Pippali's role as an immuno-modulator in lung cancer patients.

| Posted in: Health Sciences Science

Journal name: World Journal of Pharmaceutical Research
Original article title: Role of pippali (piper longum) as an immuno- modulator in the patient of lung cancer
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
This page presents a generated summary with additional references; See source (below) for actual content.

Original source:

This page is merely a summary which is automatically generated hence you should visit the source to read the original article which includes the author, publication date, notes and references.

Author:

Dr. Rakesh Kumar Bakolia, Dr. Sharad Maroti Porte and Dr. Ritika


World Journal of Pharmaceutical Research:

(An ISO 9001:2015 Certified International Journal)

Full text available for: Role of pippali (piper longum) as an immuno- modulator in the patient of lung cancer

Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research

Doi: 10.20959/wjpr202315-29725

Copyright (license): WJPR: All rights reserved


Download the PDF file of the original publication


Summary of article contents:

Introduction

Lung cancer is a significant global health concern, ranking as the second leading cause of cancer-related deaths, with 1.7 million fatalities reported in 2018. The Ayurvedic system of medicine offers a variety of treatments, including substances known as Rasayana, which are believed to possess immune-modulatory properties. Among these, Pippali (Piper longum) is highlighted for its potential in supporting lung cancer patients. Pippali Rasayana, a formulation discussed by ancient Ayurvedic texts, is specifically recognized for its use in managing respiratory ailments and could provide adjunctive support for lung cancer treatment.

Immune Modulation and Pippali

One of the central themes in the article is the immune-modulating effect of Pippali Rasayana. The immune system plays a crucial role in combating cancers and infections, and Rasayana therapies are designed to rejuvenate and support bodily functions, maintaining the balance of the body's elements or Dhatus. Pippali is characterized by its Katu Rasa (pungent taste) and Ushna Veerya (heating potency), making it an effective counter to the Kapha dosha, which is associated with heaviness and obstruction. Through its unique properties, Pippali can help restore balance in the body, potentially enhancing the immune response against lung cancer.

The Role of Ayurveda in Cancer Management

The article emphasizes how Ayurvedic principles can aid in diagnosing and managing lung cancer, particularly adenocarcinoma. It notes that the dushti (vitiation) of Pranavaha srotus (respiratory pathways) and an imbalance in Kapha dosha are commonly observed in lung cancer patients. The qualities of Kapha—cold, oily, and heavy—stand in opposition to the properties of Pippali. By targeting these imbalances, Pippali Rasayana may provide therapeutic benefits, functioning as an adjuvant treatment that enhances overall health during conventional cancer therapies.

Pharmacological Properties of Pippali

The article articulates the broad pharmacological benefits of Pippali, which have been recognized since ancient times in Ayurvedic literature. Traditionally, Pippali is regarded as having diverse therapeutic effects, including antioxidant, immunomodulatory, and antibacterial properties. It is prescribed for a variety of respiratory conditions, such as cough and tuberculosis. Scientific validations of these claims bolster the historical usage of Pippali within the Ayurvedic framework, supporting its relevance as a complementary approach for patients dealing with lung cancer and other respiratory diseases.

Conclusion

In conclusion, Pippali Rasayana presents a promising adjunctive therapy for lung cancer, especially when integrated with conventional treatment methods. Its ability to act as an immune modulator and rejuvenation agent aligns with Ayurvedic principles of promoting health and balance within the body. The article advocates for the inclusion of Pippali Rasayana in treatment regimens, highlighting its potential benefits during and after standard chemotherapy or other cancer treatments, ultimately aiming to enhance the quality of life for lung cancer patients.

FAQ section (important questions/answers):

What is the role of Pippali in lung cancer treatment?

Pippali Rasayana acts as an immune-modulator and antioxidant, beneficial in managing lung cancer symptoms, particularly adenocarcinoma. It helps balance the Kapha dosha and supports the respiratory system.

How prevalent is lung cancer worldwide?

Lung cancer is the second leading cause of cancer-related deaths globally, with approximately 1.7 million deaths reported in 2018, highlighting the need for effective treatment options.

What are Rasayana therapies in Ayurveda?

