A clinical study of sandhigata vata (osteoarthritis) through nidana

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Journal name: World Journal of Pharmaceutical Research
Original article title: A clinical study of sandhigata vata (osteoarthritis) through nidana
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Author:

Dr. Avijit Das, Dr. Saurabh Kumar, Dr. Sandeep, Dr. Puja Nayak, Dr. Kuldeep Singh Chauhan, Dr. Anindita Debnath, Mr. Arunendra Kumar Singh


World Journal of Pharmaceutical Research:

(An ISO 9001:2015 Certified International Journal)

Full text available for: A clinical study of sandhigata vata (osteoarthritis) through nidana

Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research

Doi: 10.20959/wjpr202313-29086

Copyright (license): WJPR: All rights reserved


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Summary of article contents:

Introduction

Sandhigata vata, commonly known as osteoarthritis, is a significant vata vyadhi characterized by the involvement of vata dosha, particularly in elderly individuals or during the vruddha avastha (old age). This condition arises from the improper balance of doshas, leading to a decline in physical and mental well-being. Symptoms include joint pain, swelling, stiffness, and restricted movement. Due to its high prevalence and substantial impact on the quality of life, particularly in aged populations, this clinical study aims to explore its etiopathogenesis and the contributing factors, as well as to analyze the dietary habits and lifestyles of affected individuals.

The Role of Vata Dosha in Sandhigata Vata

Vata dosha is pivotal in maintaining physical functions and activities. In elderly individuals, a decline in dhatus (tissues) leads to an exacerbation of vata prakopa, which can result in various vataja disorders, including sandhigata vata. The interaction between the environment, dietary choices, and lifestyle habits greatly influences the onset and progression of this condition. The study emphasizes the need to understand these relationships to better manage and prevent the occurrence of sandhigata vata, which is particularly troubling for those in the vruddha avastha.

Impact of Diet and Lifestyle

The study highlights the role of ahara (diet) and vihara (lifestyle) in the management of sandhigata vata. Patients frequently reported a diet rich in non-vegetarian foods, and a substantial number exhibited habits that contribute to vata imbalance. Understanding the impact of diet and lifestyle choices is critical, as they significantly influence both the manifestation of symptoms and the disease's progression. By recording the food habits and daily regimens of patients, the study aims to provide insights into the potential etiological factors leading to sandhigata vata.

Historical and Cultural Context

The historical review of Indian medicine sheds light on the understanding of sandhigata vata throughout various periods, including references in ancient texts such as the Atharvaveda, Charaka Samhita, and Sushruta Samhita. This cultural context emphasizes the long-standing recognition of the condition, presenting a framework for its current study. The thorough documentation of symptoms, underlying causes, and treatment protocols in classical texts serves as a valuable resource for modern research, linking traditional Ayurvedic knowledge to contemporary clinical understanding.

Conclusion

In conclusion, the clinical study of sandhigata vata presents an opportunity to explore the interconnectedness of vata dosha, diet, lifestyle, and historical perspectives in understanding this prevalent condition. By examining these facets, the research aims to contribute to improving clinical practices and patient outcomes. Recognizing the higher incidence of sandhigata vata in the elderly, especially among women, underscores the importance of preventive measures and tailored interventions. Ultimately, this study seeks to bridge the gap between traditional Ayurvedic concepts and modern medical practices, fostering holistic care for those affected by osteoarthritis.

FAQ section (important questions/answers):

What is Sandhigata Vata and its significance in osteoarthritis?

Sandhigata Vata is an Ayurvedic term for osteoarthritis, characterized by pain, swelling, and stiffness in joints. It predominantly affects the elderly and is linked to vata dosha imbalances related to diet and lifestyle.

What were the aims of the clinical study on Sandhigata Vata?

The study aimed to investigate the etiopathogenesis of Sandhigata Vata, focusing on the relationship between dietary habits, lifestyle factors, and the incidence of the disease among patients attending the Amrapali Ayurvedic Medical College.

Who were the primary participants in this clinical study?

The study included at least 30 patients diagnosed with Sandhigata Vata, primarily from the age group of 50-60 years, attending the outpatient and inpatient departments of the medical college.

