Efficacy of triphala mashi anjana in pterygium post-excision.

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Journal name: World Journal of Pharmaceutical Research
Original article title: To study the efficacy of triphala mashi anjana in pterygium w.r.t. arma after excision
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Author:

Dr. Harshal R. Deshmukh


World Journal of Pharmaceutical Research:

(An ISO 9001:2015 Certified International Journal)

Full text available for: To study the efficacy of triphala mashi anjana in pterygium w.r.t. arma after excision

Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research

Doi: 10.20959/wjpr20227-24366

Copyright (license): WJPR: All rights reserved


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Summary of article contents:

Introduction

Pterygium, characterized by the abnormal growth of conjunctival tissue on the cornea, poses significant challenges in modern ophthalmology, especially due to environmental factors such as pollution and increased exposure to sunlight. These factors have heightened the incidence of pterygium, making effective treatment vital. The study, led by Dr. Harshal R. Deshmukh, aims to evaluate the efficacy of Triphala Mashi Anjana—a traditional Ayurvedic formulation—post-surgical excision of pterygium, specifically concerning changes in the condition known in Ayurveda as Arma. By comparing outcomes between a trial group receiving the formulation and a control group treated with standard surgical procedures and antibiotics, the research intends to establish the formulation's clinical benefits.

Role of Traditional Ayurvedic Treatment

The unique aspect of this study lies in the integration of Ayurvedic concepts with modern medical practices. In Ayurveda, Arma is understood as a condition classified among sandhigata rogas, which necessitates surgical intervention when vision is compromised. The Ayurvedic philosophy emphasizes a holistic approach, considering the balance of doshas (body energies: Vata, Pitta, and Kapha) when treating conditions like pterygium. Triphala Mashi Anjana, being composed of three fruits—Haritaki, Bibhitaki, and Amalaki—along with specific salts, has properties that align with the goal of pacifying doshas, enhancing vision, and promoting healing post-surgery. This integration paves the way for alternatives that may prevent recurrence and improve visual outcomes more effectively than standard care alone.

Effectiveness of Triphala Mashi Anjana

The study found that the application of Triphala Mashi Anjana significantly improved symptoms among those treated post-excision. The findings indicated a notable reduction in foreign body sensation, local redness, and corneal astigmatism in the experimental group compared to the control group. Quantitative metrics exemplified that recipients of the Ayurvedic formulation experienced faster symptomatic relief and better visual acuity outcomes. Statistical analyses supported these observations, with the calculated t-values demonstrating significant effectiveness of the Ayurvedic treatment concerning common pterygium symptoms, reinforcing the potential of Triphala Mashi Anjana in enhancing post-operative care.

Comparative Analysis of Treatment Groups

A comparative evaluation of the treatment groups revealed compelling outcomes favoring the addition of Triphala Mashi Anjana. In the experimental group consisting of 30 patients, 13 were reported cured, and 16 improved, while only 8 patients were cured in the control group of similar size. The faster and more effective mitigation of symptoms in the trial group underscored the therapeutic potential of the formulation, signaling that patients not only benefited from the surgical excision but also from the combined treatment involving an Ayurvedic approach. This suggests that the holistic treatment modality can serve as a suitable adjunct to conventional methods, particularly where visual disturbances and astigmatism are concerned.

Conclusion

The findings of this study encourage further exploration into traditional Ayurvedic treatments within modern medical frameworks. The effectiveness of Triphala Mashi Anjana in managing pterygium post-surgical excision not only highlights its potential as a supportive treatment but also advocates for more expansive research into such integrative practices. Given the observed reduction in symptoms and improved recovery rates compared to standard treatments, Triphala Mashi Anjana could represent a valuable addition to ophthalmic care. Future studies are necessary to fully delineate its benefits, particularly concerning recurrence rates and long-term visual acuity improvements, ensuring patients receive comprehensive, effective, and accessible care for pterygium management.

FAQ section (important questions/answers):

What is the focus of Dr. Harshal R. Deshmukh's study?

The study focuses on the efficacy of Triphala Mashi Anjana in treating pterygium after excision, comparing results between a trial group receiving the formulation and a control group undergoing standard treatment.

