Review of Achyranthes aspera Linn. with a focus on Nighantu.

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Journal name: World Journal of Pharmaceutical Research
Original article title: An in depth review of achyranthes aspera linn. with special reference to nighantu
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Author:

Sumita Ghosh and Avik Pal


World Journal of Pharmaceutical Research:

(An ISO 9001:2015 Certified International Journal)

Full text available for: An in depth review of achyranthes aspera linn. with special reference to nighantu

Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research

Doi: 10.20959/wjpr20226-24130

Copyright (license): WJPR: All rights reserved


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Summary of article contents:

Introduction

Herbal medicine has been an integral part of human healthcare since ancient times, particularly in India, where traditional herbal remedies are deeply rooted in cultural practices. A well-known medicinal plant, Achyranthes aspera Linn., commonly referred to as Apamarga, has been embraced for its diverse therapeutic properties. Found widely across India, this plant is characterized by its erect growth and prickly flowers. Various parts of Achyranthes aspera, such as its roots, seeds, and leaves, are rich in chemical compounds that provide numerous medicinal benefits, including diuretic, antimicrobial, and hypoglycemic effects.

Chemical Constituents and Their Health Benefits

The therapeutic efficacy of Achyranthes aspera can be attributed to its rich assortment of secondary metabolites. The roots contain compounds such as ecdysterone, oleanolic acid, and glycosides, while its seeds are known to house saponins. These bioactive constituents are believed to exert protective effects against various health conditions. Research indicates that these compounds play pivotal roles in treating ailments ranging from digestive disorders to skin diseases. For instance, the plant has shown significant anti-inflammatory activities and is often utilized in the management of conditions like abdominal pain and skin disorders.

Pharmacological Activities

Numerous pharmacological studies have highlighted the diverse health benefits of Achyranthes aspera. Among its many applications, the plant exhibits diuretic properties, promoting increased urine output and electrolyte excretion. This diuretic effect has been tested through various animal models, revealing a marked increase in urine volume and the excretion of key ions, confirming the plant's traditional use in treating urinary tract disorders. Furthermore, studies have demonstrated its antimicrobial activity against several bacterial strains, supporting its use as a natural remedy against infections.

Applications in Traditional Medicine

In traditional Ayurvedic practices, Achyranthes aspera is utilized for its extensive therapeutic properties, including its roles in mitigating the doshas of kapha and vata. The plant is incorporated into various formulations for treating ailments such as fever, digestive issues, and skin problems. For example, its application as a paste for bites from snakes or scorpions highlights its relevance in traditional medicinal protocols. Additionally, the leaves and roots of the plant are prized for their ability to enhance digestive health, detoxify the body, and support overall wellness.

Conclusion

In conclusion, Achyranthes aspera Linn. represents a noteworthy example of a plant that bridges traditional herbal medicine and contemporary pharmacological research. Its rich chemical composition imbues it with various therapeutic properties, making it a valuable resource in healthcare. As society increasingly seeks natural remedies and holistic approaches to health, the exploration of Achyranthes aspera could pave the way for innovative treatments that honor centuries-old practices while contributing to modern medicine. Further research into its benefits and mechanisms of action will be vital in integrating this herb into contemporary therapeutic practices.

FAQ section (important questions/answers):

What is Achyranthes aspera and its common names?

Achyranthes aspera, commonly known as Prickly Chaff Flower, has various names including Apamarga in Sanskrit, Chirchita in Hindi, and Mayuraka in Tamil, among others.

What are the key medicinal properties of Achyranthes aspera?

Achyranthes aspera possesses diuretic, antimicrobial, hypoglycaemic, spasmolytic, and vasodilator activities, making it effective for treating various health conditions.

Which parts of the plant are used in herbal medicine?

The roots, leaves, and the whole plant of Achyranthes aspera are utilized in traditional medicine for various therapeutic applications.

What are the chemical constituents found in Achyranthes aspera?

Key constituents include ecdysone, ecdysterone, oleanolic acid, saponins, and alkaloids such as achyranthine and betaine, contributing to its medicinal effects.

