Novel ayurvedic pulling oil with potent antiviral activity
Journal name: World Journal of Pharmaceutical Research
Original article title: Novel ayurvedic pulling oil with potent antiviral activity
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Original source:
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Amit Sirdesai, Naveen Sharma, Prasun Bandyopadhyay, Ranjan Mitra and Kavita Nagar
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Novel ayurvedic pulling oil with potent antiviral activity
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr20224-23571
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Summary of article contents:
Introduction
The study focuses on the development and evaluation of a novel Ayurvedic pulling oil mouthwash, specifically Dabur Pulling Oil Mouthwash, for its antiviral efficacy against Herpes Simplex Virus Type-1 (HSV-1). HSV-1 is known to cause oral infections characterized by painful cold sores and can be particularly severe in immunocompromised patients. While standard treatments include pharmaceutical antivirals such as acyclovir, repeated usage can lead to drug-resistant virus strains. This research aims to explore natural, herb-based alternatives that could minimize the risks associated with conventional medications.
Antiviral Efficacy of Dabur Pulling Oil Mouthwash
The study reveals significant findings regarding the antiviral properties of Dabur Pulling Oil Mouthwash. It demonstrated a 3.00 Log reduction in HSV-1 virus after a contact time of just 5 minutes at a 0.1% (v/v) concentration, effectively reducing 99.9% of the enveloped virus compared to untreated controls. This highlights the potential for herbal mouthwash formulations to serve as effective therapeutic options for managing HSV-1 infections without contributing to drug resistance.
Importance of Herbal Ingredients in Oil Pulling
The composition of Dabur Pulling Oil Mouthwash includes a unique blend of various medicinal oils. Notable ingredients like sesame oil, coconut oil, clove oil, and peppermint oil are known for their antioxidant, antibacterial, and antiviral properties. Each of these herbal components plays a role in enhancing the mouthwash's efficacy, demonstrating the holistic approach of Ayurveda in treating viral infections. For instance, coconut oil's lauric acid is acknowledged for its antiviral capabilities against enveloped viruses, which includes HSV-1.
Methodological Framework for Testing
The methodological approach of the study involved assessing cytotoxicity through the MTT assay on Vero cells to ensure the safety of the mouthwash. The test substance was evaluated in terms of its effectiveness against the virus through a virucidal activity assay using a standardized viral titer. This rigorous testing demonstrates the scientific basis for the claims made about the mouthwash’s efficacy, ensuring it delivers both safe and effective oral care treatment.
Conclusion
In conclusion, the research presents promising evidence that Dabur Pulling Oil Mouthwash is an effective herbal alternative for treating HSV-1 infections. With its demonstrated antiviral activity and formulation based on Ayurvedic principles, the mouthwash offers a potential avenue for enhancing oral care while addressing the modern challenge of antiviral resistance. The findings urge further exploration and validation of herbal remedies, not only in the context of HSV-1 but also as a sustainable approach in holistic medicine.
FAQ section (important questions/answers):
What is the primary focus of this research study?
The study evaluates the antiviral efficacy of Dabur Pulling Oil Mouthwash against Herpes Simplex Virus Type-1 (HSV-1), offering a natural alternative to traditional antiviral treatments.
How does Dabur Pulling Oil Mouthwash work against HSV-1?
The mouthwash generates antioxidants that disrupt the structure of the HSV-1 virus, inhibiting its ability to bind and penetrate Vero cells, thereby reducing viral load.
What are the main ingredients in Dabur Pulling Oil Mouthwash?
Key ingredients include sesame oil, coconut oil, clove oil, cinnamon oil, peppermint oil, thyme oil, and tulsi oil, all known for their medicinal properties.
What were the results of the antiviral activity testing?
At a 0.1% concentration after 5 minutes, Dabur Pulling Oil Mouthwash exhibited a 3.00 log reduction against HSV-1, indicating a 99.9% reduction of the virus compared to untreated controls.