What are the objectives of the study?

The objectives include assessing the effect of Triphala Mashi Anjana on pterygium and evaluating clinical changes after excision in relation to the Ayurvedic concept of Arma.

What was the sample size for the study?

The study included 60 patients with pterygium, divided into two groups of 30 each, to compare the efficacy of the treatment methods.

What treatment did the trial group receive?

The trial group was treated with pterygium excision, antibiotic drops, and Triphala Mashi Anjana, which aimed to enhance recovery and reduce symptoms.

How was the effect of treatment evaluated?

The treatment effects were evaluated through subjective symptom assessments and objective measures like visual acuity and corneal astigmatism at various follow-up intervals.

What were the study's conclusions regarding Triphala Mashi Anjana?

The study concluded that the combination of excision, antibiotics, and Triphala Mashi Anjana is effective for pterygium management, showing better outcomes compared to excision alone.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Efficacy of triphala mashi anjana in pterygium post-excision.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Triphala (Tri-phala):
Triphala is a traditional Ayurvedic herbal formulation consisting of three fruits: Haritaki, Bibhitaki, and Amalaki. It is renowned for its myriad health benefits, including digestive health, detoxification, and boosting immunity. In the context of pterygium treatment, it is believed to have properties that improve vision and balance the body's doshas.

2) Masi (Mashi):
Masi refers to a paste or topical application often used in Ayurvedic treatments. In this study, it specifically refers to the formulation of Triphala Mashi Anjana, highlighting the method of application and the benefits derived from its use in managing eye conditions.

3) Arma:
Arma is a term in Ayurveda related to sandhigata rogas, which refers to conditions impacting the joints or bodily structure. In the study, it is correlated with pterygium, emphasizing Ayurvedic perspectives on treating this eye condition through surgical and herbal interventions linked to overall joint health.

4) Study (Studying):
Study refers to a systematic investigation or analysis conducted to discover or clarify facts, particularly in the medical field. In this context, the study explored the efficacy of Triphala Mashi Anjana on patients with pterygium, contributing to the understanding and advancement of treatments in Ayurvedic medicine.

5) Anjana (Amjana):
Anjana denotes a type of eye ointment in Ayurveda, derived from various herbal ingredients and used for treating eye disorders. Triphala Mashi Anjana, the focus of the study, combines the benefits of Triphala with specific therapeutic properties to alleviate symptoms related to pterygium after surgical excision.

6) Table:
In this study, tables are employed to present data clearly and concisely, allowing for straightforward comparison of findings. They summarize the results of treatment effects on various symptoms, aiding in the visual assessment of changes and responses in patients under the study.

7) Antibiotic (Antibacterial):
Antibiotics are crucial in modern medicine for treating bacterial infections. In the context of this study, they were used post-surgery alongside Triphala Mashi Anjana to prevent infections that can arise after pterygium excision, thereby enhancing patient safety and recovery.

8) Ayurveda (Ayus-veda):
Ayurveda is a traditional Indian system of medicine that emphasizes holistic health through balance in body, mind, and spirit. This ancient practice includes various treatments, herbal remedies, and lifestyle recommendations. The study utilizes Ayurvedic concepts and formulations to address modern health issues like pterygium.

9) Dosha (Dosa):
In Ayurveda, doshas are the three fundamental bodily energies believed to govern physical and mental processes. They include Vata, Pitta, and Kapha. Each person has a unique combination of doshas influencing their health, and treatments aim to restore balance among them, especially in managing diseases like pterygium.

10) Sign:
Sign refers to an indication or characteristic symptom of a condition observed during clinical assessment. In the context of this study, signs of pterygium involve symptoms like redness, foreign body sensation, and visual disturbances, reflecting the condition's impact on ocular health and guiding treatment decisions.

11) Drug:
Drugs in this context refer to medicinal substances used for treatment. The study focuses on the herbal components of Triphala Mashi Anjana. Here, the effectiveness of these drugs in treating pterygium and enhancing recovery is evaluated against conventional treatments in clinical trials.