What traditional uses does Achyranthes aspera have in Ayurveda?

In Ayurveda, it is used for conditions like abdominal pain, skin disorders, and urinary tract issues, often in conjunction with other herbs.

What pharmacological activities has Achyranthes aspera been studied for?

Research on Achyranthes aspera shows activities such as anti-inflammatory, antipyretic, antioxidant, and anti-obesity effects, confirming its beneficial properties.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Review of Achyranthes aspera Linn. with a focus on Nighantu.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Nighantu (Nighamtu):
Nighantus are specific Ayurvedic texts that systematically catalog medicinal plants and their properties, similar to Nighantu. They serve as reference guides for practitioners, providing detailed information on the various synonyms, classifications, and uses of herbs, facilitating their effective application in therapy.

2) Activity:
Activity in this context typically refers to the biological effects exhibited by specific compounds in medicinal plants. Understanding the various activities of herbs enables medicinal practitioners to effectively utilize plants like Achyranthes aspera for various therapeutic interventions, from antimicrobial to anti-inflammatory effects.

3) Apamarga:
Apamarga is the name for Achyranthes aspera, a herb commonly found in India known for its diverse medicinal properties. Recognized for its applications in Ayurveda, Apamarga has been used for treating various ailments, reflecting its importance in traditional herbal medicine and its rich historical context.

4) Varga:
Varga refers to classifications or groups within Ayurvedic texts that categorize medicinal plants based on their shared properties or therapeutic effects. Understanding these classifications aids practitioners in selecting appropriate herbs for treatment, ensuring that therapies align with individual health needs and conditions.

5) Rasa (Rasha):
Rasa denotes the taste or flavor profile of a herb in Ayurveda, serving as a vital indication of its therapeutic properties. The identification of Rasa helps inform how a plant can potentially affect bodily doshas, guiding practitioners in creating effective and personalized treatment plans.

6) Katu:
Katu translates to 'pungent' in Ayurveda, describing one of the six primary tastes (Rasa). This taste is important as it influences digestive functions and can aid in the management of conditions like congestion and digestive discomfort, particularly within the context of utilizing Apamarga.

7) Samhita:
Samhitas, plural of Samhita, denotes collections of Ayurvedic texts that compile knowledge on herbs, treatments, and medical principles. These texts form the backbone of Ayurvedic medicine, providing comprehensive insights into the therapeutic uses of plants like Achyranthes aspera across different health contexts.

8) Virya:
Virya signifies the potency or action of a herb in Ayurveda, specifically its thermogenic property. This concept helps determine how a plant acts within the body, enhancing its therapeutic potential, especially for conditions requiring heating or cooling properties, guiding practitioners' decisions.

9) Guna:
Gunas encompass the inherent qualities of substances, aiding practitioners in evaluating herbs based on their therapeutic actions. Recognizing Gunas enhances the scope of treatment approaches, ensuring the alignment of herb characteristics with patient needs and conditions.

10) Antibiotic (Antibacterial):
Antibiotic refers to substances that destroy or inhibit the growth of microorganisms. The context of herb-derived antibiotics illustrates the advancing recognition of traditional plants like Achyranthes aspera in contemporary medical practices as effective alternatives to synthetic drugs.

11) Medicine:
Medicines encompass a broad range of substances used to treat diseases. The significance of herbal medicines like those derived from Achyranthes aspera lies in their long-standing cultural usage, highlighting the holistic approaches and rich traditions in herbal healing practices.

12) Ushna (Usna):
Ushna translates to 'hot' in the context of Ayurvedic terminology, often describing the thermogenic quality of certain herbs. This property indicates how a plant can stimulate bodily functions, beneficial for conditions that require warming effects, such as digestive issues or respiratory ailments.

13) Mayuraka:
Mayuraka is a Sanskrit synonym for Achyranthes aspera, indicating its recognized identity in Ayurvedic literature. Such synonyms are crucial for understanding the plant's significance in traditional practices and its various therapeutic qualities, underscoring its longstanding use in herbal medicine.

