Eval of vidaryadi gana kshirpan and kshirbasti for IUGR.
Journal name: World Journal of Pharmaceutical Research
Original article title: Controlled clinical evaluation of vidaryadi gana siddha kshirpan and kshirbasti in the management of garbhashosh [iugr]
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Dr. Swati U. Pathade and Dr. Seema Mehere
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Controlled clinical evaluation of vidaryadi gana siddha kshirpan and kshirbasti in the management of garbhashosh [iugr]
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr202113-22107
Copyright (license): WJPR: All rights reserved
Download the PDF file of the original publication
Summary of article contents:
1) Introduction
The study conducted by Dr. Swati U. Pathade and Dr. Seema Mehere, published in the World Journal of Pharmaceutical Research, investigates the application of Ayurvedic treatments—Vidaryadi Gana Siddha Kshirpan and Kshirbasti—in managing Garbhashosh (Intrauterine Growth Restriction or IUGR) among pregnant women. The authors argue that while modern medicine emphasizes fetal well-being, the concept has been integral to Ayurveda for centuries. The research highlights the significance of Basti for treating Vata dosha, which is associated with conditions like Garbhashosh, and advocates for therapies that nourish and stabilize the fetus.
2) Effectiveness of Ayurvedic Treatments on Fetal Growth
The study discovered that Ayurvedic interventions, particularly the application of Vidaryadi Gana Siddha Kshirpan and Kshirbasti, significantly enhanced various clinical parameters associated with fetal growth. Key findings showed that the treatment group exhibited marked improvements in fundal height, abdominal girth, and approximate fetal weight compared to the control group. Statistical analysis using paired ‘t’ tests across various parameters demonstrated that the Ayurvedic treatments yielded significant enhancements, particularly in the trial group, suggesting their effectiveness in improving fetal health metrics.
3) Comparative Analysis of Treatment Groups
In the clinical evaluation, the researchers compared two groups: an Ayurvedic treatment group using Kshirpan and Kshirbasti and a control group receiving conventional medical interventions. The results indicated that both groups showed significant improvements; however, the trial group consistently outperformed the control group in several aspects, including increases in abdominal girth and fundal height. The statistical analysis highlighted the superior efficacy of the Ayurvedic approach, as evidenced by a higher percentage of patients achieving 'upashaya' (relief) compared to those in the control cohort.
4) Statistical Significance of the Study
Data analysis demonstrated that the total effect of therapy was significant across both groups, categorized into 'upashaya' (total relief) and 'anupashaya' (no relief). Although the differences in percentage relief between the trial and control groups were notable, statistical evaluation using the Chi-square test indicated no significant difference in overall relief effectiveness, suggesting that both treatment modalities could provide benefits. However, the Ayurvedic group had a slightly higher success rate, pointing to its potential as a more effective alternative for managing Garbhashosh.
5) Conclusion
In summary, the research emphasizes the potential of traditional Ayurvedic treatments in addressing modern public health concerns like IUGR. By combining ancient practices with clinical methodology, the study not only validates Ayurveda's relevance but also supports its integration into contemporary healthcare. Overall, the findings suggest that Vidaryadi Gana Siddha Kshirpan and Kshirbasti could serve as valuable therapeutic options, warranting further investigation and broader adoption in the treatment of pregnancy-related complications.
FAQ section (important questions/answers):
What was the main objective of the study on Garbhashosh?
The study aimed to evaluate the effects of Kshirbasti and Kshirpan on Garbhashosh, a condition indicating intrauterine growth restriction, to assess their efficacy in improving fetal growth parameters.
What treatments were compared in the study?
The study compared the effects of Vidaryadi Gana Siddha Kshirpan and Kshirbasti in the trial group against Inj. Alamine SN and Cap Alamine Forte in the control group.
What inclusion criteria were used for participant selection?
Participants included pregnant women with gestational ages between 28 to 38 weeks, aged 18 to 40 years, and having hemoglobin levels greater than 8 gm%.
