Critical review on therapeutic and toxicological aspect of upvisha

jayapala (croton tiglium)

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Journal name: World Journal of Pharmaceutical Research
Original article title: Critical review on therapeutic and toxicological aspect of upvisha
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Subtitle: jayapala (croton tiglium)

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Author:

Dr. Arvind Tumram and Dr. Kundan Meshram


World Journal of Pharmaceutical Research:

(An ISO 9001:2015 Certified International Journal)

Full text available for: Critical review on therapeutic and toxicological aspect of upvisha

Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research

Doi: 10.20959/wjpr20223-23454

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Summary of article contents:

Introduction

Ayurveda is an ancient system of medicine that encompasses various branches, including Agadtantra, which focuses on the diagnosis and management of poisoning. Among the cornerstone medicinal sources in Ayurveda is the plant Croton tiglium, commonly known as Jayapala or Jamalgota. This review aims to elaborate on the therapeutic and toxicological aspects of Jayapala, emphasizing its significance in Ayurvedic practice and its remarkable properties, while also highlighting the associated risks of its usage if improperly processed.

The Therapeutic Versatility of Jayapala

Jayapala (Croton tiglium) is classified as an upavisha, a category of plants in Ayurveda recognized for their therapeutic uses despite their toxic properties. The seeds are particularly potent and are known for their effectiveness as a strong laxative, aiding in conditions of persistent constipation. The plant's medicinal versatility is illustrated by its presence in numerous Ayurvedic formulations such as Icchabhedi Rasa and Jwarahari Rasa, which utilize Jayapala after a meticulous purification process known as Shodhana. This process is essential for reducing the plant's inherent toxicity, ensuring that it can be safely employed in various medicinal treatments.

Toxicological Concerns

Despite its therapeutic potential, the seeds and oil of Jayapala are extremely toxic and can lead to severe health complications. A critical aspect of its toxicity is attributed to the presence of crotin, a toxalbumin that can disrupt protein synthesis in cells. Symptoms of poisoning can manifest quickly, with adverse reactions such as intense abdominal pain, vomiting, and, in severe cases, may lead to death within hours. This emphasizes the need for rigorous safety measures and awareness about the conditions of administration, particularly regarding dosages and the requirement for proper purification techniques before use.

The Importance of Shodhana in Ayurveda

The concept of Shodhana is pivotal in Ayurveda, particularly in the context of using plants like Jayapala that possess toxic properties. This purification process may involve boiling the seeds in cow’s milk or other traditional methods to mitigate their toxic effects significantly. Historical texts such as the Charaka Samhita advocate for the purification of potent plant-based substances, suggesting that without this intricate process, the harmful effects can overshadow any potential benefits. Understanding and implementing Shodhana not only enhances the safety and efficacy of Ayurvedic treatments but also underscores the holistic approach of Ayurveda in managing health through natural substances.

Conclusion

In conclusion, Jayapala (Croton tiglium) plays a dual role in Ayurvedic medicine, providing both therapeutic potential and serious health risks due to its toxicity. The application of rigorous processes such as Shodhana is essential to harness its benefits safely. As the global inclination towards natural remedies grows, the importance of proper preparation and understanding of medicinal plants like Jayapala cannot be overstated. Continued research and adherence to Ayurvedic principles will be vital for the safe integration of such potent herbs into contemporary health practices.

FAQ section (important questions/answers):

What is Jayapala and its scientific name?

Jayapala, known scientifically as Croton tiglium, is an Ayurvedic plant categorized as an upavisha, which has toxic properties but is still used in traditional medicine.

How does Ayurveda classify toxic plants like Jayapala?

In Ayurveda, toxic plants, including Jayapala, are categorized as visha (poison) and upavisha (toxins that are not lethal). They are further classified by their toxicity levels and effects.

What therapeutic uses does Jayapala have in Ayurveda?

Jayapala is primarily used as a powerful laxative and for treating various abdominal disorders. It requires careful preparation and dosage to manage its toxic effects.

What are the symptoms of Jayapala poisoning?

Symptoms of Jayapala poisoning include burning pain from mouth to stomach, nausea, vomiting, purging, bloody stools, vertigo, and can lead to circulatory and respiratory collapse.

What purification methods are used for Jayapala before use?

Jayapala undergoes shodhana, a purification process, involving boiling the seeds in cow's milk and drying them, which helps reduce its toxicity for safe medicinal use.

What are the major pharmacological properties of Croton tiglium?