14) Tikshna (Tiksna):
Tikshna denotes a sharp or penetrating quality within Ayurvedic herbology, indicating its vigorous action on the body. This quality suggests the capacity of certain plants, such as Apamarga, to effectively stimulate digestion and enhance metabolic processes, making it valuable in therapeutic contexts.

15) Aureus:
Aureus, as referenced in the context of antibacterial studies, often refers to Staphylococcus aureus, a common bacterium that can cause infections. The effectiveness of herbal extracts against Aureus highlights the importance of natural remedies in combating resistant bacterial strains.

16) Tikta:
Tikta translates to 'bitter' in Ayurvedic terminology. This taste is significant as it helps balance bodily doshas, often enhancing digestive health. Tikta is associated with cleansing actions and can aid liver function, offering therapeutic benefits from plants such as Apamarga.

17) India:
India is the geographic origin of Achyranthes aspera and is renowned for its rich tradition of herbal medicine and Ayurvedic practices. The diverse climatic and ecological conditions of India support the growth of many medicinal plants, making it a center for herbal therapy.

18) Ulcer:
Ulcer signifies a break or sore in a bodily surface, often requiring medicinal intervention. The mention of ulcer treatment in the context of Achyranthes aspera underscores its importance in traditional medicine for promoting gastrointestinal health and providing relief from ulcerative conditions.

19) Table:
Table refers to organized data presented succinctly for easy reference and comparison. In this document, tables cataloging various classifications, synonyms, and properties of Apamarga facilitate quick access to information essential for practitioners utilizing this plant in herbal medicine.

20) Dhanvantarinighantu (Dhanvantari-nighantu):
Dhanvantari-nighantu is a specific Ayurvedic text that categorizes medicinal plants and their uses. Its significance lies in preserving traditional knowledge, incorporating a wide range of herbs and their properties, including Achyranthes aspera, guiding practitioners in selecting appropriate remedies.

21) Kharamanjari (Khara-manjari, Kharamamjari):
Kharamanjari is another term for Achyranthes aspera, emphasizing its various synonyms in Ayurvedic texts. The use of diverse names reflects the plant's multifaceted applications and historical significance in treating various ailments within the framework of traditional herbal medicine.

22) Dhanvantari (Dhanvamtari):
Dhanvantari is a revered figure in Ayurvedic tradition, often termed as the god of medicine. References to Dhanvantari underscore the spiritual and holistic foundations of Ayurveda, highlighting how plants like Apamarga relate to the larger context of healing practices.

23) Mahakashaya (Mahakasaya, Maha-kashaya):
Mahakasaya refers to a category or group in Ayurvedic texts that includes potent herbs used for specific treatments. Understanding Mahakasaya helps practitioners identify effective remedies, underlying the importance of categorizing herbal substances based on their therapeutic properties and effectiveness in practice.

24) Durgraha (Dur-graha):
Durgraha is a term referring to a species of medicinal plant with specific properties. Within the context of Ayurvedic texts, understanding plants categorized as Durgraha allows practitioners to correlate their uses and therapeutic actions with particular ailments or health conditions, enhancing treatment effectiveness.

25) Marga:
Marga refers to a pathway or channel in Ayurveda, symbolizing both physical and metaphysical routes toward health. The application of Marga enhances the understanding of how medicines traverse these channels to exert therapeutic effects on the body through medicinal plants.

26) Roga:
Roga translates to 'disease' or 'disorder' in Ayurveda. Identifying specific Rogas helps practitioners determine the appropriate herbal treatments and remedies required for restoring balance in the body, emphasizing the holistic approach taken in traditional healing practices.

27) Gaya (Gayà):
Gaya is a city in India known for its significance in various cultural and medicinal practices. It serves as a reference point for the application of plants such as Apamarga within the herbal medicinal traditions specific to its geographic and cultural context.

28) Gana:
Gana refers to a classification group of medicinal substances in Ayurveda based on shared properties and therapeutic functions. Recognizing Gana aids in the correct identification and application of herbs according to their respective therapeutic actions, enriching Ayurvedic practice.

