A novel ayurvedic anti diabetic medicine
Journal name: Ancient Science of Life
Original article title: A novel ayurvedic anti diabetic medicine
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
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Summary of article contents:
Introduction
The study presented in the article focuses on the anti-diabetic properties of Nagabhasma, a preparation derived from lead (Naga) according to ancient Ayurvedic texts, specifically the Rasaratnasamuccaya. While lead is generally considered toxic in modern medicine, ancient Ayurvedic practices involve a meticulous purification process that transforms it into a non-toxic, therapeutic agent. The preparation involves repeated purification and processing, which is believed to endow the substance with beneficial properties, particularly in treating diabetes mellitus (madhumeha).
Rasayana Effect of Nagabhasma
An essential concept highlighted in the study is the rasayana effect of Sastiputa Nagabhasma, which emphasizes the enhancement of overall well-being and immunity in patients. Clinical trials involving 30 diabetic patients demonstrated significant results; 90% reported a sense of well-being, and 65% exhibited reduced blood sugar levels. Notably, patients taking Sastiputa Nagabhasma alone showed no hypoglycemic effects, while others taking it alongside synthetic hypoglycemics benefited from improved management of blood sugar levels. This suggests that Nagabhasma functions not only as a therapeutic agent but also as a supportive treatment for enhancing the efficacy of conventional medications.
Conclusion
The findings of the clinical study support the potential of Sastiputa Nagabhasma as a viable alternative or adjunctive treatment for managing diabetes mellitus. The lack of adverse effects alongside the reported improvements in symptoms and blood glucose levels underscores its promise in Ayurvedic medicine. Given that it may provide essential benefits without the toxic repercussions typically associated with lead, Sastiputa Nagabhasma emerges as a noteworthy candidate for further research and consideration in the holistic approach to diabetes management.
Original source:
This page is merely a summary which is automatically generated hence you should visit the source to read the original article which includes the author, publication date, notes and references.
Anjana Chaube, T.N Nagraja, S.K Dixit, J.K Agrawal, Mohan Kumar, Bhanu Prakash
Ancient Science of Life:
(A quarterly multi-disciplinary scientific research journal in Ayurveda)
Full text available for: A novel ayurvedic anti diabetic medicine
Year: 1995
Copyright (license): CC BY-NC-SA
Download the PDF file of the original publication
FAQ section (important questions/answers):
What is Nagabhasma and how is it prepared?
Nagabhasma is a processed form of lead described in Ayurveda. It is purified through multiple methods involving heating and treating with herbal decoctions, then calcined repeatedly to eliminate toxicity and enhance therapeutic properties.
How does Nagabhasma act as an anti-diabetic medicine?
Nagabhasma is believed to enhance immunity and general well-being, thus potentially alleviating symptoms of diabetes. Clinical studies indicated its effectiveness in reducing blood sugar levels, accompanied by a sense of well-being among patients.
What were the results of the clinical study on Nagabhasma?
In a study of 30 diabetic patients, 70% showed symptom improvement. Additionally, 65% experienced reduced blood sugar levels, particularly those using Nagabhasma alone, while no significant side effects were reported.
Can Nagabhasma be used with synthetic diabetes medications?
Yes, Sastiputa Nagabhasma can be recommended alongside synthetic medications. Patients were advised to reduce or discontinue synthetic drugs due to the hypoglycemic effects observed when combined with Nagabhasma.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “A novel ayurvedic anti diabetic medicine”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Naga (Nāga, Nag, Nāgā):
Naga refers to lead, a metal utilized in Ayurvedic practices. Despite being toxic in Western medicine, it's processed through ancient techniques such as Rasaratnasamuccaya to detoxify and pharmacologically transform it into therapeutic forms. This toxic metal, when processed appropriately, can be used for various treatments, including diabetes management.
2) Drug:
In the context of Ayurveda, a drug is any medicinal substance or preparation aimed at curing, alleviating, or preventing diseases. Sastiputa Nagabhasma is a drug specifically formulated to manage diabetes mellitus. This term encompasses both natural extracts and processed substances like Nagabhasma, which collectively contribute to healthy outcomes.
