Standardization and solvent comparative study of abutilon hirtum l.

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Journal name: World Journal of Pharmaceutical Research
Original article title: Standardization and solvent comparative study of abutilon hirtum l.
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Author:

Gokulakrishnan S., Vaishnavi G. and K. B. Ilango


World Journal of Pharmaceutical Research:

(An ISO 9001:2015 Certified International Journal)

Full text available for: Standardization and solvent comparative study of abutilon hirtum l.

Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research

Doi: 10.20959/wjpr20235-27505

Copyright (license): WJPR: All rights reserved


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Summary of article contents:

Introduction

The study focuses on the medicinal plant Abutilon hirtum L., belonging to the Malvaceae family, known for its traditional therapeutic uses, including treatment of kidney gravel, diarrhea, cough, bladder inflammation, wounds, and as an antipyretic and diuretic. The research aims to standardize and evaluate this plant by comparing various solvents for extracting its beneficial compounds through both quantitative and qualitative methods. Different extraction processes, including maceration and Soxhlet extraction, were employed using multiple solvents, such as ethanol, methanol, acetone, and chloroform.

Extraction Methods and Their Importance

The research emphasizes the significance of extraction techniques in obtaining phytochemical constituents from Abutilon hirtum L. The study utilized maceration and Soxhlet extraction methods, examining each solvent's efficacy in extracting valuable compounds. The findings indicated that the choice of solvent greatly impacts the yield and variety of phytochemicals. Ethanol emerged as the most effective solvent, yielding a greater concentration of phytoconstituents, thus demonstrating the critical role of proper extraction methods in herbal medicine research.

Phytochemical Screening and Findings

Phytochemical analysis was conducted on the extracts to identify the presence of various secondary metabolites including alkaloids, flavonoids, saponins, tannins, and steroids. The qualitative tests revealed that different extracts showcased varied phytochemical profiles. For instance, the ethanolic extract was found to be rich in most phytoconstituents, while the chloroform extract showed lesser amounts. This comprehensive phytochemical profiling underscores the therapeutic potential of Abutilon hirtum L., opening avenues for further investigation into its medicinal properties.

Morphological and Physico-Chemical Characterization

The study also involved detailed morphological and physicochemical characterization of the leaves and roots of Abutilon hirtum L. The organoleptic properties were assessed, revealing greenish color and slight bitterness in the leaves. Physico-chemical parameters, including foreign matter, loss on drying, and ash values, were evaluated according to WHO guidelines, highlighting the quality and standardization metrics of the plant material. These insights are essential for ensuring the authenticity and safety of medicinal plant products.

Conclusion

In conclusion, the research on Abutilon hirtum L. offers valuable insights into its standardization and medicinal potential. The effective extraction methods employed establish a foundation for isolating specific bioactive compounds, which could be further explored for their therapeutic effects. The findings highlight the importance of rigorous characterization processes in validating the therapeutic claims of traditional herbal medicines. Future studies are warranted to isolate these phytochemicals and investigate their in vitro and in vivo activities, aiming to enrich the pharmacological understanding of this significant medicinal plant.

FAQ section (important questions/answers):

What is the primary aim of the study on Abutilon hirtum L.?

The study aims to describe and compare the best solvents used for the extraction of Abutilon hirtum L., as well as to standardize and evaluate its organoleptic, physical, and phytochemical properties.

How was the extraction of Abutilon hirtum L. conducted?

Extraction was done using the maceration method followed by Soxhlet extraction with various solvents, including ethanol, methanol, acetone, and chloroform, to identify the most effective solvent for obtaining phytoconstituents.

What phytochemicals were identified in Abutilon hirtum L.?

The phytochemical screening revealed the presence of alkaloids, carbohydrates, flavonoids, glycosides, tannins, saponins, and steroids among others, confirming the plant's medicinal potential.

Where was Abutilon hirtum L. collected for this research?

The leaves and roots of Abutilon hirtum L. were collected from Tirupur, Tamil Nadu, India, and authenticated by the Botanical Survey of India.

What methods were used for the qualitative analysis of the extracts?

Qualitative analysis involved standard procedures for identifying phytoconstituents using tests like Mayer's test and Dragendorff's test for alkaloids, as well as other assays for flavonoids and tannins.

What conclusions were drawn regarding the extraction solvents?

Ethanolic extracts of Abutilon hirtum L. were found to contain a higher concentration of phytoconstituents compared to extracts from methanol, acetone, or chloroform, indicating its effectiveness for extraction.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Standardization and solvent comparative study of abutilon hirtum l.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Drug:
'Drugs' encompass a range of substances with therapeutic properties, including both synthetic and natural origins. The study of plant-derived drugs is gaining momentum due to their perceived safety and efficacy, highlighting the importance of comprehensive research into their phytochemical profiles and medicinal benefits.