Croton tiglium has diverse pharmacological properties, including purgative, anti-inflammatory, vermifuge, diaphoretic, and it also exhibits antimicrobial and antioxidant activities.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Critical review on therapeutic and toxicological aspect of upvisha”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Jayapala (Jaya-pala):
Jayapala, scientifically known as Croton tiglium, is a medicinal plant recognized in Ayurveda. It is classified as an upavisha (toxic but not lethal) and is utilized for its purgative properties. Purification processes (shodhana) are essential for its safe medical use. Its extracts can treat various disorders when appropriately processed.

2) Rasa (Rasha):
Rasa refers to the taste or flavor of a substance in Ayurvedic medicine. It represents the essential qualities that influence the therapeutic effect of a drug. Different rasas (like katu - bitter, madhura - sweet) are prescribed for specific conditions, guiding practitioners in selecting appropriate treatments for patients.

3) Croton tiglium:
Croton tiglium, commonly known as Jayapala, is a plant from the Euphorbiaceae family. Its seeds contain bioactive compounds, making it toxic if unprocessed. However, it also serves therapeutic purposes in Ayurveda, particularly for constipation and detoxification. Proper purification is necessary to reduce its inherent toxicity for safe use.

4) Visha (Visa):
Visha translates to poison in Ayurveda, encompassing substances that can cause harm or adverse effects to health. Ayurvedic texts categorize visha into sthavara (plant-based poisons), jangama (animal poisons), and kritrima (artificial poisons). Understanding visha is vital for developing detoxification strategies in Ayurvedic practice.

5) Medicine:
Medicines in Ayurveda encompass a wide range of natural substances used to treat ailments, including herbal formulations, mineral compounds, and dietary recommendations. The focus is on holistic healing, considering individual constitution and promoting balance among the doshas for overall health.

6) Lepa:
Lepa refers to a topical application or paste used in Ayurvedic treatments. It can be made from various herbal ingredients and applied on the skin to treat wounds, inflammation, or skin conditions. Lepas leverage the therapeutic properties of the herbs absorbed through the skin for localized benefits.

7) Activity:
Activity in pharmacology refers to the biological effects a substance produces in living organisms. In the context of medicinal plants like Jayapala, its activity relates to therapeutic effects, such as laxative effects due to its bioactive compounds. Understanding these activities helps formulate effective treatment strategies.

8) Ayurveda (Ayus-veda):
Ayurveda is an ancient Indian system of medicine that focuses on holistic health through balance among body, mind, and spirit. It combines philosophy, natural remedies, and lifestyle practices. Ayurveda emphasizes individualized treatment plans, using herbs, diet, detoxification practices, yoga, and meditation to enhance health and well-being.

9) Jala:
Jala means water in Sanskrit and plays a critical role in Ayurveda for detoxification and purification processes. Water is often used as an anupana (vehicle) to administer herbal medicines. It is also essential in various formulations and therapeutic practices for hydration and cleansing the body.

10) Nighantu (Nighamtu):
Nighantu refers to Ayurvedic pharmacopoeias or lexicons that enumerate and describe the medicinal properties of plants, minerals, and other substances. These texts serve as reference guides for practitioners to understand the therapeutic applications, preparation methods, and potential effects of various herbs and compounds used in Ayurveda.

11) Shodhana (Sodhana):
Sodhana emphasizes the purification processes integral in Ayurveda, especially for potentially toxic substances. This practice ensures that medications are made safe for use, preserving their efficacy while reducing any harmful side effects, thus reinforcing the system's commitment to holistic healing.

12) Sthana:
Sthana refers to localized areas of pathology or specific body regions targeted in Ayurvedic treatments. In the context of visha (poison), sthana is particularly relevant for understanding how poisons affect different organs and how targeted treatments can alleviate localized symptoms resulting from toxicity.

13) Toxicology:
Toxicology is the study of the adverse effects of substances on living organisms. In Ayurveda, understanding toxicology is vital for safely applying potentially harmful plants such as Jayapala, enabling practitioners to employ antidotes and purification processes effectively to mitigate toxicity and promote healing.

14) Pippali (Pippalin):
Pippali, or long pepper, is an important herb in Ayurveda, known for its carminative and digestive properties. It is often used as an ingredient in formulations to enhance bioavailability and absorption of other herbs. Its role in traditional remedies showcases its importance in balancing bodily functions.