What dietary habits were observed among patients with Sandhigata Vata?

Most patients reported a mixed diet with a higher consumption of non-vegetarian food. This dietary pattern is potentially linked to the increased incidence of Sandhigata Vata symptoms.

What previous research has been done on Sandhigata Vata?

Many studies have been conducted across Ayurvedic institutes on Sandhigata Vata, exploring various treatment modalities and etiological factors, including the role of medications and therapies in its management.

What is the relationship between obesity and osteoarthritis in elderly individuals?

Obesity significantly increases the risk of osteoarthritis, particularly in weight-bearing joints like the knees. This condition is prevalent among elderly individuals, contributing to their overall disability and impaired quality of life.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “A clinical study of sandhigata vata (osteoarthritis) through nidana”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Vata:
Vata is one of the three doshas in Ayurveda, representing the elements of space and air. It governs movement, circulation, and the nervous system. Imbalances in Vata lead to disorders known as Vata vyadhi, impacting bodily functions significantly, particularly in the elderly who suffer from conditions like Sandhigata Vata (osteoarthritis).

2) Study (Studying):
The study entails the research process aimed at investigating specific phenomena, such as Sandhigata Vata. It analyzes etiology, symptoms, and treatment effectiveness, contributing valuable insights to enhance understanding and therapeutic approaches within Ayurveda.

3) Sandhi (Shandhi, Samdhi):
Sandhi, in Ayurveda, refers to the joints of the body. It is considered a marma (vital point) and plays a crucial role in mobility and function. The health of the Sandhi is directly linked to the overall balance of Vata, as disturbances in Vata can lead to joint disorders.

4) Sandhigata Vata (Sandhigata-vata):
Sandhigata-vata is a term used interchangeably with Sandhigata Vata in Ayurvedic texts, emphasizing the joint disorders caused by vata dosha imbalance. It encapsulates its symptoms, treatment modalities, and underlying causes, thereby forming a basis for clinical studies aiming at effective management of the condition.

5) Disease:
Diseases signify pathological conditions that disrupt normal bodily functions. In Ayurveda, the classification and understanding of diseases such as Sandhigata Vata allow practitioners to develop targeted treatment plans aimed at restoring balance and health.

6) Nidana:
Nidana refers to the cause or factors contributing to a disease in Ayurveda. Understanding the Nidana of Sandhigata Vata is crucial for developing prevention and treatment strategies. It includes lifestyle, dietary habits, and environmental factors that predispose individuals to this condition.

7) Sthana:
Sthana means a location or place, often used in Ayurvedic context to indicate the specific site of affliction in the body. In relation to Sandhigata Vata, Sthana helps in identifying which joints are affected, guiding appropriate treatment and therapeutic interventions.

8) Lakshana (Laksana):
Lakshana denotes the signs and symptoms of a disease. It serves as a guide for diagnosis in Ayurveda, distinguishing Sandhigata Vata through specific indicators like joint pain, swelling, and stiffness. Recognizing these can facilitate timely and effective management strategies for patients.

9) Samhita:
Samhita refers to ancient texts that compile knowledge on Ayurveda, including various medical theories and treatment philosophies. The reference to Samhita in relation to Sandhigata Vata underscores the importance of classical texts like Charaka and Sushruta in understanding and managing this condition.

10) Avastha:
Avastha indicates a state or stage, particularly in the context of age or health in Ayurveda. The term is significant in understanding that Sandhigata Vata primarily affects individuals in Vruddha (elderly) Avastha, where natural degenerative changes make them more susceptible to joint disorders.

11) Kala:
Kala translates to a time period or era in Ayurveda. It is essential for understanding the evolution of diseases like Sandhigata Vata over a person's lifespan, emphasizing that age-related factors and lifetime habits significantly contribute to the onset and severity of this condition.

12) Nidanasthana (Nidana-sthana):
Nidana-sthana is a specific section in Ayurvedic texts that focuses on the causes and origins of diseases. Understanding Nidana-sthana is crucial for developing effective treatments for Sandhigata Vata through identifying potential risk factors related to lifestyle and dietary habits.

