Phytochemical screening and antimicrobial activity in Kalyan's plants
Journal name: World Journal of Pharmaceutical Research
Original article title: Screening of phytochemicals & determination of antioxidants content and antimicrobial activity in medicinal plants of kalyan
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
This page presents a generated summary with additional references; See source (below) for actual content.
Original source:
This page is merely a summary which is automatically generated hence you should visit the source to read the original article which includes the author, publication date, notes and references.
Santhini S. Nair, Pooja Jagasia, Malay Shah, Shweta Patil and Komal Pareek
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Screening of phytochemicals & determination of antioxidants content and antimicrobial activity in medicinal plants of kalyan
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr20226-24201
Download the PDF file of the original publication
Summary of article contents:
1) Introduction
Medicinal plants have been recognized for their rich composition of phytochemicals that play a vital role in enhancing human health and treating various ailments. This study aimed to investigate the phytochemical constituents and antioxidant properties of several medicinal plants available in Kalyan, India, specifically focusing on Tulsi leaves and stem, Ajwain, and Cloves. The investigation included qualitative phytochemical screening and quantitative determinations of bioactive compounds, including flavonoids, ascorbic acid, and phenolic compounds. The antimicrobial activities of the extracts against selected microbial strains were also assessed.
2) Phytochemical Composition and Antioxidant Properties
The phytochemical analysis revealed the presence of a broad range of bioactive compounds in the examined plants. Notable constituents included flavonoids, which were detected in all extracts, while other phytochemicals such as alkaloids, glycosides, and phenolic compounds exhibited varied presence across the different plants. Quantitative measurements showed that Tulsi stem possessed the highest total flavonoid content (77.746 mg/g), while Ajwain showed the maximum ascorbic acid content at 49.94 mg/g. This underscores the plants' potential as natural sources of antioxidants, which are crucial for mitigating oxidative stress and associated health problems.
3) Antimicrobial Activity Assessment
The antimicrobial properties of the plant extracts were evaluated using agar cup diffusion methods against various pathogenic microorganisms. While aqueous extracts demonstrated no significant antimicrobial activity, the ethanolic extracts exhibited considerable antibacterial effects against gram-positive and gram-negative bacteria, as well as antifungal activity against Candida albicans. Clove extract displayed the strongest antibacterial activity against Staphylococcus aureus, highlighting its potential as a natural antimicrobial agent. These findings suggest that the selected medicinal plants could serve as valuable alternatives to conventional antimicrobial treatment, especially in the context of rising antibiotic resistance.
4) Traditional Medicine and Phytochemicals
The utilization of phytochemicals in traditional systems of medicine, particularly in Ayurveda, emphasizes the historical significance of plants in healthcare practices. The study emphasizes that India's rich biodiversity has long been a source of medicinal solutions, with a significant percentage of modern drugs derived from plant sources. The plants examined not only possess therapeutic properties but also contribute to wider health practices, including cosmetics and food supplements. The validation of these traditional remedies through scientific analysis fosters an understanding of their potential role in contemporary medicine.
5) Conclusion
The study highlights the significant phytochemical diversity and potential health benefits of Tulsi, Ajwain, and Cloves. It indicates that these plants are not only rich in antioxidants but also possess essential antimicrobial properties, underscoring their importance in traditional and modern medicine. The findings support the exploration and further investigation of these plants for their therapeutic potentials, advocating for their continued integration into health care practices. The research fosters a greater appreciation for herbal remedies and points to a pathway for developing new herbal medications based on traditional knowledge.
FAQ section (important questions/answers):
What are the main medicinal plants studied in this research?
The main medicinal plants studied are Tulsi, Ajwain, and Cloves, which were evaluated for their phytochemical content and antimicrobial activity.
What phytochemicals were identified in the plant extracts?
The phytochemicals identified include flavonoids, ascorbic acid, total phenols, alkaloids, and tannins, demonstrating diverse bioactive properties.
Which plant extract showed the highest total flavonoid content?
The Tulsi stem extract exhibited the highest total flavonoid content, measured at 77.746 mg/g as Quercetin equivalents.
What was the antimicrobial activity of the plant extracts?
Ethanol extracts showed significant antibacterial activity, particularly Clove extract against Staphylococcus aureus and Tulsi stem extract against Candida albicans.
How was the total phenolic content measured?
Total phenolic content was measured using the Folin-Ciocalteu phenol reagent method, with Ajwain showing the highest content.
What conclusions were drawn from this research?