15) Toxicity:
Toxicity refers to the degree to which a substance can harm living organisms. In Ayurveda, understanding toxicity helps practitioners manage the risks associated with using medicinal plants like Jayapala. Proper processing and dosages are critical to ensuring safety while maximizing therapeutic benefits.

16) Parada:
Parada, or mercury, plays a significant role in Ayurvedic alchemy (rasa shastra). When processed correctly, it can enhance the efficacy of various formulations. Parada is considered potent but also requires careful handling due to its inherent toxicity, necessitating thorough purification before use.

17) Upavisha (Upavisa):
Upavisha refers to substances categorized as toxic but not lethal to humans in Ayurveda. These substances, like Jayapala, can cause adverse effects but are used in controlled amounts after purification. Upavisha demonstrates the Ayurvedic principle of utilizing potentially harmful plants in therapeutic contexts under specific guidelines.

18) India:
India is the birthplace of Ayurveda, where ancient medical systems and philosophies originated. The diverse botanical wealth of India has contributed significantly to herbal medicine practices, integrating local knowledge and cultural healings with modern scientific approaches, making India a hub for traditional and alternative medicine.

19) Drug:
In Ayurveda, drugs encompass a wide range of substances used for therapeutic purposes. This includes all forms of natural products like herbs, minerals, and animal derivatives. Ayurvedic drug formulations are based on ancient texts, emphasizing the importance of purity, dosage, and individual patient conditions for effective treatment.

20) Gandhaka (Gamdhaka):
Gandhaka, or sulfur, is an important component in Ayurvedic formulations. It is utilized for its benefits in skin conditions and detoxification. Proper processing is essential to enhance its therapeutic properties while minimizing potential side effects, showcasing Ayurveda’s emphasis on purification in using minerals for health.

21) Tankana (Tamkana):
Tankana refers to borax, a substance used in Ayurveda for its cleansing and purifying properties. It is often used in formulations for various skin disorders and to enhance the detoxifying effects of other ingredients. Its correct preparation and dosage are critical to ensuring safe therapeutic applications.

22) Pain:
Pain is a complex physiological and emotional experience that Ayurveda addresses through various modalities. Ayurvedic treatments focus on understanding the root causes of pain, considering factors like dosha imbalance and utilising herbal remedies, dietary changes, and lifestyle modifications to alleviate discomfort holistically.

23) Jamalgota:
Jamalgota is another name for Croton tiglium, referring to the seeds of the plant known for their potent purgative properties. While they are toxic, properly processed formulations are used in Ayurveda for treating constipation. Understanding how to use Jamalgota safely is crucial in Ayurvedic practice.

24) Anjana (Amjana):
Anjana refers to eye medications in Ayurveda, often involving herbal preparations that are applied topically to the eye. These remedies are believed to enhance vision and provide relief from various ocular conditions. Anjana showcases Ayurveda's holistic approach to healthcare, which encompasses various sensory organs.

25) Madhu:
Madhu means honey in Sanskrit and is widely used in Ayurveda as a natural sweetener and medicinal agent. It possesses various therapeutic properties and is often employed as a vehicle for herbal formulations, enhancing the effectiveness and palatability of medicines given to patients.

26) Danti (Damti, Dantin):
Danti refers to the medicinal plant commonly known as ‘Euphorbia’ and is classified under Sthavara visha. Its root is believed to have purgative effects, while its properties must be carefully monitored during usage. In Ayurveda, Danti is valued for its therapeutic applications and needs appropriate preparatory processes.

27) Varga:
Varga refers to categories or classifications within the Ayurvedic pharmacopoeia. It helps in organizing herbs, substances, or formulations according to their properties and therapeutic effects. Understanding vargas enables practitioners to select appropriate remedies while considering the unique qualities of each ingredient used in therapies.

28) Sutrasthana (Sutra-sthana):
Sutrasthana is one of the sections of the Ayurvedic texts like Charaka Samhita that outlines fundamental principles and basic concepts of Ayurveda. It serves as a guide for practitioners in understanding key therapeutic approaches, disease prevention, and management, emphasizing lifestyle and dietary considerations for optimal health.

29) Triphala (Tri-phala):
Triphala is an Ayurvedic formulation comprising three fruits: Amalaki, Haritaki, and Bibhitaki. Known for its detoxification, digestive, and rejuvenating properties, it is utilized widely for its balancing effects on all three doshas. Triphala exemplifies the synergy of combining different plant medicines for comprehensive health benefits.

