects the region around the Bhru (eyebrows).
24) Dravyaguna (Dravya-guna):
Dravyaguna is a branch of Ayurveda focusing on the properties of medicinal substances. Dr. Manjunath Ajanal, thanked in the document, is an Assistant Professor in this field.
25) Vatavyadhi (Vata-vyadhi):
Vatavyadhi are a group of diseases in Ayurveda caused by the imbalance of Vata dosha. Ardita, or facial paralysis, is classified under Vatavyadhi.
26) Substance:
In the context of the document, the substances analyzed include Ekangaveeraras, Balamulakwatha, Ksheerabalataila, and Panasapatra. They are studied for their chemical constituents and therapeutic effects.
27) Education:
The document acknowledges educational institutions like D.G.M Ayurveda Medical College and Soniya College of Pharmacy for supporting the research activities.
28) Prasanna:
Dr. Prasanna is acknowledged in the document for his contributing role in the research. He is affiliated with Soniya Education Trust’s Soniya College of Pharmacy.
29) Mineral:
Minerals are mentioned as part of the bioactive compounds in plant substances. They play a role in the overall therapeutic efficacy of Ayurvedic formulations evaluated in the document.
30) Prabhu:
Suchitra N. Prabhu, M.Pharm, is mentioned in the acknowledgements for her role as a Trainee Research Officer contributing to the study.
31) Vataja (Vata-ja):
Vataja refers to conditions caused by an imbalance in Vata dosha. Ardita, the primary focus of the document, is classified as a Vataja disorder.
32) Vyadhin (Vyadhi):
In Ayurveda, Vyadhi means disease. Ardita, analyzed in the document, is a Vataja Vyadhi, reflecting symptoms like facial paralysis.
33) Kumar:
Dr. KN Sunil Kumar, who holds both M.Sc. and Ph.D. qualifications, is acknowledged for his role as a Senior Research Officer in the study.
34) Glass:
Glass is mentioned in the context of the laboratory equipment used for drying and measuring moisture content in the plant substances like Panasapatra choorna.
35) Rasa (Rasha):
Rasa is the taste or essence in Ayurveda. Ekangaveerarasa, one of the evaluated formulations, literally means ‘Ekanga (limb) Veera (strength) Rasa (essence)’. Its composition and efficacy are analyzed.
36) Shiras (Siras, Siro, Shirash):
SIRO stands for Scientific and Industrial Research Organization. The SDM Center for Research in Ayurveda and Allied Sciences, a recognized SIRO, contributed to the research.
37) Viru:
[see source text or glossary: Viru]