Study on medoroga management with panchatikta grita khseer basti.

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Journal name: World Journal of Pharmaceutical Research
Original article title: A clinical study on medoroga (obesity) and it”s management by “panchatikta grita khseer basti”
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Author:

Pallabi Mukherjee


World Journal of Pharmaceutical Research:

(An ISO 9001:2015 Certified International Journal)

Full text available for: A clinical study on medoroga (obesity) and it”s management by “panchatikta grita khseer basti”

Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research

Doi: 10.20959/wjpr202213-25662

Copyright (license): WJPR: All rights reserved


Summary of article contents:

Introduction

Obesity, a major health concern in contemporary society, significantly impairs health and quality of life. In Ayurveda, this condition correlates with "Medoroga," associated with the abnormal accumulation of fat (Medo Dhatu) in the body. The study presented investigates the efficacy of "Panchatikta Ghrita Ksheer Basti," a therapeutic method employed in Ayurveda, for managing obesity. Ten patients were selected based on specific criteria and treated over sixteen days to evaluate the clinical effects and statistical outcomes of the intervention.

Medoroga: The Ayurvedic Perspective on Obesity

In Ayurveda, Medoroga is characterized by an excess of Medo Dhatu and is linked to various lifestyle factors such as overconsumption of heavy foods, lack of physical activity, and even hereditary factors. It is underscored by symptoms including impaired bodily movement, weakness, and an increase in hunger and thirst. The Ayurvedic approach views obesity not only as excess weight but as a disruption in the balance of bodily doshas, particularly the Kapha dosha, which leads to metabolic disorders. Recognizing this holistic nature emphasizes the importance of targeted interventions for effective management.

Panchatikta Ghrita Ksheer Basti: Treatment Methodology

The study utilized "Panchatikta Ghrita Ksheer Basti," composed of five medicinal herbs known for their detoxifying and curative properties. Each herb in this preparation—Potol, Neem, Guruchi, Vasaka, and Saptachhada—possesses specific qualities that address obesity by cleansing the body of excess fat and improving metabolic functions. By administrating this treatment through enema (Basti), enhancements in digestive power and nutrient absorption were anticipated, potentially combating the core issues of Medoroga.

Research Findings and Statistical Analysis

The clinical study observed notable results following the administration of Panchatikta Ghrita Ksheer Basti. Statistical analysis revealed a significant reduction in Body Mass Index (BMI) among patients, with a t-value of 3.21 and a p-value less than 0.001, indicating that this treatment yields impressive outcomes in combating obesity. The mean and standard deviation recorded significant pre- and post-treatment variances, supporting the therapeutic effectiveness of this Ayurvedic intervention.

Conclusion

The study concludes that "Panchatikta Ghrita Ksheer Basti" is a safe and effective therapeutic approach to treat Medoroga, promoting weight reduction and overall metabolic health. This method, being cost-effective, provides a valuable alternative to conventional treatments for obesity. Future research may focus on refining these practices and establishing broader applications of Ayurvedic therapies to benefit individuals struggling with obesity and related disorders.

FAQ section (important questions/answers):

What is the focus of Mukherjee’s clinical study on obesity?

The study primarily examines the management of obesity, referred to as 'Medoroga' in Ayurveda, using the treatment 'Panchatikta Ghrita Ksheer Basti.'

How many patients were included in the study?

The study included ten patients selected based on specific inclusion and exclusion criteria from the outpatient department of J.B.Roy State Ayurvedic Medical College & Hospital.

What statistical method was used to analyze the results?

Statistical analysis was conducted using the Student's T-test, which indicated satisfactory results for the 'Panchatikta Ghrita Ksheer Basti' treatment.

What are the main ingredients in 'Panchatikta Ghrita Ksheer Basti'?

The formulation includes five main drugs: Potol, Neem, Vasaka, Guruchi, and Saptachhada, all known for their beneficial properties in managing obesity.

What was the significant outcome of the treatment?

After sixteen days of treatment, the Body Mass Index (BMI) of most patients significantly reduced, showing a statistically significant improvement (p value < 0.001).