30) Sanskrit:
Sanskrit is the classical language of ancient Indian literature, including Ayurvedic texts. It serves as the foundation for the terminology used in Ayurveda, encompassing key concepts, principles, and therapeutic formulations. Understanding Sanskrit is essential for those studying traditional medicine to accurately interpret ancient wisdom.

31) Disease:
In Ayurveda, a disease is seen as an imbalance within the individual that disrupts normal physiological functions. Diagnosing the underlying causes of disease involves evaluating the interplay of doshas, dhatus, and malas. Treatment strategies are adapted to restore balance through natural means, emphasizing prevention.

32) Ashtanga (Astanga, Ashtan-anga):
Astanga refers to the eight branches or disciplines of Ayurveda, encompassing various aspects of health and medicine. These include disciplines like Agadtantra (toxicology), Shalya (surgery), and K Ayurveda (general medicine). Astanga outlines the breadth of Ayurvedic practice, highlighting the comprehensive approach to health.

33) Science (Scientific):
Sciences encompass the systematic study of natural phenomena, promoting understanding and innovation. In Ayurvedic contexts, bridging traditional knowledge with scientific inquiry supports the validation and evolution of herbal practices, enhancing their credibility and effectiveness in contemporary healthcare.

34) Marica:
Marica, or black pepper, is utilized in Ayurveda for its digestive and stimulating properties. It enhances the bioavailability of other therapeutic agents and is commonly included in formulations. Its incorporation into Ayurvedic remedies exemplifies the integration of spices into medicine for enhanced health effects.

35) Family:
Family, in the botanical sense, refers to a group of related plants classified under a common category. Understanding plant families is crucial in Ayurveda for identifying medicinal properties and uses based on shared characteristics. This aids in the systematic organization of herbal resources for therapeutic application.

36) Tamra:
Tamra, or copper, is used in Ayurvedic formulations for its therapeutic benefits. It is believed to have properties that enhance digestion and detoxification. As a metal, its proper processing is vital to ensure safety and efficacy in medicinal applications, reinforcing Ayurveda’s emphasis on substance purity.

37) Death:
Death is viewed as a natural phase in Ayurveda, closely connected to the balance of the body’s doshas and overall health. Ayurvedic practices aim at promoting longevity while recognizing the inevitability of death. Understanding the factors contributing to health and disease can improve life quality.

38) Hara:
Hara generally refers to something that takes away or reduces in a specific context. In Ayurveda, substances or practices are often referred to in terms of their capacity to alleviate disease or imbalance in the body's systems. Their classification aids in effective treatment recommendations.

39) Indian:
Indian refers to the rich cultural heritage and traditional knowledge stemming from the Indian subcontinent, including Ayurveda. This ancient medical system, developed in India, reflects the country’s unique approach to health and wellness, rooted in natural healing practices and a holistic understanding of the human body.

40) Filling (Filled):
Filled often denotes the presence of specific qualities or substances within a context. In Ayurveda, 'filled' can refer to the essential attributes of medicinal products or formulations, emphasizing harmony and the necessity of balance within the treatment to achieve optimal health outcomes.

41) Kapha:
Kapha is one of the three doshas in Ayurveda, representing earth and water elements. It governs stability, structure, and fluid balance in the body. An increase in Kapha can lead to conditions like obesity and respiratory issues, while its balanced state promotes vitality and health.

42) Nasya (Nashya):
Nasya refers to a nasal therapy in Ayurveda, where herbal oils or powders are administered through the nostrils. It is used for various conditions related to the head, like sinusitis, headaches, and respiratory issues. Nasya forms an essential part of Ayurvedic detoxification practices and promotes overall wellness.

43) Delhi:
Delhi, the capital city of India, is culturally significant and known for its rich historical contributions to Ayurveda, ancient sciences, and medicinal practices. The city serves as a hub for traditional and modern healthcare systems, promoting the integration of Ayurvedic principles into contemporary health practices.

44) Hindi (Himdi):
Hindi is an Indo-Aryan language spoken in India, widely used in communication. In the context of Ayurveda and traditional medicine, Hindi enables a broader understanding and access to ancient texts and practices among practitioners and the public, facilitating the preservation of Ayurvedic knowledge and education.

45) Katu:
Katu translates to bitter in Sanskrit and describes the taste of certain medicinal herbs. In Ayurveda, the bitter taste is associated with stimulating digestion, enhancing metabolism, and purging toxins. The identification of katu herbs helps practitioners create balanced formulations targeting specific health issues.

