Pharmaceutico-analytical study of sindhuradya taila
Journal name: World Journal of Pharmaceutical Research
Original article title: Pharmaceutico-analytical study of sindhuradya taila
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
This page presents a generated summary with additional references; See source (below) for actual content.
Original source:
This page is merely a summary which is automatically generated hence you should visit the source to read the original article which includes the author, publication date, notes and references.
Ch. Sridurga, M. Prathyusha and G. Ramesh Babu
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Pharmaceutico-analytical study of sindhuradya taila
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr20231-26771
Copyright (license): WJPR: All rights reserved
Download the PDF file of the original publication
Summary of article contents:
Introduction
The study conducted by Ch. Sridurga et al. addresses the importance of standardizing Ayurvedic preparations to ensure their safety, efficacy, and quality in modern medicine. Ayurvedic drugs, while traditionally used in treating various ailments, must undergo scientific evaluation to establish their credibility. The specific focus of this research was on Sindhuradya taila, a formulation detailed in the classical text Rasa Tarangini, used for managing conditions like Vicharchika and Pama. Through organoleptic, physico-chemical, and chromatographic analyses, the researchers aimed to develop a comprehensive standard for this Ayurvedic preparation.
The Significance of Standardization
Standardization in Ayurveda is crucial for ensuring that herbal formulations maintain consistent chemical profiles and exhibit biological activity. The study outlines the various analytical parameters through which Sindhuradya taila was prepared and evaluated. By adhering to a standardized process, the research emphasizes the need for rigorous testing that includes not only the organoleptic characteristics but also physico-chemical properties, which are essential for quality assurance. The results indicate the formulation's stability, safety, and potential health benefits, essentially bridging the gap between traditional practices and contemporary scientific validation.
Pharmaceutical and Analytical Approach
Creating Sindhuradya taila involved a dual-phase methodology comprising pharmaceutical study and analytical assessment. The researchers carefully procured raw materials, such as Sarshapa taila and Haridra, and followed traditional preparation processes involving specific treatments like Shodhana and Kalka nirmana. The analytical phase included various tests such as determining the refractive index, acid value, saponification value, and iodine value. Additionally, the study utilized High-Performance Thin Layer Chromatography (HPTLC) to map the chemical composition of the formulation. These meticulous approaches contribute to developing a standard monograph that could serve future quality assessments of Sindhuradya taila.
Insights from Physico-Chemical Tests
The results from the various physico-chemical tests indicated valuable information about the formulation's stability and quality. For instance, the refractive index was found to be 1.479, suggesting low chances of rancidity, while the acid value of 3.236 indicated minimal spoilage potential. The saponification value of 173.5 mg/g reflected the presence of beneficial short- and medium-chain fatty acids, underscoring the formulation’s suitability for use. Furthermore, an iodine value of 81.12% v/w confirmed a balanced degree of unsaturation in the oil used, adding to the formula’s nutritional quality. Such detailed analysis is pivotal in establishing a reliable quality assurance framework for Ayurvedic medicines.
Conclusion
In conclusion, the study of Sindhuradya taila showcases the importance of analytical standardization in Ayurvedic formulations. By integrating traditional methods with modern scientific evaluation, the researchers provide a detailed synthesis of how Sindhuradya taila can be prepared and assessed. The findings aim to offer a foundational guideline for quality control, paving the way for broader acceptance of Ayurvedic practices in the global healthcare context. The proposal of a monograph for Sindhuradya taila not only validates its efficacy and safety but also contributes to the scientific community's evolving understanding of herbal medicine.
FAQ section (important questions/answers):
What is the purpose of the analytical study on Sindhuradya taila?
The study aims to establish the safety, efficacy, and quality of Sindhuradya taila using various analytical parameters, thereby providing a scientific basis for its use in Ayurvedic formulations.
What are the key ingredients used to prepare Sindhuradya taila?
Sindhuradya taila is prepared using Sarshapa taila, Kalka from Haridra and Arka patra, Girisindhura, Tuttha, and water, following the traditional preparation methods described in Rasa Tarangini.
What organoleptic properties were observed in the Sindhuradya taila?
The Sindhuradya taila was observed to have a dark green color, strong characteristic odor, unctuous texture, and a viscous liquid appearance, which indicates its proper preparation and quality.
What does the saponification value indicate about Sindhuradya taila?
The saponification value of 173.5 mg/g suggests that Sindhuradya taila contains a significant amount of fatty acids, indicating its potential stability and quality as an oil-based formulation.
How does the iodine value relate to Sindhuradya taila?
The iodine value of 81.12% v/w indicates the degree of unsaturation of the fats in Sindhuradya taila, which may affect its stability and therapeutic properties.