3) Medicine:
Medicine encompasses the science and practice of diagnosing, treating, and preventing diseases. Ayurvedic medicine, including the use of Sastiputa Nagabhasma, emphasizes holistic approaches that encompass body, mind, and spirit. The term signifies not only pharmacological substances but also herbal formulations, lifestyle practices, and preventive measures to maintain health.
4) Nagabhasma (Nāgabhasma, Naga-bhasma):
Nagabhasma is a specific Ayurvedic preparation made from lead that has been processed to eliminate toxic properties. Its qualities are harnessed for treating various conditions, particularly diabetes mellitus. The term underscores the importance of traditional preparation methods in Ayurveda, combining science and holistic health principles for therapeutic benefits.
5) Bhasma (Bhasman):
Bhasma refers to an ash-like substance derived from the incineration of metals and minerals in Ayurvedic medicine. This process enhances the bioavailability of the materials, allowing them to safely interact with the body. Bhasma formulations are fundamental in Ayurveda for treating chronic diseases while minimizing toxicity.
6) Shodhana (Śodhana, Sodhana):
Sodhana is the purification process in Ayurveda that aims to eliminate impurities and toxins from medicinal substances. This technique is foundational for preparing metals like Naga for therapeutic use. The effectiveness and safety of the end products, like Nagabhasma, largely depend on thorough sodhana processes undertaken before further treatments.
7) Blood:
Blood is a crucial bodily fluid that carries oxygen, nutrients, hormones, and waste products throughout the body. In the context of diabetes, blood glucose levels are a primary focus for diagnosis and treatment. Ayurvedic remedies, including Nagabhasma, are formulated to help balance these levels and improve overall health.
8) Sugar:
Sugar, primarily glucose, is vital for energy but can pose health risks when levels remain elevated, as seen in diabetes. The management of blood sugar levels is central to diabetes treatment. In Ayurveda, formulations like Sastiputa Nagabhasma aim to reduce excessive sugar and promote metabolic balance.
9) Ayurveda (Āyurveda, Ayus-veda):
Ayurveda is an ancient Indian system of medicine that emphasizes balance and wellness through natural remedies, diet, and lifestyle practices. It employs holistic approaches to health, utilizing herbs, minerals, and therapeutic techniques like those described in Rasaratnasamuccaya to treat diseases such as diabetes mellitus effectively.
10) Rasayana (Rasa-ayana, Rasāyana, Rāsāyana):
Rasayana refers to rejuvenating therapies in Ayurveda that aim to improve health, longevity, and vitality. These therapies enhance 'ojas'—a concept synonymous with immunity and well-being. The use of Nagabhasma showcases Rasayana principles, as its preparations are intended to boost overall health while minimizing disease progression.
11) Quality:
Quality in relation to Ayurvedic preparations refers to the therapeutic efficacy and safety of the substances used. The meticulous preparation processes of drugs like Sastiputa Nagabhasma enhance their quality, ensuring they are non-toxic and effective. Quality assurance in Ayurveda is crucial for the trust and effectiveness of treatments.
12) Kapota (Kāpota):
Kapota, meaning dove, describes the color of certain Ayurvedic preparations that may appear as a blend of black and white. In the context of Sastiputa Nagabhasma, this term may refer to the visual characteristics of the final product, which signifies the completion of a thorough and successful processing cycle.
13) Varna (Varṇā, Varṇa):
Varna translates to color, an essential attribute in identifying and categorizing Ayurvedic preparations. The specific coloration of medicines like Nagabhasma often reflects their stage of processing and quality. Color can also indicate the purity and effectiveness of a formulation, thus playing a critical role in Ayurveda.
14) Rasaratnasamuccaya (Rasaratna-samuccaya):
Rasaratnasamuccaya is a core Ayurvedic text focused on the alchemical processing of metals and minerals into therapeutic forms. This foundational text outlines various methods, including those for preparing Nagabhasma, and serves as a guide for practitioners in the safe and effective use of these preparations.
15) Samanya (Sāmānya, Sāmanya):
Samanya refers to the general or common processes in Ayurvedic medicine related to the purification and preparation of substances. In the context of Naga, samanya sodhana involves standard methods that ensure the removal of impurities, establishing the foundation for subsequent therapeutic applications like Nagabhasma.