In Ayurveda, Rasayana therapies are rejuvenation treatments that promote optimal health by maintaining the balance of the body's seven dhatus and enhancing immune function.

What qualities differentiate Pippali from Kapha dosha?

Pippali possesses Katu Rasa and Ushna Veerya characteristics, which counteract the Sheeta and Snigdha qualities of Kapha dosha, making it effective in managing Kapha-related disorders.

What historical significance does Pippali have in Ayurveda?

Pippali has been utilized since the Vedic era for various ailments and is well-regarded in Ayurvedic texts for its immunomodulatory, antioxidant, and therapeutic properties.

Can Pippali be used alongside conventional cancer treatments?

Yes, Pippali Rasayana can be integrated into conventional lung cancer treatment plans, either during or after treatment, to enhance overall health and immune response.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Pippali's role as an immuno-modulator in lung cancer patients.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Pippali (Pippalin):
Pippali, or Piper longum, is a significant herb in Ayurveda known for its therapeutic properties. It is highlighted for its immunomodulatory, antioxidant, and antibacterial effects, making it valuable in treating respiratory diseases such as lung cancer and tuberculosis. Pippali supports respiratory health and overall rejuvenation.

2) Rasayana (Rasa-ayana):
Rasayana refers to the rejuvenation therapies in Ayurveda that promote vitality and longevity. These treatments enhance the body's immune system, balance the doshas, and restore the Sapta dhatus (seven tissues). Rasayana therapies are believed to improve health, resistance to disease, and overall well-being.

3) Cancer:
Cancer is a group of diseases characterized by uncontrolled cell growth and proliferation, leading to potential invasion of adjacent tissues. Lung cancer is particularly concerning, being one of the leading causes of cancer-related deaths globally. Treatment approaches may integrate traditional and modern medical practices.

4) Kapha:
Kapha is one of the three doshas in Ayurveda, representing earth and water elements. It is associated with stability, structure, and lubrication in the body. Imbalances in Kapha can lead to respiratory issues, obesity, and other conditions, making it essential to maintain Kapha balance for optimal health.

5) Nighantu (Nighamtu):
Nighantu refers to an Ayurvedic lexicon or glossary of medicinal plants and their properties. Various Nighantus categorize herbs based on their uses, benefits, and effects on the body. They are essential for Ayurvedic practitioners to reference herbological knowledge and ensure proper diagnosis and treatment.

6) Rasa (Rasha):
Rasa signifies the taste or essence of a substance in Ayurvedic medicine. It plays a crucial role in determining how a drug interacts with the body. Each rasa corresponds to specific therapeutic effects, influencing the treatment strategy employed for various diseases and conditions.

7) Guru:
Guru is an important quality in Ayurveda that denotes heaviness. Substances with guru properties are often nourishing, grounding, and calming. In practice, recognizing guru qualities of herbs helps in creating balanced formulations for patients based on their unique doshic imbalances and health conditions.

8) Snigdha:
Snigdha represents the quality of being unctuous or oily. It is beneficial in Ayurvedic treatments for providing nourishment, lubrication, and moisture in the body. This quality is particularly useful for counteracting dryness and is indicated for treating certain respiratory and digestive disorders.

9) Kasa (Kasha):
Kasa, or cough, is a symptom rather than a disease in Ayurveda, often linked to vitiated Kapha dosha. Effective treatments aim to balance the doshas, alleviate coughing, and restore respiratory health. Ayurvedic approaches for kasa include herbal remedies and lifestyle modifications.

10) Drug:
Drugs in Ayurveda are natural compounds derived from plants, minerals, and other sources. These drugs are employed for their therapeutic properties, playing a pivotal role in treatments aligned with the principles of balancing the doshas and restoring health.

11) Katurasa (Katu-rasa):
Katu-rasa refers to the pungent taste, which is known to stimulate digestion and possess expectorant properties. In Ayurveda, substances with katu-rasa can be effective in alleviating respiratory conditions, promoting appetite, and enhancing metabolic functions while balancing doshas involved in various ailments.

12) Ayurveda (Ayus-veda):
Ayurveda is an ancient Indian system of medicine focusing on holistic healing and balance in physical, mental, and spiritual aspects of life. It emphasizes preventative care, the management of lifestyle, dietary habits, and the use of herbal medicine to promote overall health and well-being.

