Phytochemicals and pharmacological effects of Abroma augusta Linn.
Journal name: World Journal of Pharmaceutical Research
Original article title: A review of the phytochemical constituents and pharmacological activities of abroma augusta linn.
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Jyoti K. Soundarmal, S. D. Tupkar, Dr. K. R. Biyani, Shrutika M. Ruptakke
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: A review of the phytochemical constituents and pharmacological activities of abroma augusta linn.
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr20235-27558
Copyright (license): WJPR: All rights reserved
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Summary of article contents:
Introduction
Abroma Augusta L., commonly referred to as Devil's cotton, is a medicinal plant belonging to the Malvaceae family, predominantly found in tropical regions of Asia, Africa, and Australia. This plant is utilized in folk medicine for various ailments, with almost all its parts—leaves, roots, root bark, stem bark, seeds, and heartwood—having therapeutic applications. The extracts of Abroma Augusta are recognized for their pharmacological properties, which include anti-inflammatory, wound healing, hypolipidemic, and antimicrobial activities, among others. The objective of the study reviewed is to provide a scientific basis for the folkloric use of this plant and to evaluate its phytochemical constituents that contribute to its pharmacological efficacy.
Pharmacological Properties and Phytochemical Analysis
One significant aspect of Abroma Augusta is its wide range of pharmacological activities. Different parts of the plant display therapeutic potentials including anti-inflammatory, wound healing, and hypolipidemic effects. The presence of phytochemicals such as flavonoids, alkaloids, and phenolics has been confirmed through phytochemical analysis. Notably, the methanolic extract of the plant has shown potent anti-inflammatory effects when compared to standard medications like diclofenac sodium. Additionally, the plant's ability to aid in wound healing is well-documented, highlighting its traditional use.
Gynecological Applications
Abroma Augusta is particularly noteworthy for its applications in treating gynecological disorders. The ethanolic extracts from the leaves and stems of the plant are utilized for addressing menstrual issues such as dysmenorrhea and amenorrhea. Furthermore, the root powder acts as an anti-abortifacient and fertility agent. Research indicates that the extracts exhibit contractile effects on the uterus, providing therapeutic benefits for women experiencing various menstrual disorders. This traditional knowledge aligns with scientific findings, reinforcing the plant's value in gynecology.
Antimicrobial and Antioxidant Effects
Another critical aspect of Abroma Augusta is its antimicrobial and antioxidant properties. The extracts derived from its seeds exhibit significant antibacterial and antifungal activities against various pathogens. In addition, the methanolic extract has demonstrated strong antioxidant capabilities, which may contribute to cellular protection and overall health improvement. The combination of Abroma Augusta with other herbs, like Curcuma longa, has shown synergistic effects in enhancing antioxidant activities, underscoring its potential in integrated herbal therapies.
Conclusion
The comprehensive review of Abroma Augusta L. reveals it as a medicinal powerhouse with diverse pharmacological activities, ranging from anti-inflammatory to antimicrobial effects, as well as its application in gynecology. The plant is rich in beneficial phytochemical constituents that validate its traditional uses in various health issues. As research continues to uncover the depth of its capabilities, Abroma Augusta holds promise for future therapeutic developments, particularly in managing chronic conditions like diabetes. Overall, it is vital to further investigate the active compounds within this plant to harness its full potential in modern medicine.
FAQ section (important questions/answers):
What is Abrima Augusta and its common names?
Abrima Augusta, known as Ulatkambal in Hindi and Devil's cotton in English, is a medicinal plant primarily used for treating menstrual disorders, diabetes, and wound healing.
What pharmacological activities are associated with Abrima Augusta?
Abrima Augusta exhibits various pharmacological activities including anti-inflammatory, wound healing, hypolipidemic, antioxidant, antimicrobial, antidiabetic, and thrombolytic effects.
Which parts of Abrima Augusta are used for medicinal purposes?
All parts of Abrima Augusta, including leaves, roots, bark, seeds, and heartwood, are utilized for treating various ailments.
What phytochemical compounds are found in Abrima Augusta?
The plant contains flavonoids, phenolics, alkaloids, steroids, and triterpenes among other compounds.
How does Abrima Augusta contribute to gynecological health?
The plant is used in treating menstrual disorders, infertility, and acts as an abortifacient.
What evidence supports the medicinal effectiveness of Abrima Augusta?
Studies indicate various pharmacological activities of Abrima Augusta, proving its efficacy for several health conditions.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Phytochemicals and pharmacological effects of Abroma augusta Linn.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Activity:
Activity refers to the biological effects that a substance or extract has on living organisms. In the context of Abroma Augusta, various pharmacological activities such as anti-inflammatory, antioxidant, and hypolipidemic effects illustrate how its constituents can influence health and therapeutic outcomes, validating its use in traditional medicine.
