Journal name: World Journal of Pharmaceutical Research
Original article title: Effect of herbal formulation navkarshik ghan vati in the management of vatarakta w.s.r. to gout
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Subtitle: a case report
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Hem Raj, Balbir Singh and Manju Saini
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Effect of herbal formulation navkarshik ghan vati in the management of vatarakta w.s.r. to gout
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr202215-25961
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Summary of article contents:
Introduction
Vatarakta, known as gout, is a widespread metabolic disorder that has become increasingly common in modern society due to sedentary lifestyles and changing dietary habits. The condition is defined by elevated uric acid levels leading to inflammatory arthritis, marked by severe pain, tenderness, and swelling in the affected joints. The incidence of gout has markedly increased across the globe, with a prevalence rate of 6.8% reported in India. The present case report involves a 44-year-old male patient who experienced acute pain and redness in the left metatarsophalangeal joint and ankle, corroborated by elevated uric acid levels.
Herbal Treatment Evaluation
The patient was treated with Navkarshik Ghan Vati, an Ayurvedic formulation consisting of several herbs including Nimba, Manjistha, Vacha, and others known for their therapeutic properties. This formulation aims to relieve symptoms associated with Vatarakta, such as joint pain and swelling. Administered over a two-month period, significant clinical improvements were observed, particularly in the patient's subjective symptoms. The pain and redness were substantially reduced, indicating the effectiveness of this herbal remedy in managing gout.
Patient Case Details
The patient presented with specific symptoms including pain in the left metatarsophalangeal joint and ankle, alongside a notable history of hypertension, dyslipidemia, and hypothyroidism. Initial medical treatments included fever reducers and medications to lower uric acid levels, which the patient later discontinued. As the symptoms resurfaced, the patient opted for Ayurvedic treatment, leading to a thorough examination that confirmed symptoms consistent with gout, including redness and swelling in the joints. The patient's family medical history was relevant, particularly with cardiovascular issues.
Clinical Outcomes
Upon the initiation of treatment with Navkarshik Ghan Vati, the patient exhibited marked improvement in symptoms within the first week. By the end of the two-month trial, there was a significant reduction in pain, swelling, redness, and stiffness, with the patient's serum uric acid levels decreasing from 9.6 mg/dl to 5.6 mg/dl. The observed improvement in the patient's condition was evaluated through subjective assessments of pain and swelling and objective measures like serum uric acid levels, validating the efficacy of the herbal treatment.
Conclusion
Navkarshik Ghan Vati proves to be an effective traditional therapy for managing Vatarakta (gout), demonstrating significant reductions in symptoms and serum uric acid levels in the treated patient. This herbal formulation, recognized for being affordable and well-tolerated with minimal side effects, emphasizes the potential of Ayurvedic treatments in alleviating the sufferings associated with gout. The outcomes advocate for further exploration of herbal medicines as viable alternatives for contemporary ailments like gout, particularly in populations experiencing lifestyle-related chronic conditions.
FAQ section (important questions/answers):
What is Vatarakta and how is it related to Gout?
Vatarakta is a common metabolic disorder leading to inflammation and pain in joints. It correlates with Gout, an abnormal purine metabolism condition causing high uric acid levels and inflammatory arthritis.
What herbal formulation was used in the case report?
The case report utilized Navkarshik Ghan Vati, composed of various herbs including Nimba, Manjistha, and Vacha, which are believed to help in managing symptoms of Vatarakta.
What were the symptoms of the patient mentioned in the case?
The patient experienced severe pain and redness in the left metatarsophalangeal joint and ankle joint, along with stiffness and elevated uric acid levels at 9.6 mg/dl.
How long was the treatment duration for the patient?
The patient was treated with Navkarshik Ghan Vati for a duration of two months, which resulted in significant symptom relief and reduction in uric acid levels.
What were the results after the treatment with Navkarshik Ghan Vati?
After two months of treatment, the patient showed marked improvement in joint pain, swelling, redness, and stiffness, with serum uric acid levels decreasing from 9.6 to 5.6 mg/dl.
Is Navkarshik Ghan Vati considered safe and effective?
Yes, Navkarshik Ghan Vati is effective, inexpensive, easily accessible, and has minimal to no complications, making it a suitable option for managing Vatarakta or Gout.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Effect of Navkarshik Ghan Vati on Vatarakta (Gout) management.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Pain:
Pain is a primary symptom experienced by patients with Vatarakta (Gout), often severe and acute, particularly in the affected joints like the metatarsophalangeal joint. It indicates inflammation and underlying metabolic issues, prompting individuals to seek treatment options such as Ayurvedic formulations like Navkarshik Ghan Vati.