13) Ushna (Usna):
Ushna denotes the quality of heat or warmth in Ayurveda. This characteristic is important in treatments aimed at enhancing metabolism and digestion. Ushna substances help offset cold conditions and can be particularly useful for disorders linked with Kapha imbalances.

14) Katu:
Katu refers to the pungent taste and has several medicinal properties, such as stimulating appetite and reducing mucus. In Ayurvedic treatment, drugs possessing katu qualities serve to manage conditions associated with Kapha dosha and stimulate digestive fire (Agni).

15) Guna:
Guna translates to quality or attribute in Ayurveda. Each herb possesses specific gunas that determine its effects on the body and mind. Recognizing these gunas helps practitioners personalize treatment plans according to a patient's individual composition and health issues.

16) Madhurarasa (Madhura-rasa):
Madhura-rasa represents the sweet taste, known for its nourishing and calming properties. It balances the body and is often indicated in treatments for various conditions, enhancing emotional stability and contributing to overall health alongside other taste profiles.

17) Kaphadosha (Kaphadosa, Kapha-dosha):
Kapha-dosha is one of the three fundamental energies in Ayurveda, characterized by qualities of heaviness, coldness, and moisture. An imbalance in Kapha can lead to various health issues, often necessitating treatments that include herbal remedies, dietary recommendations, and lifestyle changes.

18) Science (Scientific):
Scientific approaches in Ayurvedic research involve validating traditional practices through modern methodologies, including pharmacological studies and clinical trials. This integration helps bridge the gap between ancient knowledge and contemporary medicine, enhancing the credibility of herbal remedies and treatments.

19) Madhura:
Madhura, meaning sweet, is also known for its beneficial effects on the body. It helps balance other tastes and can soothe digestive tract irritations while promoting overall harmony, reflected in various remedies and preparations throughout Ayurvedic practice.

20) Disease:
Diseases in Ayurveda are viewed as manifestations of dosha imbalances, emphasizing the holistic approach to treatment and prevention. Each disease is understood through its physical, emotional, and environmental influences, leading to personalized care strategies.

21) Tantra (Tantrism, Tamtra):
Tantra, in Ayurveda, often refers to specialized knowledge or techniques for practicing health care. It includes the methodologies and principles governing the healing systems, enabling practitioners to apply traditional wisdom in a systematic and effective manner.

22) Dosha (Dosa):
Dosha refers to the three primary energies—Vata, Pitta, and Kapha—believed to govern physiological and psychological processes. An individual's health is contingent on the balance of these doshas, with imbalances leading to various health issues that Ayurveda seeks to correct.

23) Ardra:
Ardra typically signifies moisture or wetness in Ayurveda, particularly in the context of herbal preparations. It can indicate a certain quality of Pippali, as well as its relevance in treating disorders associated with dryness and vitiated Kapha, promoting balance in the body.

24) Dhatu:
Dhatus refer to the fundamental tissues of the body categorized in seven groups that represent vital aspects of life. Each dhatu influences overall health, and treatment strategies often aim to nourish and balance these tissues to ensure optimal function.

25) Sapta (Saptan, Shapta):
Sapta denotes the number seven in Sanskrit. In the context of Ayurveda, it is often mentioned in relation to the Sapta dhatus (seven tissues), providing a framework for understanding the body’s structure and functioning, essentially guiding restorative and healing processes.

26) Arshas (Arsa, Arsas, Arsha):
Arsha refers to hemorrhoids in Ayurveda, characterized by vascular disturbances in the anal region. Ayurvedic treatment focuses on restoring balance within the body through dietary changes, herbal medications, and lifestyle modifications addressing both physical symptoms and underlying imbalances.

27) Fever:
Fever, or Jvara in Ayurveda, represents an elevation in body temperature typically indicative of an underlying imbalance or infection within the body. Ayurvedic treatment for fever involves balancing the doshas and may include herbal remedies, dietary modifications, and lifestyle adjustments.

