Review of Manimandhirathi Chooranam for acid peptic disorders.
Journal name: World Journal of Pharmaceutical Research
Original article title: A phyto-pharmacological review on siddha herbomineral formulation manimandhirathi chooranam for gunmam (acid peptic disorders)
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A. Girija, S. Sushma, M. Jagadeeshbabu, S. Matheshvaran and M. D. Saravana Devi
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: A phyto-pharmacological review on siddha herbomineral formulation manimandhirathi chooranam for gunmam (acid peptic disorders)
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr202314-29317
Copyright (license): WJPR: All rights reserved
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Summary of article contents:
1) Introduction
Siddha medicine is a traditional healing system widely practiced in southern India, emphasizing the balance of the three vital humors: Vadham, Pitham, and Kabam. One of the health issues addressed in this system is Gunmam, which corresponds to what modern medicine recognizes as Acid Peptic Disorders, including peptic ulcer disease. With an annual global impact on around 4 million individuals and a prevalence rate of 5-10%, managing peptic ulcer disease has gained importance. The Siddha literature presents a variety of treatments that incorporate herbal, mineral, and animal products, among which the herbomineral formulation called Manimandhirathi chooranam is noted for its efficacy in treating Gunmam.
2) The Role of Manimandhirathi Chooranam
Manimandhirathi chooranam, referenced in the ancient text “Agasthiyar Mani 4000 ennum vaithiya sinthamani venba Muthal pagam,” comprises seven key ingredients, each selected for their medicinal properties. These components include Sodium Chloride, Cuminum cyminum, Carum copticum, Zingiber officinale, Piper longum, Piper nigrum, and Terminalia chebula. The formulation is noted for its ease of preparation and consumption, making it accessible for patients. The ingredients have demonstrated phytochemical profiles and pharmacological properties that contribute to their effectiveness against ailments associated with Gunmam.
3) Pharmacological Properties of the Ingredients
Each ingredient in Manimandhirathi chooranam possesses distinct pharmacological properties that collectively support digestive health. For instance, Cuminum cyminum (cumin) shows antiulcer and antioxidant activities while Zingiber officinale (ginger) is known for its carminative and digestive-stimulating properties. Additionally, Piper longum (long pepper) and Piper nigrum (black pepper) both exhibit anti-inflammatory and antimicrobial effects, enhancing the formulation's overall therapeutic potential. Terminalia chebula, known for its variety of bioactive compounds, has promising antiulcerogenic properties, further underscoring the collective efficacy of the ingredients against Acid Peptic Disorders.
4) Preparation and Administration of Manimandhirathi Chooranam
The preparation of Manimandhirathi chooranam involves grinding specified quantities of its ingredients into a fine powder and storing them in a clean, airtight container. The chosen route of administration is oral, with a typical dosage of 1 to 2 grams twice daily, taken with warm water as an adjuvant. This preparation method not only ensures the preservation of the active compounds but also facilitates easy consumption for patients suffering from Gunmam. Such accessibility reinforces the use of Siddha formulations in everyday healthcare settings.
5) Conclusion
The review highlights the significance of Manimandhirathi chooranam as a cost-effective and easily preparable treatment option for Gunmam, aligning with the principles of Siddha medicine. All ingredients demonstrate well-documented anti-ulcer, anti-inflammatory, and gastroprotective effects, establishing the formulation's safety and efficacy. As a result, Manimandhirathi chooranam stands out among various treatments available for Acid Peptic Disorders, offering a traditional yet scientifically backed approach to managing this widespread health issue.
FAQ section (important questions/answers):
What is the primary condition treated by Manimandhirathi chooranam?
Manimandhirathi chooranam is primarily indicated for Gunmam, which is akin to acid peptic disorders like peptic ulcers.
Which ingredients are included in Manimandhirathi chooranam formulation?
The formulation includes seven ingredients: Indhuppu, Seeragam, Asamadha omam, Sukku, Thippili, Milagu, and Kadukkai, each with specific health benefits.
What are the main pharmacological properties of Manimandhirathi chooranam?
