Snuhi (euphorbia nerifolia linn.) upavisha – a review

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Journal name: World Journal of Pharmaceutical Research
Original article title: Snuhi (euphorbia nerifolia linn.) upavisha – a review
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Author:

Dr. Ravindra Anirudha Mirgane


World Journal of Pharmaceutical Research:

(An ISO 9001:2015 Certified International Journal)

Full text available for: Snuhi (euphorbia nerifolia linn.) upavisha – a review

Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research

Doi: 10.20959/wjpr202110-21253

Copyright (license): WJPR: All rights reserved


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Summary of article contents:

Introduction

Ayurveda, foundational to Indian medical science, emphasizes the utilization of various parts of medicinal plants to treat ailments. Among these plants is Euphorbia nerifolia, commonly known as Snuhi, which is categorized as an upavisha, or less toxic plant. This classification acknowledges its potential to produce toxic symptoms while still offering therapeutic benefits when administered correctly. The writings of ancient Ayurvedic scholars underscore the critical importance of appropriate dosage and administration methods to prevent adverse effects.

The Concept of Upavisha

Snuhi falls under the category of upavisha, which refers to substances that have mild toxic properties but can be beneficial in healing when used properly. The ancient texts, including Charaka Samhita, highlight that strong poisons can become effective medicines following proper purification, or shodhana. This idea is critical in Ayurvedic practice, emphasizing the transformative potential of certain substances based on how they are handled. Snuhi’s milky latex is noted for its drastic purgative effects and is significant in various traditional preparations.

Therapeutic Uses in Ayurveda

Snuhi exhibits a wide range of therapeutic applications, including its use in treating conditions like vatavyadhi (nervous disorders), gulma (abdominal lumps), udara (abdominal diseases), and arsha (hemorrhoids). The latex and various parts of the plant are utilized in formulations aimed at addressing these ailments. Notable practices include external applications mixed with other substances, like turmeric for piles or using the root for dental hygiene. Its traditional employment is well-documented across numerous Ayurvedic texts, showcasing its significance in holistic health.

Pharmacological Properties

Recent scientific studies corroborate the traditional uses of Snuhi. Research indicates that extracts of Euphorbia nerifolia possess immunomodulatory, wound healing, antibacterial, hepatoprotective, and anti-inflammatory properties. For example, the plant has been shown to significantly enhance healing processes and offer protective effects against liver damage, aligning with its historical use in traditional remedies. The presence of active compounds like Euphol and Nerifolene underscores the plant's pharmacological relevance and supports ongoing exploration for potential therapeutic applications.

Conclusion

The exploration of Euphorbia nerifolia illustrates its dual identity as both a medicinal agent and a potential toxin. This duality reflects the broader Ayurvedic philosophy that promotes understanding the nature of substances concerning their applications. Proper purification and understanding dosages are essential to harnessing the plant's medicinal properties while mitigating risks. Thus, Snuhi serves as an exemplary case of how traditional knowledge and modern science can converge to enhance our understanding of therapeutic agents derived from nature.

FAQ section (important questions/answers):

What is Snuhi and its significance in Ayurveda?

Snuhi, known scientifically as Euphorbia nerifolia, is a significant medicinal plant in Ayurveda, categorized as an Upavisha. It is recognized for its therapeutic potential while also being poisonous if not used properly.

What are the main properties of Snuhi?

Snuhi possesses various properties such as being Kapha-vatahara, Dipana (appetizer), and Tikshna virechana (purgative). These properties make it effective in treating various conditions like Vatavyadhi and Gulma.

What are the major chemical constituents found in Snuhi?

The major chemical constituents of Snuhi include latex comprising compounds like Euphol, nerifolene, and flavonoids. These compounds contribute to its medicinal and toxicological effects.

What are the toxic effects of Snuhi if ingested?

Ingesting Snuhi latex can cause severe gastrointestinal distress, including vomiting, diarrhea, and abdominal burning. In extreme cases, it may lead to coma or even death.

How should Snuhi be purified before medicinal use?

Snuhi should undergo a purification process called Shodhana, which involves mixing it with other substances and drying it in the sun to mitigate its toxic properties before medicinal application.

What therapeutic uses does Snuhi have in Ayurveda?

Snuhi is traditionally used for treating conditions like piles, wounds, and digestive disorders. It demonstrates immunomodulatory, wound healing, and antibacterial activities, making it valuable in Ayurvedic preparations.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Snuhi (euphorbia nerifolia linn.) upavisha – a review”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Snuhi:
Snuhi refers to the plant species Euphorbia nerifolia, known for its medicinal properties as well as its potential toxicity. In Ayurveda, it is categorized as an 'Upavisha' or less harmful poison, signifying its dual role in traditional medicine. Proper administration can leverage its benefits while minimizing risks.