16) Science (Scientific):
Science, in a broader context, refers to the systematic study of the natural world through observation and experimentation. In Ayurveda, the integration of traditional knowledge with scientific principles enables a better understanding of herbal and mineral medicines, affirming the relevance and potential of products like Sastiputa Nagabhasma.
17) Kvatha (Kvātha):
Kvatha is an Ayurvedic term for a decoction made by boiling herbal material in water to extract the active principles. This process enhances the bioavailability and efficacy of the constituents. In the preparation of Nagabhasma, kvathas from plants like Nirgundi and Vasa are integral to the purification process.
18) Marana (Maraṇa, Māraṇa):
Marana is the Ayurvedic process of incinerating and transforming herbal and mineral substances into bhasmas. This pivotal step renders the materials more bioavailable while minimizing their toxicity. In the context of Nagabhasma, marana enhances the therapeutic potential of lead while ensuring it becomes safe for consumption.
19) Adhatoda vasica:
Adhatoda vasica, commonly known as Vasaka, is a medicinal herb used in Ayurveda for various treatments, including respiratory and diabetic conditions. The kvatha made from this plant is utilized in the processing of Naga to enhance its therapeutic qualities, showcasing the importance of herb-metal combinations in Ayurvedic medicine.
20) Curcuma longa:
Curcuma longa, known as turmeric, is a widely used herb in Ayurveda for its anti-inflammatory, antioxidant, and medicinal properties. In the preparation of Nagabhasma, Turmeric powder (Haridra churna) plays a role in the purification process, not only enhancing the preparation's therapeutic effectiveness but also supporting overall health.
21) Sharavasamputa (Śarāvasaṃpuṭa, Sharava-samputa):
Sarava-samputa refers to the container or process used to encase and protect Ayurvedic formulations during their preparation. This step is crucial for maintaining the integrity and efficacy of the substances like Nagabhasma during the various heating and cooling cycles required for achieving therapeutic transformation.
22) Rasashastra (Rasa-shastra, Rasaśāstra):
Rasashastra is a branch of Ayurveda focusing on the science of alchemy and the processing of metals and minerals for medical use. It encompasses knowledge about purification, transformation, and the therapeutic application of substances like Naga, forming a critical foundation for developing Ayurvedic medicines such as Nagabhasma.
23) Madhurarasa (Madhura-rasa):
Madhurarasa refers to the sweet taste, which is considered beneficial in Ayurveda. This concept relates to the balancing of doshas and providing nourishment. In terms of diabetes, controlling the taste profile in dietary choices and medicinal formulations is essential for managing blood sugar and maintaining overall health effectively.
24) Metallurgy:
Metallurgy is the science and technology involved in the extraction and processing of metals. In the context of Ayurvedic practices, metallurgy plays a role in understanding how metals like Naga can be purified and transformed into safe, effective medicines, broadly influencing the field of Rasashastra.
25) Discussion:
Discussion in scientific literature reflects critical analysis and synthesis of research findings. In the context of this study, it covers the observed effects of Sastiputa Nagabhasma on diabetic patients, examining how traditional Ayurvedic principles align with modern clinical practices to achieve desired health outcomes while ensuring patient safety.
26) Manahshila (Manaḥśilā, Manah-shila, Manas-shila, Mānaḥśila, Manaḥśila):
Manahsila, or orpiment, is a toxic mineral traditionally used in Ayurvedic medicine after thorough processing to eliminate its harmful components. In formulations like Nagabhasma, its use symbolizes the historical understanding of mineral manipulations to harness therapeutic benefits while ensuring safety through extensive purification and preparation practices.
27) Apamarga (Apāmārga, Apamārga):
Apamarga, or Achyranthes aspera, is valued in Ayurveda for its medicinal properties, including its ability to help control blood sugar levels. The powder of Apamarga is employed during the preparation of Nagabhasma, showcasing the combination of herbal and mineral elements to enhance the efficacy of Ayurvedic treatments for diabetes.
28) Gajaputa (Gajapuṭa, Gaja-puta):
Gajaputa is a traditional Ayurvedic method involving packing substances in a mixture of clay, followed by the application of intense heat, often likened to cooking within an oven. This technique is crucial in the marana process for metals like Naga, ensuring complete transformation into safe and effective medicinal bhasma.
