Journal name: World Journal of Pharmaceutical Research
Original article title: Pharmaceutical study on gandhak druti
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Dr. Aabha Pandey, Dr. Gopi Krishna Maddikera and Dr. Shashidhar Jeeru
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Pharmaceutical study on gandhak druti
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr20214-20056
Copyright (license): WJPR: All rights reserved
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Summary of article contents:
Introduction
The article discusses the formulation known as Gandhak Druti, a crucial aspect of Rasashastra, which is a branch of Ayurveda focusing on the transformation of minerals and metals into medicinal forms. Druti Kalpana refers to the process that ensures that dense materials remain in a molten or liquefied state, making them therapeutically absorbable. Gandhak Druti, derived from the mineral sulphur (gandhak), is noted for its efficacy in treating various skin disorders and improving appetite, and is often utilized by Ayurvedic practitioners for a range of conditions.
The Concept of Druti Kalpana
Druti, in Ayurvedic texts, denotes a method that facilitates the maintenance of hard and dense materials in a liquefied form. According to ancient texts, the characteristics of Druti include being non-sticky, uniformly liquefied, lustrous, lighter in weight compared to its original form, and compatible with mercury. The preparation of Druti plays a pivotal role in Ayurveda, ensuring that herbal ingredients and minerals are created in a consumable form that maximizes therapeutic benefits. Adhering to specific traditional guidelines, the process of Druti preparation transforms sulphur into a stable liquid state, known as Gandhak Druti.
Ingredients and Preparation of Gandhak Druti
Gandhak Druti comprises a combination of one mineral and several herbal ingredients, including shuddha gandhak (sulphur), shunti (ginger), maricha (black pepper), pippali (long pepper), and tila taila (sesame oil). The preparation involves a detailed process that consists of blending these ingredients and employing a traditional method that utilizes heat and specific techniques to create the final product. A noted method described in classical texts involves rolling a mixture of powdered ingredients in a silk cloth, immersing it in oil, and igniting it to collect the resultant oil. This method enhances its therapeutic potency, making Gandhak Druti effective for various ailments.
Therapeutic Benefits
Gandhak Druti is reputed for its capabilities in enhancing appetite and is clinically indicated for various health conditions such as ksaya roga (tuberculosis), pandu roga (anemia), kasa (cough), swasa (asthma), sula (pain), grahani roga (dysentery), and ama dosa (toxicity). The medicinal properties are attributed to its constituent parts, which offer a holistic approach to treating these conditions by providing relief and promoting overall wellness. It is often consumed daily alongside other Ayurvedic preparations to maximize its benefits, showcasing its significance in traditional medicine.
Conclusion
The exploration of Gandhak Druti affirms its uniqueness as a formulation that transcends the mere liquefaction of minerals. It embodies a sophisticated understanding of Ayurvedic pharmaceutical procedures, demonstrating how traditional methods can yield beneficial therapeutic formulations. This study underscores Gandhak Druti’s importance in Ayurveda, not only in treating specific ailments but also in enhancing overall vitality and well-being. The practices derived from Rasashastra present a blend of scientific wisdom and herbal knowledge, essential for the advancement of holistic health solutions.
FAQ section (important questions/answers):
What is Gandhak Druti and its purpose in Ayurveda?
Gandhak Druti is an Ayurvedic herbomineral formulation. It is primarily indicated for managing conditions like ksaya roga, pandu roga, kasa, swasa, and ama dosa, enhancing appetite and providing lightness to the body.
What does the term 'Druti' refer to in Rasashastra?
'Druti' refers to the process of maintaining metals or minerals in a molten state. It involves various pharmaceutical techniques to make these substances therapeutically absorbable and palatable.
What are the main ingredients used in Gandhak Druti?
The main ingredients include Shuddha Gandhak (sulphur), Shunti (Ginger), Pippali (Piper longum), Maricha (Piper nigrum), and Tila taila (sesame oil), combining one mineral and four herbal drugs.
How is Gandhak Druti prepared according to Ayurveda?
Gandhak Druti is prepared by mixing Shuddha Gandhak and trikatu, wrapping it in a silk cloth, immersing in Tila taila, and igniting one end to collect the oil that drips down.