2) Stiffness:
Stiffness refers to the inability to move joints freely, which can be a significant symptom in Vatarakta. Patients may experience stiffness, often along with pain and swelling, affecting their mobility and quality of life. Effective treatments aims to alleviate stiffness as part of symptom management.
3) Swelling:
Swelling in joints is characteristic of inflammatory conditions such as Vatarakta, and it points to increased fluid accumulation due to inflammation. Ayurvedic therapies target swelling, and observing its reduction is a positive indicator of treatment efficacy and recovery from the condition.
4) Disease:
The term diseases encompass a wide array of health conditions, including metabolic disorders. Understanding diseases aids in identifying risk factors, appropriate interventions, and the need for lifestyle modifications, crucial in managing disorders like Vatarakta and improving public health outcomes.
5) Sandhi (Shandhi, Samdhi):
In Ayurvedic terminology, 'Sandhi' refers to the joints of the body. It symbolizes the anatomical site where symptoms like pain, swelling, and stiffness manifest in conditions such as Vatarakta. This term helps practitioners categorize and understand musculoskeletal issues within Ayurvedic treatment methodologies.
6) Vatarakta (Vata-rakta):
Vatarakta is an Ayurvedic term for a condition akin to Gout, characterized by joint inflammation due to excess Vata dosha and elevated uric acid levels. Knowledge of Vatarakta is crucial for appropriate diagnosis, treatment, and understanding its implications on a patient's lifestyle.
7) Vati:
Vati is a dosage form in Ayurveda that comprises herbal powders compressed into pills. The term is significant as it often denotes specific formulations used for treatment, such as Navkarshik Ghan Vati, which is indicated for managing conditions like Vatarakta effectively.
8) Punjab:
Punjab is a region in India where the case report originates, contributing to local and cultural practices in Ayurvedic medicine. Understanding regional demographics and health challenges is important for tailoring effective treatment models, especially for conditions prevalent in specific populations.
9) Medicine:
Medicines encompass various substances used for healing and health management. Ayurvedic medicines like Navkarshik Ghan Vati cater to specific health issues, representing an alternative approach alongside modern medicine for treating conditions such as Vatarakta, facilitating integrative health strategies.
10) Shotha (Sotha):
Shotha means swelling in Ayurveda and pertains to the condition of inflammation and excess fluid retention in joints. Identifying shotha helps guide treatment plans that aim to reduce inflammation and thereby improve joint function and patient comfort.
11) Study (Studying):
Study denotes the research and observational context from which data and findings are derived. The clinical study sheds light on the effectiveness of Navkarshik Ghan Vati in managing symptoms and improving uric acid levels in patients with Vatarakta.
12) Kurukshetra (Kuruksetra, Kuru-kshetra):
Kurukshetra is a city in Haryana, India, known for its historical and cultural significance. In this context, it is relevant as the location of the Sri Krishna Ayush University, contributing to advancing Ayurvedic research and treatment methodologies like those applied in the case of Vatarakta.
13) Rasayana (Rasa-ayana):
Rasayana refers to rejuvenative therapies in Ayurveda aimed at promoting health and longevity. The incorporation of rasayana herbs in treatments enhances their potential benefits, indicating a holistic approach to managing diseases like Vatarakta through comprehensive dietary and herbal strategies.
14) Krishna (Krsna):
Krishna refers to Sri Krishna Ayush University, a prominent institution in Haryana dedicated to research and education in Ayurveda. It plays a vital role in promoting Ayurvedic practices for treating conditions like Vatarakta through academic and clinical training.
15) Ayus (Ayush):
Ayush is an acronym for traditional Indian systems of medicine: Ayurveda, Yoga, Unani, Siddha, and Homeopathy. It signifies the integrative approach to health and wellness in India, vital for treating chronic conditions such as Vatarakta through holistic methods.
16) Blood:
Blood testing, particularly for uric acid levels, is crucial in diagnosing conditions like Vatarakta. Understanding blood parameters informs treatment decisions and helps monitor progress, emphasizing the interplay between laboratory data and clinical evaluation in Ayurvedic practices.
17) Sign:
In medical terminology, 'sign' refers to observable indicators of a disease. Identifying the signs of Vatarakta helps clinicians evaluate the severity of the condition and model treatments effectively, emphasizing the importance of physical assessments in patient management.
18) Drug:
Drug in this context refers to the formulated medications used to address health issues. Navkarshik Ghan Vati is an example of an Ayurvedic drug designed to manage Vatarakta symptoms effectively, showcasing the role of herbal compounds in therapeutic applications.