What is the significance of the loss on drying test?
The loss on drying value of 0.196% v/w indicates the moisture content in Sindhuradya taila, helping assess its stability, shelf life, and microbiological safety during storage.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Pharmaceutico-analytical study of sindhuradya taila”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Taila (Thaila):
The word 'Taila' refers to oils or fat preparations in Ayurveda, traditionally used for medicinal purposes. In the context of formulations like 'Sindhuradya taila', it serves as the base medium to extract active herbal principles, enhancing bioavailability and therapeutic efficacy for various ailments, particularly skin conditions.
2) Study (Studying):
The term 'Study' denotes an in-depth investigation or analysis carried out to gather scientific evidence regarding 'Sindhuradya taila'. This study involves both pharmaceutical practices and analytical methods, providing a comprehensive understanding of the formulation's properties, safety, efficacy, and quality, essential for modern Ayurvedic practices.
3) Kalka:
The term 'Kalka' refers to pounded or ground herbal mixtures used in Ayurvedic formulations. It is a critical component in 'Sindhuradya taila', serving to release the medicinal properties of herbs like 'Haridra' when combined with oils, thereby enhancing the formulation's therapeutic qualities and effectiveness.
4) Drug:
The word 'Drugs' encompasses various medicinal substances, including herbal and mineral components, used in Ayurveda. The study of 'Sindhuradya taila' involves analyzing these drugs' efficacy and safety, facilitating the establishment of quality standards that align with modern pharmaceutical practices.
5) Sarshapataila (Sarsapataila, Sarshapa-taila):
The term 'Sarshapa-taila' denotes mustard oil, a key ingredient in Ayurvedic formulations. Used as a carrier oil, it facilitates the extraction of active components from medicinal herbs and enhances the bioavailability of the active ingredients in formulations like 'Sindhuradya taila', making it an effective treatment.
6) Sarshapa (Sarsapa):
The word 'Sarshapa' refers to mustard, whose oil is utilized in Ayurvedic preparations. Its properties, including antifungal and antibacterial effects, contribute to the therapeutic efficacy of 'Sindhuradya taila', which targets various skin conditions. Its use exemplifies the integration of botanical ingredients in traditional medicine.
7) Tuttha:
The term 'Tuttha' relates to a particular mineral substance used in Ayurvedic medicine, specifically for purification (Shodhana). In 'Sindhuradya taila', its careful processing ensures the removal of impurities, facilitating the production of a safer and more effective medicinal oil for topical applications.
8) Rasa (Rasha):
The word 'Rasa' in this context signifies the essence or primary quality of substances in Ayurveda. It plays a crucial role in understanding the therapeutic actions of formulations like 'Sindhuradya taila', allowing practitioners to select ingredients based on their inherent properties for effective treatment.
9) Kalpana:
The term 'Kalpana' refers to the preparation or formulation process in Ayurvedic medicine. It encompasses various methods of creating herbal combinations that enhance therapeutic efficacy, as exemplified in the preparation of 'Sindhuradya taila', which involves meticulous procedures for optimal drug efficacy.
10) Haridra:
The word 'Haridra' denotes turmeric, a key ingredient in Ayurvedic formulations noted for its anti-inflammatory and antimicrobial properties. In 'Sindhuradya taila', 'Haridra' contributes significantly to the formulation's efficacy, particularly in treating skin ailments, showcasing Ayurveda's reliance on composite herbal ingredients.
11) Arkapatra (Arka-patra):
The term 'Arka-patra' refers to the leaves of the calotropis plant, which are used in formulating 'Kalka'. This ingredient helps to release active medicinal components into the oil, thereby enhancing the overall effectiveness of 'Sindhuradya taila' in treating various ailments, particularly skin disorders.
12) Shodhana (Sodhana):
The word 'Shodhana' means purification, a critical step in Ayurvedic medicine that involves processing raw materials to remove impurities. This procedure ensures that the ingredients in 'Sindhuradya taila' are safe and effective, adhering to traditional principles while aligning with modern quality standards.
13) Patra:
The term 'Patra' translates to 'leaf' in Ayurveda, often denoting plants used in various formulations. In 'Sindhuradya taila', 'Arka patra' contributes not only to the medicinal properties of the oil but also defines the herbal source utilized in traditional treatments for skin conditions.
14) Arka:
The term 'Arka' refers to a plant commonly used in Ayurvedic medicine, particularly in the preparation of medicinal pastes and oils. Its inclusion in 'Sindhuradya taila' represents Ayurveda's holistic approach, where synergistic effects from various herbs enhance therapeutic outcomes for patients.