Is 'Panchatikta Ghrita Ksheer Basti' safe for obesity treatment?

'Panchatikta Ghrita Ksheer Basti' is considered effective, safe, and cost-effective for treating 'Medoroga,' providing a viable option for managing obesity in patients.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Study on medoroga management with panchatikta grita khseer basti.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Basti:
Basti refers to a therapeutic enema used in Ayurveda for treating various conditions, predominantly in the management of diseases related to Vata dosha. It helps in cleansing the colon and balancing bodily elements, crucial for resolving issues like obesity, as mentioned in Medoroga. Its application, such as 'Anuvasana Basti' and 'Niruha Basti', demonstrates significant effects on metabolic disorders.

2) Medoroga (Medas-roga):
Medoroga translates to obesity in Ayurveda, correlating with the disturbance of Medodhatu, which is essential for fat metabolism. The condition leads to various health implications, affecting longevity and physical mobility, thus highlighting the need for efficient management like Pancha Tikta Ghrita Ksheer Basti in clinical studies.

3) Tikta:
Tikta, meaning 'bitter' in Sanskrit, refers to a taste that aids in digestion and weight management. It plays a vital role in the formulation of medicinal herbs like those in Panchatikta, assisting in reducing excess fat and purifying the body, crucial for treating conditions like Medoroga.

4) Ghrita (Ghrta):
Ghrita denotes clarified butter or ghee, which is an important medium for herbal formulations in Ayurveda. Used in Basti treatments, Ghrita helps enhance bioavailability of active herbal ingredients, contributing to effective management of obesity and ensuring the proper nourishment of tissues, while also balancing doshas.

5) Panca (Pancan, Pamca):
Pancha signifies the number five and is pivotal in Ayurveda to categorize five essential herbs in the context of Panchatikta Ghrita. This combination is crucial for addressing obesity (Medoroga) due to its synergistic effects that promote detoxification and metabolic balance, enhancing health outcomes.

6) Dhatu:
Dhatus are body tissues responsible for various physiological functions in Ayurveda. Their balance is essential for health; the disturbance in Dhatus, particularly Medodhatu, leads to conditions like obesity, emphasizing the importance of therapeutic interventions in restoring optimal health.

7) Disease:
A disease is a specific disorder characterized by a recognized set of signs and symptoms. In the context of this study, obesity or Medoroga is highlighted, emphasizing its implications on health and quality of life, thus identifying the importance of effective management strategies.

8) Drug:
Drugs in Ayurveda are medicinal substances, often derived from plants, used for therapeutic purposes. In the context of obesity treatment, the herbal components of Panchatikta play a vital role in effectively managing Medoroga, demonstrating the importance of traditional remedies in modern healthcare.

9) Tiktaghrita (Tikta-ghrita, Tiktaghrta):
Tikta-ghrita is a combination of the bitter properties of certain herbs and ghee, used in therapeutic preparations. This synergistic mix enhances digestion and fat metabolism, aiding in the treatment of obesity (Medoroga) and other metabolic disorders, demonstrating the depth of herbal formulations.

10) Study (Studying):
The study refers to the clinical research conducted to evaluate the effects of Panchatikta Ghrita Ksheer Basti on obesity. It highlights the research methodology, patient inclusions, treatment duration, and statistical findings, emphasizing the importance of empirical evidence in Ayurvedic practices.

11) Food:
Food in Ayurveda is viewed as a crucial component influencing health, especially concerning obesity. The consumption of unhealthy, energy-dense foods contributes significantly to weight gain, making dietary management fundamental in treating Medoroga, alongside herbal therapies like Basti.

12) Anuvasanabasti (Anuvasana-basti):
Anuvasana-basti refers specifically to the oil-based enema in Ayurveda used for nourishing and lubricating the body’s tissues. Its application in treating obesity illustrates its therapeutic value in managing metabolic disorders through enhancing tissue health and promoting balance.

13) Anuvasana:
Anuvasana denotes the technique of administering medicated oil through the rectum, which significantly aids in balancing bodily doshas. This method is crucial in conditions like Medoroga, as it nourishes and mitigates vitiated doshas, leading to improved metabolic health.