2) Cotton:
Cotton, specifically in this context, refers to 'Devil's Cotton', the common name for Abroma Augusta. This nomenclature is derived from its fibrous, cotton-like seed fibers. The plant has cultural significance and uses in traditional medicine, hence its name evokes the image of a plant used for various health benefits.
3) Pharmacological:
Pharmacological pertains to the study of the effects of drugs and their mechanisms in the body. It is relevant here as the text discusses the pharmacological activities of Abroma Augusta, exploring how its compounds can affect biological systems, showcasing both therapeutic potentials and actions against specific diseases.
4) Rat:
Rats are commonly used in scientific research as model organisms due to their biological similarities to humans. In this study, Wistar rats are utilized to evaluate the anti-inflammatory and other pharmacological effects of Abroma Augusta extracts, allowing researchers to infer potential efficacy and safety in human applications.
5) Phytochemical:
Phytochemicals are natural bioactive compounds found in plants that contribute to their medicinal properties. The relevance of phytochemical analysis in the document lies in identifying active constituents in Abroma Augusta, such as flavonoids and alkaloids, which are responsible for its various therapeutic claims and traditional uses.
6) Flavonoid:
Flavonoid, in singular form, represents any specific member of the flavonoid family. These compounds are noted for their health-promoting properties, and the study emphasizes their role in Abroma Augusta, adding depth to its pharmacological profile by examining the individual contributions of different flavonoids found in the plant.
7) Water:
Water is a universal solvent and plays a critical role in biological systems. In this study, distilled water is used as a negative control during clot lysis assessment. It underscores the contrast in efficacy between natural extracts and standard treatments, emphasizing the importance of controls in pharmacological research.
8) Beta:
Beta refers to a specific chemical structure or compound form, such as Beta-sitosterol found in Abroma Augusta. This phytosterol is significant for its cholesterol-lowering effects among other health benefits, showcasing its potential as a therapeutic agent and linking its existence to the plant's traditional uses for ailments.
9) Pain:
Pain denotes physical suffering or discomfort that could arise from injury or illness. The role of Abroma Augusta in treatment is highlighted by its reported analgesic properties, which provide a pharmacological basis for its traditional use in managing pain and inflammatory conditions, making it a valuable medicinal resource.
10) Curcuma longa:
Curcuma longa, commonly known as turmeric, is a plant renowned for its medicinal properties, particularly its anti-inflammatory effects. The text explores its synergy with Abroma Augusta, illustrating how combining these two plants may enhance therapeutic effects in treating conditions like diabetes, thus supporting holistic medicinal practices.
11) Dysmenorrhea (Dysmenorrhoea):
Dysmenorrhea refers to painful menstrual cramps that many women experience during their menstrual cycle. Abroma Augusta's traditional use as a remedy for dysmenorrhea demonstrates its relevance in gynecological health and highlights the necessity of further pharmacological research to validate and understand this use in treating menstrual disorders.
12) Disease:
Disease, in singular form, refers to an individual pathological condition. The text emphasizes the broad spectrum of conditions that Abroma Augusta is believed to affect, encouraging further study into its active compounds to validate traditional claims and potentially discover new therapeutic applications.
13) Powder:
Powder refers to the ground form of a substance, often used in herbal medicine for ease of consumption or for extraction purposes. Abroma Augusta is noted for its powdered form's medicinal uses, emphasizing the value of traditional preparations in delivering the plant's therapeutic effects for various ailments.
14) Study (Studying):
Study refers to a systematic investigation to gain knowledge or verify facts. In this context, it pertains to the evaluation of the pharmacological activities of Abroma Augusta. Rigorous studies are essential to substantiate folk medicine claims and develop evidence-based applications in modern pharmacology and healthcare.
15) Azadirachta indica:
Azadirachta indica, known as neem, is a tree noted for its medicinal properties. The text discusses its combination with Abroma Augusta in antidiabetic treatment, highlighting the significance of polyherbal formulations in traditional medicine, showcasing the synergistic potential of combining multiple plant extracts for enhanced therapeutic benefits.
16) Pharmacology:
Pharmacology is the science of drugs and their interactions with biological systems. The relevance of this field in the document is clear, as it underpins the investigation of Abroma Augusta's extracts and their pharmacological activities, illustrating the bridge between traditional knowledge and scientific validation of herbal medicine.
17) Inflammation:
Inflammation is the body's response to injury or infection, manifesting as swelling, redness, and pain. The text highlights the anti-inflammatory activities of Abroma Augusta as critical for its understanding and therapeutic applications, emphasizing the importance of exploring herbal remedies for managing inflammatory conditions commonly faced by individuals.
18) Leucoderma:
Leucoderma, commonly associated with vitiligo, is characterized by patches of skin losing their pigment. The relevance lies in Abroma Augusta's folk use for this condition, and the studies cited highlight the potential for phytochemicals in the plant to address skin disorders, necessitating further research in dermatological applications.
