Journal name: World Journal of Pharmaceutical Research
Original article title: Antioxidants from natural sources
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Subtitle: review
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Varsha Dhole, Roshni Chaudhari, Sadhana More, Nikita Bhoir and Smita Takarkhede
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Antioxidants from natural sources
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr20214-20079
Copyright (license): WJPR: All rights reserved
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Summary of article contents:
Introduction
Antioxidants are vital compounds that combat oxidative stress in the body by inhibiting oxidation, a chemical process that can lead to the formation of free radicals. These free radicals can cause cellular damage over time, contributing to aging and various degenerative diseases such as heart disease, liver disease, and certain cancers. The body is naturally equipped to manage some free radicals, but excessive exposure due to factors like pollution, stress, and unhealthy lifestyle can overwhelm the body's defenses. This highlights the importance of external sources of antioxidants, particularly those derived from natural foods.
Natural Sources of Antioxidants
One of the primary sources of antioxidants is plant materials, which include fruits, vegetables, herbs, spices, nuts, and seeds. Prominent dietary antioxidants include vitamins A, C, and E, along with minerals such as copper, zinc, and selenium. Among these, natural antioxidants like polyphenols are prevalent, especially in certain herbs and spices, cocoa products, darkly colored berries, and specific vegetables like olives and artichokes. Regular consumption of these foods has been associated with a reduced risk of various chronic diseases, underscoring the health benefits derived from a diet rich in natural antioxidants.
Types and Mechanisms of Antioxidants
Antioxidants can be categorized into three main groups: vitamins, carotenoids, and phenolic compounds. Vitamins C and E are potent antioxidants; Vitamin C is predominantly found in citrus fruits and certain vegetables, while Vitamin E is derived from fat-rich sources such as nuts and seeds. Within the plant kingdom, polyphenols are significant due to their ability to prevent lipid oxidation, contributing to cardiovascular health. Carotenoids, another class of antioxidants, are commonly found in brightly colored vegetables and fruits and are known for their protective effects on eye health. The mechanisms by which antioxidants operate include neutralizing free radicals and preventing the oxidation of low-density lipoproteins (LDL), thus protecting against plaque formation in arteries.
Extraction Methods of Antioxidants
The extraction of antioxidants from plant sources is a critical step for research and application. Various factors influence extraction efficiency, including the type of solvent used, temperature, time, and pH. Common antioxidants, particularly phenolics and flavonoids, are generally soluble in polar solvents, while carotenoids require non-polar solvents. Traditional extraction methods, such as Soxhlet extraction and maceration, can be time-consuming and may degrade sensitive compounds due to prolonged heat. Consequently, non-conventional extraction techniques, such as microwave and ultrasound-assisted extraction, are being explored for their efficiency and ability to preserve thermolabile compounds while reducing the use of organic solvents.
Conclusion
In conclusion, natural antioxidants are essential for maintaining health and preventing oxidative stress-related diseases. This review highlighted important sources of antioxidants, including various fruits, vegetables, nuts, and herbs, along with their respective health benefits and methodologies for extraction. Unlike synthetic antioxidants, natural sources are safer and offer numerous health advantages, reinforcing the importance of integrating antioxidant-rich foods into daily diets for enhanced well-being. Recognizing and promoting these natural sources is pivotal in creating a healthier society.
FAQ section (important questions/answers):
What are antioxidants and why are they important for health?
Antioxidants are compounds that inhibit oxidation, preventing damage to cells caused by free radicals. Over time, excessive free radicals can lead to various diseases, including heart disease and certain cancers. They help neutralize these free radicals, supporting overall health.
What are some natural sources of antioxidants?
Natural sources of antioxidants include fruits, vegetables, herbs, spices, nuts, and seeds. Common examples are berries, citrus fruits, dark leafy greens, and legumes, which are rich in important antioxidants like vitamins A, C, E, and various polyphenols.
How do antioxidants benefit the human body?
Antioxidants help protect the body by neutralizing free radicals, reducing oxidative stress, and preventing cellular damage. This protection may lower the risk of chronic diseases such as heart disease, diabetes, and certain types of cancer.
What extraction methods are commonly used for antioxidants?
Extraction methods vary and can include conventional methods like Soxhlet extraction and maceration, or non-conventional methods like ultrasound and microwave extraction. The choice of method depends on the type of antioxidant and desired efficiency.
What types of antioxidants are found in fruits and vegetables?
