"Chemical constituents and pharmacological effects of Hibiscus rosa-sinensis"
Journal name: World Journal of Pharmaceutical Research
Original article title: Chemical constituents & pharmacological effects of hibiscus rosa- sinensis (china rose) – a review
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Subhashini Shandilya and Vandna Pathak
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Chemical constituents & pharmacological effects of hibiscus rosa- sinensis (china rose) – a review
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr20211-19535
Copyright (license): WJPR: All rights reserved
Summary of article contents:
Introduction
Hibiscus rosa-sinensis, commonly known as China Rose, is a tropical shrub belonging to the Malvaceae family. Recognized for its medicinal properties, various parts of this plant have been traditionally used in several tropical countries to treat a range of ailments, including wounds, inflammation, infections, and gastrointestinal issues. This review highlights the chemical constituents and pharmacological effects of Hibiscus rosa-sinensis, emphasizing its relevance in both traditional medicine and modern research.
Phytochemical Composition
One of the key aspects of Hibiscus rosa-sinensis is its diverse phytochemical profile. Research shows that the plant contains a wide array of compounds, including tannins, flavonoids, alkaloids, saponins, and vitamins such as ascorbic acid and thiamine. Specific compounds, like cyanidin-3,5-diglucoside and quercetin derivatives, are noted for their antioxidant properties. These phytochemicals contribute significantly to the plant's therapeutic potential, marking it as a source of natural antioxidants and other bioactive constituents.
Pharmacological Effects
The pharmacological benefits of Hibiscus rosa-sinensis are manifold. Notably, it exhibits antimicrobial effects, with studies demonstrating its strong antibacterial activity against various pathogens, including Staphylococcus aureus and Salmonella species. Additionally, the extracts of this plant have shown significant antioxidant activity, with the ability to scavenge free radicals, which can help prevent cellular damage and inflammation. This comprehensive array of pharmacological properties underscores the potential of Hibiscus rosa-sinensis in the development of natural therapeutic agents.
Traditional and Medicinal Uses
Traditionally, Hibiscus rosa-sinensis has been utilized in various cultures for its diverse health benefits. In India, for example, it has been used to regulate menstrual cycles, promote lactation, and treat respiratory issues. Other cultures have employed the plant in concoctions for addressing gastrointestinal problems and enhancing hair health. The plant's versatility in traditional remedies reveals its importance in historical health care practices and contemporary herbal therapy.
Conclusion
Hibiscus rosa-sinensis stands out as an impressive example of a medicinal plant with extensive traditional uses and a rich chemical composition. The review highlights its potential therapeutic effects, including antimicrobial, antioxidant, and anti-inflammatory activities, making it a candidate for further exploration in modern medicine. Acknowledging its pharmacological benefits and traditional values can pave the way for more comprehensive studies, ensuring that the knowledge surrounding this remarkable plant continues to evolve and impact future health care practices.
FAQ section (important questions/answers):
What is Hibiscus rosa-sinensis and its common uses?
Hibiscus rosa-sinensis, or China rose, is a tropical shrub known for its medicinal properties, including treating wounds, inflammation, cough, and diabetes, among other ailments.
What are the main pharmacological effects of Hibiscus rosa-sinensis?
The plant possesses antioxidant, antimicrobial, antidiabetic, antiulcer, hepatoprotective, anti-inflammatory, and antifertility properties, making it effective against various diseases.
What are the chemical constituents found in Hibiscus rosa-sinensis?
It contains tannins, flavonoids, alkaloids, saponins, phenolic compounds, and vitamins such as ascorbic acid and thiamine, contributing to its medicinal effects.
What traditional uses does Hibiscus rosa-sinensis have around the world?
In various countries, it's used for menstrual regulation, digestion aid, cough relief, fertility treatment, and even as a remedy for high blood pressure.
How does Hibiscus rosa-sinensis exhibit antioxidant properties?
Studies show that extracts of its leaves and flowers demonstrate strong radical scavenging activity, indicating its potential to protect against oxidative stress.
Are there any documented antidiabetic effects of Hibiscus rosa-sinensis?
