GC-MS analysis of ethanol extract from Securidaca longipedunculata leaves.
Journal name: World Journal of Pharmaceutical Research
Original article title: Gc-ms analysis and the establishment of mass spectrometric fingerprints of chemical constituents present in ethanol extract of securidaca longipedunculata leaves
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
This page presents a generated summary with additional references; See source (below) for actual content.
Original source:
This page is merely a summary which is automatically generated hence you should visit the source to read the original article which includes the author, publication date, notes and references.
Samuel E. Egga, Mbanefo M. Ekwenchi, Adams Theophilus, Chukuka Achuenu, Solomon D. Lokta
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Gc-ms analysis and the establishment of mass spectrometric fingerprints of chemical constituents present in ethanol extract of securidaca longipedunculata leaves
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr20234-27325
Copyright (license): WJPR: All rights reserved
Download the PDF file of the original publication
Summary of article contents:
Introduction
The study examines the ethanolic extract of Securidaca longipedunculata leaves, focusing on its phytochemical constituents through gas chromatography-mass spectrometry (GC-MS) analysis. Traditionally used in African medicine for various health issues, this plant is noted for its potential therapeutic properties. Despite its historical medicinal usage, there is limited scientific documentation on its phytoconstituents, prompting this research to uncover valuable bioactive agents that could benefit pharmaceutical, cosmetic, food, and agrochemical industries.
Phytochemical Composition Revealed by GC-MS
The GC-MS analysis revealed a total of 47 phytochemical compounds present in the ethanolic extract, including phenolic compounds, fatty acid derivatives, esters, and vitamin E. The identification of these components was based on their high matching scores with the NIST standard reference database. Among the phytoconstituents, notable compounds included Methyl palmitate, Oleic acid, and α-Tocopherol, suggesting the extract’s potential as a rich source of bioactive compounds with significant medicinal properties.
Bioactive Properties and Medicinal Applications
The identified phytochemicals highlight the antioxidant properties of Securidaca longipedunculata, which may explain its traditional use in treating various ailments. The presence of secondary metabolites such as phenolics and fatty acids aligns with previous studies documenting their biological activities, including anti-inflammatory and antimicrobial effects. These findings support the notion that S. longipedunculata could serve as an effective medicinal alternative in addressing conditions like sexual infections and respiratory ailments.
Implications for Future Research
Despite the promising results, the study emphasizes the need for further investigations into the isolation and evaluation of the biological activities of Securidaca longipedunculata. Comprehensive pharmacological studies are necessary to validate its traditional uses and explore its potential applications in various industries. By understanding the therapeutic mechanisms and safety profile of these phytochemicals, researchers can pave the way for developing new drugs derived from this plant.
Conclusion
The study successfully identifies seventeen phytoconstituents from the ethanolic extract of Securidaca longipedunculata leaves, emphasizing the plant’s potential medicinal value corroborated by traditional practices. With its phytochemicals demonstrating useful biological activities, this research underscores the importance of exploring indigenous plants as sources of new therapeutic agents. Further studies, including antimicrobial and antioxidant evaluations, could lead to significant advancements in the use of Securidaca longipedunculata in modern medicine and industry.
FAQ section (important questions/answers):
What is the main focus of the study on Securidaca longipedunculata?
The study evaluates the phytoconstituents in the ethanolic extract of Securidaca longipedunculata leaves using GC-MS analysis, identifying various bioactive compounds that may have medicinal applications.
What extraction method was used for the leaves in the study?
The leaves were subjected to maceration in absolute ethanol for 92 hours at room temperature, followed by filtration and evaporation to concentrate the extract.
What types of compounds were identified in the ethanol extract?
The GC-MS analysis revealed various phytoconstituents, including phenolics, phthalates, fatty acid derivatives, esters, and vitamin E among the compounds present in the leaves extract.
Why is Securidaca longipedunculata significant in traditional medicine?
This plant has a history of use in African traditional medicine to treat various ailments, such as sexual infections, pain, and microbial infections, highlighting its potential therapeutic value.
What are the next steps suggested for this research?
Further isolation and biological evaluation of the identified compounds are necessary to explore the medicinal potential of Securidaca longipedunculata for applications in pharmaceutical and other industries.
How does the presence of these compounds support traditional medicinal use?