What are the therapeutic benefits of using Gandhak Druti?
Gandhak Druti is known to improve appetite, alleviate symptoms of various disorders like ksaya roga and pandu roga, and provide lightness to the body, enhancing overall vitality.
What are the characteristics of Druti as outlined in the texts?
Druti has five characteristics: it should be non-sticky, liquified, lustrous, lighter than its original weight, and should mix readily with mercury, ensuring effective therapeutic properties.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Pharmaceutical study on gandhak druti”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Druti:
Druti refers to the pharmaceutical process in Ayurveda that transforms solid minerals and metals into a stable, liquefied state suitable for therapeutic use. It denotes a specific preparation method where substances maintain their molten form, allowing for enhanced absorption and efficacy in medicinal applications.
2) Roga:
Roga translates to 'disease' or 'disorder' in Ayurveda. It encompasses a wide range of pathological conditions that impact health. Understanding roga is essential for diagnosing and treating ailments using Ayurvedic principles, guiding practitioners in selecting appropriate therapies and formulations tailored to individual needs.
3) Drug:
Drugs in Ayurveda refer to the combination of active therapeutic ingredients that provide health benefits. These substances can be herbal, mineral, or animal-based and are formulated through various kalpanas to enhance their properties, ensuring optimum efficacy while maintaining safety in medical applications.
4) Kalpana:
Kalpanas refer to the various formulations and preparation techniques employed in Ayurveda. These processes are fundamental for creating effective herbal and mineral medicines, underscoring the creativity and knowledge inherent in traditional healing practices.
5) Ayurveda (Ayus-veda):
Ayurveda is a traditional Indian system of medicine that emphasizes balance in the body, mind, and spirit for optimal health. It employs natural therapies, including herbal medicines, dietary practices, and lifestyle modifications, focusing on prevention and holistic treatment of health conditions.
6) Gandhaka (Gamdhaka):
Gandhaka, or sulfur, is a key mineral used in Ayurvedic formulations, prized for its therapeutic properties. Primarily employed in treatments for skin disorders and digestive issues, it is processed through specific techniques, such as Druti, to enhance its bioavailability and therapeutic efficacy.
7) Varanasi (Varanashi):
Varanasi is a historic city in India, known for its rich cultural heritage and significance in Ayurveda. It serves as a hub for traditional knowledge and practices, housing numerous Ayurvedic colleges and institutions that contribute to the education and promotion of ancient healing arts.
8) Mineral:
Minerals are inorganic substances vital for bodily functions and health. In Ayurveda, minerals are processed through specific methods to enhance their therapeutic properties, ensuring they are effective and safe to use in treatments for various health conditions.
9) Taila (Thaila):
Taila refers to oil in Ayurveda, a critical component in many therapeutic preparations, including massages and medicated formulations. Oils serve as carriers for active ingredients, enhancing absorption and efficacy while also providing nourishment and hydration to the skin.
10) Ushna (Usna):
Ushna translates to 'hot' in Ayurveda, referring to the quality of certain substances or processes. It is believed to possess detoxifying, stimulating, and energizing properties. Ushna is crucial for balancing doshas and treating conditions associated with excess coldness in the body.
11) Katu:
Katu means 'pungent' or 'sharp' in Ayurveda, describing the taste and qualities of certain herbs and substances. It is known to stimulate digestion, enhance appetite, and clear congestion, making it an essential consideration in formulating treatments for various disorders.
12) Rasashastra (Rasa-shastra, Rasasastra):
Rasa-shastra is the Ayurvedic branch focused on the preparation of medicines from metals and minerals. It involves the study of alchemical processes relevant to creating therapeutic formulations, often emphasizing the transformation of basic elements into potent treatments for various health conditions.
13) Kshayaroga (Ksayaroga, Kshaya-roga):
Ksaya-roga refers to 'wasting diseases' in Ayurveda, characterized by significant loss of body mass and vitality. Conditions like tuberculosis or chronic infections fall under this category, necessitating specific therapeutic interventions that enhance nourishment and vitality through appropriate herbal formulations.