19) Manjishtha (Manjistha, Mamjishtha):
Manjistha, an herb known for its blood-purifying properties, is utilized in Ayurvedic formulations like Navkarshik Ghan Vati. Its relevance lies in its ability to manage conditions associated with toxins in the body, aiding recovery in patients with Vatarakta.
20) Haritaki:
Haritaki is an important herb in Ayurvedic medicine known for its digestive and detoxifying properties. Its inclusion in formulations aimed at treating Vatarakta highlights its significance in addressing root causes of joint inflammation and promoting overall wellness.
21) Madhyama:
Madhyama refers to a moderate or balanced state in Ayurvedic texts. It is essential in understanding an individual's constitution (Prakriti) and their response to treatments, influencing how practitioners tailor interventions for optimizing health and managing conditions like Vatarakta.
22) Pariksha (Pariksa):
Pariksha signifies examination or assessment in Ayurveda. It emphasizes the necessity of thorough patient evaluation in diagnosing conditions such as Vatarakta, ensuring that treatment plans are effectively customized based on individual health profiles and symptomatology.
23) Amalaki:
Amalaki, or Indian gooseberry, is a potent herb in Ayurveda recognized for its antioxidant and rejuvenative properties. Its role in formulations for Vatarakta showcases the emphasis on using natural ingredients to promote healing and restore balance within the body.
24) Shakti (Sakti):
Shakti indicates the energy or strength within Ayurvedic principles. The concept is essential in understanding how vitality impacts health, guiding the development of treatment plans to strengthen the individual’s overall wellness and enhance recovery from conditions like Vatarakta.
25) Kutaki:
Kutaki is an herb used in Ayurveda known for its detoxifying and liver-supportive properties. Its presence in treatments for Vatarakta illustrates the herbal strategy employed to reduce metabolic disturbances, helping manage symptoms associated with joint inflammation.
26) Family:
Family refers to the patient's relatives and their health history, which can significantly impact an individual's health. In cases of Vatarakta, understanding family medical history provides insight into genetic predispositions and risk factors influencing disease manifestation.
27) India:
India is the birthplace of Ayurveda, reflecting a rich tradition of herbal medicine and holistic health practices. Knowledge about India’s healthcare landscape is crucial for understanding the historical context and contemporary applications of Ayurvedic treatments like those for Vatarakta.
28) Nimba:
Nimba, or Neem, is a revered herb in Ayurveda known for its anti-inflammatory and antimicrobial properties. Its inclusion in Ayurvedic formulations emphasizes the importance of utilizing natural ingredients to combat conditions like Vatarakta and promote overall health.
29) Pulse:
Nadi, or pulse examination, represents a diagnostic method in Ayurveda to assess the body’s condition. Understanding pulse characteristics aids practitioners in diagnosing ailments like Vatarakta, providing insight into the patient's health status and guiding treatment decisions.
30) Vaca:
Vacha, or calamus, is an herbal ingredient utilized in Ayurvedic medicine known for its anti-inflammatory and cognitive-enhancing properties. Its role in formulations for Vatarakta underscores the holistic approach in Ayurveda to address joint health and overall well-being.
31) Male:
The term male refers to the gender of the patient featured in the case study, providing context for demographic factors that may play a role in the prevalence and treatment of conditions like Vatarakta, shaping best practice approaches in clinical settings.
32) Tinospora cordifolia:
Tinospora cordifolia, known as Guruchi in Ayurveda, is celebrated for its immune-boosting and adaptogenic properties. Its application in treatments for Vatarakta illustrates the significance of using diverse botanicals to enhance therapeutic outcomes and promote patient health.
33) Emblica officinalis:
Emblica officinalis, or Amalaki, is highly valued in Ayurveda for its rejuvenative and antioxidant effects. The incorporation of this herb in treatments for Vatarakta reveals its importance in fostering recovery and enhancing the therapeutic efficacy of Ayurvedic formulations.
34) Azadirachta indica:
Azadirachta indica, commonly known as Neem, holds therapeutic significance in Ayurveda due to its anti-inflammatory and detoxifying properties. Its role in managing Vatarakta aligns with the holistic philosophy that underpins Ayurvedic practice, aiming to restore harmony within the body.
35) Terminalia chebula:
Terminalia chebula, or Haritaki, is an important herb in Ayurvedic medicine recognized for its detoxifying and digestive properties. Utilized in the context of Vatarakta treatment, it emphasizes the relevance of herbal ingredients in effective therapeutic formulations.
36) Berberis aristata:
Berberis aristata, or Daruhaldi, is known for its therapeutic properties, especially in liver health and inflammation management. Its inclusion in the treatment for Vatarakta highlights the focus on leveraging specific herbs to address metabolic disorders effectively.