How was the effectiveness of the treatments measured?
Effectiveness was assessed using clinical parameters such as abdominal girth and fundal height, as well as ultrasound parameters including Amniotic Fluid Index (AFI) and fetal weight.
What were the results for the trial group after treatment?
In the trial group, 90% of patients showed improvement (upashaya), with significant increases in fundal height, abdominal girth, amniotic fluid index, and fetal weight.
Was there a significant difference in outcomes between the groups?
While both groups showed improvements, the statistical analysis suggested that the differences in total effects were not significantly different between the trial and control groups.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Eval of vidaryadi gana kshirpan and kshirbasti for IUGR.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Anupashaya (Anupasaya):
Anupashaya refers to the category of patients in the study who did not experience any improvement in their clinical parameters after treatment. This classification is essential in clinical trials to assess the efficacy of the treatment under investigation, providing a clear distinction between effective and ineffective therapeutic outcomes.
2) Upashaya (Upasaya):
Upashaya denotes the patients who experienced improvement in their symptoms or clinical parameters following the treatment. In clinical evaluations, understanding the proportion of upashaya participants helps gauge the success of the therapy, and is vital for evaluating treatment effectiveness and making informed medical decisions.
3) Table:
In the context of this study, 'Table' refers to the structured presentation of data and results obtained from the clinical evaluations. Tables help in visualizing comparative statistics, parameter changes, and treatment outcomes coherently, facilitating easier analysis and better comprehension of the research findings.
4) Varanasi (Varanashi):
Varanasi is a city in India, significant in the field of Ayurvedic studies and traditional medicine. Its association with renowned scholars and ancient texts enhances the credibility of Ayurvedic practices. The city serves as a cultural hub where traditional knowledge is preserved and discussed in contemporary medical contexts.
5) Samhita:
Samhita refers to an ancient Indian text or compendium that outlines the principles of Ayurveda and its practices. These texts are foundational for Ayurvedic education and encompass comprehensive knowledge about herbal medicine, therapies, and health practices, laying the groundwork for further developments in the field.
6) Hindi (Himdi):
Hindi is one of the primary languages spoken in India, used for communication and education. In this study, references to Hindi suggest the availability of Ayurvedic texts, studies, and materials in this language, making the information accessible to a broader audience and facilitating the dissemination of Ayurvedic knowledge.
7) Study (Studying):
In this context, 'Study' refers to the clinical evaluation conducted to assess the efficacy of Vidaryadi Gana Siddha Kshirpan and Kshirbasti in managing Garbhashosh. Clinical studies are crucial for developing evidence-based practices in medicine, enabling practitioners to apply scientifically validated treatments in clinical settings.
8) Gana:
Gana in Ayurveda signifies a group or class of herbs or treatments that are used together for medicinal purposes. Understanding the specific ganas, like Vidaryadi, helps in formulating targeted therapies that harness the synergistic effects of various components, thereby enhancing therapeutic outcomes in patients.
9) Vidaryadi:
Vidaryadi refers to a specific group of herbal constituents used in the Ayurvedic formulation mentioned in the study. This formulation aims to improve maternal health during pregnancy, especially in cases of intrauterine growth restriction. Understanding its components is essential for recognizing its therapeutic potential.
10) Vyakhya:
Vyakhya is a term that refers to commentary or explanation accompanying a traditional text. In Ayurvedic literature, vyakhyas provide interpretations and insights into complex concepts, making them more comprehensible for practitioners and students. They enhance the understanding of Ayurvedic principles and their application in modern contexts.
11) Sanskrit:
Sanskrit is the classical language of India and the language in which many foundational Ayurvedic texts are written. Its significance lies in the preservation of ancient knowledge and the intricate details documented in traditional medical practices, ensuring that the wisdom of Ayurveda is passed down accurately through generations.
12) Bharati:
Bharati can refer to 'Bharati Academy,' which is associated with Ayurvedic literature and education. Institutions like Bharati play a crucial role in promoting Ayurvedic medicine through publishing texts, providing educational resources, and fostering research, thus enhancing the spread and understanding of Ayurvedic practices.