14) Tilataila (Tila-taila):
Tila-taila, or sesame oil, is an important oil in Ayurveda valued for its nourishing and therapeutic properties. Rich in essential fatty acids and antioxidants, it is often used in formulations for massage, skin care, and as a base for various herbal preparations.
15) Karnataka:
Karnataka is a state in India known for its rich heritage in Ayurveda. It hosts numerous Ayurvedic institutions and practitioners, playing a pivotal role in the preservation, practice, and promotion of traditional healing methodologies alongside modern healthcare practices.
16) Amadosha (Amadosa, Ama-dosha):
Ama-dosa represents an Ayurvedic concept referring to 'toxic metabolic waste' produced from improperly digested food. It is thought to contribute to various health disorders. Treating ama-dosa involves detoxification strategies and enhancing digestive functions to restore balance.
17) Medicine:
Medicine encompasses the science and practice of diagnosing, treating, and preventing diseases. In Ayurveda, it focuses on natural remedies, emphasizing holistic approaches tailored to individual needs, synthesizing herbs, minerals, and lifestyle modifications to promote health and well-being.
18) Madhura:
Madhura means 'sweet' in Ayurveda, representing one of the six tastes. Sweetness is considered nourishing and calming, having a balancing effect on Vata and Pitta doshas. It is integral in formulating medicines, often enhancing palatability and therapeutic benefits.
19) Kshaya (Ksaya):
Ksaya signifies 'wasting' or 'depletion' in Ayurveda, referring to conditions leading to loss of strength, health, and vitality. Addressing ksaya involves using specific treatments aimed at restoring balance and promoting nourishment to combat the effects of disease.
20) Table:
Table refers to a structured representation of data or information. In the context of Ayurveda, it is often utilized to present medicinal formulations, ingredient proportions, and their properties in a clear and concise manner, facilitating understanding and application in therapeutic practices.
21) Tila:
Tila, or sesame, refers to the sesame seed plant used for its nutritious seeds and oil in Ayurveda. It is known for its health benefits, including supporting skin health, digestion, and providing energy, making it a key ingredient in various Ayurvedic formulations.
22) Dosha (Dosa):
Dosa in Ayurveda denotes a pathological condition or imbalance within the body's systems, impacting health. Understanding dosas is fundamental to Ayurvedic diagnosis and treatment, guiding practitioners in crafting specific interventions to restore balance and harmony.
23) Kasa (Kasha):
Kasa refers to a cough or respiratory disorder in Ayurveda. It is characterized by irritation in the respiratory tract. Treatment often focuses on soothing the airways, improving digestion, and enhancing overall respiratory health through specific herbal formulations and lifestyle adjustments.
24) Sharman (Sarma, Sharma, Sarman):
Sharma is a common surname in India, often associated with scholars and practitioners in various fields, including Ayurveda. Its inclusion in Ayurvedic literature often denotes respect for the contributions made to the understanding and practice of traditional medicine.
25) Pandita (Pandit):
Pandit is a title signifying an expert or learned individual in a specific field, especially in Indian traditions. In Ayurveda, it indicates a scholar well-versed in ancient texts and practices, contributing significantly to the knowledge and dissemination of Ayurvedic medicine.
26) Laghu:
Laghu translates to 'light' or 'easy to digest' in Ayurveda. It is an important quality when assessing food and medicines, indicating substances that are beneficial for digestive health, particularly in treating imbalances associated with heaviness or sluggishness in the body.
27) Ratna:
Ratna means 'gem' or 'precious' in Sanskrit, often used symbolically in Ayurveda to denote valuable herbs, minerals, or formulations that possess significant therapeutic properties. Ratna serves as a marker for quality and efficacy in Ayurvedic drugs and treatments.
28) Dhatu:
Dhatus refers to the fundamental tissues in the body essential for health and vitality. Understanding dhatus is vital in Ayurveda when diagnosing ailments and designing therapies, as they influence physiological functions and the overall well-being of individuals.
29) Shula (Sula):
Shula denotes pain or discomfort, often used in Ayurvedic contexts to describe specific ailments requiring attention. Identifying the source and type of shula is essential for determining effective treatments that aim to relieve pain and restore overall balance.