14) Ayurveda (Ayus-veda):
Ayurveda is an ancient holistic healthcare system from India that focuses on balance within the body, mind, and spirit. It offers a comprehensive approach to treat diseases like obesity through natural remedies, dietary management, and lifestyle adjustments, showcasing its relevance in modern health.

15) Rasayana (Rasa-ayana):
Rasayana refers to rejuvenation therapy in Ayurveda, aimed at enhancing overall vitality and longevity. Integrating Rasayana principles in the treatment of Medoroga assists in restoring balance, vitalizing dhatus, and promoting a healthier lifestyle.

16) Rasa (Rasha):
Rasa, meaning taste, forms the foundation of Ayurvedic pharmacology. The classification of herbal ingredients based on their predominant tastes, such as Tikta (bitter), plays a significant role in therapeutic formulations aimed at restoring health and managing conditions like obesity.

17) Dosha (Dosa):
Dosha represents the three fundamental energies (Vata, Pitta, Kafa) that govern physiological functions in the body. In managing obesity, balancing doshas is critical, as imbalances can lead to excess fat accumulation and associated health risks.

18) Vata:
Vata is one of the three dosas that embodies air and space, associated with movement and circulation. In obesity management, regulating vata is crucial as its imbalance can exacerbate fat accumulation and metabolic disorders, illuminating the need for targeted therapies.

19) Vayu:
Vayu represents the vital air element in Ayurveda, integral to bodily functions. Imbalances in Vayu lead to metabolic disturbances, notably obesity. Treatments focusing on harmonizing Vayu, like Basti therapies, illustrate the holistic approach of Ayurveda in addressing such health issues.

20) Life:
Life in Ayurveda embodies the interconnectedness of physical, mental, and spiritual health. Addressing conditions like Medoroga not only emphasizes physical wellbeing but also the enhancement of quality of life, reflecting Ayurveda's comprehensive health paradigm.

21) Niruhabasti (Niruha-basti):
Niruha-basti refers to therapeutic enemas using watery or decoction-based substances aimed at detoxification. This treatment method is highly relevant in obesity management as it facilitates the removal of excess dosha and toxins, supporting the restoration of metabolic balance.

22) Bastikarman (Basti-karma, Basti-karman, Bastikarma):
Bastikarma denotes the therapeutic procedure of administering enemas in Ayurveda. This technique serves to regulate Vata dosha, enhance metabolic processes, and assist in conditions such as obesity, demonstrating the importance of this method in Ayurvedic practice.

23) Kandughna (Kandu-ghna):
Kandughna refers to the property of alleviating itching, often associated with various skin conditions. In the context of obesity and Medoroga, the attention to properties like Kandughna of certain herbs illustrates the multifaceted approach of Ayurveda in treating diverse health issues.

24) Pittahara (Pitta-hara):
Pittahara denotes the property that helps in pacifying pitta dosha. Incorporating Pittahara herbs in obesity treatments acknowledges the often-overlooked influence of pitta in metabolic disorders, demonstrating the holistic perspective of Ayurveda on health and disease.

25) Purusha (Purusa):
Purusha refers to a person or human form in Sanskrit. In Ayurveda, understanding the individual constitution (Prakriti) is vital for personalized treatment, especially in managing disorders like obesity, emphasizing the individualized approach of Ayurvedic medicine.

26) Lekhana:
Lekhana signifies the property of scraping or reducing excess tissue, particularly fat. In obesity management, the Lekhana property of specific herbs stresses the significance of using appropriate herbal formulations to correct metabolic imbalances and assist in weight management.

27) Quality:
Quality in healthcare contexts relates to the overall state of health and wellbeing of an individual. The study seeks to enhance the quality of life for patients suffering from obesity through effective Ayurvedic interventions, promoting holistic health practices.

28) Vasaka (Vashaka):
Vasaka, or Adhatoda vasica, is an important herb in Ayurveda known for its capability to manage respiratory issues and, in obesity treatments, helps in balancing kafa dosha. Its properties thus contribute positively to metabolic health, making it a key component in formulations.