The study concludes that these medicinal plants contain beneficial phytochemicals with potential antimicrobial and antioxidant properties, supporting their traditional medicinal use.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Phytochemical screening and antimicrobial activity in Kalyan's plants”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Tulsi:
Tulsi, also known as Holy Basil, is an aromatic medicinal plant revered in Ayurvedic medicine for its numerous health benefits. Its extracts contain bioactive compounds that possess antimicrobial, antioxidant, and anti-inflammatory properties, making it an essential subject of research in phytochemical studies aimed at utilizing natural remedies for ailments.
2) Phytochemical:
Phytochemicals encompass various bioactive compounds derived from plants with health-promoting properties. Their screening and quantification in medicinal plants is vital for discovering new therapeutic agents, as they can enhance physiological functions, protect against diseases, and contribute to overall well-being, forming the basis of natural healthcare approaches.
3) Flavonoid:
Flavonoids, as a subgroup of phytochemicals, play a significant role in the medicinal properties of plants. Their antioxidant and antibacterial capabilities make them a focus of research for developing natural remedies to combat diseases and improving health through diet, highlighting their importance in plant-based medicinal studies.
4) Activity:
In the context of this study, 'activity' refers to the biological effects exhibited by the phytochemicals isolated from medicinal plants. This includes antimicrobial, antioxidant, and various therapeutic effects, which are crucial for validating the use of such plants in traditional medicine and their potential applications in modern healthcare.
5) Antibiotic (Antibacterial):
Antibiotics are substances used to combat bacterial infections. Given the rise of antibiotic resistance, researching plant-derived compounds for their antibiotic properties is becoming increasingly important, supporting the exploration of natural alternatives to traditional antibiotics in modern medicine.
6) India:
India is rich in biodiversity and traditional medicinal practices, particularly concerning plants that are used in Ayurvedic and other traditional medicine systems. The study of medicinal plants in India, such as Tulsi, Ajwain, and Clove, emphasizes the country's significance in phytochemical research and the development of natural pharmaceuticals.
7) Water:
Water is a universal solvent and is often used in extracting bioactive compounds from plants through aqueous methods. Understanding the role of water in extracting phytochemicals is crucial for standardizing and optimizing extraction processes, which can affect the yield and efficacy of the medicinal properties of plant extracts.
8) Study (Studying):
The study is an investigative process aimed at understanding the phytochemical composition and biological activities of selected medicinal plants. Research in this area helps to validate traditional claims about the health benefits of these plants and provides scientific evidence supporting their use in natural medicine.
9) Oil:
Oils extracted from plants, particularly essential oils, contain a variety of bioactive phytochemicals contributing to their therapeutic properties. The study of oils, often rich in phenolic compounds like those found in Cloves and Ajwain, emphasizes their importance in antimicrobial and antioxidant activities, key to their medicinal applications.
10) Medicine:
Medicines represent the broader category of substances used for healing or alleviating health issues. The study emphasizes the importance of understanding plant-derived medicines in the context of traditional practices and their relevance in contemporary therapeutic approaches, revealing the depth of natural remedies.
11) Disease:
Diseases are specific pathological conditions that disrupt normal bodily functions. Studying phytochemicals' potential to combat diseases emphasizes the importance of exploring natural remedies to develop effective treatments, especially in light of the increasing resistance to conventional antibiotics.
12) Science (Scientific):
Science is the systematic study of structure and behavior of the physical and natural world through observation and experimentation. Phytochemical research falls within this purview, applying scientific methods to validate the properties and efficacy of traditional medicinal plants for potential health benefits.
13) Rich (Rch):
Rich indicates a high abundance of a certain element, such as bioactive compounds in medicinal plants. The richness of phytochemicals in plants like Tulsi emphasizes their value in developing natural health products and understanding the diverse benefits they offer to human health.
14) Drug:
Drugs denote chemicals or substances used for medical purposes. The research aims to validate the potential of phytochemicals in medicinal plants as a source of new drugs, exploring their efficacy and safety in treating diseases and improving healthcare outcomes.
15) Maharashtra (Maharastra, Maha-rashtra):
Maharashtra is a state in India known for its diverse flora and traditional knowledge of medicinal plants. The study of phytochemicals within this geographical context emphasizes local biodiversity and the need to explore indigenous practices that could lead to significant health discoveries.
16) Education:
Education in the context of this study relates to the dissemination of knowledge regarding the efficacy of medicinal plants and their phytochemical constituents. It underscores the importance of scientific research in bridging traditional knowledge and modern science for healthcare advancements.
17) Commerce:
Commerce pertains to the activity of buying and selling, which, when applied to the context of medicinal plants, emphasizes the potential for developing and commercializing herbal medicines. The study highlights revenue generation through the utilization of plant-based resources in pharmacy and healthcare sectors.