37) Burning sensation:
Burning sensation is often reported by patients suffering from joint conditions like Vatarakta, exacerbating discomfort. Recognizing this symptom is essential for clinicians to assess treatment efficacy and adapt therapeutic approaches to improve patient experiences.
38) Rubia cordifolia:
Rubia cordifolia, known as Manjistha in Ayurveda, is recognized for its potent blood-purifying properties. Its integration into treatments for Vatarakta exemplifies the importance of using herbal ingredients to assist in metabolic cleansing and promote joint health.
39) Bronchial asthma:
Bronchial asthma is a chronic respiratory condition that can coexist with other diseases like Vatarakta. Awareness of comorbid conditions is vital for clinicians to develop comprehensive treatment plans that address both asthma management and joint health.
40) Terminalia bellirica:
Terminalia bellirica, known as Bibhitaki, is an herb valued in Ayurveda for its detoxifying properties. Its incorporation into formulations for Vatarakta underscores the holistic approach to treatment, focusing on optimal health through the use of diverse herbal remedies.
41) Madhyamasatva (Madhyama-satva):
Madhyama-satva relates to an individual's mental strength and stability in Ayurvedic assessment. Understanding this concept is important in developing personalized treatment strategies for reclaiming health in conditions like Vatarakta.
42) Acorus calamus:
Acorus calamus, or Vacha, is a revered herb in Ayurveda known for its cognitive benefits and anti-inflammatory properties. Its role in formulations for Vatarakta demonstrates a holistic strategy that values both mental and physical wellness.
43) Aharashakti (Aharasakti, Ahara-shakti):
Ahara-shakti refers to the strength derived from food, emphasizing the role of diet in maintaining health and managing diseases. This concept is crucial in guiding dietary recommendations for patients with conditions like Vatarakta.
44) Inflammation:
Inflammation is the body's response to injury or disease, commonly observed in conditions like Vatarakta. Understanding the mechanisms of inflammation is critical for devising effective treatment strategies aimed at reducing symptoms and promoting healing.
45) Measurement:
Measurement is a critical part of clinical evaluation, involving the quantification of health parameters. This is essential for detecting changes in health status and determining the effectiveness of therapies used for conditions like Vatarakta.
46) Observation:
Observation in medical practice refers to the diligent monitoring of a patient's symptoms over time. This practice is vital for healthcare professionals treating Vatarakta, allowing for timely adjustments to therapy based on ongoing patient assessments.
47) Developing:
Developing refers to the process of creating or improving therapeutic strategies. In the context of Vatarakta, developing effective treatments is essential for managing symptoms and helping patients regain quality of life through personalized care.
48) Education:
Education in the healthcare field emphasizes the importance of knowledge and training in managing disorders. Understanding the principles of Ayurvedic medicine and Vatarakta improves clinician competency and patient outcomes in treatment strategies.
49) Prakriti (Prakrti):
Prakriti, or constitution, reflects an individual's unique physical and mental characteristics in Ayurveda. Knowledge of a patient's prakriti aids healthcare professionals in customizing treatment plans that align with the individual's inherent traits for optimal health.
50) Sparsha (Sparsa):
Sparsha, meaning touch in Ayurveda, represents an essential sense for assessing a patient's condition. The tactile examination helps clinicians identify symptoms, such as tenderness in joints during Vatarakta assessments, informing treatment strategies effectively.
51) Vikriti (Vikrti):
Vikriti refers to the current health status and any deviations from an individual's prakriti, highlighting imbalances. Understanding a patient's vikriti is essential in Ayurvedic practice, particularly for developing targeted interventions in cases like Vatarakta.
52) Meeting:
Meeting signifies the context in which health professionals assess and plan patient care. In managing conditions like Vatarakta, meetings foster collaboration among practitioners, enhancing treatment decision-making through shared knowledge and insights.
53) Burning (Burn, Burned, Burnt):
Burning refers to the sensation often felt in inflamed joints affected by Vatarakta, exacerbating pain. Recognizing this symptom is imperative for creating effective treatment regimes that alleviate discomfort and improve patient mobility.
54) Anxiety:
Anxiety can arise due to chronic health conditions, such as Vatarakta, impacting a patient's mental and emotional well-being. Addressing anxiety through comprehensive treatment approaches is essential for improving overall patient outcomes and quality of life.
55) Pramana (Pramanas):
Pramana refers to the means of attaining knowledge or evidence in Ayurvedic philosophy. Understanding pramana is important in evaluating treatment effectiveness, ensuring that practices are based on solid evidence and align with holistic health objectives.