29) Srotas (Shrotas):
Srotas refer to channels or pathways in the body responsible for the flow of nutrients and elimination of waste. In Ayurveda, ensuring proper function of srotas is crucial for health, particularly in managing obesity, as it aids in achieving balance within the bodily systems.

30) Niruha:
Niruha indicates the type of enema that uses a decoction or liquid substance for therapeutic effects. Administering Niruha Basti in obesity treatment serves to cleanse and detoxify the body, directly addressing dosha imbalances linked to excess adiposity.

31) Family:
Family refers to the taxonomy or classification of plants in Ayurveda, essential for understanding their medicinal properties. Recognizing the family of herbs aids in selecting appropriate remedies for conditions like Medoroga, emphasizing the systemic approach of Ayurvedic treatments.

32) Karma (Karman):
Karma translates to action or function in Ayurveda, often denoting the therapeutic role of a substance or treatment. Understanding the Karma of herbs and therapies like Basti reinforces their application in practical administration, particularly in managing diseases like obesity.

33) Medas (Meda, Medash):
Meda is a term in Ayurveda referring specifically to bodily fat or adipose tissue. The study of Meda focuses on its functional balance, highlighting the implications of excess fat in conditions like obesity, thus necessitating targeted herbal interventions.

34) Roga:
Roga means disease or disorder. In the context of the study, it represents conditions like Medoroga that require specific therapeutic attention. Understanding Roga aids in framing effective treatment paradigms in Ayurvedic practice.

35) Agni:
Agni denotes the digestive fire in Ayurveda, responsible for metabolism and overall health. Its impairment is central to conditions like obesity, necessitating treatments that enhance Agni to restore balance and support healthy metabolic processes.

36) Tinospora cordifolia:
Tinospora cordifolia, known as Guruchi in Ayurveda, is renowned for its immunomodulatory properties. Its inclusion in treatments like Panchatikta underscores its role in managing obesity, providing holistic support in restoring metabolic function and promoting overall health.

37) Azadirachta indica:
Azadirachta indica, or Neem, is a powerful herb in Ayurveda with numerous therapeutic benefits, including its role in managing doshas. In obesity treatment, Neem’s properties enhance metabolic processes, aiding in weight management and reinforcing its significance within the Panchatikta formulations.

38) Adhatoda vasica:
Adhatoda vasica, commonly known as Vasaka, is valued for its medicinal properties, particularly in respiratory health. Its inclusion in Ayurvedic treatments for obesity highlights its ability to balance kafa dosha and assist in metabolic regulation.

39) Trichosanthes dioica:
Trichosanthes dioica, or Potol, is an important herb used in Ayurvedic medicine, valued for its effects on digestive health. Its role in formulations aimed at obesity treatment illustrates the therapeutic approach of utilizing diverse herbs to address metabolic imbalances.

40) Dahaprashamana (Dahaprasamana, Daha-prashamana):
Daha-prasamana refers to properties that quell heat or inflammation in the body. In obesity management, utilizing herbs with this action helps mitigate inflammation, promoting better health outcomes as shown in Ayurvedic treatment paradigms.

41) Daurgandhya:
Daurgandhya means foul body odor caused by metabolic disturbances. In treating obesity, addressing Daurgandhya helps restore overall bodily harmony and health, illustrating the comprehensive nature of Ayurveda in tackling symptoms linked with metabolic disorders.

42) Tridoshahara (Tridosahara, Tridosha-hara):
Tridosahara denotes the ability to pacify the three doshas (Vata, Pitta, Kafa). Integrating Tridosahara herbs in obesity treatments underlines their multifaceted functions in restoring balance across multiple physiological systems, crucial for holistic health.

43) Agnimandya (Agni-mandya, Agnimamdya):
Agnimandya refers to the diminished digestive fire, commonly seen in obesity. Restoring Agni is essential for managing weight and metabolic health as it impacts nutrient absorption and overall vitality, highlighting its significance in Ayurvedic therapeutics.