30) Shuddhagandhaka (Suddhagandhaka, Shuddha-gandhaka):
Suddha-gandhaka, or purified sulfur, is crucial in Ayurvedic formulations, ensuring that it is free from impurities and is both safe and effective. Its use in traditional medicine focuses on benefiting skin health and improving digestive functions, affirming its therapeutic significance.
31) Container:
Container refers to any vessel used for holding medicinal preparations in Ayurveda. The selection of appropriate containers is crucial for preserving the quality and integrity of herbal and mineral formulations, ensuring their effectiveness and safety for therapeutic use.
32) Rasayana (Rasa-ayana):
Rasayana is an Ayurvedic concept focused on rejuvenation and longevity. It encompasses therapies designed to promote vitality, enhance mental clarity, and improve overall health. Rasayana emphasizes nurturing the body and mind for optimal functioning throughout life, often incorporating specific herbs and practices.
33) Shastra (Sastra):
Shastra means 'scripture' or 'treatise' in Sanskrit, often referring to authoritative texts in Ayurveda that elucidate principles, practices, and medicinal formulations. Shastras serve as foundational references for practitioners, guiding them in the application of traditional healing arts.
34) Pippali (Pippalin):
Pippali, or long pepper, is an important medicinal herb in Ayurveda known for its warming properties. It is utilized in formulations for enhancing digestion, respiratory health, and overall vitality. Pippali is an integral component in many Ayurvedic treatments due to its potent therapeutic effects.
35) Shunthi (Sunthi, Sumthi, Shumthi):
Shunthi, or ginger, is a widely used herb in Ayurveda prized for its anti-inflammatory and digestive properties. It enhances appetite, alleviates nausea, and supports overall gastrointestinal health. Its incorporation into remedies makes it one of Ayurveda's fundamental healing agents.
36) Shuddha (Suddha):
Suddha, similar to 'shuddha,' denotes purity, highlighting the essential nature of cleansing and refining ingredients in Ayurveda. Ensuring purity is foundational to creating safe and effective therapeutic formulations, making it a critical consideration in Ayurvedic practice and preparation methods.
37) Mishra (Misra):
Mishra is a common surname in India, often associated with scholars and experts in various fields, including Ayurvedic medicine. It signifies a learned individual whose contributions enrich the practice and understanding of traditional healing systems within the broader context of Indian knowledge.
38) Kapha:
Kapha is one of the three doshas in Ayurveda, representing the elements of earth and water. It embodies qualities of stability, thickness, and moisture. Balancing kapha is crucial for maintaining health, and its imbalance can lead to various physical and psychological disorders.
39) Varti (Vartin):
Varti refers to a cylindrical roll or wick used in certain Ayurvedic preparations. It is typically employed in processes that involve heating or delivering medicinal substances, playing an essential role in the methodology for preparing specific formulations.
40) Study (Studying):
Study in the Ayurvedic context involves the rigorous examination and exploration of ancient texts, principles, and practices. It emphasizes gaining knowledge for the purpose of applying traditional wisdom to enhance healthcare practices, bridging ancient wisdom with modern understanding.
41) Hara:
Hara means 'destroyer' in Sanskrit, used frequently to denote elements that alleviate or remove ailments. Incorporating hara in formulations indicates the focus on healing and restoring balance by addressing the root causes of health issues effectively.
42) Rasa (Rasha):
Rasa signifies 'taste' or 'essence' in Ayurveda, representing the sensory qualities of food and medicines. Understanding rasa is fundamental to formulating treatments, as different tastes influence bodily functions and contribute to therapeutic effects, guiding practitioners in creating balanced dietary and medicinal remedies.
43) Vata:
Vata is one of the three doshas in Ayurveda, representing space and air qualities such as movement and creativity. Maintaining vata balance is critical for overall health, as its imbalance can lead to various disorders affecting physical, emotional, and mental well-being.
44) Piper longum:
Piper longum, known as long pepper, is a significant herb in Ayurveda valued for its medicinal properties. It aids digestion, enhances respiratory health, and promotes wellness by stimulating appetite and overall vitality, emphasizing its importance in many traditional formulations.