2) Water:
'The water' pertains to the solvent's role in herbal extraction processes. It is instrumental in dissolving water-soluble phytochemicals, thereby enabling effective extraction and subsequent analysis of the bioactive compounds present in plant materials.

3) Powder:
The word 'powder' denotes the processed form of plant materials, where dried leaves, roots, or stems are ground into a fine consistency. This powdered form is essential for standardization in herbal medicine, allowing for consistent dosing and effective extraction of medicinal constituents during formulation.

4) Phytochemical:
'Phytochemicals' are bioactive compounds produced by plants, often possessing health-promoting properties. Their study is crucial in evaluating the efficacy of herbal medicines, as these compounds can provide insights into the therapeutic potential of various plant extracts.

5) Activity:
'Activity' in pharmacology refers to the biological effects of a substance, particularly regarding its therapeutic potential. For instance, a medicinal plant's activity may be evaluated through its anti-inflammatory or analgesic properties, which are essential for understanding its application in traditional and modern medicine.

6) Science (Scientific):
'Scientific' denotes a methodical approach grounded in empirical research and experimentation. The scientific study of medicinal plants aims to validate traditional uses, provide evidence for effectiveness, and ensure safety through rigorous testing and analysis.

7) Flavonoid:
'Flavonoids' are a class of phytochemicals prevalent in many plants, recognized for their antioxidant and anti-inflammatory benefits. Their presence in herbal extracts contributes to the therapeutic potential of various plant-based medicines.

8) Surface:
The term 'surface' refers to the outer layer or coating of plant materials, especially leaves and roots. The texture and characteristics of the surface can influence extraction methods, as well as the bioavailability of active compounds during therapeutic use.

9) Table:
In research, a 'table' is a structured format for organizing data. Tables are employed to present experimental results, showing relationships between various parameters, such as phytochemical constituents and their corresponding biological activities, facilitating easy comprehension and analysis.

10) Disease:
'Diseases' are pathological conditions affecting health and well-being. Research into plant-based drugs focuses on their ability to combat various diseases, particularly through their active phytochemical constituents, thus providing alternative or complementary therapeutic options.

11) Indian:
'Indian' refers to the geographic and cultural context of India's rich traditional medicine system, wherein diverse flora is utilized for therapeutic purposes. Studies on plants like Abutilon hirtum highlight the significance of Indian medicinal practices in contemporary healthcare.

12) India:
'India' is notable for its extensive use of herbal medicine rooted in ancient traditions. The country's diverse biodiversity provides a rich source of medicinal plants, inviting scientific exploration into their pharmacological potential and contributions to public health.

13) Study (Studying):
'The study' refers to the specific research or investigation into herbal extracts, aiming to analyze and understand their pharmacological effects. It plays a pivotal role in exploring the potential therapeutic applications of various medicinal plants.

14) Medicine:
'Medicines' encompass substances used for treatment, prevention, or diagnosis of diseases. Herbal medicines, derived from plants, form an integral part of healthcare, particularly in traditional systems that leverage the metabolic activities of phytochemical constituents for therapeutic purposes.

15) Shri (Sr, Sri):
'Shree' is an honorific term often used in India, reflecting respect and reverence. It appears in institutional names, such as Shree Venkateshwara College of Paramedical Sciences, highlighting cultural significance in academic and professional environments.

16) Pharmacognostical:
'Pharmacognostical' pertains to pharmacognosy, the study of medicinal drugs derived from natural sources. It involves characterizing and standardizing plant materials to ensure quality, potency, and safety in herbal formulations, bridging traditional knowledge and modern scientific approaches.

17) Pharmacological:
'Pharmacological' relates to pharmacology, the branch of medicine concerned with the study of drug action. This discipline is vital for understanding the mechanisms of action, therapeutic effects, and potential side effects of natural compounds present in medicinal plants.

18) Container:
A 'container' is a vessel used to hold materials during extraction processes. Proper choice and handling of containers are essential in herbal preparations to prevent contamination and ensure the integrity of the extracts being produced.

19) Quality:
The phrase 'the quality' emphasizes the importance of standards and measures in evaluating herbal medicines. It underscores the need for comprehensive testing methods to ascertain the phytochemical content and therapeutic effects required for safe and effective usage.

20) Animal:
'Animals' in medicinal research often serve as test subjects for pharmacological studies, providing insights into the biological effects of plant-derived substances. This research helps to elucidate the safety and efficacy of herbal medicines for human use.

21) Pharmacology:
'Pharmacology' is the scientific study of drugs and their effects on biological systems. It encompasses understanding drug action mechanisms, therapeutic uses, side effects, and interactions, forming a critical component in validating traditional herbal remedies.