13) Vata:
Vata is one of the three doshas or vital energies in Ayurveda, responsible for movement and communication in the body. Understanding Vata's role is essential in Ayurvedic treatments, as imbalances can lead to various health issues, including growth restrictions during pregnancy, which is the focus of this study.
14) Vidyotini:
Vidyotini is likely a reference to a commentary or explanatory text on Ayurvedic principles. Such commentaries are essential for interpreting ancient writings, providing context and clarity to the concepts presented, thus enabling a deeper understanding of the practices and treatments outlined in traditional medicine.
15) Ayurveda (Ayus-veda):
Ayurveda is an ancient system of medicine from India, emphasizing a holistic approach to health through the balance of mind, body, and spirit. This study exemplifies Ayurvedic principles, demonstrating its relevance and application in managing contemporary health issues, such as intrauterine growth restriction.
16) Prakasha (Prakasa):
Prakasha refers to the illumination or enlightenment provided by Ayurvedic texts and teachings. It signifies the importance of light as a metaphor for knowledge and understanding in Ayurvedic practice, emphasizing the need for clarity in treatment methodologies and therapeutic approaches.
17) Pregnant:
Pregnant refers to the state of carrying a developing fetus, which is central to this study focusing on maternal and fetal health, particularly in cases of intrauterine growth restriction (IUGR). Understanding the specific needs and treatments for pregnant women is crucial in Ayurvedic and modern medicine.
18) Shosha (Sosa):
Shosha denotes the condition of depletion or deficiency in the context of Ayurveda. In this study, it refers to 'Garbhashosh,' indicating issues related to inadequate growth of the fetus. Recognizing shosha is essential for developing targeted treatments that address deficiency-related conditions during pregnancy.
19) Basti:
Basti is an Ayurvedic therapy involving the administration of medicated liquids through the rectum. It is regarded as one of the primary treatments for various ailments, especially those involving Vata dosha imbalances. This study emphasizes basti's application in managing intrauterine growth restriction.
20) Bhava:
Bhava forms an integral part of Ayurvedic nomenclature and signifies mood, feeling, or emotional state. In pregnancy, understanding bhava is important for fostering a healthy emotional environment, which can affect maternal and fetal well-being, aligning with Ayurveda's holistic principles.
21) Cita:
Sidha refers to a process of making or preparing herbal formulations that are deemed effective for treatment. In Ayurvedic practices, sidha signifies the preparation and application of therapeutic substances, ensuring that practitioners utilize well-prepared remedies for optimal patient health outcomes.
22) Kala:
Kala can refer to timing or specifics in the context of therapy in Ayurveda. In the treatment framework, understanding the optimal timing for administering therapies is vital in maximizing their effectiveness, particularly concerning gestational age and the specific needs of the patient.
23) Cow milk (Cow's milk):
Cow milk is a significant dietary component in various Ayurvedic formulations. It is recognized for its nourishing properties and is believed to promote fetal health during pregnancy. In the study, the use of cow milk highlights the emphasis on nutrition in Ayurvedic treatments.
24) Sushruta-samhita (Susruta-samhita):
Sushruta-samhita is one of the foundational texts of Ayurveda, specifically focusing on surgical procedures and techniques. Its relevance lies in its comprehensive documentation of medical practices, emphasizing the importance of ancient wisdom in modern medical approaches, particularly in maternal health.
25) Observation:
Observation refers to the careful monitoring and recording of clinical parameters throughout the study. Accurate observations are critical for analyzing treatment outcomes and validating the effectiveness of the therapeutic approaches used in the management of specific health conditions during pregnancy.
26) Vidarikanda (Vidari-kanda):
Vidarikanda is an important herb in Ayurvedic medicine known for its rejuvenating and nourishing properties. Its inclusion in the treatment highlights Ayurveda's reliance on specific plants for managing health issues, such as intrauterine growth restriction, by promoting optimal fetal development.