28) Piper longum:
Piper longum, known as Pippali, is an important herb in Ayurveda renowned for its medicinal properties, including its ability to support respiratory health, enhance digestion, and act as an immunomodulator. It is commonly used to treat cough, asthma, and various respiratory ailments.

29) Tuberculosis:
Tuberculosis (TB) is a bacterial infection primarily affecting the lungs, associated with respiratory symptoms. Ayurvedic treatment may involve herbs like Pippali, which are believed to enhance respiratory function and provide supportive care, while addressing underlying imbalances in the body.

30) Vatahara (Vata-ahara):
Vatahara indicates the property or quality of reducing Vata dosha. In Ayurveda, substances with Vatahara qualities help alleviate symptoms associated with excess Vata, such as anxiety, dryness, and respiratory conditions, promoting overall balance in the body.

31) Samhita:
Samhita refers to a compilation of texts in Ayurveda containing essential knowledge regarding diseases, treatments, and herbal formulations. Key texts like Charaka Samhita and Sushruta Samhita serve as foundational resources, guiding practitioners in effective Ayurvedic practices.

32) Vrishya (Vrsya):
Vrishya pertains to aphrodisiac properties in Ayurveda, indicating substances that enhance reproductive health and vitality. Herbs with Vrishya qualities are often included in formulations aimed at improving fertility and sexual health.

33) Kushtha (Kustha):
Kushtha refers to skin diseases in Ayurveda, which are often treated with specific herbal remedies and lifestyle changes aimed at restoring balance and addressing underlying doshic imbalances causing skin disturbances.

34) Medhya:
Medhya denotes substances that enhance cognitive function and mental clarity in Ayurveda. These ingredients promote brain health, improve memory, and support overall mental faculties, playing an important role in holistic health.

35) Vyadhin (Vyadhi):
Vyadhi translates to disease or disorder in Ayurveda, encompassing various health conditions arising from dosha imbalances. Diagnosis and treatment focus on identifying the root cause of Vyadhi for effective management and restoration of health.

36) Pitta:
Pitta is one of the three doshas in Ayurveda, symbolizing fire and heat. It regulates digestion, metabolism, and transformation processes. Imbalances in Pitta can lead to various health issues, necessitating adjustments in diet, lifestyle, and treatment approaches.

37) Udara:
Udara denotes abdominal disorders in Ayurveda, often linked to digestive issues or imbalances within the body's systems. Ayurvedic treatment for udara focuses on restoring balance through dietary changes, herbal remedies, and lifestyle modifications.

38) Gulma:
Gulma refers to a medical condition characterized by abdominal masses or growth. Ayurveda addresses gulma by identifying underlying dosha imbalances and employing herbal treatments aimed at normalizing tissue health and reducing appropriate symptoms.

39) Kumar:
Kumar translates to child or young individual in Sanskrit. In Ayurveda, understanding the unique physiological and psychological attributes of children is essential for providing appropriate care and treatments that promote growth and development.

40) Death:
Death signifies the cessation of life processes. In Ayurveda, understanding the nature of death and the life cycle encourages a holistic approach to health, encouraging prevention and wellness measures that enhance longevity and quality of life.

41) Human body:
The human body is viewed as a complex system in Ayurveda, comprised of physical, mental, and spiritual elements. Achieving balance among these elements ensures health and vitality, forming the foundation of Ayurvedic practices and treatment methodologies.

42) Dhanvantarinighantu (Dhanvantari-nighantu):
Dhanvantari-nighantu is a classical Ayurvedic text detailing medicinal plants and their applications. It serves as a vital reference for practitioners to understand herbal properties and formulate treatments tailored to their patients' needs.

43) Sushruta-samhita (Susruta-samhita):
Sushruta-samhita is one of the foundational texts of Ayurveda, encompassing surgical techniques, anatomical knowledge, and treatment protocols. Its comprehensive approach to medicine creates a strong basis for surgical practices and holistic patient care.

44) Ashtangahridaya (Astangahrdaya, Ashtanga-hridaya):
Ashtanga-hridaya is a key Ayurvedic text authored by Vagbhata, bridging the teachings of Charaka and Sushruta. This text systematically organizes Ayurvedic concepts and provides comprehensive insights into health, disease, and holistic healing practices.