15) Paka:
The word 'Paka' signifies cooking or processing in Ayurveda, essential to preparing medicinal formulations. In the context of 'Sindhuradya taila', cooking the mixture allows proper integration of active herbal components, yielding a product that is therapeutically potent and aligns with Ayurvedic principles of medicine preparation.
16) Bhaishajya (Bhaisajya):
The term 'Bhaishajya' means medicine in Sanskrit and reflects the medicinal aspect of formulations like 'Sindhuradya taila'. This highlights the importance of quality, efficacy, and safety in Ayurvedic practice, ensuring that the formulation meets therapeutic needs while adhering to traditional principles.
17) Quality:
The phrase 'The quality' in this context underscores the importance of verifying and validating the effectiveness, safety, and consistency of medicinal products. For 'Sindhuradya taila', rigorous quality assessment ensures the formulation meets therapeutic claims and is suitable for use in modern healthcare.
18) Ayurveda (Ayus-veda):
The term 'Ayurveda' represents a traditional system of medicine originating from India, emphasizing balance between body, mind, and spirit. The study of 'Sindhuradya taila' exemplifies Ayurveda's holistic approach to health, integrating ancient wisdom with modern scientific methods to validate efficacy and safety.
19) Tirupati (Thirupati, Tiruppati):
The word 'Tirupati' indicates a geographical location in Andhra Pradesh, India, significant for traditional Ayurvedic practices. The local resources and knowledge contribute to the preparation of 'Sindhuradya taila', reflecting regional variations and the cultural heritage associated with Ayurvedic medicine in this area.
20) Bhavana (Bha-vana):
The term 'Bhavana' relates to a specific preparation technique in Ayurveda involving the maceration or processing of herbs to enhance their therapeutic properties. In 'Sindhuradya taila', this technique ensures that efficacy is maximized, emphasizing the meticulous nature of Ayurvedic formulations.
21) Heating:
The word 'Heating' signifies a crucial process in the preparation of Ayurvedic medicated oils like 'Sindhuradya taila'. Proper heating facilitates the extraction and integration of active compounds from herbs into the oil, ensuring that the final product exhibits the desired medicinal properties and stability.
22) Nature:
The phrase 'The nature' refers to the intrinsic properties of components within Ayurvedic formulations. Understanding 'The nature' of ingredients like 'Sarshapa' is crucial for predicting their behavior and interactions in 'Sindhuradya taila', guiding effective treatment approaches based on their characteristics.
23) Sneha:
The term 'Sneha' translates to 'oily' or 'unctuous' in Ayurveda, referring to the therapeutic quality of oils. In 'Sindhuradya taila', 'Sneha' properties enhance the absorption and efficacy of the active ingredients, playing a key role in the formulation's effectiveness for skin ailments.
24) Rasashastra (Rasa-shastra, Rasasastra):
The term 'Rasa-shastra' pertains to a specialized field within Ayurveda concentrating on the preparation and application of medicinal substances, particularly derived from metals and minerals. This knowledge is key in developing formulations like 'Sindhuradya taila', ensuring adherence to traditional practices while meeting contemporary scientific standards.
25) Developing:
The word 'Developing' signifies the process of creating or formulating new standards or methodologies. In the context of 'Sindhuradya taila', developing comprehensive analytical protocols ensures consistent quality and safety, aligning traditional preparation methods with the needs of modern pharmacological standards.
26) Substance:
The phrase 'The substance' refers to the specific materials or components used in formulations like 'Sindhuradya taila'. Understanding the nature of 'The substance' allows for better formulation strategies, ensuring the resulting product is effective, safe, and aligned with traditional preparation principles.
27) Shastra (Sastra):
The word 'Shastra' signifies a body of knowledge or science, which is foundational to various disciplines within Ayurveda. Understanding 'Shastra' is crucial in formulating 'Sindhuradya taila', ensuring that preparation methods adhere to traditional guidelines while incorporating modern scientific rigor.
28) Jala:
The term 'Jala' denotes water, a significant ingredient in many Ayurvedic formulations, including 'Sindhuradya taila'. Its role facilitates the proper preparation of herbal mixtures and aids in achieving the desired consistency and effectiveness of the final product, emphasizing Ayurveda's holistic approach to therapy.
29) Performance:
The word 'Performance' refers to the efficacy and effectiveness of a medicinal formulation in delivering therapeutic outcomes. In 'Sindhuradya taila', analyzing its 'Performance' through various tests helps determine how well it meets the intended health benefits, bolstering confidence in Ayurvedic medicine.
