Phytochemical screening of Erythroxylum monogynum Roxb.
Journal name: World Journal of Pharmaceutical Research
Original article title: Phytochemical screening and assessment of bioactive compounds on erythroxylum monogynum roxb. (red cedar)
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Dr. A. Logamadevi, C. Menaka, B. Mahalakshmi and T. Poongodi
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Phytochemical screening and assessment of bioactive compounds on erythroxylum monogynum roxb. (red cedar)
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr202216-26313
Copyright (license): WJPR: All rights reserved
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Summary of article contents:
Introduction
Erythroxylum monogynum, commonly known as Red Cedar, belongs to the Erythroxylaceae family and is predominantly found in the southern parts of India. This study aims to investigate the phytochemical properties of its wood through qualitative and quantitative analyses, focusing on the bioactive compounds present. These compounds have significant implications for health and medicine, making it essential to assess and document their presence and concentrations. The qualitative evaluation was conducted using various solvents, primarily methanol and acetone, to extract and identify the phytochemicals from the wood.
Phytochemical Analysis of Erythroxylum monogynum
The qualitative phytochemical analysis revealed a variety of bioactive compounds in the wood extracts of E. monogynum. The methanol extract demonstrated the presence of alkaloids, flavonoids, tannins, glycosides, steroids, reducing sugars, phenols, emodins, phlobatannins, gums, mucilages, and resins. In contrast, certain compounds such as terpenoids, saponins, proteins, and amino acids were absent in both the methanolic and acetone extracts. This identification of phytochemicals is significant as it establishes a foundation for understanding the therapeutic properties of the plant and paves the way for future studies aimed at its medicinal uses.
Quantitative Determination of Phytochemicals
Quantitative analysis of the phytochemicals showed that alkaloids were the most abundant, constituting 14.94% of the wood extract. Flavonoids were found at 3.3%, while the phenolic content was the least at 0.32%. This quantitative assessment is crucial as it highlights the specific concentrations of beneficial compounds, providing insight into the potential efficacy and application of E. monogynum in medicine. Alkaloids, known for their diverse medicinal properties, along with flavonoids and phenols, contribute significantly to the plant's therapeutic potential and warrant further investigation.
Medicinal Properties and Applications
E. monogynum has a rich history of medicinal use, attributed to the bioactive compounds extracted from its wood. These compounds are known for their various health benefits, including antibacterial properties, hepatoprotective effects, and applications in treating diabetes, rheumatoid arthritis, and skin diseases. The aroma of sandalwood present in the wood oil also positions it as a valuable ingredient in perfumery. The findings underscore the broader implications of the medicinal applications of this plant, reinforcing its importance in traditional and modern medicine.
Conclusion
The phytochemical study of Erythroxylum monogynum has revealed a promising array of bioactive compounds with significant therapeutic benefits. The presence of various phytochemicals, particularly alkaloids, flavonoids, and phenols, highlights the plant's potential in health care and wellness. Nevertheless, it is essential to conduct more detailed research to isolate and characterize these bioactive compounds further. Such studies could enhance understanding of their specific health benefits and lead to the development of new medicinal applications derived from this valuable natural resource.
FAQ section (important questions/answers):
What is Erythroxylum monogynum and where is it found?
Erythroxylum monogynum, also known as Red Cedar, is a medicinal plant commonly found in southern India, particularly in Tamil Nadu, Kerala, Andhra Pradesh, and Karnataka.
What bioactive compounds were identified in E. monogynum wood?
The qualitative analysis of E. monogynum wood revealed alkaloids, flavonoids, tannins, glycosides, steroids, reducing sugars, phenols, and other compounds. Terpenoids, saponins, proteins, and amino acids were absent.
How were the bioactive compounds extracted from E. monogynum?
Bioactive compounds were extracted using methanol and acetone solvents through a process involving thorough washing, drying, pulverizing the wood, and subsequent extraction and evaporation to obtain crude extracts.
What were the results of the quantitative phytochemical analysis?
The quantitative analysis found alkaloids at 14.94%, flavonoids at 3.3%, and phenolic content at 0.32%, indicating that alkaloids were the most abundant bioactive compounds.
What medicinal properties are associated with E. monogynum?
E. monogynum has various medicinal benefits, including antibacterial effects, liver protection, and treatment for diabetes. Its infusion is traditionally used for diuretic and stomach issues.