46) Vati:
Vati refers to a type of Ayurvedic tablet or pill prepared by compressing herbal powders. These formulations provide a convenient and potent means of administering medicines. Vati is often designed for easy consumption, improving patient compliance in adherence to treatment regimens.

47) Devi:
Devi refers to the feminine aspect of divinity in Hinduism and is often invoked in traditional practices, including Ayurveda. The reverence for goddess figures embodies the holistic approach of Ayurveda, where the balance of energy and spiritual awareness is integral to achieving overall health and well-being.

48) Agnivesha (Agni-vesha, Agnivesa):
Agnivesha was an ancient Ayurvedic sage and author of the Agnivesha Samhita, which forms a part of the Charaka Samhita. His contributions significantly shaped Ayurvedic literature and practices, particularly in understanding herbal medicines and their applications in treating various health conditions.

49) Knowledge:
Knowledge in Ayurveda encompasses the understanding of medicinal herbs, dosha balancing, lifestyle practices, and holistic health. It is derived from ancient texts, empirical observations, and continuous learning. Preserving and transmitting this knowledge is critical for effectively applying Ayurvedic principles in modern healthcare.

50) Narayana (Nara-ayana, Nara-yana):
Narayana is a revered figure in Hindu mythology, often associated with divine wisdom and healing. In the context of Ayurveda, the concept of Narayana may symbolize the integration of spirituality and health, emphasizing the importance of holistic approaches to well-being that align with cosmic principles.

51) Sthavara:
Sthavara refers to stationary or immobile entities, typically referring to plants and herbs in Ayurvedic texts. The classification emphasizes the role of plant-based medicines in treatments. Sthavara visha denotes poisons derived from such plants, underscoring their significant therapeutic potentials when properly utilized.

52) Samhita:
Samhita refers to ancient compilations of texts that serve as foundational scriptures in Ayurveda. These texts contain essential knowledge on medicinal formulations, treatment methodologies, and health guidelines, providing practitioners with historical insights and practical approaches for holistic health care.

53) Ardraka:
Ardraka refers to ginger in Ayurveda, recognized for its medicinal properties. It is celebrated for its digestive, anti-inflammatory, and warming qualities. Ardraka is often used in formulations to enhance digestion, relieve nausea, and support overall health, illustrating the importance of culinary herbs in traditional medicine.

54) Bhavana (Bha-vana):
Bhavana refers to the specific process of stirring, mixing, or enhancing herbal substances in Ayurveda. This technique enriches the medicinal properties of herbal formulations, often by adding liquids or heat to potentiate their effects, illustrating the level of care and detail integral to Ayurvedic practices.

55) Trikatu (Tri-katu):
Trikatu refers to an herbal formulation combining three pungent substances: black pepper, long pepper, and ginger. It is a popular remedy in Ayurveda known for its digestive and metabolic benefits. Trikatu is often employed to enhance the effectiveness of other medicinal compounds in formulations.

56) Gandaka (Gamdaka):
Gandaka, or sulfur, is widely used in Ayurveda for its purifying properties. Often added to formulations, it is believed to detoxify the body and aid in skin health. Proper preparation is crucial to mitigate its inherent toxicity while harnessing its therapeutic potential in various treatments.

57) Hingula (Himgula):
Hingula refers to orpiment, a form of arsenic, which is carefully utilized in traditional Ayurvedic practices. Its inclusion in formulations is done meticulously due to its toxic nature. Despite its potential dangers, hingula is considered beneficial in certain contexts when prepared correctly.

58) Burning (Burn, Burned, Burnt):
In Ayurvedic context, burning sensations can indicate various conditions or reactions to substances. For instance, certain poisons or irritants may cause burning sensations in the gastrointestinal tract. Understanding such experiences is vital for diagnosis and treatment pathways to address underlying health issues effectively.

59) Shukla (Sukla):
Shukla means white or bright in Sanskrit. In Ayurveda, this term is often associated with clarity and purity, especially regarding herbal preparations. The use of untainted and purified components in formulations reinforces the holistic emphasis on maintaining integrity and quality in Ayurvedic medicine formulations.

60) Kerala:
Kerala is a southwestern state in India known for its rich tradition in Ayurveda and herbal medicine. The state has become a hub for Ayurvedic practices, attracting both practitioners and patients. Kerala's lush biodiversity provides a wide range of medicinal plants crucial for traditional practice.