30) Measurement:
The term 'Measurements' signifies the quantitative assessments of various parameters in medicinal formulations. Accurate 'Measurements' in the study of 'Sindhuradya taila' ensure reliability in analytical results, fostering a foundation of evidence that supports the formulation’s safety and therapeutic effectiveness.
31) Science (Scientific):
The word 'Scientific' pertains to the methodical approach involving observation, experimentation, and analysis. In the context of 'Sindhuradya taila', applying scientific principles to traditional formulations enhances reliability, establishes evidence-based practices, and addresses the modern demand for validated medicinal products in healthcare.
32) Matulunga (Matulumga, Matulamga):
The term 'Matulunga' refers to citron or lemon, which is used in Ayurvedic medicine, particularly for purification processes. In the preparation of 'Sindhuradya taila', 'Matulunga' is utilized in Shodhana, ensuring that the raw ingredients undergo necessary processing to enhance their safety and efficacy.
33) Lakshana (Laksana):
The word 'Lakshana' denotes characteristics or traits within Ayurvedic formulations. Understanding the 'Lakshana' of 'Sindhuradya taila' is essential for recognizing its therapeutic profile and efficacy, guiding practitioners in the appropriate application and use of the formulation in treating skin conditions.
34) Medicine:
The term 'Medicines' encompasses various formulations designed for therapeutic purposes. In the context of Ayurveda, 'Medicines' like 'Sindhuradya taila' represent holistic solutions, combining herbal, mineral, and transformative practices to address health needs while promoting wellness and balance.
35) Ardraka:
The term 'Ardraka' refers to ginger, a commonly used herb in Ayurvedic practice. Its incorporation in the preparation of 'Sindhuradya taila' contributes additional medicinal properties, enhancing the overall therapeutic potential of the formulation against skin ailments and exemplifying the use of botanicals in treatment.
36) Andhra (Amdhra):
The word 'Andhra' denotes the Indian state of Andhra Pradesh, known for its rich Ayurvedic heritage. The availability of local herbs and climatic conditions influences the preparation of formulations like 'Sindhuradya taila', reflecting the cultural practices and traditional medicinal knowledge of the region.
37) Khara:
The term 'Khara' signifies dry or strong in Ayurveda, often used to describe the quality of processed oils. In the context of 'Sindhuradya taila', achieving 'Khara' state through careful processing ensures enhanced stability and effectiveness of the formulation in therapeutic applications.
38) India:
The word 'India' represents the origin of Ayurveda as a traditional healing system. The study of 'Sindhuradya taila' within this cultural context emphasizes the integration of ancient wisdom with modern scientific validation, highlighting Ayurveda's relevance in contemporary health practices worldwide.
39) Table:
The term 'Table' denotes a systematic arrangement of data used to present results clearly, aiding in the analysis of 'Sindhuradya taila' preparation outcomes. These tables summarize experimental measurements, facilitating interpretation and supporting conclusions drawn from the analytical study of the formulation.
40) Yama:
The word 'Yama' signifies a traditional measure of time or discipline within Ayurveda. In the context of the preparation of 'Sindhuradya taila', understanding 'Yama' helps establish the duration of critical processes, ensuring that proper techniques are followed for optimal quality and therapeutic efficacy.
41) Pama (Pama°):
The term 'Pama' refers to skin conditions or diseases in Ayurvedic terminology. 'Sindhuradya taila' serves as a therapeutic formulation to alleviate issues like 'Vicharchika' and 'Pama', showcasing Ayurveda's approach to treating ailments through the use of herbal and mineral combinations.
42) Fire:
The word 'Fire' denotes a crucial element in Ayurvedic medicine for cooking or processing ingredients. In preparing 'Sindhuradya taila', controlled 'Fire' ensures proper heat application, which is vital for extracting and integrating active components from herbs, ultimately impacting the formulation's efficacy.
43) Discussion:
The word 'Discussion' refers to the analytical dialogue about the study findings related to 'Sindhuradya taila'. Engaging in 'Discussion' allows researchers to interpret results, compare with existing knowledge, and advance understanding of the formulation's properties while exploring implications for practice.
44) Karnataka:
The word 'Karnataka' signifies a state in India known for its rich tradition in Ayurveda. The study of 'Sindhuradya taila' within this geographical context highlights the regional practices, various herbal resources available, and contributes to a broader understanding of Indian medicinal traditions.
45) Kharapaka:
The term 'Kharapaka' refers to a specific stage in Ayurveda, indicating the appropriate dryness of medicated oils. Achieving 'Kharapaka' in 'Sindhuradya taila' ensures that the formulation reaches optimal therapeutic effectiveness, showcasing the significance of precise processing in traditional medicine.