Yes, research indicates that extracts can reduce blood glucose levels in diabetic mice, showcasing potential as a natural hypoglycemic agent.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “"Chemical constituents and pharmacological effects of Hibiscus rosa-sinensis"”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Water:
Water is essential for life and plays a crucial role in maintaining physiological functions in both humans and plants. In medicinal plants like Hibiscus rosa-sinensis, water is vital for extracting active compounds during processing. It helps in solubilizing phytochemicals, enhancing the efficacy of traditional herbal remedies.
2) Flavonoid:
Flavonoids are a group of plant metabolites known for their antioxidant and anti-inflammatory properties. In Hibiscus rosa-sinensis, flavonoids contribute to its health benefits by scavenging free radicals and possibly reducing the risk of chronic diseases. They are a key focus in phytochemical studies for their therapeutic potential.
3) Activity:
Activity in this context refers to the biological activities exhibited by the compounds derived from Hibiscus rosa-sinensis. These include antimicrobial, antioxidant, and anti-inflammatory effects, indicating the plant's potential in treating various health conditions. Assessing these activities is critical for understanding the plant’s medicinal value.
4) Cina:
China is geographically significant as the native origin of Hibiscus rosa-sinensis, which is commonly referred to as the 'China Rose.' The country has a rich history of utilizing this plant in traditional medicine, contributing to its cultural and historical relevance in herbal practices and studies.
5) Hair:
Hairs are filamentous projections from the skin that have various roles, including protection and sensory functions. In the context of Hibiscus rosa-sinensis, its use in hair care products highlights its role in enhancing hair texture and growth, reflecting its cosmetic applications.
6) Pharmacological:
Pharmacological refers to the study of the effects of drugs and natural compounds on biological systems. Hibiscus rosa-sinensis exhibits various pharmacological activities, including antidiabetic and anti-inflammatory effects, making it a subject of interest for developing novel therapeutic agents derived from natural sources.
7) Family:
In biological classification, family refers to a group of related plants sharing common characteristics. Hibiscus rosa-sinensis belongs to the Malvaceae family, which encompasses several genera and species known for their diverse medicinal properties, thereby underlining the importance of taxonomical studies in phytochemistry.
8) Blood:
Blood is vital for transporting oxygen and nutrients in the body. The potential effects of Hibiscus rosa-sinensis on blood parameters, such as its blood pressure-lowering and blood sugar-regulating activities, indicate its significance in treating cardiovascular concerns and metabolic diseases, making it an important focus of research.
9) Disease:
Diseases encompass a range of pathological conditions affecting living organisms. The potential of Hibiscus rosa-sinensis in preventing or treating diseases, such as diabetes and hypertension, showcases its role in traditional medicine and the continued exploration of herbal remedies in contemporary healthcare practices.
10) Science (Scientific):
Science is the systematic study of the natural world through observation and experimentation. The examination of Hibiscus rosa-sinensis involves scientific approaches to validate its medicinal claims, exploring its chemical constituents and pharmacological effects through rigorous research methodologies to understand its therapeutic potential.
11) Antibiotic (Antibacterial):
Antibacterial properties refer to the ability to inhibit bacterial growth. Hibiscus rosa-sinensis has shown significant antibacterial activity against various pathogenic bacteria, indicating its potential use in treating infections. This property highlights the importance of exploring natural sources for developing effective antimicrobial agents.
12) Species:
Species is a fundamental category in biological classification indicating groups of organisms capable of interbreeding. Hibiscus rosa-sinensis is a distinct species known for its ornamental and medicinal properties, emphasizing the importance of biodiversity in research and conservation of valuable plant resources.
13) Aureus:
Aureus usually refers to Staphylococcus aureus, a Gram-positive bacterium known for causing various infections. The evaluation of Hibiscus rosa-sinensis against Staphylococcus aureus in antibacterial studies is significant for exploring the plant's therapeutic efficacy and potential role in alternative infection treatments.
14) Phytochemical:
Phytochemicals are bioactive compounds found in plants that contribute to health benefits. In Hibiscus rosa-sinensis, various phytochemicals such as flavonoids, anthocyanins, and alkaloids are studied for their medicinal properties, showcasing the therapeutic potential of plant-based compounds in modern medicine.
15) Inflammation:
Inflammation is a biological response to harmful stimuli and can lead to chronic diseases. The anti-inflammatory properties of Hibiscus rosa-sinensis highlight its potential in alleviating symptoms associated with inflammatory conditions, demonstrating the importance of traditional remedies in treating modern ailments.