The identified phytochemical constituents in the study, such as fatty acids and phenolics, provide a scientific basis for the traditional medicinal applications of Securidaca longipedunculata.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “GC-MS analysis of ethanol extract from Securidaca longipedunculata leaves.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Phytochemical:
Phytochemicals are naturally occurring chemical compounds found in plants, often responsible for their color, flavor, and disease resistance. They are of significant interest in medicine due to their potential health benefits, including anti-inflammatory, antioxidant, and anticancer properties, making them crucial in disease prevention and treatment methodologies.
2) Drug:
Drugs are substances that bring about physiological changes in the body. They are integral to medical treatment and patient care. The development of new drugs often involves extensive research, including the examination of plant-derived compounds, which have a rich history as effective therapeutic agents in diverse cultures.
3) Medicine:
Medicine encompasses the science and practice of diagnosing, treating, and preventing disease. It draws on various disciplines and methods, including pharmacology, biochemistry, and herbal medicine, some of which utilize phytochemicals from plants to create effective therapeutic agents aimed at improving health outcomes.
4) Study (Studying):
A study refers to an investigative research process aimed at discovering or analyzing specific phenomena. In the context of phytochemicals and medicinal plants, studies contribute to understanding their properties, efficacy, and potential applications in healthcare. Research findings can reveal new insights that further traditional medicinal practices.
5) Tree:
In botanical terms, a tree is a perennial plant with an elongated stem or trunk, branching at some height above the ground. Trees, alongside other plants, are valuable sources of medicinal compounds. Certain species, like Securidaca longipedunculata, are noted for their therapeutic uses in traditional medicine.
6) Oil:
Oils commonly refer to viscous substances derived from plants and other sources, utilized in cooking, cosmetic, and medicinal applications. In medicinal contexts, essential oils extracted from plants often possess therapeutic benefits, including anti-inflammatory and antimicrobial properties, and are used in various treatments and wellness practices.
7) Pharmacological:
Pharmacological research focuses on the study of drugs and their effects on biological systems. This field explores how natural and synthetic compounds interact with bodily functions, contributing to drug development, therapeutic strategies, and understanding the efficacy and safety of medicinal substances derived from plants and other sources.
8) Tuberculosis:
Tuberculosis (TB) is a serious infectious disease caused by airborne bacteria, primarily affecting the lungs but can spread to other organs. It poses a significant public health challenge, particularly in developing countries. Research involving phytochemicals highlights their potential in developing new treatments to combat TB effectively.
9) Science (Scientific):
Science refers to a systematic enterprise that builds and organizes knowledge in the form of explanations and predictions about the universe. In medicine, scientific inquiry drives the exploration and validation of natural remedies, paving the way for advancements in pharmaceutical applications derived from medicinal plants.
10) Species:
A species is a group of organisms sharing common characteristics and capable of interbreeding. The classification of plant species is vital for identifying those with medicinal value. Understanding the characteristics of specific species enables researchers to investigate their phytochemicals and potential health benefits.
11) Cancer:
Cancer is a group of diseases characterized by abnormal cell growth. It poses a major health challenge worldwide. Research into phytochemicals has revealed potential anticancer properties in certain plant extracts, prompting investigations into the role these natural compounds can play in therapeutic interventions against cancer.
12) Water:
Water is a vital organic compound, essential for all known forms of life. In the context of plant extractions, water can be used as a solvent to extract bioactive compounds, though organic solvents like ethanol are often preferred in phytochemical studies to obtain desired concentrations and specific properties.
13) Table:
A table is a systematic arrangement of data, typically in rows and columns, used for organizing and presenting information clearly. In scientific literature, tables are commonly used to summarize data from experiments, including the identification and quantification of phytochemicals derived from plant studies.
14) Food:
Food refers to any substance consumed to provide nutritional support for the body. Many medicinal plants are traditionally used as food and medicine, highlighting the nutritional and therapeutic values of phytochemicals. Certain phytochemical compounds found in food sources are studied for their health-promoting properties.
15) Family:
Family, in a botanical sense, refers to a major taxonomic category grouping together related plants. This classification is vital for identifying medicinal plants and understanding their potential therapeutic effects based on shared characteristics and related phytochemical profiles, aiding in research and application.