What is the relevance of Ayurveda in this study?
This research underscores Ayurveda's potential by creating a herbal mouthwash as a natural alternative for managing oral herpes, reinforcing traditional practices with modern scientific validation.
What is the significance of using natural alternatives like this mouthwash?
Natural alternatives like Dabur Pulling Oil Mouthwash pose less risk of developing drug-resistant viruses compared to conventional treatments, promoting safer, more sustainable oral health practices.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Novel ayurvedic pulling oil with potent antiviral activity”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Viru:
The term 'Viru' likely refers to 'virus,' which is central to the study presented. It highlights the relevance of viral infections, particularly Herpes Simplex Virus (HSV-1) in the context of oral health and the effectiveness of natural remedies like Dabur Pulling Oil Mouthwash in combatting viral pathogens and enhancing oral hygiene.
2) Substance:
In the context of the study, 'substance' pertains to the Dabur Pulling Oil Mouthwash evaluated for its antiviral properties against HSV-1. This term emphasizes the formulation of the mouthwash, which is derived from various natural oils and herbs, showcasing an alternative approach to conventional antiviral treatments.
3) Activity:
The term 'activity' relates to the effectiveness of the Dabur Pulling Oil Mouthwash against HSV-1. It demonstrates the product's virucidal properties, emphasizing how it can reduce the viral load substantially, thus showcasing the significance of herbal remedies and their biological efficacy in treating viral infections.
4) India:
India is the origin of Ayurvedic medicine, which forms the foundational approach of the study. The research highlights how traditional Indian herbal knowledge is being integrated into modern scientific studies, focusing on developing natural alternatives to combat viral diseases prevalent in the population.
5) Sharman (Sarma, Sharma, Sarman):
Sharma refers to one of the authors involved in the research. This name symbolizes the collaborative effort of researchers committed to exploring the significance of herbal medicine and its applications in providing safe and effective alternatives to conventional treatments for viral infections.
6) Study (Studying):
The term 'study' indicates the research conducted to evaluate the efficacy of Dabur Pulling Oil Mouthwash against HSV-1. It points to the systematic investigation, including methodology, results, and conclusions, validating the potential of herbal alternatives in addressing oral viral infections.
7) Ayurveda (Ayus-veda):
Ayurveda is a traditional Indian system of medicine that utilizes herbs and natural substances for health benefits. The study incorporates Ayurvedic principles, showcasing the relevance of ancient wisdom and natural therapies in modern medicine, particularly in combating viral infections like HSV-1.
8) Medium:
In this context, 'medium' refers to the culture medium used for growing Vero cells in the laboratory. It highlights the importance of proper laboratory conditions for conducting experiments that assess the effects of the dabur pulling oil mouthwash on HSV-1 infections.
9) Table:
The term 'table' refers to the organized data representation in the study that summarizes findings from various assays. Tables are crucial for conveying results clearly, allowing readers to quickly grasp the effectiveness and cytotoxicity associated with the Dabur Pulling Oil Mouthwash's antiviral activity.
10) Oil:
In the context of the research, 'oils' pertain to the essential oils derived from various medicinal plants used in the formulation of Dabur Pulling Oil Mouthwash. These oils are central to the study's premise, contributing to the mouthwash's antibacterial and antiviral properties.
11) Disease:
Diseases highlight the health issues targeted by the research, specifically oral viral infections like HSV-1. This term frames the urgency for effective treatment options, guiding the exploration and validation of herbal remedies in the realm of healthcare and disease management.
12) Coconut (Cocoanut):
Coconut refers to one of the key ingredients in the formulation of Dabur Pulling Oil Mouthwash. Its oil, comprising medium-chain fatty acids, is known for its antiviral properties, validating its inclusion as a holistic component in the study aimed at treating HSV-1.