18) Aureus:
Aureus commonly refers to 'Staphylococcus aureus,' a pathogenic bacteria studied in relation to antimicrobial resistance. The relevance in this study emphasizes evaluating plant extracts against such pathogens to gauge their effectiveness and support the development of herbal alternatives to traditional antibiotics.
19) Medium:
Medium indicates the nutrient-rich environment employed in microbiological studies for cultivating microorganisms. The choice of medium affects the growth of test cultures, influencing the evaluation of antimicrobial activities of plant extracts, which is vital for determining their effectiveness in treating infections.
20) Table:
Table refers to structured data representation within the study, showcasing quantitative results of phytochemical analysis and their quality. Tables facilitate the interpretation of data, allowing readers to comprehend the comparative effectiveness of different plant extracts and their biological activities.
21) Performance:
Performance in this study context refers to the effectiveness of plant extracts in exhibiting biological activities, including antimicrobial effects. Measuring performance allows for evaluating the potential of different phytochemical constituents, justifying their use in alternative medicine practices and ensuring their practical application.
22) Surrounding:
Surrounding indicates the environment or context in which the research takes place, highlighting the importance of environmental factors in the growth and efficacy of medicinal plants. Understanding these factors contributes to maximizing the extraction and bioactivity of phytochemicals for therapeutic uses.
23) Discussion:
Discussion encompasses the analysis and interpretation of experimental findings, providing insights into the relevance of results in the broader context of medicinal plant research. It draws connections between phytochemical content, biological activity, and potential therapeutic applications, contributing to future research directions.
24) Ayurveda (Ayus-veda):
Ayurveda is an ancient system of medicine originating in India, emphasizing holistic treatment and the use of plant-based remedies. The study connects the traditional use of medicinal plants to contemporary scientific validation, bridging ancient wisdom with modern healthcare practices and substance efficacy.
25) Species:
Species refers to specific types of organisms, in this context, highlighting the wide variety of plants explored for their medicinal properties. Understanding plant species increases knowledge about their unique phytochemical profiles and potential applications in healthcare and pharmacology.
26) Mishra (Misra):
Mishra is mentioned as an author associated with studies on the antimicrobial properties of medicinal plants. The reference to their work underscores its relevance and supports the validity of the current research findings regarding the health benefits of phytochemical-rich plant extracts.
27) Animal:
Animals, as living organisms distinct from plants, are often used in research to test the effects of phytochemicals found in plant extracts. Understanding how these compounds affect animal health provides insights into potential benefits or risks in human applications, bridging the gap between species.
28) Glass:
Glass in this context pertains to laboratory equipment made from Pyrex or Borosil, used for accurate measurements and ensuring the integrity of experiments. High-quality glassware is crucial for reliability in scientific measurements, promoting the precision of experimental outcomes in phytochemical analysis.
29) Food:
Food signifies substances consumed for sustenance, where certain phytochemicals from medicinal plants also enhance dietary health. Researching plant extracts' nutritional properties helps inform dietary recommendations and develop functional foods that may offer health benefits beyond basic nutrition.
30) Life:
Life refers to the condition that distinguishes organisms from inorganic matter, encompassing biological processes. Research into phytochemicals from plants aims to understand their role in enhancing life quality and longevity through natural therapeutic avenues, emphasizing their impact on health and well-being.
31) Human body:
The human body refers to the physical structure of human beings, which is responsive to various compounds. Understanding how phytochemicals interact with human physiology is essential for developing effective therapeutic agents derived from plants, promising advancements in natural healthcare solutions.
32) Pharmacological:
Pharmacological pertains to the study of how drugs interact with biological systems. Researching phytochemicals' pharmacological properties is essential for identifying new therapeutic agents, bridging the gap between traditional medicine and modern pharmacology in combating various health conditions.
33) Measurement:
Measurement denotes the process of quantitatively determining the properties or concentrations of substances in experiments. In phytochemical research, precise measurements ensure reproducibility and validity of results, which is essential for establishing reliable data to support therapeutic applications.
34) Depression:
Depression refers to a mood disorder characterized by persistent sadness and loss of interest. Understanding how natural compounds, such as those derived from medicinal plants, can influence mental health is an emerging field of study, suggesting potential therapeutic avenues for alleviating depressive symptoms.
35) Knowledge:
Knowledge encompasses understanding gained through study and experience. In the context of medicinal plants, acquiring knowledge about their phytochemical constituents and health benefits informs effective practices in healthcare, enabling traditional wisdom to contribute to modern therapeutic strategies.
36) Fragrance:
Fragrance refers to pleasant and distinctive smells derived from plants. Many medicinal plants have aromatic properties that contribute not only to their appeal but also to their therapeutic benefits, enhancing user experience with botanical medicines and encouraging broader acceptance in wellness practices.