The formulation exhibits anti-ulcer, anti-inflammatory, antioxidant, and gastroprotective properties, enhancing its efficacy for treating Gunmam.
How should Manimandhirathi chooranam be administered?
Manimandhirathi chooranam is taken orally, at a dosage of 1 to 2 grams, twice daily, preferably with warm water.
What are common causes of acid peptic disorders?
Common causes include stress, high spice consumption, smoking, alcohol intake, Helicobacter pylori infection, and long-term NSAIDs use.
Is Manimandhirathi chooranam safe and effective?
Yes, all ingredients in Manimandhirathi chooranam are safe, cost-effective, and easily prepared, showing significant therapeutic potential for Gunmam treatment.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Review of Manimandhirathi Chooranam for acid peptic disorders.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Siddha:
Siddha is an ancient Indian system of medicine that emphasizes a holistic approach to health and wellness. Originating from southern India, it integrates spirituality and natural remedies, focusing on the balance of three vital humors: Vadham, Pitham, and Kabam. Siddha medicine utilizes herbal, mineral, and animal products to treat various ailments.
2) Girija (Giri-ja):
Girija refers to the primary author of the reviewed study on the Siddha herbomineral formulation. As a postgraduate scholar in Siddha Pharmacology, Girija contributes significantly to the research on traditional medicine, particularly its phytochemical properties and potential benefits for chronic health issues such as peptic disorders.
3) Pharmacological:
Pharmacological pertains to the field of pharmacology, which studies the effects of drugs and their mechanisms of action in the body. It is essential in understanding how different substances, including natural herbal compounds, affect physiological functions and contribute to treating diseases, particularly those outlined in traditional systems like Siddha medicine.
4) India:
India is a diverse nation located in South Asia, known for its rich heritage and multiple systems of traditional medicine, including Siddha, Ayurveda, and Unani. This cultural backdrop supports holistic healing approaches that incorporate spirituality, lifestyle, and herbs unique to regional flora, impacting health care practices significantly.
5) Medicine:
The medicine signifies the practice and application of remedies used for treating illnesses. Within Siddha systems, the concept incorporates holistic approaches that consider individual body types and the balance of humors, utilizing natural substances to achieve health.
6) Drug:
Drugs are substances used to diagnose, treat, or prevent illness. In Siddha, the classification and preparation of drugs focus on natural ingredients rooted in tradition, emphasizing the effectiveness of herbal and mineral combinations in achieving optimal health.
7) Species:
Species denotes a group of organisms capable of interbreeding and producing fertile offspring. In the context of the reviewed formulation, it identifies the distinct plants used in making Siddha medicines, each possessing unique phytochemical properties contributing to their therapeutic effects on health disorders.
8) Family:
Family refers to a taxonomic rank in biological classification, grouping related species that share common characteristics. In pharmacology, understanding the family of a medicinal plant helps in recognizing its healing properties and potential use in treating specific health conditions, thereby enhancing the efficacy of traditional medicine.
9) Genu:
Genu refers to a term often used in biological taxonomy, though repeated often as a typo for 'genus.' Understanding genus classification enhances the ability to identify plant families that contribute to traditional medicines, allowing for more precise applications in pharmacological contexts.
10) Zingiber officinale:
Zingiber officinale, commonly known as ginger, is a plant utilized extensively in traditional and modern medicine for its antioxidant and anti-inflammatory properties. Its roots are known for easing digestive issues and have been studied for their potential in treating a variety of gastrointestinal disorders.
11) Terminalia chebula:
Terminalia chebula, known as haritaki, is used in Siddha and Ayurvedic medicine for its potent antiulcer, antimicrobial, and antioxidant properties. Its fruit is valued for enhancing digestive health and overall wellness, making it a significant ingredient in various herbal formulations.
12) Cuminum cyminum:
Cuminum cyminum, or cumin, is a spice known for its medicinal properties, including antimicrobial and anti-inflammatory effects. It is utilized in Siddha formulations for its potential to help with digestive disorders, reinforcing the connection between culinary ingredients and their health benefits.