27) Dravyaguna (Dravya-guna):
Dravyaguna, or the science of drug properties in Ayurveda, studies the qualities and interactions of medicinal herbs and substances. This field is integral to formulating effective treatments, as it provides the rationale behind selecting specific drugs for particular conditions, such as Garbashosh.
28) Vatapitta (Vata-pitta):
Vata-pitta represents the combination of two doshas in Ayurvedic terms. Understanding this combination helps tailor treatments to patients' unique constitutional types and health conditions, which is important for personalized medicine approaches in addressing complications during pregnancy.
29) Vatadosha (Vatadosa, Vata-dosha):
Vata-dosha refers to one of the three primary energies or doshas in Ayurveda. Identifying Vata-dosha imbalances is central to Ayurvedic healing, particularly for managing conditions associated with movement and communication within the body, essential for pregnant women facing specific health challenges.
30) Developing:
Developing refers to the ongoing process of growth and maturation, particularly relevant in the context of fetal health. In this study, it underscores the importance of interventions designed to support healthy fetal development in pregnant women, highlighting the critical nature of prenatal care.
31) Punarnava (Punar-nava):
Punarnava is an Ayurvedic herb known for its rejuvenating qualities and ability to aid in tissue repair and fluid balance. Its role in the formulation reflects Ayurveda’s focus on using specific herbs to promote health and restore balance during pregnancy and in cases of growth restriction.
32) Shalparni (Salparni):
Shalparni is another herb used in Ayurvedic formulations, recognized for its therapeutic effects. The inclusion of such herbs in the study indicates the traditional reliance on plant-based remedies to support maternal and fetal health, promoting comprehensive care through herbal medicine.
33) Nighantu (Nighamtu):
Nighantu refers to Ayurvedic pharmacopoeias or lexicons that catalog medicinal plants and their properties. Understanding nighantu is vital for practitioners to correctly identify and utilize herbs within treatments, ensuring the appropriate application of traditional remedies for health concerns.
34) Prakriti (Prakrti):
Prakriti means an individual’s unique constitution or nature, determined by the balance of doshas. In Ayurveda, assessing prakriti aids in customizing treatments suited to a patient's specific needs, crucial for effectively managing health conditions during pregnancy.
35) Prasuti:
Prasuti relates to the field of obstetrics within Ayurveda, focusing on pregnancy and childbirth. Understanding prasuti is essential for practitioners to provide appropriate care during the prenatal period, ensuring the health of both mother and child throughout the pregnancy.
36) Krishna (Krsna):
Krishna may refer to a specific commentary or interpretation of Ayurvedic texts. Such interpretations enrich the understanding of classical Ayurvedic writings, making the principles and practices outlined more accessible to modern practitioners and learners in the field of medicine.
37) Disease:
Disease refers to any abnormal condition affecting the body that disrupts normal functioning. Understanding diseases within the context of Ayurveda is important for recognizing imbalances and developing effective treatment strategies, including those aimed at managing complications during pregnancy.
38) Science (Scientific):
In this context, science refers to the systematic study and application of knowledge related to health, emphasizing evidence-based approaches in medicine. The integration of scientific methods with traditional knowledge like Ayurveda reflects a modern perspective toward holistic patient care.
39) Dravya:
Dravya refers to the physical substances, particularly medicinal herbs, used in Ayurvedic treatments. Recognizing the properties and benefits of different dravyas is essential for practitioners to create effective therapeutic interventions tailored to individual patient needs.
40) Siddha:
Siddha refers to the perfected or accomplished aspect of Ayurvedic healing, focusing on the precision of remedies and treatments derived from ancient knowledge. It signifies the importance of tradition in developing successful therapeutic practices to manage health conditions effectively.
41) Garbha:
Garbha refers to the fetus or the embryo in the context of pregnancy. In Ayurveda, understanding garbha is crucial for ensuring maternal-fetal health, making preventive and curative measures tailored to the specific needs of pregnant women, particularly regarding growth and development.