56) Shabda (Sabda):
Shabda, meaning sound or speech, in the clinical context reflects communication's role in diagnosis and patient interaction. Clear communication enhances understanding of symptoms and treatment responses in managing diseases like Vatarakta.
57) Akriti (Akrti):
Akriti denotes an individual's physical form or structure in Ayurveda, which is essential for evaluating overall health. Understanding akriti aids in customizing treatment strategies, especially for conditions like Vatarakta, where physical characteristics influence therapeutic approaches.
58) Edema (Oedema):
Oedema refers to the accumulation of excess fluid in tissues, commonly observed in inflammatory joint conditions. Recognizing and addressing oedema in Vatarakta treatment emphasizes the need for therapies that reduce swelling and restore balance in bodily functions.
59) Riding:
Riding refers to the sedentary lifestyle prevalent in modern society, contributing to health disorders including Vatarakta. Promoting lifestyle changes, such as reducing unhealthy riding habits, is essential in non-communicable disease prevention and management.
60) Thirst:
Thirst expresses a body's need for fluids, which can become accentuated in certain health conditions. Managing thirst and hydration is important in overall health, particularly for individuals experiencing metabolic disorders like Vatarakta.
61) Manju (Mamju):
Manju refers to one of the authors in the study, highlighting collaborative efforts in Ayurvedic research. Author contributions foster a comprehensive understanding of treatment methodologies and effectiveness through diverse perspectives in clinical observations.
62) Satva (Shatva):
Satva encompasses mental clarity and stability in Ayurveda, essential for overall well-being. Improving satva through treatments not only addresses physical symptoms of conditions like Vatarakta but also enhances the psychological resilience of patients.
63) Jihva:
Jihva references tongue examination in Ayurveda, an important diagnostic tool to assess overall health and digestive status. Observing the tongue aids practitioners in evaluating conditions such as Vatarakta, guiding effective treatment strategies.
64) Mutra:
Mutra refers to urination, which is an important parameter in Ayurveda for evaluating kidney function and metabolic processes. Monitoring mutra is essential in the context of Vatarakta patients, as uric acid levels can directly correlate to urinary excretion.
65) Ahara:
Ahara signifies food intake within Ayurveda, emphasizing the critical role of nutrition in health management. A balanced ahara is vital in preventing and managing conditions like Vatarakta, aligning dietary choices with metabolic health improvement.
66) Sugar:
Sugar, particularly in the context of blood glucose levels, plays a key role in determining metabolic health. Measuring sugar levels and managing intake are important for patients, especially those with comorbidities like Vatarakta and related metabolic disturbances.
67) Fever:
Fever can accompany inflammatory conditions such as Vatarakta, reflecting the body's immune response. Monitoring for fever in patients is crucial in clinical assessments to gauge the severity of inflammation and guide subsequent treatment approaches.
68) Vaya:
Vaya refers to aging or the age of the patient, an important factor in shaping health profiles. Understanding a patient's vaya aids in tailoring treatment strategies in Ayurveda, especially for conditions like Vatarakta, which may vary in presentation by age.
69) Nadi (Nadin):
Nadi, or pulse, serves as a diagnostic tool in Ayurveda, providing insights into a patient's health status. Pulse examination plays a key role in understanding conditions like Vatarakta, helping practitioners craft appropriate treatment plans.
70) Mala:
Mala denotes waste excretion in Ayurveda, including components such as stool and urine. Evaluating mala is essential for understanding digestive health and metabolic waste processing in patients with conditions such as Vatarakta.
71) Sara (Shara):
Sara relates to the essence or quality of bodily tissues in Ayurveda. Assessing saras helps in determining health status and guiding treatment for conditions like Vatarakta, where metabolic balance is critical for improving quality of life.
72) Sama (Shama):
Sama refers to balanced states in Ayurveda, emphasizing harmony in bodily functions. Achieving sama is vital for patients with Vatarakta, guiding treatment approaches to restore equilibrium and support overall health.
73) Food:
Food significantly impacts health and metabolism and plays a crucial role in Ayurvedic treatments. Understanding dietary choices and their interplay with conditions such as Vatarakta is essential for creating effective management strategies.
74) Diet:
Diet refers to the regulated intake of food, critical in managing health conditions. In Vatarakta, adherence to a balanced diet can help lower uric acid levels and reduce symptoms, showcasing the significance of nutrition in Ayurvedic medicine.
75) Fear:
Fear can manifest as emotional distress arising from chronic illness, influencing treatment adherence and patient outlook. Addressing fear through counseling and supportive measures is essential in healthcare, particularly for those facing conditions like Vatarakta.
[Note: The above list is limited to 75. Total glossary definitions available: 76]
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