What further studies are suggested for E. monogynum?
Further studies are recommended for the isolation and characterization of specific bioactive compounds in E. monogynum, which may reveal potential therapeutic applications for various diseases.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Phytochemical screening of Erythroxylum monogynum Roxb.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Phytochemical:
Phytochemicals are biologically active compounds found in plants that contribute beneficial properties beyond basic nutrition. They play important roles in plant defense and may influence human health significantly, potentially offering protective effects against diseases. The study focuses on identifying these compounds to evaluate their health benefits, particularly in traditional medicine.
2) Flavonoid:
Flavonoids are a class of phytochemicals known for their diverse biological activities. These compounds possess antioxidant properties and may help reduce the risk of chronic diseases such as cancer and cardiovascular diseases. Their presence in the studied plant, Erythroxylum monogynum, highlights its potential medicinal value and therapeutic applications.
3) Water:
Water is a vital solvent in biological processes, crucial for plant growth and extraction methods used in phytochemical analysis. In this study, water is used to prepare plant extracts and conduct several tests to identify bioactive compounds. The solubility of various phytochemicals in water facilitates qualitative and quantitative analyses.
4) Sugar:
Sugars are carbohydrates that serve as an energy source in living organisms. In the context of the study, reducing sugars are analyzed as part of the phytochemical screening of Erythroxylum monogynum. The presence of these compounds may indicate the plant's nutritional value and its potential role in traditional medicine.
5) India:
India is a country rich in biodiversity and traditional medicinal practices. The study focuses on Erythroxylum monogynum, commonly found in southern India. This geographical context emphasizes the use of local plant species in traditional medicine and the importance of exploring their phytochemical properties for potential health benefits.
6) Study (Studying):
The study investigates the phytochemical composition of Erythroxylum monogynum, aiming to evaluate the presence and concentration of bioactive compounds. Such research is essential for understanding the medicinal potential of the plant, supporting its use in traditional practices, and advancing modern pharmacological applications.
7) Medicine:
Medicines encompass a wide range of substances used for therapeutic purposes. The study investigates how the phytochemicals found in Erythroxylum monogynum may contribute to medicinal applications, potentially leading to improved health outcomes and offering insights for integrating local plant species into modern therapeutic practices.
8) Table:
A table presents organized data summarizing the qualitative and quantitative results of phytochemical analysis. In this study, tables are used to compare the presence of various compounds in methanolic and acetone extracts, facilitating easy comprehension of the findings and their implications for medicinal properties.
9) Disease:
Diseases encompass various disorders that affect organisms, creating a need for effective treatments. The focus of the study on Erythroxylum monogynum’s phytochemicals contributes to understanding their potential in preventing and treating diseases, validating traditional use and informing future pharmaceutical developments.
10) Botany:
Botany is the branch of biology that studies plants, including their structure, function, ecology, and taxonomy. The study related to Erythroxylum monogynum is grounded in botanical research, focusing on the identification of phytochemicals and their biological significance, thereby contributing to our understanding of plant properties.
11) Rheumatoid arthritis:
Rheumatoid arthritis is a chronic inflammatory disease that affects joints and can cause pain, swelling, and disability. The study highlights the medicinal properties of Erythroxylum monogynum, suggesting potential benefits in treating ailments like rheumatoid arthritis, further validating the therapeutic applications of certain plant-based compounds.
12) Tamilnadu (Tamil-nadu):
Tamil Nadu, sometimes stylized Tamil-nadu, refers to the same Indian state where Erythroxylum monogynum is found. Emphasizing this region highlights the local importance of the plant and its traditional uses in medicine, contributing to the understanding of regional biodiversity and herbal practices.
13) Family:
Family refers to a taxonomic rank in biological classification. Erythroxylum monogynum is categorized within the Erythroxylaceae family, which is significant from a botanical standpoint as it may indicate shared evolutionary traits. This classification aids in understanding the plant's characteristics and its potential uses in medicine.
14) Powder:
Powder in this context refers to the finely ground form of plant material used for extraction during the study. The powdered state enhances the solvent's ability to extract phytochemicals, facilitating the qualitative and quantitative analysis of bioactive compounds in Erythroxylum monogynum.