2) Activity:
In the context of medicinal plants, activity refers to the physiological or pharmacological effects exhibited by a substance. In the case of Snuhi, its activities include immunomodulatory, wound healing, anti-bacterial, and hepatoprotective effects, which underscore its therapeutic potential in various health conditions.

3) Nighantu (Nighamtu):
Nighantu is a term that refers to a type of traditional Ayurvedic botanical text that lists medicinal plants along with their properties, uses, and synonyms. It serves as a reference for practitioners to identify and utilize plants like Snuhi effectively in therapeutic practices.

4) Varga:
Varga translates to a category or classification in Ayurvedic literature. It is used to group together substances that share similar properties or therapeutic uses. For example, Snuhi is classified under 'Upavisha Varga,' indicating its classification as a less toxic medicinal plant.

5) Ayurveda (Ayus-veda):
Ayurveda is an ancient Indian system of medicine that emphasizes the use of natural substances, primarily plants, to promote health and treat diseases. It integrates diet, lifestyle, and herbal remedies to maintain balance and harmony in the body, exemplified by the use of Snuhi for therapeutic purposes.

6) Upavisha (Upavisa):
Upavisa denotes a classification of herbs that are less toxic but still potent. Snuhi being an Upavisa implies it can offer therapeutic benefits while requiring careful administration to avoid harmful effects.

7) Kshira (Ksira):
Ksira is a Sanskrit term for milk, often used to denote the milky latex produced by certain plants, including Snuhi. This latex contains active compounds that contribute to the therapeutic effects of the plant, making it an important ingredient in various Ayurvedic formulations.

8) Medicine:
Medicines are substances used to treat, cure, or prevent illnesses. Snuhi serves as an example of a herbal medicine, showing the intersection of traditional knowledge and modern healthcare practices in managing various health conditions.

9) Drug:
Drugs refer to substances used in the medical field for therapeutic purposes. Snuhi, with its pharmacological effects, serves as an example of how traditional plant-based drugs are incorporated into modern medicinal practices.

10) Samhita:
Samhitas are ancient Ayurvedic texts that compile medical knowledge, including drug formulations and treatment strategies. They provide the foundational guidelines for utilizing plants like Snuhi in effective health practices, ensuring historical continuity in Ayurvedic medicine.

11) Pharmacological:
Pharmacological refers to the study of how drugs interact with biological systems. It’s essential for understanding the effects of compounds derived from plants like Snuhi, influencing their potential applications in treatment protocols within the realms of traditional and modern medicine.

12) Shodhana (Sodhana):
Shodhana is a purification process in Ayurveda intended to detoxify and make medicinal substances safer for consumption. In the context of Snuhi, proper Shodhana is crucial to mitigate its toxic effects while preserving its therapeutic properties.

13) Sehunda:
Sehunda is a synonym for Snuhi, emphasizing its identity in various classical texts. This term illustrates the traditional recognition of the plant across different cultures and languages, highlighting the diversity of knowledge surrounding its uses.

14) Water:
Water plays a vital role in the preparation and administration of Ayurvedic medicines. In the context of Snuhi, water is often used in the Shodhana process to purify the latex before its therapeutic applications, ensuring safety and efficacy.

15) Purification:
Purification in Ayurvedic practices refers to processes aimed at removing toxins to enhance the safety and effectiveness of medicinal substances. For Snuhi, purification is essential to reduce its toxic effects while allowing its beneficial properties to be utilized in treatments.

16) Species:
Species refers to a group of organisms that share common characteristics. Snuhi is a specific species, Euphorbia nerifolia, which is recognized for its unique medicinal and toxicological properties, critical for classifications and treatment methodologies in Ayurveda.

17) Dravya:
Dravya is a Sanskrit term meaning substance or material, often referring to medicinal herbs or compounds in Ayurveda. Snuhi is considered a significant Dravya, embodying properties that can aid in treating various ailments when used correctly.

18) Sudha:
Sudha indicates purity in Sanskrit and is often associated with the purified form of substances used in Ayurveda. It underscores the importance of ensuring that the Snuhi latex is properly prepared to prevent adverse effects while retaining its therapeutic benefits.

19) Inflammation:
Inflammation is a biological response to harmful stimuli, and understanding its mechanisms is crucial in pharmacology. Snuhi has anti-inflammatory properties, making it useful in alleviating conditions marked by inflammation, thereby showcasing its therapeutic potential.