13) Agnikarma (Agni-karma):
Agnikarma is a therapeutic technique in Ayurveda that involves the application of heat for treatment purposes. Its role in managing Sandhigata Vata illustrates an innovative approach to alleviating pain and inflammation in joints, showcasing Ayurveda's unique perspectives on chronic diseases.

14) Samgraha (Sangraha):
Sangraha signifies the collection or systematic compilation of knowledge in Ayurveda. This is pertinent for Sandhigata Vata as it provides practitioners with comprehensive information on the disease's history, treatment methods, and the importance of holistic approaches to management.

15) Shalya (Salya):
Shalya translates to surgical procedures in Ayurveda. It encompasses various techniques, including Agnikarma, for managing diseases like Sandhigata Vata. Understanding Shalya is essential for Ayurvedic practitioners to offer a full spectrum of treatment options, ranging from surgical to holistic care.

16) Dosha (Dosa):
Dosha refers to the three fundamental energies (Vata, Pitta, Kapha) in Ayurveda that govern physiological and psychological processes. The imbalance of Vata dosha is primarily responsible for Sandhigata Vata, indicating the importance of maintaining dosha equilibrium for disease prevention and management.

17) India:
India is the birthplace of Ayurveda, an ancient system of medicine that emphasizes holistic healing and the balance of bodily energies. The prevalence of Sandhigata Vata highlights the significance of Ayurvedic practices in addressing common health issues faced by the Indian population, particularly among the elderly.

18) Sign:
Sign refers to a manifestation or indicator of a condition, particularly in the context of medical diagnoses. Understanding the signs related to Sandhigata Vata is crucial for early detection and effective management of the disease, facilitating a comprehensive treatment approach.

19) Shalyatantra (Salyatantra, Shalya-tantra, Shalyatamtra):
Shalya-tantra is the branch of Ayurveda that deals with surgical procedures and the management of disorders requiring surgical intervention. Its relevance to Sandhigata Vata reflects the integration of surgical techniques in Ayurveda to treat conditions that can significantly disable patients.

20) Matra-basti:
Matra-basti is a therapeutic procedure involving the administration of medicated oil or liquid through the rectum, aimed at balancing doshas and alleviating disorders. Its application for managing Sandhigata Vata illustrates its therapeutic potential in treating joint and pain-related issues.

21) Vatavyadhi (Vata-vyadhi):
Vatavyadhi encompasses a variety of disorders attributed to Vata imbalance in Ayurveda. Its relevance in discussing Sandhigata Vata emphasizes the importance of recognizing and treating the underlying Vata disturbances contributing to osteoarthritis and joint health issues.

22) Madhyama:
Madhyama denotes the intermediate or moderate condition in Ayurveda. In relation to Sandhigata Vata, understanding Madhyama is important for evaluating the severity of the disease, as it often reflects stages between initial symptoms and advanced degenerative changes in joint health.

23) Ashtanga (Astanga, Ashtan-anga):
Ashtanga refers to the eight branches of Ayurveda, encompassing a comprehensive approach to health and disease management. Its principles guide the understanding of conditions like Sandhigata Vata, ensuring that treatment considers diverse factors from surgery to herbal remedies.

24) Medicine:
Medicine denotes disciplines focused on diagnosing, treating, and preventing diseases. In the context of Sandhigata Vata, Ayurvedic medicine integrates holistic approaches, recognizing the interconnectedness of physical, mental, and spiritual well-being in its treatment strategies.

25) Prakopa:
Prakopa means an exacerbation or acceleration of a condition, particularly related to dosha imbalances. In Sandhigata Vata, an understanding of Prakopa is essential, as it helps practitioners identify triggers for worsening symptoms and adjust treatment plans accordingly.

26) Tantra (Tantrism, Tamtra):
Tantra refers to a system or technique, particularly in the context of Ayurvedic practices. For Sandhigata Vata, Tantra involves various therapeutic approaches, including massages and herbal treatments, aimed at restoring balance to the bodily systems affected by diseases.

27) Vikara:
Vikara means a disorder or disease in Ayurveda. The term is significant when discussing Sandhigata Vata, as it illustrates how the imbalances within the body, particularly in Vata dosha, manifest as specific clinical symptoms impacting joint health.

