Development and validation of nintedanib esylate RP-HPLC method

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Development and validation of nintedanib esylate RP-HPLC method”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Table:
A table is a systematic arrangement of data, usually in rows and columns, used to present information clearly. In research papers, tables often summarize experimental results, findings, or comparisons and enhance the readability and comprehension of complex information presented in the study.

2) Substance:
Similar to 'substance,' 'substances' denotes multiple kinds of matter or chemical compounds. In the context of pharmaceuticals, it usually pertains to various active pharmaceutical ingredients (APIs) and their impurities. Analyzing multiple substances helps in determining the quality and safety of pharmaceutical products.

3) Water:
Water is a critical solvent in chemical and biological processes. In pharmaceuticals, it's often used for dilutions, extractions, and as a mobile phase in chromatography. Water quality affects the performance of analytical methods and the stability of pharmaceuticals, hence its relevance in research studies.

4) Drug:
Drugs are chemical substances used to diagnose, treat, or prevent diseases. Discovery, development, and analysis of drugs require comprehensive research and clinical testing to ensure their safety and efficacy. The study of drugs encompasses various fields, including pharmacology, toxicology, and clinical medicine.

5) Observation:
Observation refers to the act of monitoring or recording behaviors and outcomes in a study or experiment. In scientific research, precise observations are critical for drawing valid conclusions and making informed decisions. This process can reveal trends and results that inform further scientific inquiries.

6) Relative:
The term 'relative' indicates a comparative perspective or relationship between entities, often concerning measurement or position. In pharmaceutical analysis, 'relative' is frequently used to describe relative response factors, whereby the behavior of one compound is assessed in relation to another during quantification.

7) Quality:
Quality refers to the standard or degree of excellence of a product or service. In pharmaceuticals, quality encompasses aspects like purity, potency, and consistency of a drug. Ensuring high-quality pharmaceuticals is essential for effective treatment and safety in patient care.

8) Disease:
The term 'diseases' is the plural of 'disease' and encompasses various medical conditions that disrupt normal functioning of the body. Recognizing different diseases is essential in developing targeted therapies and preventive measures, guiding research and development within the pharmaceutical industry.

9) Purity:
Purity signifies the absence of impurities in a substance, particularly in pharmaceuticals. High purity of drug substances is crucial to ensure safety and effectiveness. Analytical methods, such as HPLC, are employed to assess the purity of pharmaceutical compounds, ensuring compliance with regulations and standards.

10) Calculation:
Calculation involves the methodical process of determining numerical values from data. In pharmaceutical research, calculations help in quantifying concentrations, doses, yields, and analytical results. Accurate calculations are vital in experimental results interpretation, ensuring valid conclusions are drawn from the data.

11) Performance:
Performance refers to the effectiveness and efficiency of an analytical method or drug in achieving intended outcomes. In the pharmaceutical sector, assessing the performance of a drug or analytical technique involves examining parameters like accuracy, precision, and reliability to ensure they meet specified criteria.

12) Village:
A village is a small settlement, typically rural, often characterized by a close-knit community. In the context of pharmaceutical studies, a village may reference the community used as a study population, influencing social, dietary, and environmental factors that can affect health and treatment outcomes.

13) Channel:
The term 'channel' often refers to a passage or route through which substances or information flows. In pharmaceutical contexts, channels may relate to pathways for drug delivery or methods of communicating research results. Understanding channels is important for ensuring effective treatment delivery.

14) Cancer:
Cancer is a group of diseases characterized by the uncontrolled growth of abnormal cells in the body. Understanding cancer mechanisms is vital for developing drug therapies. Cancer treatment often involves drugs, which researchers study for effectiveness in controlling or eliminating cancer cells.

15) Padra:
Padra is a geographical location, specifically a taluka in Vadodara district, India. The significance of Padra in pharmaceutical research could be its association with local health studies, drug availability, and community-specific disease prevalence, contributing to broader public health initiatives.

16) India:
India is a country in South Asia known for its diverse population and culture. In pharmaceutical research, India is significant for its large market, extensive clinical trials, and growing pharmaceutical manufacturing sector. Research in India often contributes to global drug development and healthcare solutions.

17) Food:
Food refers to any substance consumed for nutritional support. Its role is critical in health and disease considerations, influencing drug pharmacokinetics and pharmacodynamics. Understanding food's interaction with drugs can modify treatment regimens, enhancing patient care and therapeutic outcomes.

18) Line:
In scientific context, 'line' can refer to a line of research or a set of instructions, such as a linear calibration line in analytical methodology. Establishing a precise line relationship aids in understanding data trends and ensuring accuracy in pharmaceutical analysis.

19) Science (Scientific):
Scientific relates to the systematic study of the structure and behavior of the physical and natural world through observation and experiment. Pharmaceutical research relies heavily on scientific principles, including the development of methodologies that ensure drug safety and efficacy.

20) Vomiting:
Vomiting is a common adverse effect of many drugs. Understanding the mechanisms behind drug-induced vomiting is crucial for drug development and patient management. Studies on drug side effects often analyze the incidence of vomiting to evaluate overall treatment safety and tolerability.

21) Liquor:
In a scientific and analytical context, 'liquor' usually refers to a solution resulting from various processes like dissolution or extraction, potentially including alcoholic solutions. Understanding its properties is crucial in formulating reactions in pharmaceutical chemistry, particularly for solvent selection in analysis.

22) Patel:
Patel is a common surname in India, often associated with the Patel community, which is significant in various aspects of society, including business and healthcare. In pharmaceutical research, individuals like Patel may serve critical roles in research teams or companies engaged in drug development.

23) Study (Studying):
A study refers to a detailed examination or analysis of a specific subject or hypothesis. In pharmaceuticals, studies help in understanding drug efficacy, safety, and mechanisms of action. Systematic studies are fundamental for regulatory submissions and advancing medical knowledge.

24) Kaka:
Kaka is a common name or surname in India, often denoting relationship or camaraderie. In the context of pharmaceutical research, individuals named Kaka could be part of project teams or community health initiatives, contributing to the overall research landscape.

25) Tera:
Tera is a unit prefix in the metric system denoting a factor of 10^12 or one trillion. In scientific contexts, it could relate to large-scale measurements or calculations related to drug quantities, aiming for a clear understanding of pharmaceutical data.

26) Sah:
Shah is a common surname in India, often associated with families that have historical prominence or business significance. In pharmaceutical contexts, individuals bearing the surname Shah may hold key positions in companies or research institutions impacting drug development.

27) Pain:
Pain is an unpleasant sensory and emotional experience often associated with actual or potential tissue damage. Understanding pain is essential in developing analgesic drugs. Research on pain management is crucial for improving patient quality of life and effective healthcare delivery.

28) Pur:
The term 'poor' relates to insufficient quality or resources. In social health contexts, poverty can significantly affect access to healthcare and medications. Identifying and addressing the challenges faced by poor populations helps tailor pharmaceutical development towards improved health equity.