13) Piper longum:
Piper longum, commonly known as long pepper, has historical significance in traditional medicine. Its pharmacological properties include antiulcer and antioxidant effects, making it a valuable component of Siddha formulations aimed at treating gastrointestinal issues and enhancing overall health.
14) Tamilnadu (Tamil-nadu):
Tamilnadu is a southern Indian state known for its rich cultural heritage and ancient medical practices, including Siddha medicine. It emphasizes holistic healing and the use of local herbal resources, contributing to the preservation and promotion of traditional health care systems.
15) Disease:
Diseases refer to various health conditions affecting bodily functions. Siddha medicine aims to treat diseases holistically, using natural herbs and minerals tailored to individual body types, emphasizing prevention and overall well-being rather than just symptom alleviation.
16) Ulcer:
Ulcers are sores that occur in the lining of organs such as the stomach or intestines. In Siddha medicine, addressing ulcers involves identifying the underlying imbalances and employing herbal remedies designed to promote healing and restore digestive health.
17) Tamil:
Tamil is a Dravidian language spoken predominantly in Tamil Nadu and recognized for its rich literary tradition and cultural significance. Its role extends beyond communication to preserve and disseminate knowledge of traditional practices, including Siddha medicine and herbal formulations.
18) Nadu:
Nadu refers to 'land' or 'country' in Tamil, often used in geographic terms within India. In the context of Siddha medicine, it signifies the regional practices and locally available resources that influence the formulation and application of traditional remedies.
19) Salt (Salty):
Salt is a natural mineral primarily composed of sodium chloride, widely used in food and medicine. In Siddha formulations, specific types of salt, like rock salt, are employed for their health benefits, including aiding digestion and balancing bodily functions.
20) Rock salt:
Rock salt, or sodium chloride impura, is an unrefined form of salt used in Siddha medicine for its digestive and therapeutic properties. Its mineral content is believed to enhance overall health, making it a vital component in various traditional formulations.
21) Phytochemical:
A phytochemical refers to a specific compound derived from plants with biological activity. These compounds play a critical role in traditional medicine, including Siddha, where they contribute to the therapeutic effects of herbal formulations on diseases and overall health.
22) Pharmacology:
Pharmacology is the study of drugs and their interactions with biological systems. It encompasses the understanding of how herbal remedies from systems like Siddha can alleviate symptoms, promote healing, and serve as alternatives to conventional pharmaceuticals.
23) Chennai:
Chennai is the capital city of Tamil Nadu and a cultural hub in India. Home to various traditional medical practices, including Siddha, the city serves as a center for research and the promotion of indigenous healing methods that utilize local flora and pharmacological principles.
24) Habitat:
Habitat refers to the natural environment where a species of plant or animal lives. Understanding the habitat is crucial for identifying medicinal plants used in Siddha formulations, as different climates and soils contribute to their availability and medicinal properties.
25) Mineral:
Minerals are inorganic substances essential for various physiological functions in the body. In Siddha medicine, they are often incorporated into formulations for their therapeutic properties, supporting health and vitality through natural combinations of herbal and mineral resources.
26) Post:
Post refers to an academic or professional position often pursued after obtaining a degree. In the context of this review, authors are likely engaged in advanced studies and contribute to the ongoing research and application of Siddha medicinal practices.
27) Antibiotic (Antibacterial):
Antibacterial indicates the property of substances that combat bacterial infections. Many medicinal plants in Siddha formulations exhibit antibacterial effects, making them valuable in treating inflammatory and infectious diseases through natural remedies derived from indigenous flora.
28) Science (Scientific):
Science refers to the systematic study of the natural world through observation and experimentation. The integration of scientific principles into Siddha medicine validates traditional practices, providing a modern understanding of herbal efficacy and promoting evidence-based approaches to health care.
29) Agasthiyar:
Agasthiyar is an ancient Tamil sage credited with significant contributions to Siddha medicine. He is revered not only as a philosopher and saint but also as an authoritative figure whose writings form the basis for many traditional medicinal practices, including herbal remedies.
30) Cintamani (Cinta-mani, Cimtamani):
Sinthamani refers to a classic text in Siddha medicine written by sages, including Agasthiyar. This text explores various herbal formulations, healing methods, and principles that continue to guide practitioners in the use of traditional remedies for a wide range of ailments.