Fruits and vegetables contain various antioxidants, including vitamins, carotenoids, and phenolic compounds. For instance, vitamin C is abundant in citrus fruits, while carotenoids are found in orange and yellow vegetables like carrots and sweet potatoes.
Why are natural antioxidants preferred over synthetic ones?
Natural antioxidants are generally considered safer and healthier compared to synthetic alternatives. They are extracted from plant sources and can provide additional health benefits beyond antioxidant activity, while synthetic antioxidants may have adverse effects.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Antioxidants from natural sources”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Disease:
Diseases encompass a wide range of health conditions that disrupt normal bodily functions. Pursuing a diet high in natural antioxidants from sources such as fruits and vegetables can mitigate the risk of diseases, particularly those associated with oxidative stress, highlighting the importance of prevention through dietary choices.
2) Cancer:
Cancer is a group of diseases characterized by uncontrolled cell growth and division, which can spread to other body parts. The connection between antioxidants and cancer prevention is significant, as antioxidants can neutralize free radicals that contribute to DNA damage and tumor formation, providing a protective role against this serious illness.
3) Food:
Food plays a critical role in human health, providing essential nutrients necessary for bodily functions. Antioxidants found in food help to neutralize free radicals, thereby protecting against oxidative stress which is linked to chronic conditions such as heart disease, diabetes, and cancer, emphasizing the importance of a balanced diet rich in antioxidants.
4) Inflammation:
Inflammation is the body's response to injury or infection, characterized by redness, heat, swelling, and pain. Chronic inflammation is linked to various diseases, and the consumption of antioxidants may help reduce inflammation through their ability to neutralize free radicals, thereby preventing cellular damage and promoting overall health.
5) Nature:
Nature refers to the natural environment, which is a source of numerous health-promoting substances, including antioxidants from plants. Utilizing natural sources for antioxidants is increasingly relevant due to concerns regarding synthetic additives. Exploring natural compounds can yield effective alternatives for health benefits and disease prevention.
6) Water:
Water is a vital component for all living organisms, facilitating numerous biochemical processes. In the context of antioxidants, water is often used as a solvent for extracting hydrosoluble antioxidants from plant materials, thus playing a critical role in preserving the quality and efficacy of antioxidant compounds.
7) Diet:
Diet refers to the types and amounts of food consumed by individuals. A diet rich in antioxidants, derived from various fruits, vegetables, and whole foods, is essential for combating oxidative stress, reducing inflammation, and lowering the risk of degenerative diseases, thereby contributing to overall health and longevity.
8) Blood:
Blood is a vital fluid that circulates throughout the body, transporting nutrients and oxygen to tissues while removing waste products. Antioxidants in food can be absorbed into the bloodstream, providing systemic benefits and helping to protect cells from oxidative damage, thus playing a role in overall health maintenance.
9) Rich (Rch):
Rich denotes a high concentration or abundance of a particular quality. In the context of antioxidants, foods rich in these compounds, such as berries, nuts, and leafy greens, offer greater health benefits. Consuming a rich variety of these foods enhances antioxidant intake, supporting disease prevention and overall well-being.
10) Human body:
The human body is a complex system made up of numerous cells, tissues, and organs that interact to sustain life. Antioxidants are crucial for protecting the human body from oxidative damage caused by free radicals, thus playing a significant role in maintaining health and preventing various diseases.
11) Knowledge:
Knowledge refers to understanding gained through experience or education. In the context of health, knowledge about antioxidants, their sources, and their health benefits is vital for making informed dietary choices that can prevent diseases and promote longevity, emphasizing the importance of research and education in nutrition.
12) Flavonoid:
Flavonoids are a group of phytochemicals known for their antioxidant properties, commonly found in fruits, vegetables, and beverages like tea. These compounds help protect against oxidative stress and inflammation, contributing to the prevention of chronic diseases and promoting overall health through their multiple health benefits.
13) Varsha (Varsa):
Varsha Dhole is the lead author of the research paper under review, focusing on the role of natural antioxidants from plant sources. Her insights and expertise contribute to the understanding of how these antioxidants can offer health benefits and their relevance in preventing oxidative stress-related diseases.
14) Sugar:
Sugar is a simple carbohydrate that serves as an energy source for the body. However, excessive sugar consumption can lead to health issues, including weight gain and metabolic disorders. In the context of antioxidants, high sugar content in certain foods can inhibit the absorption of beneficial compounds, emphasizing dietary balance.