12) Disease:
Diseases encompass a wide range of medical issues requiring treatment. This study focuses on pterygium as one specific disease, examining the effectiveness of a traditional Ayurvedic remedy while offering insights into broader health treatment approaches.

13) Kapha:
Kapha is one of the three doshas in Ayurveda responsible for structure and fluid balance in the body. It embodies qualities like heaviness and stability. An imbalance in Kapha may contribute to ailments such as pterygium, thus treatments aim to restore harmony to mitigate symptoms.

14) Lekhana:
Lekhana, meaning 'scraping' in Ayurveda, refers to a therapeutic action aimed at removing or reducing abnormal tissues or doshas from the body. Triphala's Lekhana properties are highlighted in this study, emphasizing its role in alleviating histopathological changes associated with pterygium post-excision.

15) Nature:
Nature, in an Ayurvedic context, refers to the inherent qualities or characteristics of substances or individuals, influencing health and disease. The study examines the nature of Triphala ingredients and how their specific properties contribute to managing conditions like pterygium effectively.

16) Dushta (Dusta):
Dusta signifies 'impure' or 'corrupted' in Ayuvedic terminology, often used to describe doshas or body tissues that have become deranged. In the context of the study, the term discusses how Dusta mansa dhatu and Dusta kapha dosha contribute to symptoms of pterygium, necessitating therapeutic intervention.

17) Observation:
Observations refer to the detailed monitoring of patient responses during the clinical study, providing data to assess treatment efficacy. Systematic observations allow for informed conclusions about the effectiveness of Triphala Mashi Anjana in managing pterygium post-excision.

18) Chedana:
Chedana refers to the surgical technique in Ayurveda that denotes cutting or excision of abnormal growths or tissues. In this study, it concerns the excision of pterygium alongside the application of Triphala Mashi Anjana, showcasing a combined approach to managing ocular diseases.

19) Bhedana:
Bhedana indicates penetration or breaking down of tissues in Ayurveda. This property is relevant when discussing how the ingredients of Triphala Mashi Anjana may promote healing and mitigate symptoms of pterygium by overcoming physical barriers in the affected ocular tissues.

20) Burning (Burn, Burned, Burnt):
Burning is used descriptively in the context of pterygium, reflecting both an uncomfortable sensation experienced by patients and the inflammation associated with the condition. It signifies the urgency of treatment and highlights the need for interventions that soothe such symptoms.

21) Sadhya:
Sadhya means 'curable' in Ayurveda, referring to diseases that can be treated or eradicated successfully. The study evaluates the effectiveness of Triphala Mashi Anjana in curing symptoms related to pterygium, supporting the notion that certain conditions can be managed within holistic treatment frameworks.

22) Ruksha (Ruksa):
Ruksha translates to 'dry' in Ayurveda and denotes a quality that may help in balancing excessive moisture or secretions in the body. In the context of pterygium treatment, Ruksha properties of Triphala's ingredients may aid in alleviating symptoms tied to excess Kapha dosha.

23) Lavana:
Lavana refers to 'salt' in Ayurvedic terminology, often recognized for its properties of preservation and enhancing flavors. In medicinal contexts, it is used for its detoxifying qualities and is included in formulations like Triphala Mashi Anjana, enriching the therapeutic effects for ocular ailments.

24) Vyadhin (Vyadhi):
Vyadhi translates as 'disease' or 'disorder' in Ayurveda. This term encompasses various health issues, including pterygium, presenting a framework for understanding the pathological changes and guiding effective treatments based on Ayurvedic principles.

25) Karma (Karman):
Karma refers to an action or procedure in Ayurveda, often connected to therapeutic practices. In this study, it relates to the surgical procedures (Shastra karma) for excising pterygium, followed by post-operative treatments like Triphala Mashi Anjana, in addressing the condition efficiently.

26) Laghu:
Laghu means 'light' in an Ayurvedic context, describing substances or treatments that are easy to digest or have a reducing effect on excess weight or heaviness in the body. Triphala Mashi's Laghu properties suggest it may assist in clearing excess doshas post-excision.