31) Powder:
Powder refers to the physical form of many medicinal ingredients in Siddha medicine, which are often ground into fine powders for ease of use and better absorption. This formulation method enhances the efficacy of the herbal ingredients in treating various health conditions.
32) Mani:
Mani is a Tamil word that signifies 'gem' or 'jewel,' often used in the context of traditional texts and formulations that highlight the value of knowledge and medicinal practices in enriching health, embodying both physical and spiritual healing principles.
33) Northern India:
Northern India is a region known for its diverse geography and cultures, contributing to the rich tapestry of traditional medicine. The introduction of various herbs and minerals in Siddha formulations reflects the unique environmental and cultural influences of this area.
34) Forest:
Forest indicates natural wooded areas that house a diversity of flora used in traditional medicine. Its role in sourcing plants for Siddha medicine is critical and exemplifies the strong association between natural environments and health solutions.
35) Inflammation:
Inflammation is a biological response of body tissues to harm, causing symptoms like redness and pain. Siddha medicine identifies inflammation as a health issue and addresses it using herbal remedies known for their anti-inflammatory properties, aiding in the recovery of various ailments.
36) Afghanistan:
Afghanistan is a country known for its historical trade routes and diverse flora. The herbal knowledge from this region may have influenced Siddha practices, introducing various plants as essential components in traditional medicine, illustrating the interconnectedness of global herbal medicine.
37) Container:
Container refers to a vessel used for storing medicinal preparations. In Siddha, the storage conditions can affect the potency and safety of herbal compounds, making the choice of container crucial for preserving the efficacy of traditional medicines.
38) Himalaya (Hima-alaya):
Himalaya, similar to the Himalayas, denotes the vast mountain range. It is significant for traditional and modern medicine, offering various plants with beneficial properties used in Siddha formulations, enhancing the therapeutic options available for managing health conditions.
39) Vomiting:
Vomiting is the forceful expulsion of stomach contents, often a symptom of gastrointestinal disturbances. Siddha medicine explores various causes of vomiting and utilizes herbal remedies to alleviate discomfort and restore digestive balance through therapeutic formulations.
40) Burning (Burn, Burned, Burnt):
Burning describes a sensation often linked to digestive disturbances or irritation in bodily tissues. Siddha medicine identifies burning sensations as symptoms of imbalances, and remedies are formulated to soothe and restore equilibrium, enhancing overall gastrointestinal health.
41) Bengal (Bemgal):
Bengal is a region known for its rich cultural and agricultural heritage. The diverse flora of Bengal contributes to traditional medicinal practices, including Siddha, where local plants are integral to formulating effective remedies for various health conditions.
42) Mysore:
Mysore is a city located in Karnataka, India, noted for its lush landscapes and historical ties to traditional medicine. Its proximity to rich biodiversity makes it a significant source for plants used in Siddha formulations, bridging regional knowledge with herbal medicine.
43) Punjab:
Punjab is a region in northern India recognized for its agricultural richness and traditional practices. The herbal plants from Punjab contribute valuable resources for Siddha medicine, enhancing the diversity of ingredients leveraged for holistic healing.
44) Milagu:
Milagu refers to black pepper, a spice famed for its culinary and medicinal uses. In Siddha medicine, milagu is praised for its potential gastrointestinal benefits, including anti-inflammatory and digestive properties, contributing to the effectiveness of various herbal formulations.
45) Cancer:
Cancer is a complex group of diseases characterized by uncontrolled cell growth. Siddha medicine aims to address cancer through natural remedies that may include anti-cancer properties, showcasing the potential of herbal formulations in enhancing overall treatment strategies.
46) Nausea:
Nausea is an unsettling sensation often leading to vomiting. Siddha medicine recognizes this symptom as a digestive imbalance and incorporates specific herbal remedies designed to alleviate nausea and restore comfort, underscoring the connection between gut health and overall well-being.