45) Pharmacological:
Pharmacological studies in Ayurveda investigate the actions and effects of herbal medicines on biological systems. Through research, the pharmacological basis of traditional remedies is unveiled, aligning ancient wisdom with modern scientific understanding and practices.

46) Antibiotic (Antibacterial):
Antibacterial properties in Ayurvedic herbs refer to their ability to inhibit bacterial growth. Many Ayurvedic plants exhibit these properties, making them effective in treating infections and enhancing overall immunity within traditional healthcare practices.

47) Pharmacology:
Pharmacology is the scientific study of drugs, their properties, effects, and modes of action. Understanding pharmacology within Ayurveda facilitates the integration of traditional medicine with modern scientific methodologies, enhancing the credibility and efficacy of herbal treatments.

48) Dhanvantari (Dhanvamtari):
Dhanvantari is regarded as the ancient god of medicine and an avatar of Vishnu in Hindu tradition. His teachings and contributions to Ayurvedic medicine emphasize the importance of healing and the wise use of natural substances for health.

49) Saptadhatu (Sapta-dhatu, Saptan-dhatu):
Sapta-dhatu signifies the seven bodily tissues in Ayurveda, crucial for understanding health. These include Rasa, Rakta, Mamsa, Meda, Asthi, Majja, and Sukra, and addressing imbalances among these tissues is vital for overall health and wellness.

50) Vajikarana:
Vajikarana refers to the aspect of Ayurveda focused on enhancing reproductive health, vitality, and sexual wellness. Treatments aimed at Vajikarana may involve specific herbs and dietary recommendations to improve strength and vitality.

51) Discussion:
Discussion in the context of Ayurveda promotes the exploration of ideas and concepts related to health, treatments, and practices. Engaging in discussion facilitates a better understanding of traditional knowledge and encourages the synthesis of contemporary methodologies with ancient wisdom.

52) Substance:
A substance in Ayurveda signifies any material used in medicinal formulations. Recognizing the properties and effects of each substance is essential for creating effective treatment plans tailored to individual patient needs and conditions.

53) Suffering:
Suffering in Ayurveda is associated with imbalances in doshas and can manifest as physical or psychological distress. Addressing the root cause of suffering through comprehensive healing strategies is central to Ayurvedic practice, focusing on prevention and restoration of balance.

54) Vitiation (Vitiated):
Vitiation refers to the alteration or disturbance of normal physiological processes or dosha balances. In Ayurveda, understanding vitiation helps diagnose diseases and apply effective treatments aimed at restoring the original equilibrium.

55) Pliharoga (Pliha-roga):
Pliharoga refers to a specific ailment related to the spleen or related organs in Ayurveda. Recognition of this condition involves diagnosing the underlying dosha imbalances and employing appropriate treatments to restore health.

56) Medoroga (Medas-roga):
Medoroga signifies a condition related to obesity and metabolic disorders in Ayurveda. Treatment focuses on balancing the doshas through lifestyle modifications, dietary changes, and herbal remedies to promote healthy weight management.

57) Ashtanga (Astanga, Ashtan-anga):
Ashtanga refers to the eight branches of Ayurveda, encompassing various fields like internal medicine, surgery, pediatrics, and gynecology. This classification aids practitioners in understanding the comprehensive structure and applications of Ayurvedic medicine.

58) Medicine:
Medicine in Ayurveda encompasses natural therapies and techniques employed to enhance health and treat ailments. This includes herbal treatments, dietary regimens, therapeutic practices, and lifestyle modifications grounded in the principles of balance and holistic wellness.

59) Activity:
Activity in Ayurveda reflects the dynamic state of bodily functions and movements. Maintaining a healthy balance of activities is crucial for physical and mental well-being, influencing overall vitality and quality of life.

60) Sanskrit:
Sanskrit is the classical language of ancient Indian texts, including Ayurvedic literature. Proficiency in Sanskrit is essential for Ayurvedic practitioners to accurately interpret and convey traditional teachings, ensuring the preservation of knowledge.

61) Hridaya (Hrdaya):
Hridaya signifies the heart and is often associated with emotional and mental well-being in Ayurveda. The health of the heart is vital for physical health and emotional balance, making it an important focus in holistic healing practices.