27) Ushna (Usna):
Ushna, meaning 'hot', describes the heating properties of certain substances in Ayurveda. In Triphala Mashi Anjana, Ushna attributes are thought to assist in alleviating inflammation and redness associated with pterygium, contributing to the overall effectiveness of the treatment.

28) Male:
Male designates gender in a clinical study context, indicating inclusion criteria. In this study, both male and female participants aged 25-70 were assessed for the efficacy of Triphala Mashi Anjana in managing symptoms of pterygium, providing diverse data on treatment outcomes.

29) Kaphadosha (Kaphadosa, Kapha-dosha):
Kapha-dosha is one of the three Ayurvedic doshas, characterized by earth and water elements. An imbalance in Kapha can lead to conditions like pterygium involving excessive moisture and heaviness. The study highlights therapeutic actions aiming to restore balance in Kapha for effective treatment.

30) Chandrapur:
Chandrapur refers to the location where the study was conducted. Identifying geographic context for clinical research helps in understanding the demographic and environmental factors influencing the prevalence and treatment of conditions like pterygium within specific populations.

31) Haritaki:
Haritaki is one of the three ingredients in Triphala, valued for its numerous health benefits, including digestive health and detoxification. Its inclusion in Triphala Mashi Anjana contributes to treating conditions like pterygium, enhancing the overall therapeutic efficacy of the formulation.

32) Shastra (Sastra):
Shastra refers to the texts and principles in Ayurvedic medicine that guide surgical and therapeutic procedures. The study invokes Shastra principles in discussing surgical methods for pterygium excision, highlighting the intersection of traditional knowledge and contemporary medical practices.

33) Sukshma (Suksma, Shukshma):
Sukshma means 'subtle' in Ayurveda and refers to the fine qualities or textures of substances. This property is relevant in the context of Triphala Mashi Anjana, as its subtle nature allows for effective penetration and action at the micro-level of ocular tissues affected by pterygium.

34) Amalaki:
Amalaki is one of the three fruits comprising Triphala, known for its rich vitamin C content and antioxidant properties. It plays a significant role in promoting ocular health and is included in formulations like Triphala Mashi Anjana aimed at treating diseases affecting the eyes.

35) Kalpana:
Kalpana refers to the preparation or formulation of a medicinal substance in Ayurveda. In this study, it underscores the careful formulation of Triphala Mashi Anjana as a holistic treatment aimed at managing pterygium, reflecting traditional Ayurvedic principles in modern application.

36) Tantra (Tantrism, Tamtra):
Tantra in Ayurveda refers to systems or methodologies applied in healing practices, often encompassing both theoretical and practical aspects of treatments. This term highlights the structured approach taken in Ayurveda, especially in addressing diseases like pterygium utilizing knowledge derived from ancient texts.

37) Pitta:
Pitta is one of the three doshas associated with metabolism, transformation, and digestion. An imbalance in Pitta can lead to inflammatory conditions, including pterygium. The study's approach includes managing Pitta through Triphala Mashi Anjana to address symptoms effectively.

38) Snayu:
Snayu refers to the 'tendons' or connective structures in the body, indicating the broader context of how Ayurvedic principles apply to various bodily systems. The understanding of Snayu can help in correlating symptoms of pterygium with underlying structural health issues.

39) Dhatu:
Dhatu denotes the fundamental biological tissues in Ayurveda, which includes aspects like muscles, blood, and others. Understanding Dhatu is central to diagnosing and treating conditions like pterygium, wherein the health of these tissues can influence symptoms experienced by patients.

40) Roga:
Roga represents 'disease' and is a critical aspect of Ayurvedic diagnostics. Each Roga, such as pterygium being studied here, is evaluated within the framework of doshas, dhatus, and treatment modalities, reflecting the comprehensive approach of Ayurveda in healthcare.

41) Vata:
Vata is one of the three doshas in Ayurveda, associated with motion, dryness, and air. An imbalance in Vata may contribute to various health issues, including pterygium. This study investigates how treatments address Vata imbalances to enhance recovery post-excision.

