Ethnopharmacological review on puliyathi chooranam - siddha herbal formulation

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Journal name: World Journal of Pharmaceutical Research
Original article title: Ethnopharmacological review on puliyathi chooranam - siddha herbal formulation
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Author:

G. Tamilarasan, A. Areesh Kumar, S. Sushma, V. Divya Bharathi and Dr. M. D. Saravana Devi, M. D. (S)


World Journal of Pharmaceutical Research:

(An ISO 9001:2015 Certified International Journal)

Full text available for: Ethnopharmacological review on puliyathi chooranam - siddha herbal formulation

Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research

Doi: 10.20959/wjpr202314-29325

Copyright (license): WJPR: All rights reserved


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Summary of article contents:

Introduction

The Siddha system of medicine is a traditional healing practice predominantly found in South India, known for its holistic approach toward health and disease management. This system identifies and classifies a vast range of ailments, focusing on the balance of three humors: Vali, Azhal, and Aiyam. Among the numerous diseases addressed, diabetes, specifically Type 2 Diabetes Mellitus (T2DM), has emerged as a significant global health concern. With the World Health Organization (WHO) reporting that noncommunicable diseases, including diabetes, account for a substantial portion of global fatalities, there is a pressing need to explore effective herbal treatments. This mini-review centers on "Puliyathi Chooranam," a traditional Siddha herbal formulation, emphasizing its anti-diabetic properties.

Anti-Diabetic Properties of Puliyathi Chooranam

Puliyathi Chooranam is recognized for its potent anti-diabetic activity derived from ancient Siddha literature. This herbal formulation includes key ingredients such as Tamarindus indica and Tinospora cordifolia, which have established therapeutic benefits. Tamarind, commonly known for its sour fruit, possesses properties that include laxative, carminative, and astringent effects, while its seeds and bark have applications in treating various ailments. Furthermore, tinospora is noted for its capabilities in managing fever and diabetes, showcasing its extensive medicinal utility. The combination of these ingredients contributes to Puliyathi Chooranam's effectiveness in lowering elevated blood glucose levels in T2DM patients.

Pharmacological Activites of Tamarindus indica

Tamarindus indica is celebrated for its diverse pharmacological activities, primarily attributed to its rich phytochemical composition. This plant contains various chemical constituents, including flavonoids, tannins, and other antioxidant compounds, which work synergistically to provide health benefits. The seeds, fruit, and leaves demonstrate properties such as antioxidant effects, immunomodulatory actions, and hypolipidemic activities, making tamarind a valuable addition to dietary regimens. Research has indicated its potential in alleviating oxidative stress and promoting liver health, further establishing its significance in traditional medicine. These activities highlight the importance of Tamarindus indica in managing diabetes and associated complications.

Therapeutic Benefits of Tinospora cordifolia

Tinospora cordifolia, another key component of Puliyathi Chooranam, has gained recognition for its wide-ranging therapeutic effects. This herb is traditionally employed in Siddha medicine to treat an array of conditions, including diabetes, jaundice, and respiratory disorders. Its chemical profile consists of various bioactive compounds, such as alkaloids, glycosides, and polysaccharides, which contribute to its anti-diabetic, anti-inflammatory, and antimicrobial properties. Research supports its efficacy in enhancing insulin sensitivity and reducing blood glucose levels, emphasizing the herb's role as a complementary treatment in managing diabetes. The broad medicinal applications of Tinospora cordifolia highlight its therapeutic potential in various health conditions.

Conclusion

Puliyathi Chooranam represents a valuable traditional Siddha herbal formulation with significant anti-diabetic activity, primarily due to its integral components, Tamarindus indica and Tinospora cordifolia. The pharmacological properties of these herbs not only support their use in diabetes management but also emphasize their broader therapeutic applications in traditional medicine. Given the rising global burden of diabetes, further research and clinical trials are warranted to substantiate the efficacy of Puliyathi Chooranam and explore its potential role in contemporary evidence-based healthcare practices. The exploration of such traditional formulations could pave the way for new, effective treatment strategies for managing chronic conditions akin to diabetes.

FAQ section (important questions/answers):

What is the main focus of this ethnopharmacological review?

The review focuses on 'Puliyathi Chooranam,' a Siddha herbal formulation used to lower elevated blood glucose levels in Type 2 Diabetes Mellitus (T2DM).