16) India:
India has a rich tradition of using Hibiscus rosa-sinensis in Ayurvedic medicine for various ailments. The geographical and cultural context of India emphasizes the plant's relevance in herbal practices and its contribution to the understanding of plant-based treatments in health care.
17) Table:
A table in scientific literature presents data systematically, allowing for easy comparison and reference. Tables summarizing the traditional uses and pharmacological effects of Hibiscus rosa-sinensis aid in synthesizing information for researchers and practitioners interested in medicinal plants.
18) Fever:
Fever is a common symptom indicating infection or illness. The use of Hibiscus rosa-sinensis in traditional medicine for treating fever highlights its significance in herbal therapies, as it is believed to possess antipyretic properties that assist in lowering body temperature during illness.
19) Genu:
Genu refers to the knee region in anatomical terms and does not directly relate to the content on Hibiscus rosa-sinensis. However, understanding anatomical terminology is essential in pharmacology for studying the effects of medicinal plants on bodily structures and functions.
20) Pain:
Pain is a significant clinical symptom requiring effective management. Hibiscus rosa-sinensis has been traditionally used to alleviate pain, showcasing its potential role in alternative therapies for pain relief, highlighting the intersection of ethnobotany and modern medicine in treating symptoms.
21) Accumulation (Accumulating, Accumulate):
Accumulation in a biological context refers to the buildup of substances within organisms. The concept is relevant in studies of Hibiscus rosa-sinensis, particularly in understanding its role in detoxifying agents and evaluating its efficacy in conditions where toxin accumulation leads to disease.
22) Rajasthani:
Rajasthani refers to the cultural context of Rajasthan, India. Herbal traditions, including the use of Hibiscus rosa-sinensis, are important in Rajasthani medicine, reflecting the regional preferences for plants in treating ailments, thereby enhancing the understanding of localized herbal remedies.
23) Evolution:
Evolution refers to the gradual development of organisms over generations. The study of Hibiscus rosa-sinensis within a phylogenetic framework provides insights into its adaptations and relationships to other species, underlining the significance of evolutionary biology in understanding plant diversification.
24) Ayurveda (Ayus-veda):
Ayurveda is an ancient system of medicine from India based on holistic principles. Hibiscus rosa-sinensis plays a role in Ayurvedic practices, where its various parts are used for treating numerous health issues, emphasizing the integration of cultural heritage in understanding medicinal plants.
25) Swelling:
Swelling is a symptom of inflammation and can indicate various medical conditions. The application of Hibiscus rosa-sinensis in traditional medicine to reduce swelling demonstrates its potential topical and internal uses in mitigating inflammatory responses associated with different health disorders.
26) Sanskrit:
Sanskrit is an ancient language of India, significant in traditional medicine texts. The historical context of Sanskrit enhances the understanding of the medicinal uses of Hibiscus rosa-sinensis, where many herbal remedies were documented, reflecting the cultural importance of plant-based medicine.
27) Animal:
Animal refers to living organisms that are not plants. Studies on Hibiscus rosa-sinensis often involve animal testing to provide evidence for its medicinal claims, establishing a bridge between traditional herbal usage and scientific validation of its therapeutic benefits.
28) Cancer:
Cancer is a group of diseases characterized by uncontrolled cell growth. The investigation of Hibiscus rosa-sinensis for its potential anticancer properties highlights its relevance in phytotherapy, aiming to discover natural compounds that could complement conventional cancer treatments.
29) Ulcer:
An ulcer is a sore or wound that can become inflamed or infected. Hibiscus rosa-sinensis has been traditionally used to treat ulcers, emphasizing its relevance in herbal medicine and research aimed at validating its effectiveness in gastrointestinal health.
30) Divya:
Divya is often used as a name in various contexts, potentially referring to individuals involved in scientific research or traditional medicine. Highlighting authors named Divya in the context of Hibiscus rosa-sinensis underscores contributions to phytochemical studies and their findings.
31) Kumar:
Kumar is a common surname in India, often associated with researchers and authors. Mentioning individuals like Kumar in scientific literature indicates the collaborative nature of research efforts focused on studying the pharmacological properties of plants like Hibiscus rosa-sinensis.