44) Kushthaghna (Kusthaghna):
Kusthaghna refers to substances with properties to mitigate skin diseases. In the context of managing obesity, the relevance of Kusthaghna emphasizes a holistic approach to treatment, addressing underlying skin and metabolic issues simultaneously.

45) Katutikta (Katu-tikta):
Katu-tikta signifies a bitter and pungent taste, providing remarkable digestive benefits. Herbs with Katu-tikta properties are beneficial in obesity management as they enhance digestion, stimulate appetite regulation, and support overall metabolic health.

46) Discussion:
Discussion refers to the exploration and analysis of findings in the study. It highlights the importance of understanding the mechanisms behind treatments like Panchatikta Ghrita Ksheer Basti in managing conditions like Medoroga, fostering further research and application in Ayurvedic practice.

47) Developing:
Developing conveys the ongoing process of enhancing knowledge and methodologies in Ayurveda. Continuous research in the efficacy of treatments like Panchatikta Ghrita for Medoroga signifies the growth of traditional practices integrating with modern science, aiming for better health outcomes.

48) Samprapti:
Samprapti denotes the pathogenesis or progression of a disease in Ayurveda. Understanding the Samprapti of Medoroga aids clinicians in formulating targeted interventions, illustrating the significance of this principle in creating effective treatment strategies.

49) Prashamana (Prasamana):
Prasamana refers to the soothing or alleviating properties of a substance. In managing obesity, using herbs that provide Prasamana effects can reduce discomfort associated with excess weight, supportive in enhancing overall health and patient comfort.

50) Shaithilya (Saithilya):
Saithilya describes the condition of looseness or flaccidity that can affect bodily movement. In obesity, managing Saithilya is crucial as it can hinder mobility; thus, targeted treatments aim to restore strength and functionality in affected individuals.

51) Atisthula (Ati-sthula):
Atisthula refers to a person with excessive body mass or obesity. Recognizing Atisthula in Ayurveda establishes a framework for understanding the implications of excess weight, emphasizing the significance of targeted treatments to address this health concern.

52) Suffering:
Suffering denotes the physical and psychological distress associated with health conditions like obesity. The study emphasizes alleviating suffering through effective Ayurvedic treatments, establishing a holistic vision of improving patient wellbeing and quality of life.

53) Nighantu (Nighamtu):
Nighantu refers to the Ayurvedic lexicon that categorizes medicinal plants and their properties. Utilizing the Nighantu aids practitioners in selecting appropriate herbs for treatment, reinforcing the systematic knowledge essential for effective management of conditions like Medoroga.

54) Vatahara (Vata-ahara):
Vatahara denotes actions or substances that pacify Vata dosha, essential for balance in bodily functions. In obesity management, Vatahara properties help mitigate excess fat accumulation and restore metabolic harmony, illustrating the holistic nature of Ayurvedic practices.

55) Vatadosha (Vatadosa, Vata-dosha):
Vatadosa represents the air element responsible for movement and metabolism in Ayurveda. Imbalances in Vatadosa significantly contribute to obesity development, highlighting the importance of therapeutic strategies targeting Vata in treatment protocols.

56) Medicine:
Medicine refers to the science and practice of diagnosing, treating, and preventing diseases. The Ayurvedic approach in this study signifies a blend of traditional and holistic methodologies in addressing obesity, enriching the understanding of effective treatment options.

57) Activity:
Activity refers to physical movement and exercise, crucial for maintaining health. Lack of activity contributes significantly to obesity, emphasizing the need for lifestyle modifications alongside herbal treatments in managing conditions like Medoroga.

58) Vitiation (Vitiated):
Vitiated indicates the disruption or imbalance of doshas leading to disease. In this study, recognizing vitiated doshas is essential for understanding conditions like obesity and framing relevant therapeutic interventions to restore balance.

59) Sanskrit:
Sanskrit is the ancient language of India, often used in Ayurvedic texts to describe principles, treatments, and herbal formulations. Understanding Sanskrit aids in grasping the depth and richness of Ayurvedic wisdom, essential for practitioners and researchers alike.