20) Tikshna (Tiksna):
Tikshna is a term meaning sharp or penetrating in Ayurvedic terminology, describing a quality of certain substances that can effectively cleanse or stimulate. Snuhi possesses Tikshna properties, making it useful for purging and detoxifying the body.

21) Science (Scientific):
Sciences refer to the systematic disciplines that study natural phenomena, including botany and pharmacology. The application of scientific methods to plants like Snuhi contributes to a deeper understanding of their therapeutic potential and safety.

22) Family:
Family refers to a group of related plants in taxonomy. Snuhi belongs to the Euphorbiaceae family, which is characterized by plants that often produce latex. Understanding its family helps in the identification and usage of similar species with medicinal properties.

23) Powder:
Powder refers to a finely ground form of a substance used in various medicinal applications. In the case of Snuhi, its powdered form may be utilized in Ayurvedic treatments, facilitating easy usage and dosage during therapeutic practices.

24) Patra:
Patra means leaf in Sanskrit, often classified for use in traditional medicines. The leaves of Snuhi are used in preparations for external applications, highlighting the diverse parts of the plant that provide health benefits.

25) Visha (Visa):
Visa means poison in Ayurvedic context, indicating toxicity associated with certain plants. While Snuhi possesses toxic properties, traditional practices highlight its medicinal use with caution, exemplifying the dual nature of such substances.

26) Sign:
Sign indicates manifestations or symptoms of health conditions. Recognizing signs is important for understanding how substances like Snuhi affect the body, guiding practitioners in diagnosing and treating illnesses with appropriate herbal remedies.

27) Milk:
Milk, particularly the latex of plants like Snuhi, contains compounds that are therapeutically beneficial but can also be toxic. Its use as a medicinal substance highlights the complex duality of plant-based solutions in Ayurveda, requiring careful handling.

28) Burning sensation:
Burning sensation refers to a painful bodily response that can occur due to irritants, including substances derived from Snuhi. Awareness of such sensations helps practitioners mitigate adverse effects during treatment while maximizing therapeutic outcomes.

29) Antibiotic (Antibacterial):
Antibiotic refers to substances that kill or inhibit the growth of bacteria. The anti-bacterial properties of Snuhi align it with the classes of antibiotics, emphasizing the plant's potential in managing infections.

30) Phytochemical:
Phytochemical refers to the chemical compounds found in plants that contribute to their color, flavor, and disease resistance. In Snuhi, various phytochemicals are responsible for its therapeutic effects, making it vital for researchers to study these compounds for potential medicinal applications.

31) Ksharasutra (Ksarasutra, Kshara-sutra):
Kshara-sutra is a traditional Ayurvedic therapeutic procedure involving the use of medicated thread. Snuhi latex is integral in Kshara-sutra preparations, used in surgical practices and treatment modalities for conditions like Bhagandara, showcasing its diverse applications in Ayurveda.

32) Maharashtra (Maharastra, Maha-rashtra):
Maharashtra is a state in India where Snuhi is commonly found and utilized in traditional medicine. Its geographical relevance underscores the importance of regional practices and plant availability in the application of Ayurvedic medicine.

33) Bahukantaka (Bahu-kantaka):
Bahukantaka is a specific classification of Snuhi mentioned in Ayurveda, referring to a variety known for its superior purgative properties. This classification is important for practitioners to understand the specific applications of different varieties of Snuhi.

34) Bhagandara (Bhagamdara):
Bhagandara is a condition, often translated as fistula, for which Snuhi is used as a treatment. Its role in managing this condition illustrates the practical application of Ayurvedic knowledge in addressing complex health issues.

35) Ahmednagar:
Ahmednagar is a district in Maharashtra, India, noted for its usage of traditional plants like Snuhi in local medicine. This cultural significance adds value to the study of indigenous practices and plant-based healing in the region.

36) Irritation:
Irritation refers to an inflammatory response that can ensue from exposure to toxins or chemicals. The latex of Snuhi can cause irritation, emphasizing the need for caution in its application and the importance of understanding adverse effects.

37) Container:
Container refers to any vessel used to hold materials, including herbal preparations. In preparing and storing Snuhi latex, selecting an appropriate container ensures the preservation of its medicinal properties while preventing contamination.

38) Flavonoid:
Flavonoids are a class of plant secondary metabolites with antioxidant properties. The presence of flavonoids in Snuhi contributes to its health benefits, particularly regarding its anti-inflammatory and immune-modulating effects, essential for herbal medicine research.