29) Drug:
A drug is a pharmacologically active substance used for treating diseases or alleviating symptoms. The discussion of drugs derived from plants such as Achyranthes aspera emphasizes the importance of herbal sources in developing effective treatments within modern and traditional medical systems.

30) Pharmacological:
Pharmacological refers to the study of drugs and their effect on living organisms. Investigating the pharmacological properties of plants like Achyranthes aspera can lead to the discovery of new treatments and deepen understanding of how traditional remedies function on a biochemical level.

31) Kaphavata (Kapha-vata):
Kapha-vata are two of the three doshas in Ayurveda, representing different elemental and functional qualities in the body. The mention of these doshas is key in tailoring herbal treatments, ensuring that remedies such as Apamarga address specific imbalances for improved health outcomes.

32) Flavonoid:
Flavonoid, as a specific type of flavonoid compound, is crucial for understanding the chemical makeup of medicinal plants. Research into flavonoids contributes to exploring how these compounds affect various biological processes, enhancing the efficacy of herbal therapies.

33) Krimighna (Krmighna, Krimi-ghna):
Krimighna is a term referring to substances with antiparasitic properties within Ayurvedic practice. Identifying Krimighna plants allows practitioners to address specific parasitic infections effectively, illustrating how herbs like Achyranthes aspera play a role in holistic health and disease management.

34) Shikhari (Sikhari):
Sikhari is another synonym for Achyranthes aspera, enhancing the understanding of this plant's utilization in Ayurvedic traditions. The diverse nomenclature accentuates the significance and versatility of the herb across various texts and its essential role in herbal medicine.

35) Disease:
Disease indicates a disruption of normal bodily functions or processes. The focus on disease within herbal medicine underscores the importance of identifying specific conditions in order to tailor treatments effectively with plants like Achyranthes, enhancing overall health.

36) Kaphaja:
Kaphaja refers to conditions arising from imbalances in the Kapha dosha in Ayurveda. Understanding Kaphaja ailments is essential for practitioners in selecting appropriate herbal treatments, illustrating the targeted approach achieved through traditional medicine based on individual constitutions.

37) Mutrala:
Mutrala describes a property referring to diuretic effects in Ayurveda. This term emphasizes the importance of herbs that promote urination and help in treating conditions related to fluid retention or urinary tract disorders, using plants like Achyranthes aspera.

38) Ashmari (Asmari):
Ashmari refers to stones or gravel formations in the urinary tract or gallbladder in Ayurvedic texts. Identifying plants effective against Ashmari, like Apamarga, is crucial for managing conditions related to urinary health, showcasing the plant's significance in traditional therapies.

39) Markati:
Markati is an alternative name for Achyranthes aspera, reflecting its recognition in classical texts. This further showcases how various synonyms contribute to a deeper understanding of the plant's adaptive uses in different herbal formulations within Ayurveda.

40) Vikara:
Vikara is a term that indicates a transformation or change resulting in disease or disorder. Understanding Vikara enables practitioners to connect imbalances in the body with potential treatments, effectively utilizing herbs for restoration and balance in health.

41) Aghata:
Aghata refers to the physical presence or nature of a plant, often used to describe its utility in treatment. Incorporating Aghata in medicinal discussions supports the overall understanding of plant characteristics that govern their use in therapeutic practices.

42) Vedana:
Vedana signifies 'pain' or 'sensation' in Ayurveda. The consideration of Vedana is key in addressing chronic and acute conditions, allowing practitioners to explore herbal solutions which alleviate discomfort, improve quality of life, and enhance therapeutic outcomes.

43) Ruksha (Ruksa):
Ruksha translates to 'dry' in Ayurvedic terminology, often describing a property of certain herbs. Recognizing Ruksha helps in assessing a plant's potential effects on bodily tissues and fluids, thus guiding its applications in treating diseases with excessive moisture or fluids.