32) Ghana:
Ghana is significant in the context of global herbal medicine practices. The traditional uses of Hibiscus rosa-sinensis in Ghana reflect the plant's widespread acceptance in different cultures as a remedy for various ailments, showcasing its global relevance in herbal studies.
33) Kamar:
Kamar is a surname often linked to researchers. Its appearance in studies related to Hibiscus rosa-sinensis indicates contributions to scientific literature, enhancing the credibility of findings related to the plant's pharmacological properties and traditional uses.
34) Sugar:
Sugar is a carbohydrate that serves as an important energy source. The antidiabetic effects of Hibiscus rosa-sinensis show its potential in regulating blood sugar levels, addressing metabolic disorders, and highlighting the relevance of herbal alternatives in managing diabetes.
35) Edema (Oedema):
Edema refers to swelling caused by excess fluid in tissues. The anti-inflammatory properties of Hibiscus rosa-sinensis may contribute to reducing edema, indicating its potential therapeutic role in managing conditions associated with fluid retention and inflammation.
36) Hindi (Himdi):
Hindi is an Indo-Aryan language widely spoken in India. The presence of Hindi in the context of Hibiscus rosa-sinensis highlights the cultural significance of the plant in Indian traditional medicine, where it is known and named in local dialects.
37) Birth:
Birth relates to the origin of life and reproduction. The use of Hibiscus rosa-sinensis for its potential benefits during pregnancy and childbirth reflects traditional practices emphasizing plant-based remedies for supporting reproductive health and maternal care.
38) Labour (Labor):
Labor refers to the process of childbirth. Hibiscus rosa-sinensis has traditional uses as a remedy to facilitate labor, illustrating its application in herbal practices aimed at supporting women during pregnancy, thereby recognizing its role in maternal health.
39) Study (Studying):
Study indicates the systematic investigation of phenomena. Research on Hibiscus rosa-sinensis encompasses a variety of scientific inquiries to validate traditional claims, contributing to the evidence base for its medicinal applications and the understanding of its phytochemical profile.
40) Drug:
Drug refers to any substance used to diagnose, cure, or prevent disease. The exploration of Hibiscus rosa-sinensis for its medicinal properties emphasizes the ongoing quest for natural drugs in herbal medicine, merging traditional knowledge with contemporary scientific inquiry.
41) Tamil:
Tamil is a Dravidian language spoken predominantly in the Indian state of Tamil Nadu. The mention of Tamil in relation to Hibiscus rosa-sinensis reflects the plant's significance in regional herbal medicine practices, demonstrating the cultural richness surrounding its use.
42) Japa:
Japa is the Sanskrit word for Hibiscus rosa-sinensis, highlighting its historical and cultural importance in Indian traditional medicine. This nomenclatural significance showcases the plant's longstanding use in rituals and remedies across various Indian cultures.
43) Raya:
Raya refers to the Malay term associated with Hibiscus. The relationship of plants with different cultural contexts underscores the significance of Hibiscus rosa-sinensis across regions, illustrating its universal appeal and traditional applications in herbal medicine.
44) Bell:
Bell is a term that may reference the shape of Hibiscus flowers. The bell-shaped flower structure is notable for its aesthetic appeal and biological function, attracting pollinators and contributing to the plant's propagation and spread in various habitats.
45) Sour:
Sour refers to a taste sensation, often linked to acidic compounds. Hibiscus rosa-sinensis possesses a sweet-sour flavor profile, making it a favorable choice for teas and beverages, while also highlighting its culinary and nutritional value.
46) Salt (Salty):
Salt is a mineral essential for numerous physiological functions. The role of salt in health intersects with the therapeutic potential of Hibiscus rosa-sinensis, particularly regarding blood pressure regulation and its application in diets aimed at promoting cardiovascular health.
Other Science Concepts:
Discover the significance of concepts within the article: ‘"Chemical constituents and pharmacological effects of Hibiscus rosa-sinensis"’. Further sources in the context of Science might help you critically compare this page with similair documents:
Hibiscus rosa-sinensis, Medicinal compound, Phytochemical analysis, Traditional use, Antioxidant Effect, Botanical Description, Antimicrobial effect, Vernacular name, Antipyretic effect, Cystitis, Antidiabetic effect, Herbal tea, Chemical constituent, Pharmacological effect, Tropical region, Cardiovascular effect, Ornamental plant, Uveitis, Phytochemical compound.