37) Himalaya (Hima-alaya):
Himalaya, similar to Himalayas, points to the significant topographical and ecological region. This geographical focus indicates the richness of medicinal plants in the area, highlighting the potential for discovering new biologically important phytochemicals that could lead to novel therapeutic agents.
38) Bleeding:
Bleeding refers to the loss of blood, which can be pathological. Certain phytochemicals are studied for their potential to promote wound healing and clotting, with implications for developing treatments that address bleeding disorders and improve recovery outcomes in patients.
39) Quality:
Quality denotes the standard of something as measured against other things of a similar kind. In studies assessing medicinal plants, quality control ensures the consistency and efficacy of extracts, contributing to the reliability of their therapeutic use in medicine.
40) Hygiene (Hygienic):
Hygiene refers to practices designed to maintain health and prevent disease, emphasizing the importance of cleanliness. The overlap with medicinal plants underscores how certain plant extracts can contribute to maintaining hygiene through antibacterial properties, making them relevant in public health discussions.
41) Siddha:
Siddha refers to an ancient system of medicine practiced in South India, emphasizing the holistic healing approach. The relevance of Siddha in the study highlights the importance of integrating traditional forms of medicine with modern pharmacological research focused on plant-derived remedies.
42) Wisdom:
Wisdom reflects the accumulated knowledge and experience in traditional practices, particularly in medicine. The study ties ancient wisdom to modern research, encouraging the exploration of traditional methods for uncovering new therapeutic compounds found in medicinal plants.
43) Sharman (Sarma, Sarman, Sharma):
Sharma is referenced as an author, indicating contributions to the existing body of knowledge regarding medicinal research. His findings are relevant and inform the current study, contributing to a collaborative understanding of phytochemicals in plant extracts.
44) Indian:
Indian pertains to the cultural and geographical context regarding the use of medicinal plants. The study emphasizes India's rich heritage in traditional medicine, particularly Ayurveda, showcasing the relevance of indigenous knowledge in current phytochemical research efforts.
45) Patil:
Patil is named as an author contributing to the research. By referencing the collaboration of various authors, including Patil, the study highlights the multifaceted approach to investigating medicinal plant properties and the importance of collective expertise in scientific exploration.
46) Pooja:
Pooja refers to one of the contributing authors of the study. The inclusion of collaborative efforts from different researchers illustrates the collaborative nature of scientific investigation, particularly in the realm of traditional medicine and phytochemical research.
47) Sugar:
Sugar, in this context, refers to carbohydrates that are present in various biological systems, including plants. Understanding carbohydrate profiles in medicinal plants is essential for elucidating their energy-providing capacities and role in metabolic processes, contributing to the overall health benefits extracted from these plants.
48) Fever:
Fever is a common symptom of infection or illness, indicating the body's response to pathogens. The investigation of phytochemical properties in plants aims to discover natural remedies that can alleviate fever symptoms and offer alternative treatments for such common health issues.
49) Wine:
Wine is noted for containing beneficial phytochemicals such as flavonoids, which exhibit antioxidant properties. In the study, the relevance of wine underscores the growing interest in researching plant-based beverages for their health-promoting effects and potential as alternative therapeutic agents.
50) Sah:
Shah is mentioned as one of the authors, contributing to the overall research on medicinal plants. The collaboration among different experts, including Shah, emphasizes the collective effort required to understand and validate the health benefits of phytochemical-rich plant extracts.
51) Ghat (Gham):
Ghat may refer to a specific geographical area significant for biodiversity. Regions labeled as Ghats in India are known for unique biodiversity, often producing a variety of medicinal plants that are crucial to phytochemical research and the development of new health remedies.
52) Wall:
Wall can refer to the structural boundary of a cell. Understanding the impact of phytochemicals on cellular walls could offer insights into their mechanisms of action against pathogens and underscore their potential in developing new antimicrobial treatments.
53) Cup:
Cups relate to the experimental format used in microbiological analysis for evaluating antimicrobial activity. They serve as containers to introduce test samples and are essential for measuring the effectiveness of various plant extracts against specific microorganisms, providing vital data in the study.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Phytochemical screening and antimicrobial activity in Kalyan's plants’. Further sources in the context of Science might help you critically compare this page with similair documents:
Medicinal plant, Flavonoid, Phytochemical, Tulsi leaves, Chronic disease, Traditional medicine, Ayurvedic medicine, Antimicrobial activity, Zone of inhibition, Ethanolic extract, Total flavonoid content, Ascorbic acid, Microbiological analysis, Quantitative determination, Standard antibiotic, Phenolic compound, Antioxidant system.