Which plants are primary ingredients in Puliyathi Chooranam?

Puliyathi Chooranam primarily contains Tamarindus indica (Tamarind) and Tinospora cordifolia (Seendhil), known for their medicinal properties, particularly in treating diabetes.

What is the therapeutic use of Tamarind in traditional medicine?

Tamarind is traditionally used to prevent scurvy, treat ulcers, improve digestion, and act as a laxative due to its rich nutrient profile.

What potential benefits does Tinospora cordifolia offer?

Tinospora cordifolia exhibits anti-diabetic, anti-inflammatory, and immunomodulatory effects, making it valuable in treating various ailments, including diabetes.

What are the key pharmacological actions of Tamarind seed?

Tamarind seeds possess antioxidant effects and are beneficial in cholesterol management, potentially aiding in liver protection and smooth muscle relaxation.

Why is there a need for further investigation on these herbal formulations?

Further investigation is needed to validate the therapeutic efficacy of these plants with modern techniques for potential use in evidence-based medicine.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Ethnopharmacological review on puliyathi chooranam - siddha herbal formulation”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Activity:
Activity refers to the various biological effects that a drug or herbal formulation can have, particularly concerning its pharmacological properties. In the context of this review, the anti-diabetic activity of Puliyathi Chooranam highlights the importance of natural substances in managing elevated blood glucose levels and associated health issues.

2) Disease:
Diseases encompass a broader range of ailments beyond individual health issues. This term refers to the plethora of conditions identified within the Siddha system of medicine, which lists and categorizes prevalent health problems, including over 4448 recognized ailments such as metabolic disorders and infectious diseases traditionally treated with herbs.

3) Siddha:
Siddha is an ancient system of medicine unique to South India, renowned for its holistic approach and extensive pharmacopoeia. The review focuses on Siddha medical formulations like Puliyathi Chooranam, aiming to promote the significance of this traditional practice in modern medicine and health management.

4) Tamarind:
Tamarind refers to the fruit of the Tamarind tree, recognized for its culinary and medicinal uses. In this review, Tamarind is featured as a principal ingredient in Puliyathi Chooranam, known for its anti-diabetic properties and various health benefits, particularly in traditional Indian medicine.

5) Tamarindus indica:
Tamarindus indica, the scientific name for the tamarind tree, describes its botanical classification. This species is significant in Siddha and Ayurvedic medicine due to its various health benefits, including the regulation of blood sugar, anti-inflammatory properties, and use as a laxative, pivotal for formulations like Puliyathi Chooranam.

6) Medicine:
Medicine is the science and practice of diagnosing, treating, and preventing diseases. In this context, the review emphasizes Siddha medicine, showcasing its unique herbal formulations and traditional practices as effective therapeutic options, particularly concerning chronic conditions like diabetes.

7) Tinospora cordifolia:
Tinospora cordifolia is a crucial medicinal plant in traditional medicinal systems, esteemed for its various therapeutic properties. The review highlights its role in forms such as Puliyathi Chooranam due to its anti-diabetic, anti-inflammatory, and immunomodulatory effects, underscoring the importance of this species.

8) Cancer:
Cancer refers to a group of diseases characterized by uncontrolled cell growth and potential metastasis. The review indicates the traditional medicinal use of various herbs, including those in Puliyathi Chooranam, which may provide therapeutic benefits against cancer, aligning traditional practices with modern oncological approaches.

9) India:
India serves as the geographical and cultural backdrop for this review, representing a rich heritage of traditional medicine practices. The indigenous knowledge systems within India, particularly Siddha medicine, are fundamental to the application of herbal formulations in treating common diseases faced by the population.

10) Species:
Species in this context indicates the biological classification of different plants discussed in the review. Proper identification of species such as Tamarindus indica and Tinospora cordifolia is essential for understanding their medicinal properties and the rationale behind their use in Siddha formulations.

11) Family:
Family refers to the taxonomic rank in botanical classification. The review categorizes plants like Tamarindus indica under specific families, essential for recognizing the shared characteristics and potential health benefits of plants within the same family commonly used in traditional medicine.

12) Animal:
Animals refer to the broader category of living organisms used in studies or research. The review mentions various animal studies to demonstrate the efficacy of traditional herbal medicine in treating conditions like diabetes, supporting the clinical relevance of Siddha medicine.