22) Dish (Dis):
'Dish' refers to laboratory equipment used for various purposes, such as mixing or observing reactions. In phytochemical studies, dishes could be utilized for carrying out tests that analyze the properties of extracted compounds.

23) Inflammation:
'Inflammation' is a biological response to harmful stimuli, often resulting in pain and swelling. Herbal studies explore anti-inflammatory properties of plant extracts, uncovering natural treatments that may alleviate symptoms related to various inflammatory conditions.

24) Observation:
'Observation' denotes the action of closely monitoring or examining experimental outcomes. In scientific research, careful observation is crucial for gathering accurate data and drawing valid conclusions regarding the efficacy of plant extracts in pharmacological studies.

25) Knowledge:
'Knowledge' encompasses the understanding derived from research and studies. In pharmacognosy, knowledge about the phytochemical constituents of plants is essential for developing effective herbal medicines, grounding therapeutic practices in both traditional and scientific evidence.

26) Substance:
'Substances' refer to individual chemical forms present in a compound. Identifying various substances within medicinal plants allows researchers to explore their health benefits and contribute to the overall efficacy of herbal treatments.

27) Tamilnadu (Tamil-nadu):
'Tamilnadu' is a state in southern India renowned for its rich cultural heritage, including traditional medicine practices utilizing local flora. The state's biodiversity offers numerous medicinal plants, encouraging studies to explore their pharmacological properties and health benefits.

28) Family:
'Family' refers to a systematic classification of related plant species, vital in phytochemistry. Understanding a plant's family aids researchers in predicting its potential medicinal properties based on known characteristics of previously studied relatives within that family.

29) Sharman (Sarma, Sarman, Sharma):
'Sharma' is a common surname in India, often associated with scholars and practitioners in various fields. The mention of Sharma in the context of pharmacognosy suggests contributions to research involving plant-based medicines and their potential health benefits.

30) Ulcer:
'Ulcer' represents a wound or sore on the body, particularly in areas like the stomach or intestines. Research into herbal medicine emphasizes finding effective treatments based on plant extracts known for their healing and anti-inflammatory properties.

31) Sugar:
'Sugar' refers to the class of carbohydrates, including glucose and fructose, which are vital for energy metabolism. In pharmacological studies, the regulation of blood sugar levels can be influenced by certain medicinal plants with hypoglycemic properties.

32) Edema (Oedema):
'Edema' is the medical term for swelling caused by excess fluid accumulation in tissues. Some herbal studies focus on extracting compounds with potential diuretic effects that may reduce edema, contributing to treatment options for related conditions.

33) Fainting (Fainted):
'Faint' can describe a state of weakness or dizziness. In relation to medicinal plants, compounds that alleviate symptoms of faintness, such as those with energizing or revitalizing properties, are of research interest in herbal studies.

34) Genu:
'Genu' usually indicates a knee-like structure or bend. While not the primary focus in herbal studies, anatomical terms like 'genu' may appear in discussions regarding plant morphology and adaptations that affect medicinal properties.

35) Hair:
'The hair' can refer to specific characteristics of a plant that influence its medicinal properties. In herbal studies, the presence of hairs may relate to the absorption of phytochemicals and the overall effectiveness of the extract.

36) Pain:
'Pain' is a physiological sensation indicating injury or disease. Herbal medicine explores various plant extracts for analgesic properties that can mitigate pain, forming a critical aspect of their therapeutic evaluation.

37) Rat:
'Rats' are often utilized in experimental studies for pharmacological testing due to their biological similarities to humans. They serve as models for understanding the effects of herbal extracts on health parameters, including pain and inflammation.

38) Arrangement:
'Arrangement' refers to the organization of plant parts, such as leaves, flowers, and roots. Understanding the arrangement of these components is critical for pharmacognostical studies, as it may influence the extraction process and yield of active compounds.

39) Discussion:
'Discussion' denotes the analytical interpretation of research findings. In herbal studies, the discussion section assesses the significance of the results, compares data with existing literature, and provides insights into the implications for traditional and modern medicine.

40) Developing:
'Developing' pertains to the process of advancing knowledge or skills. In the context of herbal medicine, developing research methodologies and understanding the pharmacological properties of plants contribute to the evolving field of natural product sciences.

41) Vaishnavi (Vaisnavi):
'Vaishnavi' is a common name in Indian culture and could refer to one of the researchers or contributors in studies related to herbal medicine. Such individuals often work on validating traditional practices through modern scientific methods.

42) Toxicity:
'Toxicity' refers to the degree to which a substance can harm living organisms. Understanding the toxicity of phytochemicals is crucial in herbal medicine to ensure the safe use of plant-derived products and prevent adverse health effects.