61) Castor:
Castor refers to the castor bean plant, which is known for its oil and toxic seeds. While its oil has medicinal applications in Ayurveda, the seeds are highly toxic and require careful processing to ensure safety. This highlights the critical importance of purification in using potentially harmful plants.

62) Nature:
Nature in the Ayurvedic context represents the natural world, including flora and fauna essential for maintaining health. Ayurveda emphasizes harmonizing with natural forces, employing the therapeutic properties of plants while fostering a deeper connection with the environment for holistic well-being.

63) Ushna (Usna):
Usna indicates heat or hotness in Ayurvedic terminology. It describes the qualities of certain herbs or treatments aimed at stimulating metabolic functions and assisting digestion. Recognizing usna properties plays a crucial role in tailoring treatments according to the patient's needs.

64) Pandu (Pamdu, Pamde):
Pandu refers to a yellowish or pale complexion, often associated with conditions like anemia. In Ayurveda, it represents a state of imbalance requiring attention to diet, herbs, and treatments that can replenish blood and restore vitality, highlighting the system's holistic approach to health.

65) Shotha (Sotha):
Sotha generally refers to swelling or edema in Ayurveda. It often signifies an imbalance of doshas, particularly Kapha. Effective treatments for sotha may involve diuretics, detoxifying herbs, and lifestyle recommendations aimed at restoring the body's equilibrium and alleviating the underlying causes.

66) Snuhi:
Snuhi, or the euphorbia plant, is known for its sap used in Ayurvedic medicine. Its applications include treating constipation and various ailments. However, due to its potent effects, careful preparation and dosage are vital for ensuring safe therapeutic use.

67) Water:
Water is vital in Ayurveda for hydration and detoxification. It is frequently used as a vehicle for administering medicines (anupana) and is integral to various healing practices. Proper hydration supports bodily functions and enhances overall health, illustrating its importance in daily wellness routines.

68) Shala (Sala):
Sala refers to a place or area in Sanskrit. It may denote the setting for Ayurvedic practices or healing environments. The significance of the sala in the context of health emphasizes the environment's role in enhancing therapeutic processes and patient recovery.

69) Hair:
Hairs in Ayurveda are connected to individual health status and vitality. Treatments addressing hair health often incorporate topical oils, herbal mixes, and dietary regulations aimed at promoting growth and nourishment, illustrating the interconnectedness of overall health and physical appearance.

70) Milk:
Milk is revered in Ayurveda for its nourishing properties and is often used as a base in various treatments. It enhances the potency of medicinal formulations while providing essential nutrients, demonstrating the core Ayurvedic principle of combining different substances to maximize health benefits.

71) Sthavaravisha (Sthavaravisa, Sthavara-visha):
Sthavara-visha indicates poisons derived from plant sources, categorized based on their toxicity levels. Recognizing sthavara-visha is critical within the Ayurvedic framework, as it highlights the dual nature of many plants that can both harm and heal based on their preparation and usage.

72) Kalpasthana (Kalpa-sthana):
Kalpasthana refers to the section of Ayurvedic texts focused on formulations and preparation methods of medicines. It serves as a foundational guide for practitioners to understand how to prepare effective remedies and the importance of formulation consistency in Ayurvedic practices.

73) Kriyakaumudi (Kriya-kaumudi):
Kriyakaumudi is an Ayurvedic text that elaborates on various therapeutic concepts and practices. It contains numerous methodologies for purification (shodhana) and other critical processes, aiding practitioners in traditional medicine applications, especially regarding toxic plants and their safe usage.

74) Bhallataka:
Bhallataka, or Semicarpus anacardium, is a toxic plant used in Ayurveda. It requires careful preparation to transform its toxic properties into beneficial forms. This highlights Ayurveda’s emphasis on purification processes to ensure safety and efficacy in using potentially harmful herbal substances.

75) Vatsanabha (Vatsa-nabha):
Vatsanabha, or Aconitum, is another toxic plant used in Ayurveda. Proper processing through shodhana is essential for its application in medicine. This reflects the broader Ayurvedic principles surrounding toxic medications and the necessity of transformation to safer medicinal forms.

[Note: The above list is limited to 75. Total glossary definitions available: 294]

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Shodhana, Ayurveda, Visha, Upavisha, Croton tiglium, Medicinal plant, Purification processes, Pharmacological properties, Antidote, Phytochemistry, Clinical Practice, Agadtantra, Botanical Description, Therapeutic dosage, Toxic symptoms, Medico-legal importance, Fatal Dose, Therapeutic measure, Side effect.

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