47) Animal:
Animal refers to living organisms that belong to the animal kingdom. In Siddha medicine, various animal products are sometimes included as ingredients in herbal formulations, reflecting the traditional practices that incorporate both flora and fauna for holistic healing.
48) Cotton:
Cotton is a fiber derived from the cotton plant, often used in fabric production. Within the context of Siddha, cotton may serve practical purposes, such as making cloth for sieving powdered medicines, emphasizing the intersection of natural resources and traditional practices.
49) Indian:
Indian refers to anything related to India, including its diverse culture and rich traditions in medicine. The term signifies the indigenous practices, including Siddha, which draws on local resources, beliefs, and knowledge for health and well-being.
50) Pittam (Pittham):
Pitham is one of the three vital humors in Siddha medicine, representing metabolic processes and transformation. Understanding Pitham is crucial for diagnosing and treating health conditions, as imbalance in this humor can lead to various ailments, emphasizing holistic diagnostics.
51) Madra:
Madra is often associated with Madras (Chennai) in India, reflecting the city's significance in traditional medicinal practices. It illustrates the connection between local culture and the medicinal knowledge that has thrived in this urban environment.
52) Field:
Field denotes an area of study or expertise. Within the context of Siddha medicine, 'field' highlights the discipline's focus on traditional herbal remedies and holistic health methods, representing a significant aspect of India’s medical heritage.
53) Glass:
Glass refers to a material used for containers or storage. In Siddha medicine, glass containers are essential for preserving the integrity of herbal formulations, ensuring that they maintain potency and efficacy without contamination from external elements.
54) Water:
Water is a vital component necessary for life and is often used as an adjuvant in traditional medicine preparations. In Siddha, warm water is recommended with certain herbal formulations to enhance absorption and therapeutic effects, emphasizing the importance of hydration for health.
55) Table:
Table refers to a systematic display of information. In the context of the review, tables present ingredient quantities and their respective properties clearly, aiding in the understanding and application of Siddha formulations for practitioners and researchers alike.
56) Cukku:
Sukku refers to dried ginger, a spice known for its medicinal benefits, particularly digestive support. In Siddha formulations, sukku plays an integral role in enhancing the therapeutic effects, emphasizing the value of familiar herbs in traditional healing practices.
57) Devi:
Devi is a Sanskrit term for goddess, representing the feminine divine energy. In Siddha contexts, it can refer to practitioners or figures who embody healing qualities, bridging spirituality and medicinal practices for holistic health.
58) Food:
Food refers to substances consumed for nourishment. In Siddha medicine, dietary principles are integral, as they explore the connection between food choices and health, promoting the use of natural ingredients for disease prevention and wellness enhancement.
59) Tree:
Tree represents a towering plant vital to ecosystems and the source of many medicinal ingredients. In Siddha medicine, trees contribute numerous herbs with healing properties, reinforcing the link between natural habitats and traditional healing practices.
60) Fire:
Fire symbolizes transformation and energy in various cultures. In Siddha medicine, it is linked to the digestive fire (Agni), which is crucial for healthy metabolism and digestion, framing the importance of internal energetic processes in health management.
61) Pain:
Pain is an unpleasant sensory experience often indicating underlying health issues. Siddha medicine aims to address pain through a holistic approach, utilizing natural remedies that target the cause rather than just alleviating symptoms of discomfort.
62) Shand (Sand):
Sand represents the fine particles found in nature, which can also hold historical significance in traditional practices. Its relevance could extend to discussing textures of specific herbal powders used in Siddha formulations, affecting the application and absorption of medicines.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Review of Manimandhirathi Chooranam for acid peptic disorders.’. Further sources in the context of Science might help you critically compare this page with similair documents:
Terminalia chebula, Zingiber officinale, Piper longum, Carum copticum, Rock salt, Cuminum cyminum, Phytochemical, Siddha medicine, Pharmacological properties, Phyto-pharmacological review, Drug administration, Herbomineral formulation, Oral route, Antiulcer activity, Phytochemical properties, Peptic ulcer disease, Gastrointestinal health, Adjuvant, Chemical constituent, Piper nigrum, Digestive disorder.
Concepts being referred in other categories, contexts and sources.