28) Shotha (Sotha):
Shotha translates to swelling or edema in Ayurvedic terminology. In the context of Sandhigata Vata, Shotha is a critical symptom often observed in affected joints, indicating inflammation and the need for treatment that addresses both pain and swelling.

29) Vihara:
Vihara refers to lifestyle habits and routines in Ayurveda. It encompasses physical and psychological aspects of living that can influence health. In relation to Sandhigata Vata, identifying appropriate Vihara is crucial for preventing and managing the disease effectively.

30) Vyadhin (Vyadhi):
Vyadhi denotes a disease or disorder in Ayurveda. This term is essential for understanding conditions like Sandhigata Vata, facilitating a comprehensive approach to diagnosis and treatment through Ayurveda’s classification of various diseases and their etiological factors.

31) Matra:
Matra signifies measurement or dosage in Ayurveda. The exact Matra is vital when prescribing treatments, particularly in therapies for Sandhigata Vata, where the balance of herbs or medicated substances can determine the efficacy and safety of treatment outcomes.

32) Basti:
Basti refers to a therapeutic procedure in Ayurveda involving the administration of medicated liquids through the rectum. This treatment modality is particularly relevant for Sandhigata Vata, as it targets Vata imbalance and aims to relieve joint pain and improve mobility.

33) Kumar:
Kumar is a common surname in India, often associated with male individuals. In academic contexts, it may represent one of the authors or researchers involved in the clinical study related to Sandhigata Vata, contributing to the body of Ayurvedic literature.

34) Veda:
Vedic refers to anything relating to the Vedas, the ancient sacred texts of India. The relevance of Vedic literature lies in its foundational principles in Ayurveda, which informs practices and philosophies regarding health, lifestyle, and the understanding of conditions like Sandhigata Vata.

35) Food:
Food signifies the intake of substances that nourish the body, crucial for maintaining health. In the context of Sandhigata Vata, dietary choices can significantly affect the balance of doshas, highlighting the importance of proper nutrition to prevent and manage joint disorders.

36) Drug:
Drugs signify medicinal substances used for healing and treatment. In the context of Sandhigata Vata, understanding the types and formulations of Ayurvedic drugs plays a critical role in developing effective management strategies for joint health.

37) Mental health:
Mental health refers to psychological and emotional well-being. Its relevance in Sandhigata Vata underscores the interconnectedness of physical health and mental wellness, indicating that chronic pain associated with joint disorders can significantly affect a patient's overall mental state.

38) Reason:
Reason pertains to causes or motivations behind actions or conditions. Identifying the reason behind the onset of Sandhigata Vata, including dietary and lifestyle factors, is crucial for prevention and effective management of the disease.

39) Ashtangasamgraha (Astangasamgraha, Astangasangraha, Ashtanga-samgraha, Ashtanga-sangraha, Ashtangasangraha):
Ashtanga-sangraha is an important Ayurvedic text that compiles and summarizes the knowledge of Ayurveda across its eight branches. Its relevance to Sandhigata Vata lies in its comprehensive approach, offering guidance on diagnosis and management based on classical Ayurvedic principles.

40) Sushruta-samhita (Susruta-samhita):
Sushruta-samhita is a foundational Ayurvedic text authored by Sushruta, focusing on surgical techniques and management of diseases. Its insights are invaluable in understanding Sandhigata Vata, which aids practitioners in managing osteoarthritis and related joint issues effectively.

41) Ashtangahridaya (Astangahrdaya, Ashtanga-hridaya):
Ashtanga-hridaya is an essential Ayurvedic text that synthesizes knowledge across the eight branches of Ayurveda. It plays a critical role in understanding diseases like Sandhigata Vata, providing guidance on treatment protocols and holistic care approaches.

42) Madhavanidana (Madhava-nidana):
Madhava-nidana is an ancient text that particularly discusses diagnostic criteria and manifestations of diseases, including those associated with Vata. Its relevance to Sandhigata Vata is crucial for identifying symptoms and developing treatment plans based on Ayurvedic philosophy.