39) Vomiting:
Vomiting is a bodily response to toxins or irritants that can occur with inappropriate use of substances like Snuhi. Recognizing such symptoms guides practitioners in adjusting treatments and mitigating adverse effects associated with plant-based medications.

40) Burning (Burn, Burned, Burnt):
Burning refers to a painful sensation associated with irritation or toxicity. The effects of Snuhi indicate the need for awareness of burning sensations during its application, guiding practitioners in ensuring safe and effective treatment.

41) Kshara (Ksara):
Kshara indicates alkaline or caustic substances used in Ayurvedic treatment. Snuhi latex is employed in preparations associated with Kshara-sutra, reflecting its importance in traditional surgical methods and therapeutic protocols.

42) Vatari (Vata-ari, Vatavari):
Vatari is a descriptor highlighting its attribute to balance the Vata dosha in Ayurvedic medicine. Snuhi is recognized for its therapeutic potential, particularly in managing Vata-related ailments, illustrating holistic approaches in treatment methodologies.

43) Ashvin (Asvin):
Ashvin refers to the Ashvin month in the Hindu calendar, associated with specific seasonal changes. In Ayurveda, certain plants like Snuhi align with these seasonal nuances, impacting their usage based on time, availability, and traditional practices.

44) Dugdha:
Dugdha means milk or milky substances, particularly the latex from Snuhi. This milky exudate is significant due to its medicinal properties, denoting the dual characteristics of being both therapeutic and toxic.

45) Shuddha (Suddha):
Suddha signifies purity in Ayurveda, indicating the refined preparation of substances for therapeutic use. The concept of Suddha is pivotal in enhancing the efficacy and safety profile of Snuhi before its administration.

46) Sadhvi (Sadhvin):
Sadhvi implies a role associated with purity and discipline in practices. In Ayurveda, practitioners embody Sadhvi qualities when prescribing treatments like those involving Snuhi, ensuring adherence to ethical standards and traditional knowledge.

47) Nature:
Nature encompasses the inherent qualities and characteristics of entities, including plants like Snuhi. Recognizing the natural properties of such medicinal plants guides practitioners in utilizing them in alignment with their healing capabilities.

48) Indian:
Indian refers to the cultural and geographical context from which practices like Ayurveda emerge. Snuhi being an integral part of Indian traditional medicine underscores the significance of regional plants in holistic healing practices.

49) Manci (Mamci):
Manchi signifies a geographical or cultural identifier, often representing a specific locality. In relation to Snuhi, local practices in Manchi area highlight the integration of indigenous knowledge in utilizing this plant for health.

50) Sutra:
Sutra denotes a set of guidelines or instructions, particularly in Ayurvedic texts outlining procedures for treatments. Snuhi’s application in Kshara-sutra reflects this structured approach towards integrative therapies in managing diseases.

51) Udara:
Udara indicates disorders related to the abdomen, and Snuhi is utilized in treating such conditions. The relevance of Udara in Ayurvedic practices signifies the importance of understanding organ-specific treatments within holistic medicine.

52) Varti (Vartin):
Varti refers to a specific type of medicated wick or suppository used in Ayurvedic treatments. Snuhi is employed in various Varti formulations, showcasing its versatility in addressing localized conditions.

53) Gulma:
Gulma refers to abdominal tumors or masses in Ayurveda, with Snuhi recognized for its therapeutic benefits in managing such conditions. Its application highlights the role of specific herbs in traditional treatment strategies.

54) Vrana:
Vrana means wound in Sanskrit, with Snuhi used in managing wound healing processes. The plant’s properties facilitate healing, reflecting the critical role of herbal medicines in treating injuries and skin issues.

55) Sugar:
Sugar in this context refers to a sweetening agent that may be used in Ayurvedic formulations or treatment ideas. In association with Snuhi, sugar can be used to alleviate irritation caused by the plant's latex during treatments.

56) Nakar:
Nagar refers to a location, specifically a city in the context of where Snuhi might be utilized or studied. The local practices in Nagar demonstrate the cultural significance of traditional medicine in urban settings.

57) Roga:
Roga translates to disease or disorder in Sanskrit. The application of Snuhi in treating various Rogas highlights the plant's therapeutic versatility, showcasing its place within the broader frameworks of Ayurvedic health management.

58) Lepa:
Lepa refers to a medicinal paste or ointment used in topical applications. Snuhi is incorporated into various Lepa formulations aimed at treating skin conditions and wounds, demonstrating its external therapeutic applications.

59) Katu:
Katu signifies a sharp or pungent taste, often related to the pharmacological qualities of certain substances. Snuhi possesses Katu properties, indicative of its ability to stimulate digestive processes and other bodily functions.