42) Lamp:
A lamp, used for illumination in clinical settings, can symbolize the importance of clarity in observing symptoms during examinations. It represents the methods like torch and slit lamp used to assess ocular conditions such as pterygium effectively during the study.

43) Salt (Salty):
Salt contributes to the flavor and preservation of food but also serves medicinal purposes in Ayurveda. In the context of Triphala Mashi Anjana, the use of salts enhances therapeutic properties and provides a balanced blend of ingredients, improving overall treatment effectiveness.

44) Pittadosha (Pittadosa, Pitta-dosha):
Pitta-dosha represents one of the three vital energies in Ayurveda linked to heat and metabolism. Understanding Pitta-dosha's role is essential in diagnosing conditions like pterygium, where imbalance may amplify symptoms, emphasizing the need for targeted treatment strategies.

45) Rock salt:
Rock salt, known for its mineral-dense properties, plays a role in food and traditional medicine. In this study's context, rock salt's inclusion in Triphala Mashi Anjana aids the healing process by providing essential minerals and enhancing the formulation's therapeutic effectiveness.

46) Shalakyatantra (Salakyatantra, Shalakya-tantra, Shalakyatamtra):
Shalakya-tantra is an Ayurvedic branch focused on head, eyes, ears, nose, and throat diseases. Referring to this branch in the study underscores the specialized approaches used in treating pterygium, correlating traditional knowledge with surgical and medicinal interventions.

47) Kaphapitta (Kapha-pitta):
Kapha-pitta describes a state where both Kapha and Pitta doshas are simultaneously involved, indicating a complex interplay in a patient's health status. This understanding is critical in managing conditions like pterygium, where a dual approach may enhance treatment efficacy.

48) Vatadosha (Vatadosa, Vata-dosha):
Vata-dosha is one of the three principal doshas that govern motor functions and the nervous system. An imbalance in Vata can contribute to various disorders. This study highlights how managing Vata-dosha is integral to treating conditions like pterygium effectively.

49) Discussion:
Discussion refers to the analytical part of the study where results are examined and interpreted. It plays a vital role in synthesizing findings related to Triphala Mashi Anjana’s efficacy in managing pterygium, allowing for informed conclusions to be drawn about treatment outcomes.

50) Bibhitaka:
Bibhitaka, part of the Triphala formulation, is known for its health benefits including supporting digestive health and detoxification. Its inclusion in Triphala Mashi Anjana enhances the overall treatment effectiveness for conditions like pterygium, demonstrating its valuable role in Ayurvedic formulations.

51) Suffering:
Suffering denotes the experiences of discomfort or distress faced by patients due to diseases like pterygium. The study addresses suffering by exploring a treatment that alleviates symptoms and enhances the quality of life for those affected by the condition.

52) Tridosha (Tri-dosha, Tridosa):
Tridosha represents the three doshas (Vata, Pitta, Kapha) in Ayurveda that define an individual's health and constitution. Understanding the interplay of Tridosha is crucial in evaluating and treating pterygium, as imbalances can lead to various health issues.

53) Shodhana (Sodhana):
Shodhana denotes the process of purification in Ayurveda, aimed at removing toxins and restoring health. The study indicates the importance of Shodhana practices in conjunction with treatments for pterygium, suggesting a holistic approach to managing the disease.

54) Rasayani:
Rasayani refers to rejuvenating and anti-aging components in Ayurveda. Triphala contains Rasayani properties that support overall health and vitality, and its application in pterygium treatment underscores the aim of restoring balance and function in affected areas.

55) Channel:
Channel signifies the pathways for energy and information in the body, relevant in understanding how treatments disseminate and act within the system. In pterygium treatment, it relates to how therapies like Triphala exploit these channels for effective symptom relief.

56) Mandala (Mamdala):
Mandala is traditionally used to represent circles or cycles in various cultures. In this study, it may refer to the encompassing nature of Ayurvedic medicine in diagnosing and treating conditions like pterygium, which affects multiple systems within the body.

57) Pradhan:
Pradhan translates to 'principal' or 'foremost' in Ayurveda, typically designating the primary condition or dosha affecting a patient. Understanding the Pradhan dosha aids in accurately diagnosing and formulating effective treatment plans for pterygium management.

