A critical review of ashwagandha (withania somnifera (l.) dunal.)
an ayurvedic health tonic
Journal name: World Journal of Pharmaceutical Research
Original article title: A critical review of ashwagandha (withania somnifera (l.) dunal.)
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Subtitle: an ayurvedic health tonic
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Dr. Shubham Bansal, Dr. Rosy Gupta, Dr. Vishavender Attri and Dr. Minakshi Kaundal
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Full text available for: A critical review of ashwagandha (withania somnifera (l.) dunal.)
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr20229-24953
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Summary of article contents:
Introduction
Ashwagandha (Withania somnifera L. Dunal) is a prominent medicinal herb in Ayurveda, renowned for its rejuvenating properties. Classified as a Rasayana, it is recognized for its strength-enhancing, bulking, and revitalizing effects across major classical Ayurvedic texts known as the Brihatryi. Modern research has begun to validate its effectiveness not just within traditional frameworks but as a health-promoting supplement across various studies, showcasing its potential applications in contemporary health sciences.
Adaptogenic and Anti-Stress Effects
One of Ashwagandha's key attributes is its adaptogenic properties, which help the body manage stress. Research indicates that it functions similarly to Siberian Ginseng and Chinese Ginseng, enhancing the body's resistance to stress through various mechanisms. For example, studies have shown that administering Ashwagandha can significantly increase plasma corticosterone levels and improve immune response in stress-induced conditions. These findings lend credence to its long-standing use in traditional medicine as a natural remedy for stress management and recovery.
Immuno-Modulatory Activity
Another significant area of research involves Ashwagandha's immuno-modulatory effects. The herb has been found to enhance the immune response, making it a potential candidate in vaccine development. An innovative project has led to a vaccine adjuvant extracted from Ashwagandha, underscoring its role in immunity enhancement. This aligns with various classical mentions of the herb in Ayurvedic texts as an immunity booster, suggesting its multifaceted utility in both preventive and therapeutic contexts.
Neuroprotective Effects
Ashwagandha also exhibits promising neuroprotective effects, making it relevant in the context of neurodegenerative disorders such as Alzheimer’s and Parkinson’s diseases. Key active compounds found in Ashwagandha, like glyco-withanolides and withaferin-A, have shown potential in reversing cognitive impairments and protecting neuronal integrity in various experimental models. The herb's ability to promote neurogenesis and reduce oxidative stress encourages its use as a natural supplement for cognitive enhancement and protection against age-related neurological decline.
Conclusion
In summary, Ashwagandha is a revered herb in Ayurveda known for its various health benefits, encompassing areas such as stress management, immune enhancement, and neuroprotection. Modern scientific research supports traditional claims of its efficacy, highlighting its potential as a multi-faceted health tonic. With ongoing investigations into its therapeutic applications, particularly in stress-related disorders and neurodegenerative diseases, Ashwagandha stands out as an invaluable component of both traditional and contemporary health strategies. The integration of this ancient remedy into modern health practices showcases the enduring relevance of Ayurvedic medicine in today’s health landscape.
FAQ section (important questions/answers):
What is Ashwagandha and its traditional use?
Ashwagandha, or Withania somnifera, is an Ayurvedic medicinal herb renowned for its rejuvenating properties and is primarily used as a nervine tonic to treat various ailments as per Ayurvedic texts.
What are the main medicinal properties of Ashwagandha?
Ashwagandha is known for its adaptogenic, anti-stress, immuno-modulatory, anti-inflammatory, and anti-tumor activities, making it beneficial for general health and vitality.
How is Ashwagandha used to improve strength?
Ashwagandha is often taken with milk, ghee, or honey to enhance strength, promote muscle growth, and improve overall physical health, particularly for those suffering from weakness.
What are the potential effects of Ashwagandha on stress?
Research suggests that Ashwagandha effectively reduces stress and anxiety, improving mood and physical performance, similar to other adaptogens like Siberian Ginseng and Chinese Ginseng.
How does Ashwagandha contribute to cognitive health?
As a Medhyarasayana, Ashwagandha promotes intellect and memory, making it useful for children with memory deficits and for elderly individuals experiencing cognitive decline.
What scientific backing supports Ashwagandha's health benefits?
Numerous studies confirm Ashwagandha's health benefits, including anti-stress effects, anti-tumor activity, and support for cognitive function, affirming its status as a valuable herbal remedy.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “A critical review of ashwagandha (withania somnifera (l.) dunal.)”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Ashvagandha (Ashva-gandha, Ashvagamdha, Ashwagandha, Asvagandha):
Ashvagandha is a variation of the name Ashwagandha, often used in various texts and discussions within Ayurveda. It retains the same properties and applications as its primary nomenclature.
2) Powder:
In Ayurvedic medicine, the term 'powder' refers to the ground form of herbs, including Ashwagandha. The powdered form enhances bioavailability, making it easier to consume. It is often mixed with liquids such as milk or water and used in various preparations to maximize therapeutic benefits.
3) Nighantu (Nighamtu):
Nighantus are compilations of medicinal plants within Ayurvedic literature. These texts play a crucial role in classifying herbs like Ashwagandha, detailing their uses and enhancing practitioners' understanding.
4) Activity:
The term 'activity' in the context of medicinal herbs refers to the biological effects or therapeutic actions that a substance exerts on the body. In Ashwagandha's case, its adaptogenic, anti-inflammatory, and cognitive-enhancing activities are key aspects studied in both traditional and modern scientific research.
5) Milk:
Milk is often used in Ayurveda as a carrier for herbs like Ashwagandha. When combined with herbal powders, it enhances digestion and absorption, providing nourishment and promoting various health benefits. It is often prescribed as part of formulations to improve strength and vitality.
6) Varga:
In Ayurvedic texts, 'varga' refers to categories or classes of medicinal plants based on their shared properties and effects. Understanding these classifications aids practitioners in selecting the appropriate herbs for specific conditions, ensuring effective treatment strategies in Ayurvedic practice.
7) Ghi (Ghee):
Ghee, or clarified butter, is a significant component in Ayurvedic medicine, often used as a base for herbal preparations. It enhances the absorption of herbal constituents, provides nourishment, and is believed to possess healing properties. Ghee is also used for cooking and as a medicine.
8) Rasayana (Rasa-ayana):
Rasayanas are mental and physical rejuvenators in Ayurveda that promote health and longevity. Ashwagandha's classification as a Rasayana underscores its role in enhancing vitality, immunity, and overall wellness.
9) Disease:
Diseases are conditions that disrupt normal physiological functions. Ashwagandha has been researched for its therapeutic effects on various diseases, ranging from stress-related ailments to chronic conditions, showcasing its versatility in treatment.
10) Horse:
The association of Ashwagandha with 'horse' in its name comes from its properties believed to emulate the strength and vitality of horses. This connection emphasizes its use as a strength-enhancing tonic and its historical significance in promoting virility and endurance.
11) Ayurveda (Ayus-veda):
Ayurveda is an ancient Indian system of medicine that emphasizes balance in physical, mental, and spiritual health. It utilizes a holistic approach to wellness through natural remedies, dietary guidelines, and lifestyle practices, leveraging herbs like Ashwagandha to promote health and prevent disease.
12) Dravyaguna (Dravya-guna):
Dravyaguna is a branch of Ayurveda focusing on the study of medicinal substances. It involves understanding the properties, actions, and therapeutic applications of herbs like Ashwagandha. This knowledge is vital for practitioners to effectively prescribe treatments tailored to individual needs.
13) Honey:
Honey is often utilized in Ayurvedic formulations for its natural sweetness and healing properties. It enhances palatability and offers additional health benefits, serving as a natural preservative and a medium to carry herbal ingredients, improving their efficacy.
14) Withania somnifera:
Withania somnifera is the scientific name for Ashwagandha, a key herb in Ayurveda. This nomenclature helps in recognizing the species among various plants and establishes its place within scientific and medical research, reinforcing its therapeutic relevance.
15) Training:
Training in the context of Ayurveda refers to the education and preparation of practitioners in the principles and practices of Ayurvedic medicine. This systematic training ensures that practitioners can effectively apply herbal knowledge, including the use of Ashwagandha for various health issues.
16) Punjab:
Punjab is a region in India known for its rich agricultural practices, which include the cultivation of medicinal herbs like Ashwagandha. Its geographical and climatic conditions are conducive to growing such plants, contributing to traditional medicine in the area.
17) Balya:
Balya refers to strength-promoting attributes in Ayurveda. Ashwagandha is known for its Balya properties, enhancing physical performance, endurance, and vitality, particularly in individuals recovering from illness or those seeking to increase their strength and resilience.
18) Post:
In a medical context, 'post' usually refers to follow-up or subsequent stages in treatment or research. It may indicate post-treatment evaluations or the outcomes observed after incorporating Ashwagandha into therapeutic regimens.
19) Science (Scientific):
The term 'scientific' relates to the systematic methods of inquiry and research in healthcare. Investigating Ashwagandha's properties through scientific studies validates its traditional uses and informs modern applications.
20) Table:
In academic and research contexts, a 'table' refers to an organized arrangement of data presented systematically for clarity. Tables regarding Ashwagandha often display its properties, uses, or statistical results of research findings.
21) Drug:
Drugs, in a medical sense, refer to any chemical that alters physiological functions. Ashwagandha is viewed as a herbal drug, showing therapeutic potential for treating various health conditions through its unique chemical properties.
22) Sharkara (Sarkara):
Sharkara or jaggery is often used in Ayurvedic formulations for its sweetness and health benefits. It can complement the properties of herbs like Ashwagandha, enhancing absorption and providing additional nutritional benefits.
23) Debility:
Debility refers to physical weakness or a decline in strength and vitality. Ashwagandha is frequently recommended for individuals experiencing debility, assisting in recovery and boosting energy levels to restore well-being.
24) Madhura:
Madhura means sweetness in Ayurvedic terminology. It is a sensory quality that is associated with certain herbs and foods, including Ashwagandha when combined with other adjuncts like honey, making them more palatable and enhancing their effects.
25) Samhita:
Samhita refers to classical Ayurvedic texts that compile knowledge on herbal medicines, treatments, and philosophies. Ashwagandha is extensively mentioned in these texts, outlining its applications and significance in traditional healing systems.
26) Kshaya (Ksaya):
Kshaya, in Ayurveda, signifies the condition of emaciation or debility, commonly associated with chronic diseases. Ashwagandha is used to counteract Kshaya by promoting weight gain and vitality in affected individuals.
27) Vipaka:
Vipaka refers to the post-digestive effect of herbal substances in Ayurveda. Ashwagandha's Madhura Vipaka suggests it possesses sweet post-digestive properties, enhancing its benefits and suitability in various formulations.
28) Medhya:
Medhya refers to substances that enhance memory and cognitive function. Ashwagandha is categorized as a Medhya Rasayana, helping to improve cognitive performance and supporting mental clarity, especially in stressful conditions.
29) Family:
Family refers to the broader classification in biological taxonomy. Ashwagandha belongs to the Solanaceae family, which influences its characteristics and identifies its relation to other plants with similar properties.
30) Sugar:
Sugar is often included in Ayurvedic recipes for its sweetness and as a natural remedy. In formulations with Ashwagandha, sugar can enhance palatability while providing energy, supporting overall health.
31) Urustambha (Uru-stambha):
Urustambha refers to a condition affecting the lower body, often characterized by stiffness or immobility. Ashwagandha is utilized in treating this condition, demonstrating its therapeutic relevance in traditional medicine.
32) Nidranasha (Nidra-nasha, Nidranasa):
Nidranasha means insomnia or sleep disturbances in Ayurveda. Ashwagandha is noted for its calming properties, making it a common remedy to address sleep issues and promote restful sleep.
33) Harvesting (Harvest):
Harvesting is the process of collecting mature crops or plants. The timely harvesting of Ashwagandha roots is crucial for preserving their medicinal properties and optimizing their use in herbal formulations.
34) Shatavari (Satavari):
Shatavari, an important Ayurvedic herb, complements Ashwagandha in various formulations. It is primarily indicated for female health and fertility, often used alongside Ashwagandha to enhance overall reproductive health.
35) Vatarakta (Vata-rakta):
Vatarakta refers to a condition associated with joint pain and inflammation, similar to gout. Ashwagandha is traditionally used to alleviate these symptoms, demonstrating its anti-inflammatory and analgesic properties within Ayurveda.
36) Mahabhuta (Maha-bhuta):
Mahabhuta denotes the five great elements in Ayurveda—earth, water, fire, air, and space. Understanding these elements' interactions informs the use of plants like Ashwagandha within a holistic framework for health.
37) Rajasthan:
Rajasthan is a state in India known for agricultural diversity, including the cultivation of medicinal plants like Ashwagandha. Its environment supports various traditional medicinal practices in the region.
38) Pippali (Pippalin):
Pippali, or long pepper, is an Ayurvedic herb often used alongside Ashwagandha in formulations. It aids digestion and enhances the bioavailability of other herbs, contributing to their efficacy in treating various ailments.
39) Snigdha:
Snigdha refers to a quality of being unctuous or oily. In the context of Ashwagandha, it emphasizes its nourishing properties, enhancing its ability to promote health and treat conditions associated with dryness.
40) Species:
Species represent the fundamental unit of biological classification. Withania somnifera is the species name for Ashwagandha, emphasizing its unique characteristics and medicinal properties in scientific literature.
41) Akasha (Akasa):
Akasha refers to the space element in Ayurveda, signifying the foundation from which the other elements arise. In the context of herbs like Ashwagandha, it is important for understanding their holistic applications.
42) Manasa (Manasha):
Manasa is a region in India noted for its biodiversity and cultivation of medicinal plants. The traditional use of Ashwagandha in Manasa highlights local agricultural practices and their significance in herbal medicine.
43) Indian:
Indian denotes the geographical and cultural context from which Ashwagandha and other Ayurvedic practices originate. This heritage influences the understanding and application of herbs in traditional medicine systems worldwide.
44) Ulcer:
An ulcer is a sore or lesion that can cause pain or discomfort. Ashwagandha aids in managing ulcers by promoting healing; its anti-inflammatory properties make it relevant in treatment regimens for such ailments.
45) Karma (Karman):
Karma refers to action or activities in Ayurveda that determine the effects of treatments. The 'Karma' of Ashwagandha relates to its nurturing properties promoting health and wellness in patients.
46) Laghu:
Laghu denotes lightness in Ayurvedic terminology. This quality in Ashwagandha indicates its suitability for enhancing digestion and metabolism while providing nourishment without causing heaviness.
47) Tikta:
Tikta refers to bitterness in the context of Ayurvedic properties. This characteristic can contribute to digestive health and enhance the therapeutic profile in herbal formulations like Ashwagandha.
48) Ushna (Usna):
Ushna signifies warmth or heating properties in Ayurveda. Ashwagandha's Ushna attribute plays a role in its use for stimulating metabolism and improving circulation, supporting various health conditions.
49) Virya:
Virya refers to the potency or energy of a drug in Ayurveda. The Virya of Ashwagandha contributes to its efficacy as a rejuvenator and tonic in traditional healing practices.
50) Vrana:
Vrana signifies wounds or ulcers in Ayurvedic terms. Ashwagandha can be applied externally to support wound healing and mitigate inflammation, demonstrating its therapeutic versatility.
51) Water:
Water serves as a fundamental element in Ayurveda, used in various preparations and treatments. Mixing Ashwagandha with water enhances its digestion and bioavailability, assisting in its medicinal applications.
52) Study (Studying):
A study refers to research undertaken to investigate a particular phenomenon or substance. Studies on Ashwagandha explore its effects and validate its applications in modern and traditional herbal medicine.
53) Agni:
Agni signifies the fire element in Ayurveda, representing metabolic processes and digestive strength. The Agni of Ashwagandha indicates its ability to strengthen digestion and absorption, making it beneficial for overall health.
54) Katu:
Katu refers to the pungent taste and its properties in Ayurveda. This quality contributes to Ashwagandha's health benefits by aiding digestion and enhancing metabolic activities when included in herbal mixtures.
55) Rasa (Rasha):
Rasa means flavor or essence in Ayurveda, essential to understanding a herb's effects on the body. The Rasa of Ashwagandha influences its therapeutic uses, playing a key role in its adaptability in formulations.
56) Vayu:
Vayu symbolizes the air element in Ayurveda, governing movement and circulation. The Vayu qualities of Ashwagandha support its applications in treating conditions linked to vitiation of Vata dosha, enhancing overall health.
57) Guna:
Guna refers to attributes or qualities of substances in Ayurveda. Understanding Ashwagandha's Guna is crucial for practitioners to tailor treatments, ensuring they align with patients' health needs and specific conditions.
58) Jala:
Jala denotes the water element in Ayurveda, associated with the qualities of moisture and coolness. The Jala aspect of Ashwagandha complements its nurturing properties, enhancing its applications in health treatments.
59) Pain:
Pain is a physical sensation that indicates injury or illness. Ashwagandha is researched for its analgesic effects, offering potential relief for pain conditions and improving quality of life.
60) Male:
Male refers to the gender associated with Ashwagandha's traditional use as an aphrodisiac and strength tonic, which enhances male reproductive health and vitality while promoting overall well-being in men.
61) Cow urine (Cow's urine):
Cow's urine is considered a medicinal substance in Ayurveda, often used for purification and therapeutic purposes. In some formulations, it complements Ashwagandha, enhancing its effectiveness in various treatments.
62) clarified butter:
Clarified butter, or ghee, is a significant ingredient in Ayurvedic preparations. It aids in the absorption of Ashwagandha's benefits and provides nourishment, enhancing its medicinal properties when combined as a formulation.
63) Bronchial asthma:
Bronchial asthma is a respiratory condition characterized by airway inflammation. Ashwagandha is utilized in Ayurvedic treatments for asthma, helping to alleviate symptoms and improve overall respiratory health.
64) Cow milk (Cow's milk):
Cow milk is frequently used in Ayurveda as a base for herbal preparations. When combined with Ashwagandha, it enhances digestion, improves absorption, and adds nutritional value, supporting overall health.
65) Sushruta-samhita (Susruta-samhita):
The Sushruta Samhita is one of the foundational texts of Ayurveda detailing surgical techniques and medical practices. It serves as a reference for understanding the medicinal uses of Ashwagandha in ancient practices.
66) Madhuraskandha (Madhura-skandha):
Madhura-skandha is a term associated with sweetness elements in Ayurveda. In the context of Ashwagandha, it highlights its palatability and the pleasant qualities that enhance its use in therapeutic formulations.
67) Phytochemical:
Phytochemical denotes specific bioactive compounds in plants with health benefits. Ashwagandha's array of phytochemicals, including alkaloids and lactones, contributes to its diverse medicinal effects and therapeutic use.
68) Shankhapushpi (Sankhapuspi, Samkhapuspi):
Shankhapushpi is an Ayurvedic herb known for its cognitive-enhancing properties. It is often used in formulations alongside Ashwagandha to amplify mental performance and overall cognitive health.
69) Antibiotic (Antibacterial):
Antibacterial properties refer to the ability to combat bacterial infections. The antibacterial activities of Ashwagandha expand its therapeutic potential, making it suitable in treating infections and improving health outcomes.
70) Mandukaparni (Mamdukaparni, Manduka-parni):
Mandukaparni, also known as Gotu Kola, is an herb used in Ayurveda for cognitive enhancement. Often combined with Ashwagandha, it synergistically supports memory, focus, and overall brain health.
71) Vidarigandha (Vidari-gandha):
Vidarigandha is an Ayurvedic herb recognized for its rejuvenating properties. It is often utilized in combination with Ashwagandha in formulations aimed at enhancing vitality and overall well-being.
72) Chemotherapy:
Chemotherapy is a critical treatment for cancer, targeting rapidly dividing cells. Research indicates that Ashwagandha may complement chemotherapy, enhancing efficacy while minimizing side effects associated with conventional cancer treatment.
73) Inflammation:
Inflammation is the body's response to injury or illness. Ashwagandha is valued for its anti-inflammatory properties, making it beneficial in managing chronic inflammatory conditions and promoting overall health.
74) Mahaushadhi (Mahausadhi, Maha-aushadhi, Mahshadhi, Mahsadhi, Maha-oshadhi):
Mahaushadhi refers to potent medicinal herbs within Ayurveda. Ashwagandha is often classified as a Mahaushadhi owing to its extensive therapeutic applications and benefits in promoting health and healing.
75) Brimhaniya (Brmhaniya):
Brimhaniya denotes strengthening and nourishing qualities in Ayurvedic texts. Ashwagandha is recognized as Brimhaniya, enhancing vitality and supporting physical and mental health.
[Note: The above list is limited to 75. Total glossary definitions available: 132]
Other Science Concepts:
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