13) Antibiotic (Antibacterial):
Antibacterial refers to the potential of certain components within the Dabur Pulling Oil Mouthwash, which not only aims to combat viral infections but also targets bacterial pathogens. This term illustrates the broader application of the product in improving oral health by limiting microbial presence.
14) Cinnamon:
Cinnamon, one of the oils included in the mouthwash, is renowned for its antiviral, antibacterial, and antifungal properties. Its inclusion in the study enhances the understanding of how various traditional herbs work together to achieve beneficial health effects, particularly in oral hygiene.
15) Drug:
Drugs signify conventional pharmaceutical agents that are often used for treating viral infections. Their mention highlights the comparison between standard medications and herbal alternatives, showcasing the ongoing search for effective, safer remedies.
16) Tulsi:
Tulsi, recognized for its medicinal properties, is another key ingredient within the mouthwash formulation. Its inclusion exemplifies the study's adherence to Ayurvedic traditions by using holistic, plant-derived components known for improving health and combating infections.
17) Line:
Line refers to the cell line used in the study, specifically Vero cells. This term highlights the laboratory aspect of the research, emphasizing the use of specialized cell cultures to test the antiviral efficacy of the mouthwash in controlled conditions.
18) Observation:
Observations refer to the results and findings documented throughout the research process. This term signifies the importance of collecting and analyzing data to draw conclusions about the efficacy of Dabur Pulling Oil Mouthwash in virus neutralization.
19) Gandusa (Gandusha, Gamdusa, Gamdusha):
Gandusha is an Ayurvedic term for the practice of holding oil in the mouth, similar to ‘oil pulling,’ which is the method evaluated in the study. This traditional practice reflects the integration of Ayurvedic principles in modern healthcare, showcasing the historical significance of oral wellness.
20) Medicine:
The term 'medicine' in this context denotes the broader field that incorporates this study, specifically focusing on natural and alternative medicine. It indicates the ongoing exploration of effective treatment modalities, especially those arising from traditional systems like Ayurveda, in combating diseases.
21) Kavala:
Kavala refers to the Ayurvedic practice of swishing oil in the mouth, similar to oil pulling. The term emphasizes the cultural roots of this study, advocating for the use of traditional Ayurvedic methods combined with modern science in promoting oral health.
22) Family:
Family pertains to the classification of medicinal plants used in the formulation, highlighting their biological and chemical relationships. In a broader sense, it reflects the interconnectedness of various herbal components and their collective contribution to the mouthwash's efficacy.
23) Pune:
Pune is notable as the location of the National Centre for Cell Sciences, which provided the Vero cells used in the study. The term underscores the geographical context of the research and highlights the contributions of regional institutions in advancing scientific studies in India.
24) Tree:
Trees indicate the natural origins of many medicinal plants. Their significance in the study emphasizes the reliance on sustainable plant resources for formulating health products and highlights the ecological value of preserving biodiversity.
25) Life:
Life refers to the biological significance of the research in enhancing health and well-being. The study underscores the role of natural therapies in improving lives, particularly for individuals afflicted with viral infections, thus validating the relevance of alternative treatments.
26) Ocimum sanctum:
Ocimum sanctum, commonly known as Tulsi, is a revered medicinal plant in Ayurveda. Its inclusion in the study represents the foundation of traditional herbal medicine and signifies the potential of nature-derived substances in combating infections and promoting health.
27) Cocos nucifera:
Cocos nucifera refers to the coconut plant, which provides coconut oil known for its antimicrobial properties. Its mention in the research highlights the role of plant-derived compounds in creating effective herbal remedies, showcasing their benefits in oral care.
28) Discussion:
Discussion constitutes the section of the research where findings are interpreted, compared with existing literature, and implications are drawn. It highlights the significance of the study's results in understanding herbal alternatives for treating viral infections.