16) Antibiotic (Antibacterial):
Antibacterial refers to substances that combat bacterial infections. The increasing resistance of bacteria necessitates the search for new antibacterial agents, especially from natural sources. Numerous studies explore the antibacterial properties of phytochemicals derived from medicinal plants, highlighting their role in alternative treatment options.
17) Discussion:
In scientific literature, discussions analyze and interpret research findings, elucidating their implications and potential applications. This section contextualizes results within the broader field of study, addressing how identified phytochemicals may influence health outcomes and contribute to traditional medicine practices.
18) Pesticide:
A pesticide is a type of chemical meant to manage pests in agriculture. Research into plant-derived phytochemicals often investigates their efficacy as natural pesticides. Compounds extracted from medicinal plants can serve as effective alternatives to synthetic pesticides, promoting sustainable agricultural practices.
19) Flavonoid:
A flavonoid is a specific type of flavonoid compound, often recognized for its role in plant pigmentation and health benefits. These compounds have been studied for their potential effects against diseases such as cancer and cardiovascular disorders, making them of great interest within pharmacological research.
20) Container:
A container is an object that holds other items or substances. In laboratory settings, various containers are used for storing samples, extracts, and chemicals during research. Proper containment ensures the integrity and safety of samples being analyzed for phytochemical composition and biological activity.
21) Toxicity:
Toxicity refers to the degree to which a substance can harm living organisms. Assessing the toxicity of phytochemicals is vital to ensure safety for medicinal use. Studies often evaluate both the therapeutic benefits and potential toxic effects of plant extracts to determine their viability in treatment.
22) Activity:
Activity, in a scientific context, refers to the effects or actions of substances, particularly regarding biological responses. The activity of phytochemicals is assessed to understand their efficacy in medicinal applications, influencing developments in drugs and treatments derived from natural plant sources.
23) Epilepsy:
Epilepsy is a neurological disorder characterized by recurring seizures. Traditional medicine often includes herbal remedies for managing epilepsy symptoms. Research into phytochemicals could uncover plant-based compounds with anticonvulsant properties, presenting opportunities for developing new treatments for patients with this condition.
24) Disease:
A disease is a dysfunction of the body's normal biological processes, often requiring medical intervention. Many medicinal plants are researched for their phytochemical constituents to discover potential treatments or preventative measures for various diseases, leveraging traditional knowledge alongside modern scientific methodologies.
25) Medium:
Medium commonly refers to a substance or environment used for various processes, including growth, extraction, or analysis. In laboratories, different media can be utilized to cultivate microorganisms or to dissolve phytochemicals from plant materials, impacting the yield and analytical outcomes of experiments.
26) Powder:
Powder refers to a dry, solid substance composed of finely dispersed particles. In herbal medicine, powdered plant extracts are commonly used for their phytochemical content. The process of grinding dried plant materials into powder helps in easier extraction and administration of active compounds for therapeutic purposes.
27) Fever:
Fever is an elevation in body temperature often indicative of infection or illness. Many traditional medicinal plants have been utilized to relieve fever symptoms. The study of their phytochemicals may reveal compounds with antipyretic properties, contributing to the development of effective treatments for fever.
28) Fire:
Fire refers to the combustion process that produces heat and light. In ecological contexts, fire can cause significant changes in plant communities. The understanding of fire resistance in plant species may influence the choice of medicinal plants based on their resilience and potential for continued therapeutic application despite environmental challenges.
29) Pain:
Pain is an unpleasant physical sensation that may signal injury or illness. Numerous plants used in traditional medicine are explored for their analgesic properties. Phytochemicals found in these plants might alleviate pain, leading to the development of safer, natural alternatives to conventional pain relief medications.
Other Science Concepts:
Discover the significance of concepts within the article: ‘GC-MS analysis of ethanol extract from Securidaca longipedunculata leaves.’. Further sources in the context of Science might help you critically compare this page with similair documents:
Medicinal plant, Pharmaceutical industries, Antioxidant property, Secondary metabolite, Medicinal potential, Voucher specimen, Extraction method, GC-MS analysis, Medicinal application, Gas Chromatography Mass Spectrometry, Fatty acid, Traditional Medicine Practitioner, Phytochemical component, Food industry application.