60) Nindita (Nimdita):
Nindita refers to those criticized or denounced, in this context related to overweight individuals. This term emphasizes the need for compassionate approaches in managing obesity, shedding light on societal attitudes towards those suffering from conditions like Medoroga.

61) Vyavaya:
Vyavaya means sexual intercourse in Ayurveda, and its lack contributes to health issues including obesity. Recognizing the role of lifestyle factors in conditions like Medoroga underscores the complexity of treatment strategies that integrate physical and psychological health.

62) Dipana:
Dipana refers to substances that stimulate digestive fire (Agni), enhancing the body’s ability to metabolize food effectively. Incorporating Dipana properties in obesity management ensures optimal digestion and nutrient absorption, critical for treatment efficacy.

63) Koshtha (Kostha):
Kostha denotes the digestive tract or abdomen in Ayurveda, crucial for digestion and metabolic health. Addressing issues within the Kostha through treatments like Basti is vital in managing obesity, underscoring its importance in holistic care.

64) Cancer:
Cancer is a serious disease characterized by uncontrolled growth of abnormal cells. Acknowledging serious ailments like cancer during the study emphasizes the necessity for caution and personalized approaches in managing obesity, reflecting the holistic nature of Ayurvedic treatment.

65) Seat (Seated):
Seated refers to the position of the doshas and dhatus in the body. Understanding how these elements are seated provides insight into the workings of obesity and related disorders, emphasizing the interrelation of body systems in health.

66) Virya:
Virya denotes the potency or strength of an herb or substance in Ayurveda. Understanding the Virya of constituents in Panchatikta assists practitioners in determining the effectiveness of treatments for obesity, shaping therapeutic interventions.

67) Kshaya (Ksaya):
Ksaya refers to depletion or loss in Ayurveda. In the context of obesity, managing Ksaya involves strategies to rebuild and restore the body’s strength and vitality, highlighting the integral role of balance in maintaining health.

68) Kheer:
Kheer usually indicates a sweet dish made from rice and milk. In Ayurvedic contexts, variations may include medicinal properties that contribute positively to health, emphasizing the importance of dietary choices in managing conditions like obesity.

69) Sugar:
Sugar refers to simple carbohydrates commonly found in foods, and its excessive intake is a significant factor contributing to obesity. Understanding the role of sugar in diets aids in crafting effective nutritional strategies in obesity management.

70) Table:
Table indicates the organization of data or findings, often used in research to convey results succinctly. In the study context, data tables effectively illustrate the outcomes of treatments, enhancing clarity and understanding of the research results.

71) Field:
Field refers to a specific area of study or profession. In this context, the field of Ayurvedic medicine is explored, demonstrating its significance and application in contemporary healthcare, especially concerning obesity management and holistic wellbeing.

72) Guru:
Guru reflects greatness in terms of knowledge, often associated with teachers and mentors in Ayurveda. This term reinforces the traditional transmission of Ayurvedic wisdom, emphasizing the complexity and depth of this healing discipline.

73) Katu:
Katu denotes the pungent taste, enhancing digestion and metabolic processes. Integrating Katu properties in obesity management enhances appetite regulation, thus playing an influential role in comprehensive treatment approaches within Ayurveda.

74) Sara (Shara):
Sara refers to the essence or vitality of the dhatus. Recognizing the importance of Sara in Ayurveda helps inform treatment strategies for obesity, illustrating the management of essential nutrients for optimal health.

75) Ushna (Usna):
Usna refers to properties associated with warmth or heating effects in Ayurveda. Using Usna substances in managing obesity can stimulate digestion and metabolic processes, thereby restoring balance and aiding weight management.

[Note: The above list is limited to 75. Total glossary definitions available: 79]

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Medoroga, Daurgandhya, Panchatiktaghrita, Niruhabasti, Anuvasanabasti, Tikta Rasa, Statistical analysis, Sedentary lifestyle, Basti therapy, Body mass index (BMI), Hereditary factor, Kafa dosha, Asta Nindita Purusha, Lack of physical exercise, Obesity impact.

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