60) Rasa (Rasha):
Rasa translates to taste in Ayurveda, essential for determining the properties and therapeutic actions of substances. Snuhi's Rasa of Katu influences its usage and effectiveness in treatment preparations, emphasizing taste's role in medicine.

61) Guda:
Guda refers to a type of substance or feature, often related to the plant’s morphology or properties. Snuhi’s Guda characteristic suggests its visual and physical attributes that are central to its identification and classification.

62) Vata:
Vata signifies one of the three doshas or energies in Ayurveda. An imbalance in Vata can lead to various health issues, and Snuhi is recognized for its therapeutic qualities in restoring Vata balance.

63) Gana:
Gana refers to a group or category in Ayurvedic taxonomy, signifying a collection of herbs with shared characteristics. In the case of Snuhi, Gana classifications help practitioners understand its specific functionalities within Ayurvedic treatments.

64) Coma:
Coma represents a state of prolonged unconsciousness that can result from toxicity or adverse effects. Awareness of such symptoms pertaining to Snuhi emphasizes the need for careful usage and monitoring in therapeutic applications.

65) Bhavaprakashanighantu (Bhavaprakasanighantu, Bhavaprakasha-nighantu):
Bhavaprakasha-nighantu is an Ayurvedic text detailing medicinal plants and their properties. It serves as an essential reference for practitioners utilizing Snuhi, illustrating how traditional knowledge is documented and disseminated in Ayurvedic practice.

66) Dhanvantarinighantu (Dhanvantari-nighantu):
Dhanvantari-nighantu is another classical Ayurvedic text that lists herbs and their benefits. It enhances the understanding of Snuhi within the framework of Ayurvedic medicine, offering insights into traditional treatments and herbal formulations.

67) Kaiyadevanighantu (Kaiyadeva-nighantu):
Kaiyadeva-nighantu is an Ayurvedic compendium documenting various plants and their uses. It provides context and reference for Snuhi, emphasizing the importance of such texts in preserving and sharing medicinal plant knowledge across generations.

68) Shalmalyadivarga (Salmalyadivarga, Shalmalyadi-varga):
Shalmalyadi-varga categorizes certain plants within Ayurvedic texts. This classification helps understand Snuhi's connections with other herbs, showcasing synergies and potential for combination therapies in Ayurvedic practice.

69) Sushruta-samhita (Susruta-samhita):
Sushruta-samhita is a foundational text in Ayurvedic surgery and medicine. The references to Snuhi within this text highlight its clinical applications, underpinning the historical context and relevance of such practices in contemporary health systems.

70) Vranashodhana (Vranasodhana, Vrana-shodhana):
Vrana-shodhana denotes a purification method specifically aimed at managing wounds. Snuhi's latex is often integral to this process, reflecting its role in traditional wound management and the practical applications within Ayurvedic medicine.

71) Atharvaveda (Atharva-Veda):
Atharva-Veda, one of the four Vedas, contains sections on medicine and healing. The references to plants like Snuhi in this ancient text signify the roots of herbal medicine within Indian traditions, establishing a historical context for current practices.

72) Dhanvantari (Dhanvamtari):
Dhanvantari is recognized as the physician of the gods in Hindu mythology and is often associated with Ayurveda. His legacy lends authority to Ayurvedic practices, including those involving plants like Snuhi deemed effective for various health issues.

73) Sarpavisha (Sarpavisa, Sarpa-visha):
Sarpa-visha refers to snake poison, and Ayurvedic texts often mention the use of Snuhi in considering treatments for venomous bites. This highlights Snuhi's perceived efficacy in traditional poison management protocols.

74) Shalmalyadi (Shalmali-adi, Salmalyadi):
Shalmalyadi often refers to a class of plants used for medicinal purposes in Ayurveda. The inclusion of Snuhi under this classification illustrates the collaborative utilization of various herbs to achieve therapeutic effectiveness.

75) Vatavyadhi (Vata-vyadhi):
Vatavyadhi denotes diseases related to Vata imbalances. Snuhi is recognized for its capacities to address these conditions, ensuring cellular and systemic balance in treatments based on Ayurvedic principles.

[Note: The above list is limited to 75. Total glossary definitions available: 144]

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Medicinal plant, Purification method, Therapeutic use, External morphology, Ayurveda treatment, Phytochemistry, Wound healing activity, Ayurvedic properties, Immunomodulatory activity, Hepatoprotective activity, Pharmacological action, Anti bacterial activity, Toxic symptoms, Treatment method, Fatal Dose, Scientific classification, Snuhi ksira, Medico legal aspect, Euphorbia nerifolia.

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