42) Sariva (Shariva):
Sariva is a significant herb in Ayurvedic medicine known for its cooling and detoxifying properties. Its inclusion in the study's treatment signals its potential in supporting maternal health and promoting favorable outcomes for fetal development, underscoring the importance of herbal remedies.
43) Kshaya (Ksaya):
Kshaya refers to deficiency or depletion, often linked to health concerns like Garbhashosh, where there’s inadequate growth. Recognizing and addressing kshaya in patients is essential for practitioners to formulate effective interventions to restore balance and promote health during pregnancy.
44) Sharman (Sarma, Sharma, Sarman):
Sharma is commonly associated with authors of Ayurvedic texts or practitioners in the field. In this study's context, it may reflect the scholarly work and contributions to Ayurvedic literature, playing a role in enhancing the understanding and application of traditional practices.
45) Dosha (Dosa):
Dosha represents the fundamental energies (Vata, Pitta, Kapha) in Ayurveda that govern physiological functions. A thorough understanding of doshas is essential for practitioners to diagnose imbalances and tailor treatments suited to restore harmony within the body and promote overall health.
46) Pitta:
Pitta is one of the three doshas in Ayurveda, associated with heat, metabolism, and transformation processes in the body. Recognizing pitta imbalances is crucial for practitioners, especially when managing conditions that may arise during pregnancy, informing treatment choices to restore balance.
47) Karma (Karman):
Karma, in Ayurvedic philosophy, refers to the actions and their consequences affecting health and well-being. Understanding karma informs practitioners about the importance of lifestyle and behavioral choices in maintaining health and preventing conditions during pregnancy and beyond.
48) Delhi:
Delhi, as a major city in India, is synonymous with Ayurvedic education and practice. Its significance extends to being a hub for research and development in alternative medicine, where ancient practices are integrated with modern methodologies for contemporary healthcare solutions.
49) Water:
Water is a crucial element in Ayurvedic medicine, often emphasized for its role in cleansing and facilitating bodily functions. In the study, the reference to water highlights its necessity in various preparations and therapeutic approaches, ensuring patients are adequately hydrated for optimal health.
50) Honey:
Honey is recognized in Ayurveda for its numerous health benefits, including its antioxidant properties and role as a natural sweetener. Its inclusion in therapeutic formulations reflects Ayurveda's holistic approach, promoting nourishment and healing, particularly in treatments aimed at pregnant women.
51) Visit:
Visit refers to the clinical engagement between practitioners and patients during which assessments and treatments occur. Regular visits are essential for monitoring progress, adjusting therapies, and ensuring the ongoing health of pregnant women, thereby underscoring the importance of follow-up in medical care.
52) Roga:
Roga means disease or disorder in Ayurveda, indicating a condition that disrupts normal physiological functions. Understanding various rogas is key for practitioners to diagnose and treat effectively, guiding the selection of appropriate interventions based on individual health needs.
53) Yoni (Yonin):
Yoni is a term in Ayurveda referring to the source or origin of a condition, often related to reproductive health. Understanding yoni is significant for practitioners, as it influences choices in treatment methods and supports the holistic treatment of women’s health issues.
54) Sita (Shita):
Sita may refer to the cooling properties of certain substances and their role in Ayurvedic treatments. Recognizing the importance of cooling agents, particularly in managing heat-related conditions, is vital for developing effective treatment plans, especially those concerning maternal and fetal health.
55) Line:
Line refers to the methodology or treatment approach outlined in the study. Establishing clear lines of treatment ensures that practitioners can implement effective strategies based on standardized protocols, thereby enhancing the reliability and consistency of therapeutic outcomes.
56) Milk:
Milk, particularly cow milk, is emphasized in Ayurveda for its nourishing and restorative properties. Its inclusion in treatments reflects the importance placed on nutrition in maintaining health and supporting fetal development during pregnancy, aligning with Ayurveda's holistic health principles.
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