58) Science (Scientific):
Science refers to the systematic study of the structure and behavior of the physical and natural world through observation and experimentation. This study combines scientific approaches with traditional Ayurvedic practices to explore and validate the effects of Triphala Mashi Anjana on pterygium management.

59) Shukla (Sukla):
Shukla means 'white' or 'clear' and often describes qualities associated with purity and health in Ayurveda. It may denote the ideal state in managing conditions like pterygium, where restoring clarity and health to the eye is the primary goal of treatment.

60) Vishad (Visad):
Vishad translates to 'clear' or 'pure' in the context of Ayurveda, denoting a state of health and clarity. This quality relates to the treatment of pterygium where restoring the clarity of the eye is associated with reducing symptoms and enhancing vision.

61) Bahala:
Bahala means 'thick' or 'bulky' and may refer to the appearance of overgrown or excessive tissue seen in conditions like pterygium. Understanding Bahala helps in identifying the need for surgical intervention and the potential benefits of treatments like Triphala Mashi Anjana.

62) Powder:
Powder refers to the form in which many Ayurvedic medicines are prepared, allowing for easier consumption and application. In the case of Triphala Mashi Anjana, powders of the individual herbs are combined to create a potent formulation aimed at healing ocular disorders.

63) Mamsa (Mamsha):
Mamsa translates to 'muscle' or 'flesh' in Ayurveda. It's important when discussing the growths and tissues affected by conditions like pterygium, where abnormal mamsa growth requires careful consideration in treatment approaches that include excision and herbal remedies.

64) Rakta:
Rakta refers to 'blood' in Ayurveda, representing one of the dhatus, or fundamental biological tissues. Understanding its role helps in diagnosing conditions where blood flow may be affected, such as in cases of pterygium, ensuring appropriate therapeutic strategies are applied.

65) India:
India is the geographical context where Ayurveda originated and flourished. Its cultural significance includes rich traditions in herbal medicine and holistic healing practices, bridging the gap between ancient knowledge and modern medical applications, as seen in pterygium research.

66) Blood:
Blood, a vital fluid in the body, represents life and vitality. In Ayurveda, the health and quality of blood (rakta dhatu) can affect overall health and may play a role in diseases like pterygium, influencing treatment decisions and therapeutic strategies.

67) Fainting (Fainted):
Faint describes a dim or weak quality, often referring to visual acuity in the context of pterygium. Patients may experience faint vision due to abnormalities caused by the condition, highlighting the importance of effective treatments aimed at restoring clarity and health.

68) Guna:
Guna stands for quality or attribute, essential in Ayurveda for classifying substances based on their physical and energetic properties. Evaluating the gunas of the herbs in Triphala Mashi Anjana informs about its potential actions and the overall health benefits provided.

69) Rasa (Rasha):
Rasa can denote taste but also refers to the essence of various Ayurvedic herbs and formulations. In this study, the Rasa of the components in Triphala Mashi Anjana influences its effectiveness in treating symptoms of pterygium.

70) Aha (Ahan, Ahar):
Ahar refers to diet or nourishment in Ayurveda and emphasizes the importance of food choices in maintaining health. Nutritional habits impact dosha balance and contribute to treatment outcomes in conditions like pterygium, where diet plays a supportive role in overall care.

71) Diet:
Diet signifies the food consumed, profoundly affecting health in Ayurvedic practice. The study suggests an awareness of dietary aspects while managing health conditions, emphasizing that appropriate Ahar is necessary alongside treatments like Triphala Mashi Anjana for optimal recovery.

Other Science Concepts:

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Discover the significance of concepts within the article: ‘Efficacy of triphala mashi anjana in pterygium post-excision.’. Further sources in the context of Science might help you critically compare this page with similair documents:

Surgical excision, Statistical analysis, Inclusion criteria, Exclusion criteria, Clinical efficacy, Symptomatic improvement, Visual acuity, Visual disturbance, Randomized control trial, Follow-Up Assessment, Pashchat Karma, Tridoshghna, Ayurveda Method, Mashi kalpana.

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