43) Yogaratnakara (Yoga-ratnakara):
Yogaratnakara is an Ayurvedic text that compiles diverse treatments and therapeutic strategies. Its insights are particularly valuable for managing conditions like Sandhigata Vata, providing practitioners with various approaches to restore health and balance in patients.

44) Inflammation:
Inflammation is a biological response to harmful stimuli, commonly associated with pain and swelling in joints. In the context of Sandhigata Vata, understanding inflammation is critical for developing effective treatments that target pain alleviation and restoration of joint function.

45) Atharvaveda (Atharva-Veda):
Atharvaveda is one of the four Vedas, containing hymns and knowledge relating to healing practices. Its references to health and Vata disorders lay foundational principles that guide Ayurvedic treatments, including those for conditions like Sandhigata Vata.

46) Rasashastra (Rasa-shastra, Rasasastra):
Rasashastra is the branch of Ayurveda focusing on alchemy and medicinal preparations. Its relevance in treating Sandhigata Vata is significant, as it offers insights into the use of potent herbal formulations and minerals for restoring health and balance.

47) Agriculture:
Agriculture refers to the practice of farming and cultivation of crops. Its connection to Sandhigata Vata lies in how agricultural lifestyles may influence physical strain and dietary habits, ultimately affecting joint health and the prevalence of osteoarthritis.

48) Kshirapaka (Ksirapaka, Kshira-paka):
Kshirapaka is an Ayurvedic process of preparing medicated milk. This preparation method is often discussed in managing joint conditions like Sandhigata Vata, as it provides nourishment that may alleviate symptoms of Vata imbalance.

49) Bhaishajya (Bhaisajya):
Bhaishajya translates to medicine or remedy in Ayurveda. It encompasses therapies and substances utilized in the treatment of diseases like Sandhigata Vata, emphasizing the importance of holistic approaches to restore patients' health.

50) Vatadosha (Vatadosa, Vata-dosha):
Vata-dosha embodies the qualities and influences associated with the Vata energy in the body. An imbalance in Vata-dosha is central to the development of Sandhigata Vata, where understanding its characteristics is vital for proper assessment and treatment approaches.

51) Prakarana:
Prakarana refers to sections or chapters in Ayurvedic texts that explain treatment methods. Its significance lies in providing methodologies for addressing specific diseases like Sandhigata Vata, guiding practitioners in their therapeutic approach.

52) Evolution:
Evolution denotes the progressive development of conditions or diseases over time. In the context of Sandhigata Vata, analyzing its evolution is essential for understanding risk factors, progression, and implications for effective preventive measures.

53) Attending:
Attending refers to patients visiting healthcare facilities. In the context of the study, it signifies the population engaged in the research on Sandhigata Vata, emphasizing real-world insights into the prevalence and impact of the condition.

54) Cakrapani (Cakra-pani):
Cakrapani is a revered commentator on Ayurvedic texts, contributing valuable interpretations and insights. His perspectives on conditions like Sandhigata Vata enhance the understanding and application of classical Ayurvedic knowledge in modern contexts.

55) Tridosha (Tridosa, Tri-dosha):
Tridosha represents the three doshas of Vata, Pitta, and Kapha in Ayurveda, essential for understanding balance in health and disease. The concept is particularly relevant to Sandhigata Vata, where Vata dosha imbalance leads to joint health issues.

56) Ayurveda (Ayus-veda):
Ayurveda is an ancient holistic system of medicine originating from India, emphasizing balance in body, mind, and spirit. Its relevance in treating conditions like Sandhigata Vata highlights the significance of holistic approaches in healthcare.

57) Nighantu (Nighamtu):
Nighantu denotes Ayurvedic lexicons or botanical catalogs. Understanding Nighantu is crucial in the context of Sandhigata Vata as it aids in the identification and classification of medicinal herbs effective in managing joint disorders.

58) Shallaki (Sallaki):
Shallaki, a resin obtained from Boswellia serrata, is widely used in Ayurveda for its anti-inflammatory properties. Its relevance in managing Sandhigata Vata highlights its therapeutic potential in alleviating joint pain and stiffness associated with osteoarthritis.