15) Drug:
A drug is any chemical substance that produces a physiological effect when introduced into the body. The findings of the study may contribute to understanding how specific compounds in Erythroxylum monogynum could be formulated into new therapeutic drugs, emphasizing the importance of plant-based research in pharmacology.
16) Antibiotic (Antibacterial):
Antibacterial refers to substances that inhibit bacterial growth or kill bacteria. The study highlights Erythroxylum monogynum's potential antibacterial properties, suggesting its usefulness in treating infections. Understanding its bioactive compounds contributes to the development of natural antibacterial agents within traditional medicine frameworks.
17) Discussion:
Discussion in a research context involves interpreting and analyzing results. In this study, the discussion section encompasses insights drawn from qualitative and quantitative analyses of phytochemicals in Erythroxylum monogynum, suggesting implications for medicinal properties and informing future research directions.
18) Karnataka:
Karnataka is another state in southern India where Erythroxylum monogynum is also found. The inclusion of Karnataka in the study underlines the geographic distribution of the plant and reinforces the importance of understanding the variety of phytochemicals across different habitats in traditional medicine.
19) Quality:
Quality in the context of this study refers to the presence and concentration of bioactive compounds within Erythroxylum monogynum, which are essential for assessing its medicinal value. Understanding the quality of plant extracts aids in establishing standards for effective herbal products and ensuring efficacy.
20) Species:
Species is a fundamental category of biological classification, grouping organisms capable of interbreeding. Erythroxylum monogynum represents a specific species of interest in the study, highlighting its unique phytochemical profile and potential uses in traditional medicine, contributing to our understanding of plant diversity.
21) Kerala:
Kerala is a southern Indian state known for its rich biodiversity and medicinal flora, similar to Tamil Nadu. Including Kerala emphasizes the geographic range of Erythroxylum monogynum and reinforces the importance of studying local plant species in understanding their phytochemical properties and traditional uses.
22) Andhra (Amdhra):
Andhra Pradesh is another southern Indian state where Erythroxylum monogynum is found. Mentioning Andhra highlights the regional distribution of this plant species, underlining the significance of traditional knowledge and practices in utilizing local flora for medicinal purposes.
23) Purity:
Purity in this study refers to the quality and integrity of the extracted phytochemicals from Erythroxylum monogynum. Ensuring purity is crucial for validating the efficacy of the extracts in medicinal applications, as contaminants or adulterants could affect the natural therapeutic properties of the plant.
24) Aroma (A-roma):
Aroma pertains to the distinctive fragrance associated with certain plants, including Erythroxylum monogynum. The wood's sandalwood-like aroma suggests potential uses in perfumery and traditional practices, adding another dimension to its value beyond medicinal properties.
25) Tamil:
Tamil refers to the language and cultural identity of the Tamil people, primarily found in Tamil Nadu and parts of neighboring states. The study's focus on local plant species like Erythroxylum monogynum underscores the connection between traditional medicinal practices and the cultural context of the Tamil-speaking population.
26) Nadu:
Nadu, often referring to the land in the native tongue, appears in the context of Tamil Nadu. It emphasizes the regional identity and cultural significance of the area where Erythroxylum monogynum is found, linking local biodiversity with traditional medicinal knowledge and practices.
27) Food:
Food encompasses sustenance derived from various sources, including plants. While the primary focus of the study is on medicinal properties, understanding how the phytochemicals in Erythroxylum monogynum may also contribute to nutritional value underscores the multi-faceted role of such plants in human health.
28) Tree:
The term 'tree' refers to the perennial woody plants from which Erythroxylum monogynum derives. Studying trees provides insight into their ecological role, potential for sustainable harvesting, and contribution to local economies, with emphasis on utilizing tree-based phytochemicals for health benefits.
29) Life:
Life is the condition distinguishing active organisms from lifeless matter, encompassing biological processes. The study of phytochemicals in Erythroxylum monogynum integrates the essence of life by exploring how these natural compounds can enhance human health and contribute to well-being.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Phytochemical screening of Erythroxylum monogynum Roxb.’. Further sources in the context of Science might help you critically compare this page with similair documents:
Medicinal properties, Therapeutic effect, Herbal medicine, Plant material, Qualitative analysis, Phytochemical screening, Quantitative analysis, Secondary metabolite, Alkaloids flavonoids, Bioactive compound, Traditional medicinal plant, Reducing sugar, Medicinal application.