29) Developing:
Developing signifies the ongoing process of creating new therapeutic solutions, emphasizing the need for continuous research in finding alternatives to conventional drugs. It reflects the commitment to advancing natural remedies like the Dabur Pulling Oil Mouthwash in viral disease management.
30) Toxicity:
Toxicity refers to the assessment of harmful effects of the test substance on Vero cells within the study. It plays a crucial role in understanding the safety profile of the herbal mouthwash, ensuring that it is effective without causing adverse effects.
31) Science (Scientific):
Science signifies the methodical approach taken in the study, focusing on empirical evidence and rational analysis in evaluating the antiseptic and antiviral properties of the mouthwash, reinforcing the reliability and credibility of the findings.
32) Visarpa:
Visarpa is an Ayurvedic term that can be correlated with viral infections, especially in traditional contexts. Its relevance in the study illustrates the connection between ancient medical practices and contemporary research in treating viral diseases.
33) Species:
Species relates to the various plants utilized in the formulation of the mouthwash. Acknowledging the diversity of plant species supports the study's intent to explore the natural world's potential in creating effective antiviral remedies.
34) Hygiene (Hygienic):
Hygiene underlines the importance of maintaining oral health through preventive measures. This term contextualizes the study within the broader framework of oral care, emphasizing the relevance of integrating natural remedies into daily hygiene practices.
35) Ranjan (Ramjan):
Ranjan is mentioned as one of the authors involved in the research, highlighting the collaborative effort in evaluating herbal formulations. The inclusion of multiple experts reflects diverse insights contributing to a comprehensive understanding of the subject matter.
36) Cancer:
Cancer signifies a broader context of research within which antiviral treatments may play a role, emphasizing the importance of understanding the potential interactions and effects of natural remedies beyond just viral infections.
37) Marble:
Marble in this context refers to the use of natural extracts, possibly linked to the historical or traditional uses of medicinal herbs. Its mention reflects the extensive applications of plant derivatives across various domains, including cosmetics and health.
38) Powder:
Powder may imply the transformation of natural ingredients into forms suitable for therapeutic use. It emphasizes the versatility of herbal components, such as using powdered forms for formulations, enhancing their applicability in various health products.
39) Indian:
Indian highlights the cultural and geographical context of the study, underlining the rich heritage of Ayurvedic practices and the reliance on native plants for developing health solutions, serving as a foundation for the research into herbal medicine.
40) Mitra:
Mitra signifies another contributor to the study, emphasizing collaboration in research, which brings together diverse expertise to validate the findings on the efficacy of the Dabur Pulling Oil Mouthwash.
41) Water:
Water is often mentioned in the context of suspensions or solutions in laboratory settings. Its role is essential in preparing the mouthwash or during experiments, emphasizing the importance of solvents in scientific studies for biological evaluations.
42) Fight:
Fight is relevant in the context of combating viral infections, underscoring the primary goal of the study—to establish a natural, effective solution against HSV-1. It signifies the intent behind research efforts aiming for better health outcomes.
43) Nakar:
Nagar refers to the authors' affiliations, specifically pointing to the institution where they conducted their research. The mention of geographical affiliations roots the study within a specific context in India’s healthcare and research landscape.
44) Wall:
Wall may refer to the structural barriers in cellular contexts, especially in discussing the mechanisms through which the mouthwash interacts with viral particles. It highlights the scientific discourse around cellular mechanisms and interaction with natural compounds.
45) Pain:
Pain indicates the symptoms often associated with viral infections, particularly oral herpes. It underscores the importance of developing effective treatments that alleviate discomfort and improve quality of life for individuals suffering from such conditions.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Novel ayurvedic pulling oil with potent antiviral activity’. Further sources in the context of Science might help you critically compare this page with similair documents:
Sesame oil, Medicinal herb, Coconut oil, Herbal remedies, Oral hygiene, Oil pulling, Active ingredient, Antiviral activity, Vero cells, Clove oil, Natural alternative, Viral shedding, Pharmaceutical agent.