29) Putapaka (Puṭapāka, Puta-paka):
Putapaka signifies the heating and processing technique used to convert raw materials into medicinal ash (bhasma). This essential step in Ayurveda ensures that the resulting preparations align with desired therapeutic outcomes. In preparing Nagabhasma, repeating putapaka enhances the product's efficacy and safety for patient use.
30) Amadosha (Āmadoṣa, Ama-dosha):
Amadosha represents the imbalances and toxic accumulation associated with disease states, particularly in diabetes. Ayurvedic principles aim to address and rectify amadosha by using therapeutic formulations like Nagabhasma. Understanding and rectifying amadosha is critical for achieving comprehensive disease management and maintaining overall health.
31) Toxicity:
Toxicity refers to the harmful effects a substance can have, particularly in medicinal contexts. In Ayurveda, understanding and mitigating toxicity through thorough purification processes like sodhana and marana is essential. The evolution of preparations like Nagabhasma exemplifies how ancient practices aim to convert toxic inputs into safe therapeutic agents.
32) Nirgundi (Nirguṇḍī, Nirgumdi):
Nirgundi, or Vitex negundo, is an important medicinal herb in Ayurveda used for its anti-inflammatory and analgesic properties. It is often included in kvatha preparations during the purification of metals like Naga. The incorporation of Nirgundi underlines the synergistic approach in Ayurvedic practices that combines herbs with minerals.
33) Haridra (Hāridra, Haridrā):
Haridra, or turmeric, is renowned in Ayurveda for its myriad health benefits, including its anti-inflammatory and antioxidant properties. When utilized in the preparation of bhasmas, Haridra enhances the purification process and contributes to the therapeutic attributes of products like Nagabhasma, showcasing the importance of incorporating well-known herbs in formulations.
34) Kashaya (Kāṣāya, Kāśaya, Kāsāya, Kaṣāya, Kaśāya, Kāsaya, Kaṣāyā, Kasāya, Kasaya):
Kashaya refers to the astringent taste attributed to many medicinal herbs in Ayurveda. It's crucial in balancing dosha and promoting overall health. This taste profile assists with metabolic functioning and is often considered during the creation of formulations like Nagabhasma, which aim to improve health parameters including sugar metabolism.
35) Yantra (Yamtra):
Yantra denotes the apparatus or apparatus used in Ayurvedic preparations, especially concerning the processes of purification and transformation. In the context of Nagabhasma, specialized yantras like 'pitara' are employed during the sodhana process to ensure optimal heating and quenching, thereby enhancing the quality and safety of the final product.
36) Sharava (Sarāva, Śarāva, Sarava, Śaravā, Sārava):
Sarava signifies a type of container used in Ayurvedic processes to encase materials during their preparation. This approach protects the integrity of formulations like Nagabhasma during intense heating and cooling cycles, ensuring that the properties are preserved while optimizing their therapeutic efficacy in treating conditions like diabetes.
37) Anjana (Añjana, Anjanā, Añjanā, Āñjana, Amjana, Anjāna):
Anjana is a reference to the authors of the study, indicating the collaborative efforts among researchers in the field of Ayurvedic medicine. This team approach highlights the importance of integrating knowledge from various disciplines to develop and validate traditional medicinal practices, including the preparation and application of Nagabhasma.
38) Mutra (Mūtra):
Mutra refers to urine in Ayurvedic terminology, bearing significance in diagnosing conditions like diabetes. In the discussed clinical study, the evaluation of urine constituents provides insight into the overall health and metabolic condition of patients. Thus, monitoring mutra helps to assess the effectiveness of treatments like Nagabhasma.
39) Jara (Jāra, Jarā, Jará):
Jara pertains to the aging or degenerative process in Ayurvedic medicine, often associated with loss of vitality. In this context, the preparation of Sastiputa Nagabhasma emphasizes rejuvenation by merging processes that counteract jara effects, thereby promoting overall wellness and improving the quality of life for individuals managing diabetes.
40) Vasa (Vāsā, Vāsa, Vasā, Vaśā, Vasha):
Vasa, or Adhatoda vasica, is another important herb in Ayurveda, primarily noted for its respiratory benefits. In the context of Nagabhasma preparation, the kvatha made from Vasa aids in purifying Naga, illustrating the principle of combining herbal remedies with mineral processing to enhance the therapeutic properties of Ayurvedic treatments.