19) Substance:
Substance, in singular form, denotes an individual material with unique chemical and physical properties. The study explores substances within Abroma Augusta that contribute to its pharmacological effects, emphasizing the need for detailed chemical profiling in herbal research to accurately attribute therapeutic actions to specific plant constituents.
20) Augustus:
Augustus likely refers to Abroma Augusta, the focus of the text. This designation highlights the significance of the species name in botanical classification and its association with various folkloric and medicinal practices, underlining the need for continued exploration into its biochemical and pharmacological profiles.
21) Medicine:
Medicine encompasses the science and practice of diagnosing, treating, and preventing disease. The relevance in this context stems from Abroma Augusta's role in traditional medicine systems, where it has been used for various ailments, necessitating rigorous studies to validate its therapeutic potential and integrate findings into contemporary medical practices.
22) Debility:
Debility refers to physical weakness, often due to illness or lack of strength. The document discusses Abroma Augusta's traditional use in addressing debility, highlighting its relevance in folk medicine as a remedy for fatigue or weakness, and supporting the need for empirical studies to assess its efficacy in this regard.
23) Species:
Species denotes a specific group of organisms capable of interbreeding. The text focuses on Abroma Augusta as a species of interest in pharmacology and traditional medicine, emphasizing the importance of understanding its biological characteristics and the therapeutic potential inherent in its chemical composition for medicinal applications.
24) Forest:
Forest refers to a large area covered chiefly with trees and undergrowth. Mentioning forests highlights the natural environment where Abroma Augusta thrives, pointing to ecological conservation and the importance of preserving plant species with medicinal value for future research and potential therapeutic discoveries.
25) Family:
Family refers to a taxonomic rank used in biological classification. In this text, it pertains to the Malvaceae family to which Abroma Augusta belongs, emphasizing the phylogenetic relationships among different plant species and their potential shared characteristics, particularly important in understanding their pharmacological similarities.
26) Animal:
Animal refers to multicellular organisms that are typically mobile and consume organic material. In pharmacological studies, animal models (like rats) are crucial for understanding the effects of plant extracts, such as Abroma Augusta, on biological systems, forming a basis for potential human applications and therapeutic development.
27) India:
India is a South Asian country rich in biodiversity, traditional practices, and herbal medicine. The text emphasizes Abroma Augusta's relevance within the Indian context, showcasing the integration of traditional knowledge into modern pharmacological research and illustrating the significance of indigenous plants in promoting health and wellness.
28) Hindi (Himdi):
Hindi is an Indo-Aryan language spoken predominantly in India. It is essential in the text as it signifies cultural relevance, particularly the local names such as 'Ulatkambal,' linking Abroma Augusta to its traditional use in Indian folk medicine, thereby emphasizing the rich linguistic and cultural heritage surrounding herbal practices.
29) Blood:
Blood is a vital fluid in the body responsible for transporting oxygen and nutrients. The text mentions diabetes and its treatment, signifying the relevance of managing blood glucose levels. Abroma Augusta's antidiabetic activities aim to improve overall health by influencing blood parameters, thus linking it to effective disease management.
30) Tree:
Tree is a perennial plant with a tall, woody stature. Mentioning 'tree' in the context of Abroma Augusta reflects its botanical nature, positioning it within a classification that underscores its ecological role and potential contributions to herbal remedies, inviting further investigation into its pharmacological properties and uses.
31) Cani:
Cani appears to be a typographical error, likely intending to reference a specific organism or a misspelling of 'canis'. Should it be 'canis,' this would relate to studies involving animal pathogens, linking back to the antimicrobial activities of Abroma Augusta and its relevance in vetinary medicines.
32) Pune:
Pune is a city in India known for its educational institutions and research facilities. The relevance of Pune in the text arises from the affiliations of authors associated with researching Abroma Augusta, exemplifying regional contributions to scientific studies and promoting traditional medicine within academia and modern healthcare.
33) Drug:
Drug refers to any substance used to diagnose, treat, or prevent disease. In this context, Abroma Augusta is positioned as a source of pharmacologically active compounds, potentially serving as a natural drug alternative in treating various health conditions, underscoring the importance of botanical research in drug development.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Phytochemicals and pharmacological effects of Abroma augusta Linn.’. Further sources in the context of Science might help you critically compare this page with similair documents:
Devil's cotton, Cultural significance, Chronic disease, Menstrual disorder, Wound healing, Clinical studies, Anti-inflammatory activity, Antioxidant activity, Pharmacological activities, Pharmacological activity, Experimental study, Hypolipidemic activity, Antimicrobial activity, Folk medicine, Antidiabetic activity, Folklore medicine, Dosage form, Gynecological disorder, Experimental rats, Thrombolytic activity, Wound healing activities, Diabetes treatment, Leaf extract, Tropical Asia, Root powder, Phytochemical constituent.