44) Vipaka:
Vipaka denotes the post-digestive effect of a substance, indicating how its essence impacts the body after assimilation. This concept is crucial for Ayurvedic practitioners in determining how to integrate a herb, based on its therapeutic actions post-consumption.

45) Kapha:
Kapha is one of the three doshas in Ayurveda, representing earth and water elements. Managing Kapha imbalances is essential in Ayurveda, and understanding its characteristics aids practitioners in selecting appropriate herbal treatments to restore health balance.

46) Laghu:
Laghu translates to 'light' in the Ayurvedic context, indicating properties of certain herbs that promote ease and digestion. The concept of Laghu is significant for creating effective treatment plans in addressing conditions like heaviness and lethargy within the body.

47) Rakta:
Rakta implies the blood component in Ayurvedic terms. Recognizing ailments related to Rakta is important for practitioners, as they can utilize specific herbs that enhance blood health, promoting overall physical well-being and vitality in treatment protocols.

48) Taila (Thaila):
Taila means 'oil' in Ayurvedic terminology, which plays a critical role in preparation for herbal formulations. It highlights the significance of combining herbs with oils for enhanced therapeutic applications and absorption, showcasing the holistic nature of Ayurveda.

49) Priya:
Priya means 'beloved' or 'dear' in Sanskrit, often used in the context of naming certain plants or remedies in Ayurvedic texts. This term conveys the deep-rooted cultural respect and affection associated with particular herbs and their roles in healing across generations.

50) Water:
Water is a fundamental component in Ayurveda, serving as a medium for herbal infusions, decoctions, and preparations. The significance of water in the therapeutic process emphasizes the importance of hydration and its role in supporting overall health and well-being.

51) Blood:
Blood is a vital substance in the context of health and disease. Understanding blood's composition and function is crucial in traditional medicine, helping practitioners identify conditions requiring intervention with specific herbs to restore balance in the circulatory system.

52) Hair:
Hair in the context of medicinal texts can also refer to aspects of plant growth, offering insights into specific species. Noting these characteristics adds depth in identifying useful herbs for treatment while emphasizing the detailed observation fundamental in herbal medicine.

53) Hara:
Hara signifies 'remover' often used to describe plants that eliminate imbalances or toxins within the body. Recognizing the healing qualities of Hara helps practitioners assess the potential effects of herbs like Apamarga in delivering therapeutic benefits.

54) Vati:
Vati refers to a medicinal preparation in the form of pills or tablets in Ayurveda. The development of Vati from plants incorporates herbal actions, enhancing their usability and providing practitioners convenient methods for delivering traditional remedies effectively.

55) Vata:
Vata refers to one of the three doshas in Ayurveda associated with air and ether elements. Understanding Vata's characteristics is crucial for tailoring treatments that mitigate its imbalances, employing remedies derived from plants such as Achyranthes aspera to restore balance.

56) Sara (Shara):
Sara translates to 'essence' or 'fluid' within Ayurvedic texts, implying the essential quality of a plant. Recognizing Sara helps in assessing a herb's internal potency and effectiveness in managing health conditions, contributing to tailored treatment strategies.

57) Diet:
Diet plays a pivotal role in Ayurvedic medicine, emphasizing the significance of nourishing foods and herbal inclusions for optimal health. Understanding dietary choices is essential for practitioners in developing holistic treatment plans that align with individual health needs.

58) Sushruta-samhita (Susruta-samhita):
Susruta-samhita, a significant text in Ayurveda, provides in-depth knowledge on surgical procedures and herbal remedies. Its comprehensive guidance on treatments places it at the forefront of Ayurvedic medicine, emphasizing the interconnection of herbs with surgical and healing practices.

59) Markatapippali (Markata-pippali):
Markatapippali refers to a specific collection or term related to medicinal plants, sometimes relating to species of plants with known health benefits. This highlights the importance of understanding various terms and names used to classify plants in herbal medicine.

60) Agnimukharasa (Agnimukha-rasa):
Agnimukha-rasa refers to a category of medicinal preparations in Ayurveda known for their warming properties. Recognizing such categories helps practitioners align treatments more effectively with patient needs based on their elemental properties and desired therapeutic outcomes.