62) Prameha:
Prameha refers to a group of metabolic disorders related to excessive urination and diabetes in Ayurveda. Treatment strategies typically involve dietary adjustments and herbal remedies aimed at balancing the doshas and restoring metabolic health.

63) Anushna (Anusna):
Anushna refers to a quality of being non-heated or cool in Ayurveda, pertinent when considering the effects of substances or foods on the body's dosha balance. Understanding Anushna helps practitioners formulate appropriate treatments for patients.

64) Account:
Account in Ayurveda relates to documentation and understanding of various conditions and treatments. Detailed accounts of practices and results contribute to the body of knowledge, supporting the evolution of Ayurvedic medicine.

65) Sharad (Sarad):
Sharad generally refers to the autumn season in Ayurveda, which is considered significant for various health practices. Seasonal changes may influence doshic imbalances, prompting specific dietary and lifestyle adjustments to maintain balance and well-being.

66) Vipaka:
Vipaka signifies the post-digestion taste and effects of food in Ayurveda, influencing how substances impact the body over time. Understanding vipaka is essential for determining dietary recommendations and therapeutic applications.

67) Madhu:
Madhu signifies sweetness and is often associated with honey in Ayurveda, valued for its health benefits. It is commonly used in formulations to enhance flavor and assist in various therapeutic processes.

68) Karma (Karman):
Karma in Ayurveda signifies action or effect, reflecting the interconnectedness of one's actions and their impact on health and well-being. This concept emphasizes the holistic approach that Ayurveda takes in linking physical, mental, and spiritual aspects of life.

69) Jvara:
Jvara refers to fever in Ayurveda, acknowledged as a sign of disturbance in the body. It is addressed through specific treatments aimed at restoring balance and mitigating symptoms, ultimately focusing on the underlying causes of the febrile condition.

70) Laghu:
Laghu indicates lightness in Ayurveda, often associated with substances that facilitate digestion and promote overall vitality. Recognizing laghu qualities in herbs helps in tailoring treatments to counterbalance excess heaviness within the body.

71) Rakta:
Rakta refers to the blood tissue within the Sapta dhatus, vital for sustenance and circulation in the body. Maintaining healthy rakta is essential for overall well-being, and imbalances often require targeted interventions to restore harmony.

72) Yukta:
Yukta conveys the notion of being balanced or suitable. In Ayurveda, the concept of yukta emphasizes the importance of selecting appropriate treatments and dietary practices tailored to an individual's constitution and health profile for effective healing.

73) Virya:
Virya relates to the potency or strength of a substance in Ayurveda. Understanding virya is fundamental to Ayurvedic treatments, as it influences how a drug acts in the body and its efficacy concerning various doshic contexts.

74) Hikka:
Hikka refers to hiccups, often viewed as a symptom of digestive disturbance in Ayurveda. Effective treatments may involve dietary adjustments and herbal remedies aimed at balancing the doshas to restore normal function.

75) Veda:
Vedic refers to the ancient texts and traditions of India, including Ayurveda. Understanding Vedic principles is crucial for engaging with Ayurvedic practices and integrating traditional wisdom into contemporary medical applications.

[Note: The above list is limited to 75. Total glossary definitions available: 78]

Other Science Concepts:

[back to top]

Discover the significance of concepts within the article: ‘Pippali's role as an immuno-modulator in lung cancer patients.’. Further sources in the context of Science might help you critically compare this page with similair documents:

Saptadhatu, Dhanvantarinighantu, Katurasa, Ayurvedic principle, Rasayana therapy, Antioxidant properties, Acharya Charaka, Clinical experience, Ushna veerya, Rasayana drug, Ayurvedic classical text, Pippali Properties, Rasayan Therapy, Kaph Dosha, Malignant disease, Lung cancer, Pippali Rasayana, Anti-inflammatory qualities, World Journal of Pharmaceutical Research.

Let's grow together!

I humbly request your help to keep doing what I do best: provide the world with unbiased sources, definitions and images. Your donation direclty influences the quality and quantity of knowledge, wisdom and spiritual insight the world is exposed to.

Let's make the world a better place together!

Like what you read? Help to become even better: