Comparative study of lac cameli vs. synthesis 9.1 in type 1 diabetes.
Journal name: World Journal of Pharmaceutical Research
Original article title: A comparative study for effectiveness of lac cameli with synthesis 9.1 repertory as adjuvant in cases of type 1 diabetes mellitus– a single blind randomised trial
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Original source:
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Dr. Narender Kumar and Dr. Aijaz Aziz Sulemani
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: A comparative study for effectiveness of lac cameli with synthesis 9.1 repertory as adjuvant in cases of type 1 diabetes mellitus– a single blind randomised trial
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr202211-25104
Copyright (license): WJPR: All rights reserved
Download the PDF file of the original publication
Summary of article contents:
Introduction
This study evaluates the effectiveness of Lac cameli compared to individualized homeopathic medicines in treating Type 1 Diabetes Mellitus (T1DM) in a single-blind randomized trial. Conducted at the MN Homoeopathic Medical College and Research Institute in Bikaner, 100 patients aged 5 to 60 years were randomly allocated into two groups, one receiving traditional homeopathic treatment and the other Lac cameli. The objective was to assess the impact of these treatments on HbA1c and fasting blood glucose levels, as well as anthropometric measurements over a year-long study period.
Effectiveness of Treatments
Results from the statistical analysis indicated that both individualized homeopathic treatments and Lac cameli significantly reduced fasting blood sugar (FBS) and HbA1c levels in patients. Group A (individualized homeopathic medicines) showed a reduction in FBS from an average of 199 mg/dL to 166.66 mg/dL, while Group B (Lac cameli) decreased from 200.02 mg/dL to 169.92 mg/dL. The decrease in HbA1c levels for Group A was from 7.85 to 7.45, and for Group B from 7.82 to 7.51. However, individualized homeopathic medicines were statistically significantly more effective than Lac cameli in addressing these parameters.
Statistical Analysis and Comparison
Using paired t-tests, the study analyzed pre- and post-treatment variables within both groups. The findings suggest substantial changes in FBS, HbA1c, and anthropometric measurements for both groups, with the most pronounced improvements observed in Group A. P-values indicated strong significance (p < 0.0001) for FBS and HbA1c reduction, thereby establishing the efficiency of individualized homeopathic treatment in managing T1DM. The data demonstrates that while both treatments offer benefits, the individualized approach appears to deliver superior results.
Patient Demographics and Treatment Base
The study involved a diverse cohort with an equal gender distribution and various socioeconomic backgrounds. Most participants were aged between 21-35 years, indicating a prevalence of T1DM in younger populations. The investigation found that both rural and urban regions were notably represented among the patients, reflecting the widespread challenge of diabetes in different environments. Treatments were delivered based on comprehensive patient evaluations, utilizing the Synthesis 9.1 repertory to identify the best-fitting individualized homeopathic remedies.
Conclusion
The study concludes that both individualized homeopathic medicines and Lac cameli can effectively manage Type 1 Diabetes Mellitus. However, the use of individualized homeopathic treatments yielded significantly better outcomes regarding reductions in fasting blood glucose levels, HbA1c, and anthropometric measures. The findings advocate for a tailored approach in homeopathic practice while acknowledging the limitations of the study, including small sample size and single-blinding. Future research with larger cohorts and robust methodologies is recommended to further explore these initial findings and enhance treatment strategies for T1DM.
FAQ section (important questions/answers):
What is the primary focus of this study?
The study focuses on comparing the effectiveness of Lac cameli and individualized homoeopathic medicines in managing Type 1 Diabetes Mellitus by analyzing changes in HbA1c and fasting blood glucose values.
How was the study designed and executed?
The study was a single-blind, randomized comparative trial involving 100 participants, divided into two groups, each receiving different treatments over a 12-month period with regular follow-ups.
What were the inclusion criteria for the study?
Participants included both sexes aged 5-60, patients with fasting blood sugar levels between 160-400 mg/dl, and freshly diagnosed insulin-dependent diabetes within 3-6 months.
What were the key findings regarding blood glucose levels?
Both treatment groups showed significant reductions in fasting blood sugar, but individualized homoeopathic medicines were found to be more effective than Lac cameli in improving outcomes.
What limitations were noted in the study?
The study noted limitations such as a small sample size, single blinding, and only one assessment scale used, suggesting that larger and longer studies are needed for more robust conclusions.
What recommendations were made for future research?
The authors recommend conducting double-blind trials with larger samples and extended durations to validate these findings and improve the methodology for better statistical analysis.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Comparative study of lac cameli vs. synthesis 9.1 in type 1 diabetes.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Study (Studying):
In the context of the provided text, 'Study' refers to the structured investigation carried out to assess the effectiveness of homoeopathic treatments, specifically Lac cameli and individualized medicines, in managing Type 1 Diabetes Mellitus (T1DM). It highlights the research method and findings that contribute to clinical knowledge and practice.
2) Medicine:
Similar to 'medicine,' 'Medicines' refers specifically to the various homoeopathic remedies or treatments utilized in the study. It highlights the importance of selecting appropriate formulas based on the individual patient's symptoms, potentially offering personalized care to those suffering from Type 1 Diabetes Mellitus.
3) Post:
'Post' in this study context refers to the evaluation phase after treatments have been administered. It signifies the follow-up assessments conducted to measure the outcomes of the treatments on patients' health metrics, such as fasting blood sugar and HbA1c levels, to determine efficacy.
4) Suffering:
The word 'Suffering' is used to describe the state of individuals living with Type 1 Diabetes Mellitus. It underscores the impact of the disease on patients' quality of life, emphasizing the need for effective treatments to alleviate their symptoms and improve overall health outcomes.
5) Measurement:
Similar to 'Measurement,' this term highlights the quantitative aspect of health indicators assessed during the study, including anthropometric measurements. These measurements provide essential data that supports understanding the physiological changes and impact of treatments in managing diabetes.
6) Table:
The term 'Table' refers to structured data presentations in the study, which include various statistical analyses and patient demographics. Tables are used to summarize findings effectively, allowing readers to visualize results and comparisons between different treatment groups in the investigation.
7) Family:
'Family' pertains to patients' background information, particularly their family history concerning Type 1 Diabetes Mellitus. Understanding familial relations is important as it may contribute to the risk factors associated with the disease and help provide targeted preventive measures or interventions.
8) India:
The mention of 'India' signifies the geographical and cultural context of the study, indicating that the research involves Indian populations. The prevalence and patterns of diabetes within this specific region add relevance to the findings, reflecting the local healthcare challenges and needs.
9) Male:
The term 'Male' references the gender distribution among study participants. Gender differences in disease prevalence, management, and response to treatment can be relevant factors influencing the outcomes of the study and the general understanding of Type 1 Diabetes.
10) Disease:
'Diseases' in the text refer to the broader category of health conditions that could encompass other comorbidities affecting diabetes management. This term highlights the complexity of health care in managing multiple conditions that can impact a patient's overall health strategy.
11) Indian:
This refers to the nationality or populace that is the subject of this study. The term 'Indian' underscores the cultural and regional factors that may influence the prevalence, diagnosis, and treatment of Type 1 Diabetes Mellitus within the context of Indian society.
12) Sugar:
'Sugar' in this context relates to glucose levels, which are critical in diabetes management. This word connects to the metabolic implications of diabetes, where sugar control is essential for preventing complications, thus highlighting the importance of the treatments in regulating blood sugar levels.
13) Blood:
The term 'Blood' is essential as it refers to the biological fluid monitored through tests such as fasting blood sugar and HbA1c in diabetes management. Monitoring blood parameters is vital for assessing the efficacy of the treatments provided during the study.
14) Relative:
In this context, 'Relative' refers to family members potentially having diabetes or health conditions. Understanding the genetic predisposition within relatives helps inform treatment options and risk assessments, driving targeted approaches in the management of Type 1 Diabetes Mellitus.
15) Village:
Similar to 'Villages,' this term represents the community context where patients reside. The village setting informs public health initiatives and understanding how geographical factors may affect diabetes prevalence, access to treatment, and overall health outcomes.
16) Company:
'Company' in this document most likely refers to good manufacturing practices within the context of homoeopathic medicine production. It emphasizes the importance of quality assurance in the supply of medicines used in the study, ensuring reliability and safety for patients.
17) Labour (Labor):
Here, 'Labour' might refer to participants' occupational backgrounds, indicating possible lifestyle factors that could influence diabetes risk. Understanding the impact of different job roles on health can be crucial for framing interventions and preventive measures in public health.
18) Kumar:
The name 'Kumar' denotes one of the authors of the study, providing credibility and authorship to the research findings. It emphasizes the collaborative effort of medical professionals in conducting and reporting the study on Type 1 Diabetes Mellitus.
19) Life:
'Life' in the document alludes to the overall existence and quality of patients living with Type 1 Diabetes Mellitus. This term encapsulates the broader implications of medical treatment and lifestyle management, emphasizing the goal of improving life quality for affected individuals.
20) Southern India:
Mentioning 'Southern India' places the study in a specific geographic context within India, indicating regional diabetes patterns. It highlights how local demographics and cultural factors may influence disease management, treatment accessibility, and prevalence rates.
21) Tuberculosis:
'Tuberculosis' is referred to under exclusion criteria for the study, identifying co-morbidities that may complicate diabetes management. Understanding such interactions informs medical professionals about the complexities of treating patients with multiple health conditions.
22) Discussion:
'Discussion' is a segment within the research paper where the authors interpret and analyze the significance of the study outcomes. This section contextualizes findings within existing literature, addressing implications for practice and future research directions regarding Type 1 Diabetes management.
23) Rajasthan:
The mention of 'Rajasthan' indicates the specific state in India where the study was conducted. This geographical context helps understand local diabetes prevalence, treatment practices, and public health considerations that may vary across different regions of India.
24) Attacking:
The term 'Attacking' relates to the autoimmune nature of Type 1 Diabetes, where the body's immune system mistakenly targets and destroys insulin-producing cells in the pancreas. Understanding this mechanism is crucial for comprehending the disease's pathophysiology and potential treatment approaches.
25) Pregnant:
In the context of this study, 'Pregnant' refers to a specific exclusion criterion. It emphasizes the importance of considering the safety and health implications for pregnant individuals while conducting research on treatments involving diabetes and homoeopathic medicines.
26) Habitat:
The term 'Habitat' highlights patients' living environments, such as urban versus rural areas. Understanding habitation patterns can provide insights into public health education and diabetes prevention strategies tailored to different community settings.
27) Burning (Burn, Burned, Burnt):
In the document, 'Burning' is one of the symptoms or complaints that could be associated with Diabetes Mellitus. It underscores the physical manifestations of the disease and highlights the need for effective treatment to alleviate symptoms experienced by patients.
28) Anxiety:
'Anxiety' appears within the complaints addressed in the study, signifying the psychological burden experienced by patients with chronic conditions like diabetes. Recognizing mental health issues is essential for providing holistic care and addressing the overall wellbeing of individuals.
29) Fever:
'Fever' may be mentioned among symptoms that patients experience, indicating potential infections or health complications in diabetic patients. It emphasizes the need for careful monitoring and management of diabetes alongside other health-related concerns.
30) Diet:
The term 'Diet' refers to the nutritional aspect essential in managing diabetes. Healthy dietary habits play a crucial role in controlling blood sugar levels, making it an integral part of treatment plans and lifestyle modifications for patients with Type 1 Diabetes.
31) Pain:
'Pain' is another symptom associated with diabetes that may affect patients. It highlights the need for comprehensive treatment approaches to mitigate various physical discomforts—the significance of which should not be overlooked in diabetes management.
32) Drug:
'Drug' in this text refers to any medicinal substances used to treat diabetes, including both conventional and homoeopathic options. The term underscores the importance of exploring different treatment modalities to improve patient care and outcomes in managing Type 1 Diabetes Mellitus.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Comparative study of lac cameli vs. synthesis 9.1 in type 1 diabetes.’. Further sources in the context of Science might help you critically compare this page with similair documents:
Statistical analysis, Follow-up, Research Institute, Sample size, Treatment Protocol, Fasting blood sugar, Ethical consideration, Inclusion and exclusion criteria, Clinical Practice, Demographic Data, HbA1c, Type 1 Diabetes mellitus, Adjuvant Treatment, Anthropometric measurement, Individualized Homoeopathic Medicine.