13) Blood:
Blood refers to the bodily fluid that circulates via the vascular system, carrying nutrients, hormones, and waste products. The review emphasizes the importance of blood glucose levels in diabetes management and how herbal formulations like Puliyathi Chooranam aim to regulate these levels effectively.

14) Rat:
Rats are commonly used as model organisms in scientific research, particularly in pharmacological studies. The review refers to various studies conducted on diabetic rat models to evaluate the effectiveness of Siddha herbal formulations, showcasing their relevance in experimental validation of traditional medicine.

15) Sugar:
Sugar, particularly glucose, plays a central role in energy metabolism and is crucial in diabetes management. The review discusses how certain herbal formulations, such as Puliyathi Chooranam, target elevated blood sugar levels, underscoring the importance of sugar regulation in treating diabetes.

16) Fever:
Fever is a common symptom that indicates underlying health conditions. The review highlights the role of traditional herbal formulations in treating fever and related ailments, showcasing the holistic nature of Siddha medicine in managing a range of symptoms and promoting overall health.

17) Death:
Death relates to the ultimate outcome of uncontrolled diseases, including those preventable by effective treatments. The review highlights the significant mortality rates due to diabetes and emphasizes the importance of herbal formulations to manage this condition and decrease the risk of associated deaths.

18) Tamil:
Tamil refers to the language and cultural identity predominant in Tamil Nadu, South India. Traditional practices of Siddha medicine are deeply interwoven with Tamil culture, and the formulation and application of herbal treatments often stem from this rich cultural heritage.

19) Tamilnadu (Tamil-nadu):
Tamil Nadu is a state in southern India known for its rich cultural heritage and traditional medicinal practices, including Siddha medicine. The review's emphasis on herbal formulations from Tamil Nadu highlights the region’s significance in preserving traditional medicine and its contributions to health care.

20) Flavonoid:
Flavonoids are a class of phytonutrients found in many fruits and vegetables, known for their antioxidant properties. The review mentions flavonoids in the context of herbal formulations, indicating their role in providing health benefits such as reducing inflammation and controlling blood sugar levels.

21) Toxicity:
Toxicity refers to the degree to which a substance can harm organisms. This review often explores the safety profiles of herbal formulations, assessing toxicity levels to ensure the medicinal use of plants, such as those in Puliyathi Chooranam, is effective without adverse effects.

22) Chennai:
Chennai is the capital city of Tamil Nadu and a hub for Siddha medicine. The review references Chennai as the location for Government Siddha Medical College, where traditional medicine research and education occur, emphasizing its importance in promoting and preserving Siddha practices.

23) Water:
Water is a crucial solvent in medicinal preparations and home remedies. The review discusses the importance of aqueous extracts of herbal formulations, showcasing how water plays a role in dissolving active compounds to facilitate their therapeutic effects in managing diseases.

24) Ulcer:
Ulcer refers to a localized injury or sore found within the skin or mucous membrane. The review discusses the potential of herbal formulations to treat ulcers, highlighting the significance of traditional medicine in addressing various gastrointestinal and dermatological issues.

25) Nadu:
Nadu translates to

[Note: The above list is limited to 75. Total glossary definitions available: 97]

Other Science Concepts:

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Discover the significance of concepts within the article: ‘Ethnopharmacological review on puliyathi chooranam - siddha herbal formulation’. Further sources in the context of Science might help you critically compare this page with similair documents:

Tinospora cordifolia, Tamarindus indica, Clinical examination, Dysentery treatment, Herbal preparation, Traditional medicine, Evidence-based medicine, Therapeutic use, Diabetes, Medicinal use, World Health Organisation, Clinical trial, Therapeutic efficacy, Anti-inflammatory activity, Antioxidant activity, Pharmacological activities, Experimental model, Hypolipidemic effect, Anticancer activity, Herbal Medication, Antifungal activity, Nutritional support, Antioxidant Effect, Anti-diabetic activity, Postprandial glucose, Hypoglycemic action, Systemic circulation, Noncommunicable disease, Siddha system of medicine, Gut health, Renal cell carcinoma, Environmental toxin, Eight-fold Examination, Siddha Sasthric Medicines, Ethnopharmacological review.

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