46) Knowledge:
The word 'Knowledge' denotes the body of understanding gained through study and experience. In 'Sindhuradya taila', the accumulation of 'Knowledge' about preparation techniques, ingredient properties, and therapeutic benefits illustrates the integration of traditional wisdom with modern scientific inquiry in Ayurveda.
47) Sindhura (Simdhura):
The word 'Sindhura' refers to a specific mineral, typically used in Ayurvedic formulations for its purported health benefits. Its inclusion in 'Sindhuradya taila' contributes to the formulation’s efficacy against certain skin ailments, demonstrating Ayurveda's integration of minerals within therapeutic products.
48) Activity:
The term 'Activity' in a pharmaceutical context refers to the effectiveness of a substance in producing a desired therapeutic result. Analyzing the 'Activity' of 'Sindhuradya taila' ensures that the formulation meets intended healthcare goals and validates its use in Ayurvedic practice.
49) Relative:
The word 'Relative' signifies a comparative aspect, often indicating relationships between various factors or properties within the study. In the context of 'Sindhuradya taila', understanding 'Relative' differences in measurements can provide insights into formulation stability and effectiveness among different samples.
50) Chennai:
The word 'Chennai' references a major city in India known for its markets where medicinal substances like 'Girisindhura' can be sourced. The availability of such ingredients influences the formulation of 'Sindhuradya taila', reflecting the city's role in traditional medicine supply chains.
51) Dravya:
The term 'Dravya' refers to substances or materials utilized in medicinal preparations. In the study of 'Sindhuradya taila', understanding the properties and characteristics of each 'Dravya' supports the development of a high-quality formulation, essential for its therapeutic efficacy and safety.
52) Medium:
The word 'Medium' refers to the vehicle or base used to administer medicinal properties. In 'Sindhuradya taila', oils serve as a 'Medium' for extracting herbal components, enhancing the overall effectiveness and absorption of the formulations in treating various ailments.
53) Water:
The term 'Water' signifies an essential ingredient in many Ayurvedic formulations. In 'Sindhuradya taila', 'Water' plays a role in the preparation process, facilitating the extraction and amalgamation of active ingredients, thus ensuring the formulation achieves its desired therapeutic properties.
54) Lemon:
The word 'Lemon' denotes a fruit that is utilized as a natural agent for purification purposes in Ayurveda. In the context of 'Sindhuradya taila', 'Lemon' is employed during the Shodhana process of 'Tuttha', ensuring the removal of impurities and enhancing the safety of the formulation.
55) Giri:
The term 'Giri' refers to a type of mineral or herbal material used in Ayurvedic formulations. In 'Sindhuradya taila', sourcing quality 'Giri' from reliable locations emphasizes the significance of selecting high-quality ingredients to ensure the formulation's therapeutic effectiveness.
56) Babu:
The term 'Babu' typically denotes a respectful address in India, here referring to one of the authors involved in the study of 'Sindhuradya taila'. This signifies the collaborative nature of research and the importance of authorship in the academic validation of Ayurvedic preparations.
57) Line:
The word 'Line' denotes a progression or method, particularly in referencing the established protocols or guidelines followed in Ayurvedic formulations. In 'Sindhuradya taila', adherence to 'Line' of traditional practice ensures that the preparation meets expected standards of efficacy and safety.
58) Hand:
The term 'Hand' signifies the manual process involved in preparing Ayurvedic formulations. In the context of 'Sindhuradya taila', skilled hands are instrumental in executing precise preparation techniques, highlighting the importance of traditional craftsmanship in the formulation of effective medicinal products.
59) Life:
The word 'Life' in this context relates to the holistic view of health and wellness in Ayurveda. 'Sindhuradya taila', as a part of this traditional system, aims to restore balance and promote 'Life' by addressing specific health issues through natural, therapeutic means.
60) Oil:
The word 'Oils' refers to lipid-based substances utilized in Ayurvedic formulations. In 'Sindhuradya taila', oils serve not only as carriers for active herbal properties but also provide therapeutic benefits themselves, further enhancing the formulation's effectiveness against various ailments, particularly skin conditions.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Pharmaceutico-analytical study of sindhuradya taila’. Further sources in the context of Science might help you critically compare this page with similair documents:
Shodhana, Tuttha, Kalka, Rasashastra, Analytical study, Bhaishajya kalpana, Loss on drying, High performance thin layer chromatography, Pharmaceutical Study, Sneha Kalpana, Refractive index, Saponification value, Iodine value, Acid value, High performance thin layer chromatography (HPTLC), Physico-chemical tests, Organoleptic test, Churna nirmana, Experimental data, Analytical standardization.