45) Betel leaf:
Betel leaf is a popular herb in Ayurveda, often used for its therapeutic qualities, particularly in digestive health. It is commonly incorporated into treatments for enhancing oral hygiene and as a digestive aid, highlighting its versatility in traditional medicine.
46) Shuddhaparada (Suddhaparada, Shuddha-parada):
Suddha-parada, or purified mercury, is utilized in Ayurveda for its unique properties in formulations. Purification processes enhance its safety for therapeutic use in specific contexts, highlighting its role in creating powerful Ayurvedic medicines according to traditional principles.
47) Bhaishajya (Bhaisajya):
Bhaishajya refers to 'medicinal substance' in Ayurveda, encompassing a wide range of therapies and formulations aimed at treatment and prevention of diseases. It is central to Ayurvedic practice, guiding the systematic application of herbs, minerals, and dietary practices for optimal health.
48) Visodhana (Vishodhana):
Vishodhana signifies the process of purification in Ayurveda. This term is often associated with methods that cleanse toxic substances from herbs and minerals before their therapeutic use, ensuring that medicines are safe and reliable for treating various ailments.
49) Kaphavata (Kapha-vata):
Kapha-vata refers to the combination of two doshas, emphasizing a balanced approach in Ayurveda. Understanding their interplay is crucial for diagnosing health conditions and tailoring treatments, as imbalances in kapha and vata can lead to physical and emotional disturbances.
50) Discussion:
Discussion in Ayurvedic context involves analyzing and interpreting therapeutic concepts, formulations, and methodologies. It facilitates the exchange of ideas among practitioners, enhancing understanding and enabling the integration of traditional knowledge with contemporary health practices.
51) Nagavalli (Naga-valli):
Nagavalli, or betel leaf, is a significant plant in Ayurveda known for its therapeutic and cultural uses. It is often employed in digestion aids and enhances oral health, showcasing its importance in traditional medicine and culinary practices.
52) Vatahara (Vata-ahara):
Vata-hara signifies substances that pacify the Vata dosha. These herbs and formulations are vital in Ayurveda for restoring balance when Vata becomes excessive, addressing conditions characterized by dryness, pain, and instability, hence reaffirming the holistic approach of Ayurvedic therapies.
53) Shodhana (Sodhana):
Shodhana indicates the purification process in Ayurveda, critical for enhancing the safety and efficacy of herbal and mineral substances. This methodology ensures that toxic elements are removed from preparations, rendering them suitable for therapeutic application and promoting better health.
54) Prabhava:
Prabhava translates to 'influence' or 'effect' in Ayurveda, denoting the inherent properties of herbs or substances that contribute to their therapeutic outcomes. Recognizing prabhava is essential in formulating and utilizing herbal medicines to achieve desired health benefits.
55) Lakshana (Laksana):
Lakshana means 'characteristics' or 'symptoms' in Ayurveda. It describes the unique properties of substances or conditions, aiding practitioners in diagnosis and treatment by providing a clear understanding of how various treatments influence health and wellness balance.
56) Mandagni (Manda-agni, Mamdagni):
Mandagni refers to impaired digestive fire in Ayurveda, often leading to weak digestion and accumulation of ama. Correcting mandagni is essential for promoting health, as it influences metabolism, nutrient absorption, and overall vitality through specific dietary and medicinal interventions.
57) Rasendra (Rasa-indra):
Rasendra signifies an esteemed individual specializing in rasashastra, particularly in Ayurvedic alchemy regarding minerals and their transformative processes. This figure plays a critical role in preserving traditional knowledge and practices vital for the development of effective remedies in Ayurvedic medicine.
58) Saṃdaṃśa (Samdamsa, Samdamsha, Sandamsa):
Sandamsa is used to refer to a specific device or apparatus in Ayurveda essential for medicinal preparation processes. It is often employed to facilitate the meticulous manipulation and handling of medicines during heating or transformation, ensuring precision and effectiveness.
59) Sanskrit:
Sanskrit is the ancient language of India in which many Ayurvedic texts are written. Its precise terminology and structure are crucial for accurately conveying complex concepts and practices in Ayurveda, contributing to the preservation and dissemination of traditional knowledge.