43) Sanskrit:
'Sanskrit' is an ancient language in India, where much of traditional medicinal knowledge is documented. Terms derived from Sanskrit are frequently utilized in herbal studies, highlighting the cultural significance and historical context of plant-based therapies.

44) Marathi:
'Marathi' is a language spoken in Maharashtra, India, representing one of the cultural dimensions where traditional medicines are explored. Its mention reflects the linguistic diversity in India and the connection between language and herbal practices.

45) Kannada:
'Kannada' is the language of Karnataka, India, where an array of traditional medicinal knowledge exists. The linguistic reference emphasizes the cultural heritage of herbal remedies and the importance of documentation for further research.

46) Tripuri:
'Tripuri' refers to a tribal community in India, which may have distinct traditional medicinal practices. Exploring the herbal knowledge from such communities can provide invaluable insights into alternative treatments and enhance research in ethnopharmacology.

47) Species:
'Species' represents a group of related organisms capable of interbreeding. In the field of pharmacognosy, identifying different plant species is essential for studying their unique phytochemical compositions and potential medicinal properties.

48) Mineral:
'Mineral' denotes naturally occurring inorganic substances vital in biological systems. In herbal medicine, minerals contribute to the therapeutic effects and may be present in plant extracts, influencing their overall health benefits.

49) Cancer:
'Cancer' is the uncontrolled growth of abnormal cells in the body. Research into phytochemicals from plants aims to discover anti-cancer properties, offering alternative therapeutic strategies to complement existing treatments.

50) Bitter:
'Bitter' describes a taste sensation often associated with the presence of certain phytochemicals. In herbal medicine, bitter compounds can stimulate digestive functions and may also contribute to the therapeutic effects of various herbal preparations.

51) Purity:
'Purity' refers to the absence of contaminants in herbal products. Ensuring the purity of plant extracts is critical for their safety and efficacy, emphasizing the need for stringent quality control measures in herbal production.

52) Tutti:
'Tutti' is the Kannada word for a specific plant, perhaps signifying local knowledge and the cultural importance of regional flora in traditional medicine. Recognizing local names enhances the relevance of ethnobotanical studies in understanding medicinal practices.

53) Hindi (Himdi):
'Hindi' is one of the primary languages in India, reflecting the linguistic diversity of the region. The mention of Hindi indicates the cultural context in which traditional medicine is practiced and the significance of language in herbal references.

54) Camel:
'Camel' refers to the domesticated animal often found in arid regions. Its mention in medicinal studies may relate to its dietary habits, which could provide insights into plant utilization in traditional medicine contexts.

55) Fever:
'Fever' is a common symptom indicating an underlying health issue, often treated with herbal remedies. Exploring plant extracts with antipyretic properties contributes to understanding their roles in alleviating fever symptoms.

56) Tamil:
'Tamil' is a Dravidian language spoken predominantly in Tamil Nadu, India. The reference emphasizes the rich cultural heritage of herbal medicine in the Tamil-speaking region, highlighting the integration of traditional knowledge in pharmacognostic studies.

57) Daha:
'Daha' could refer to a cultural or folkloric aspect associated with traditional medicine. Its mention reflects the need to understand the socio-cultural contexts within which herbal remedies are utilized and validated.

58) Pala:
'Pala' is a term that may signify local or herbal knowledge, particularly in relation to traditional practices in specific regions. Understanding regional terminology fosters a deeper appreciation of ethnobotanical diversity and its relevance in contemporary health practices.

59) King:
'King' could refer to the royal status or historical context in which traditional knowledge was preserved and passed down. This mention may highlight the importance of cultural heritage in the development of herbal medicine practices.

60) Hind:
'Hind' may refer to indigenous knowledge or practices specific to the Indian subcontinent. Recognizing the historical context emphasizes the significance of traditional healing systems in addressing health issues based on local flora.

61) Salt (Salty):
'Salt' is a naturally occurring mineral essential for human health, influencing bodily functions. In the context of medicinal plants, certain herbs may have salinity-related properties, impacting their therapeutic applications, particularly concerning electrolyte balance.

Other Science Concepts:

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Discover the significance of concepts within the article: ‘Standardization and solvent comparative study of abutilon hirtum l.’. Further sources in the context of Science might help you critically compare this page with similair documents:

Phytochemical, Traditional medicine, Taxonomy, Anti-inflammatory activity, World Health Organization, Phytochemical screening, Phytochemical analysis, Analgesic activity, Research article, Pharmacognosy, Ethanolic extract, Organoleptic character, Vernacular name, Organoleptic properties, Ethanol extract, Anti-diabetic activity, Antipyretic activity, Soxhlet extraction, Physiochemical Parameters, Pharmacognosy studies, Extraction procedure, Department of Pharmaceutics, Maceration technique, Phytoconstituent, College of Pharmacy, Natural drug, Soxhlet extraction process, Ethical research.

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