15) Lemon:
Lemon is a citrus fruit rich in vitamin C, a powerful antioxidant. The consumption of lemons can support the body's antioxidant defenses and overall health. Lemons are commonly recommended for their beneficial effects on the immune system and for their role in reducing the risk of chronic diseases.
16) Beta:
Beta refers to beta carotene, a carotenoid found abundantly in fruits and vegetables, particularly those that are orange and yellow. Beta carotene is known for its antioxidant properties and is converted into vitamin A in the body, contributing to eye health and immune function.
17) Phytochemical:
Phytochemicals are bioactive compounds found in plants that contribute to their color, flavor, and disease resistance. Many phytochemicals, including flavonoids and polyphenols, possess antioxidant properties that can help protect the body from oxidative stress and reduce the risk of chronic diseases.
18) Study (Studying):
Study involves systematic investigation and analysis to learn more about a specific topic. The ongoing study of natural antioxidants investigates their sources, effectiveness, extraction methods, and health benefits, aiming to promote awareness of healthy dietary choices and support disease prevention strategies in the population.
19) Mineral:
Mineral, as an abstract concept, refers to essential nutrients required by the body that cannot be synthesized internally and must be obtained through diet. In terms of antioxidants, certain minerals such as magnesium and zinc play significant roles in enzymatic antioxidant defense systems, supporting overall health.
20) Sadhana:
Sadhana More is one of the co-authors of the research paper focused on natural antioxidants. Her contributions to the study help enhance the understanding of plant-based antioxidants and their benefits, underscoring the teamwork involved in scientific research and the pooling of expertise to address health issues.
21) Quality:
Quality refers to the standard of something, which in this context relates to the efficacy of antioxidants extracted from natural sources. The quality of antioxidants is influenced by their extraction methods and the bioavailability of these compounds, impacting their potential health benefits and overall effectiveness.
22) Heating:
Heating is a method used in various food processing techniques, which can affect the stability and efficacy of nutrient compounds, including antioxidants. Excessive heating can degrade antioxidant properties, making it necessary to explore optimal extraction techniques that maintain their health benefits.
23) Species:
Species refer to distinct biological classifications of living organisms. In the context of antioxidants, identifying various plant species that are rich in these compounds is crucial for research and application in nutrition. Different species may offer unique antioxidant profiles and health benefits, promoting biodiversity in dietary sources.
24) Family:
Family can refer to groups of related plants, animals, or individuals. In botanical terms, plant families can contain various species that share common characteristics. Understanding plant families helps in researching natural antioxidants, providing insights into their potential health benefits based on their shared phylogenetic traits.
25) Medium:
Medium refers to the substances or environment through which something is transferred or absorbed. In the context of extraction processes, the choice of medium (solvents like water, ethanol) plays a critical role in the yield and effectiveness of antioxidant extraction from plants, directly influencing the study of these compounds.
26) Smita:
Smita Takarkhede is another co-author of the research study on antioxidants. Her work contributes significantly to the exploration of natural sources of antioxidants, playing a key role in advancing knowledge about the health benefits of these compounds and their potential role in disease prevention.
27) Table:
Table refers to a structured arrangement of data, often used in research to summarize findings. In scientific literature, a table listing antioxidant sources, their compounds, and health benefits provides a clear overview and facilitates comparison, enhancing readers' understanding of the nutritional value of various foods.
28) Field:
Field denotes an area of study or professional practice. In scientific research, studying the field of natural antioxidants is crucial for developing effective health interventions and dietary strategies aimed at mitigating the risk of diseases linked to oxidative stress and improving public health outcomes.
29) Fight:
Fight refers to the act of combating or opposing something harmful. In the context of health, antioxidants are known to fight oxidative stress and inflammation by neutralizing free radicals, effectively protecting cells from damage and reducing the risk of chronic diseases linked to these harmful processes.
30) Oil:
Oils are fats that are liquid at room temperature and are used in cooking and food preparation. Certain oils, particularly those rich in antioxidants (e.g., olive oil), can contribute to a healthy diet by providing essential fatty acids and protective compounds that help combat oxidative stress in the body.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Antioxidants from natural sources’. Further sources in the context of Science might help you critically compare this page with similair documents:
Medicinal plant, Flavonoid, Chronic disease, Chemical reaction, Geographical distribution, Lipid peroxidation, Vitamin C, Polyphenols, Extraction method, Free Radical, Food products, Vitamin E, Natural antioxidant, Carotenoid, Oxidation reaction, Synthetic antioxidant.