61) Panktikantaka (Pankti-kantaka):
Panktikantaka denotes a specific categorization of plants within Ayurvedic literature, emphasizing their particular therapeutic properties. Understanding such designations aids practitioners in choosing the right herbs for addressing specific health conditions in a personalized manner.

62) Mahashankha (Mahasankha, Maha-shankha, Mahashamkha):
Mahashankha is a name associated with certain Ayurvedic formulations or plants known for their potency. This term reflects the importance of recognizing traditional remedies that contribute to healing practices within Ayurvedic contexts.

63) Malakantaka (Mala-kantaka):
Malakantaka signifies a particular plant or term in the context of Ayurvedic texts, indicating its medicinal applications. Understanding these terms allows practitioners to better categorize and utilize various herbs in treatment, ensuring effective management of health conditions.

64) Measurement:
Measurement refers to the quantification of dosage or application of herbal preparations. Accurate measurement is crucial in Ayurveda for ensuring therapeutic efficacy, providing clear guidance on how much of a particular herb or formulation should be used.

65) Dravyaguna (Dravya-guna):
Dravyaguna is the branch of Ayurveda that studies the properties of drugs and substances, acknowledging their therapeutic actions. This comprehensive knowledge allows practitioners to understand how various herbs interact within the body and their potential effects on health and wellness.

66) Kushthaghna (Kusthaghna):
Kusthaghna relates to medicinal substances known for their effectiveness against skin diseases. Identifying Kusthaghna plants is essential for treating various dermatological conditions, showcasing Apamarga's application within Ayurvedic practices.

67) Shaikharika (Saikharika):
Saikharika is a traditional name associated with specific herbs in Ayurvedic texts that indicates its recognized properties. The resonance of these traditional names emphasizes the cultural and historical significance of herbs in providing holistic therapeutic benefits.

68) Parakpushpi (Paranc-pushpi, Parakpuspi, Paranpuspi):
Parakpuspi refers to a term in herbal medicine highlighting certain plants used for their therapeutic effects. This term emphasizes the importance of recognizing various plants and their specific applications in treating health conditions effectively.

69) Krimiroga (Krmiroga, Krimi-roga):
Krimi-roga describes infections caused by parasites and worms. Understanding Krimi-roga aids practitioners in selecting appropriate herbal treatments, ensuring that remedies like Achyranthes aspera effectively manage and alleviate such conditions.

70) Apamargadi:
Apamargadi is often related to formulations or preparations inclusive of Achyranthes aspera. This term aids in recognizing the specific applications and benefits derived from the plant's use in traditional remedies and its role in health restoration.

71) Vishtambhin (Vistambhin, Vishtambhi, Vistambhi):
Vishtambhi refers to a condition characterized by constipation or difficulty in bowel movements. Recognizing this term emphasizes the importance of utilizing herbs that can alleviate such conditions, guiding practitioners in prescribing effective laxative remedies.

72) Kaphapitta (Kapha-pitta):
Kaphapitta refers to a health condition arising from the imbalance of both Kapha and Pitta doshas. Understanding Kaphapitta enables practitioners to select remedies that address this dual imbalance, promoting overall harmony through holistic treatment approaches.

73) Snake-bite:
Snake-bite signifies a medical emergency requiring immediate treatment. The mention of Achyranthes aspera's use in treating snake bites underscores its significance in traditional herbal medicine for averting life-threatening conditions and promoting recovery.

74) Substance:
Substance refers to the materials or components that underlie the physical characteristics and therapeutic efficacy of medicinal herbs. Understanding these substances is critical for practitioners to extract and apply the healing properties effectively.

75) Gandamala (Ganda-mala):
Gandamala relates to conditions of nasal obstruction or respiratory issues within Ayurvedic texts. Identifying plants effective against Gandamala emphasizes the role of herbs like Achyranthes aspera in alleviating respiratory ailments and promoting clear breathing.

[Note: The above list is limited to 75. Total glossary definitions available: 145]

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