59) Rasayana (Rasa-ayana):
Rasayana signifies rejuvenation therapies in Ayurveda aimed at enhancing vitality and longevity. Its incorporation in treating Sandhigata Vata suggests that holistic rejuvenation can significantly contribute to managing age-related joint disorders.

60) Vatakara:
Vatakara refers to individuals who indulge in behaviors or diets that aggravate Vata dosha. In the context of Sandhigata Vata, understanding Vatakara habits provides insights into lifestyle changes necessary for preventing and managing the condition.

61) Guggulu:
Guggulu is a resin of the Commiphora mukul tree used in Ayurveda for its anti-inflammatory and analgesic properties. Its application in the management of Sandhigata Vata highlights the efficacy of natural substances in alleviating symptoms associated with joint disorders.

62) Hridaya (Hrdaya):
Hridaya translates to the heart in Sanskrit, often used metaphorically to represent core principles in Ayurveda. Understanding Hridaya is essential for grasping the holistic nature of health, especially when addressing conditions such as Sandhigata Vata.

63) Madhava:
Madhava is often associated with Madhava Nidana, referring to its historical context in Ayurvedic literature. References to Madhava contribute significantly to the understanding and historical perspectives on diseases like Sandhigata Vata within Ayurvedic study.

64) Kalpana:
Kalpana often denotes creativity or conceptualization, especially in preparing herbal formulations. Its relevance lies in the innovative strategies employed in managing Sandhigata Vata through customized Ayurveda treatments tailored to individual patient needs.

65) Chauhan:
Chauhan is a common surname in India, typically associated with individuals from specific cultural backgrounds. In academic texts, it might refer to a researcher or practitioner involved in Ayurvedic studies on Sandhigata Vata, contributing to the knowledge base.

66) Kandara (Kamdara):
Kandara refers to tendons in Ayurveda. Understanding the role of Kandara is essential when discussing joint health in Sandhigata Vata, as tendons are critical structures affected in the pathology of joint disorders.

67) Kunduru (Kumduru):
Kunduru refers to the plant used in Ayurvedic medicine, known for its ability to treat joint ailments. Its relevance in the context of Sandhigata Vata highlights the use of specific herbal remedies in managing osteoarthritis symptoms.

68) Shuddha (Suddha):
Suddha denotes purity in Ayurvedic terminology, emphasizing the importance of unadulterated substances in treatments. This principle is vital for managing Sandhigata Vata, ensuring that therapeutic interventions maintain high standards of quality.

69) Samana (Shamana):
Shamana refers to the pacification of doshas or symptoms in Ayurveda. In the context of Sandhigata Vata, Shamana therapies focus on alleviating joint pain and inflammation, essential for improving patient quality of life.

70) Pramana (Pramanas):
Pramana signifies measurement or evidence in Ayurvedic context. Its application in studying Sandhigata Vata involves assessing treatment efficacy and outcomes, guiding practitioners in their therapeutic decision-making process.

71) Mahant:
Mahant often refers to a revered or significant person in religious or scholarly contexts. In the context of Ayurvedic studies on Sandhigata Vata, this designation may denote key figures who have contributed significantly to the exploration of this condition.

72) Sadhya:
Sadhya refers to the possibility of curing or overcoming a disease in Ayurveda. Understanding the Sadhya aspect of Sandhigata Vata is essential for setting realistic expectations for patients regarding treatment outcomes and disease management.

73) Kshaya (Ksaya):
Kshaya means depletion or reduction, often relating to Dhatus in Ayurveda. In discussing Sandhigata Vata, Kshaya highlights the age-related degenerative changes affecting joints and the need for strategies aimed at restoring balance and health.

74) Vataja (Vata-ja):
Vataja denotes conditions or diseases arising from the imbalance of Vata dosha. In the context of Sandhigata Vata, recognizing Vataja characteristics is crucial for devising effective treatment protocols to address the unique manifestations of this joint disorder.

75) Sharman (Sarma, Sarman, Sharma):
Sharma, often a common surname in India, can also signify relevance in academic literature. In Ayurvedic studies, Sharma may refer to a contributor or researcher focused on conditions like Sandhigata Vata, expanding the body of knowledge.

[Note: The above list is limited to 75. Total glossary definitions available: 103]

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