60) Laghuta:
Laghuta, meaning 'lightness,' is an essential concept in Ayurveda, emphasizing the importance of consuming and utilizing easily digestible substances. It plays a significant role in maintaining digestive health and overall well-being, particularly during treatments for excess heaviness.
61) Visarpa:
Visarpa translates to 'skin diseases' in Ayurveda, denoting a range of inflammatory conditions. Understanding visarpa is critical in Ayurvedic practice, as targeted treatments and formulations aim to alleviate symptoms, address underlying imbalances, and promote skin health.
62) Parpati:
Parpati refers to a specific type of formulation in rasashastra characterized by its alchemical preparation process. It involves combining herbs and minerals to create potent therapeutic agents that harness the benefits of both plant and mineral-based medicines.
63) Grahani:
Grahani signifies a condition related to digestive disorders or malabsorption in Ayurveda. Treatments for grahani focus on restoring digestive health and function through specific dietary practices and herbal formulations, reaffirming the importance of digestion in overall well-being.
64) Pottali:
Pottali refers to a specific type of Ayurvedic preparation or container, often used for encapsulating herbs and minerals. It plays an essential role in therapeutic applications, emphasizing the creative and systematic approach to Ayurvedic formulations and the importance of proper containment.
65) Trikatu (Tri-katu):
Trikatu is a traditional Ayurvedic formulation consisting of three pungent herbs: ginger, black pepper, and long pepper. It is utilized for improving digestion and metabolism, highlighting the synergy of these spices in enhancing overall health and vitality.
66) Snigdha:
Snigdha translates to 'unctuous' or 'oily' in Ayurveda, indicating the quality of certain substances that nourish and hydrate. Understanding snigdha is critical for formulating oils and creams as well as for determining dietary choices essential for maintaining health and balance.
67) Krishna (Krsna):
Krishna, in Ayurvedic literature, often signifies specific indigenous plants known for their therapeutic properties. Understanding Krishna plants and their uses helps integrate traditional knowledge into modern healthcare practices, enhancing the effectiveness of herbal treatments.
68) Kushtha (Kustha):
Kushtha refers to skin diseases or leprosy in Ayurveda. It encompasses a range of dermatological conditions requiring targeted treatments to promote healing, emphasizing the significance of herbal and mineral formulations in addressing complex skin disorders.
69) Prahara:
Praharas refer to a specific unit of time in Ayurveda, typically equivalent to three hours. This concept is often utilized in Ayurvedic treatments and preparations, designating optimal durations for certain processes like ingestion or therapeutic interventions.
70) Tikshna (Tiksna):
Tikshna translates to 'sharp' or 'intense' in Ayurveda, describing the qualities of certain herbs or substances. Tikshna properties are utilized for their effectiveness in stimulating digestion and metabolism while addressing imbalances, enhancing therapeutic efficacy.
71) Kashaya (Kasaya):
Kashaya means 'astringent' in Ayurveda, one of the six tastes. It is known for its purifying qualities and is often used in formulations to mitigate excess moisture or heat, playing a role in balancing various doshas.
72) Burning (Burn, Burned, Burnt):
Burning refers to a crucial process in Ayurvedic medicine involving the application of heat in preparation methods, essential for enhancing the properties of herbal and mineral substances, ensuring their therapeutic potential is maximized in treatment formulations.
73) Surface:
Surface refers to the area on which Ayurvedic preparations are made or applied. In preparing medicines, ensuring a clean and suitable surface is vital to maintaining the integrity of ingredients and their final formulations, which impacts effectiveness.
74) Dravya:
Dravya refers broadly to any substance used in therapy, encapsulating the core materials involved in Ayurvedic practices, including herbs, minerals, and formulations. The diverse applications of dravyas underline the holistic approach of Ayurveda toward health and balance.
75) Yantra (Yamtra):
Yantra signifies a tool or instrument used in Ayurvedic practices, particularly in preparation processes. It emphasizes the importance of precise instruments in administering treatments and crafting formulations, reinforcing the methodology inherent in traditional healing.
[Note: The above list is limited to 75. Total glossary definitions available: 99]
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