A review on analgesic activity of mimosa pudica
Journal name: World Journal of Pharmaceutical Research
Original article title: A review on analgesic activity of mimosa pudica
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Rutuja Sanjay Pachore, Jadhav Sir and Tushar Dukre
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: A review on analgesic activity of mimosa pudica
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr20206-17529
Copyright (license): WJPR: All rights reserved
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Summary of article contents:
Introduction
Mimosa pudica, commonly known as the sensitive plant, is a member of the Mimosaceae family and has been used in traditional medicine to treat a variety of ailments, including convulsions, infections, and wounds. This review evaluates the analgesic activity of the ethanolic extract of M. pudica, focusing on its potential therapeutic benefits as an alternative to conventional analgesics. The study included tests on laboratory rodents to assess the analgesic properties of the plant's extracts.
Analgesic Activity of M. pudica
The study assessed the analgesic activity of M. pudica using two primary methods: the hot plate test and the tail flick test. In the hot plate method, mice were divided into groups receiving either the extract or a standard analgesic (Pentazocin). The reaction time of the mice to the heat was measured to gauge the effectiveness of the extract. Results indicated that the ethanolic extract significantly increased the latency time of paw licking in a dose-dependent manner, demonstrating its analgesic potential. The tail flick test further supported these findings by measuring the withdrawal response of rats to heat stimulation, revealing similar enhancements in reaction times among the treatment groups.
Phytochemical Composition
Phytochemical screening of M. pudica has identified several bioactive compounds, including Mimosine, stigmasterol, and various fatty acids. These compounds contribute to the plant's diverse medicinal properties, such as anti-ulcer and hepatoprotective effects. The presence of these phytochemicals is crucial as they may underlie the therapeutic effects observed in the analgesic tests. Understanding the phytochemical makeup of M. pudica aids in elucidating its mechanisms of action and promoting its use in alternative medicine.
Therapeutic Applications and Significance
M. pudica has been associated with a wide range of therapeutic activities beyond analgesia, including anti-bacterial, anti-hypertensive, and anti-diabetic properties. Given the increasing incidence of chronic degenerative diseases worldwide, herbal remedies like M. pudica offer promising alternatives to expensive allopathic treatments. This potential is especially significant in regions where access to conventional medicine is limited. The exploration of its medicinal properties supports the importance of traditional plants in the pharmaceutical landscape, advocating for further research into their therapeutic applications.
Conclusion
The review highlights the pharmacological and therapeutic efficacy of M. pudica, particularly its analgesic activity. With a diverse range of beneficial effects attributed to its rich phytochemical content, M. pudica stands as a viable option for non-allopathic therapies. The increasing global trend toward natural remedies underscores the necessity of investigating such plants, as they may address the growing demand for affordable and effective healthcare solutions. Future research focusing on the extraction and characterization of active compounds will be essential to fully realize the potential of this valuable medicinal herb.
FAQ section (important questions/answers):
What is the medicinal use of Mimosa pudica?
Mimosa pudica is traditionally used to treat various ailments such as convulsion, alopecia, diarrhea, dysentery, insomnia, tumors, and snake bites. Its analgesic properties are particularly noted in folklore medicine.
How was the analgesic activity of Mimosa pudica evaluated?
The analgesic activity was evaluated using the hot plate and tail flick methods on rodents. Groups were treated with ethanolic extracts and compared with standard analgesics like Pentazocin and Diclofenac.
What phytochemicals are found in Mimosa pudica?
Phytochemical screening of Mimosa pudica reveals compounds like Mimosine, stigmasterol, D-xylose, linoleic acid, and various fatty acids, contributing to its medicinal properties.
What are the main pharmacological activities of Mimosa pudica?
Mimosa pudica exhibits various pharmacological activities including anti-ulcer, hepatoprotective, antibacterial, anti-diabetic, wound healing, and neuronal protection, highlighting its therapeutic potential.
What are the growth conditions of Mimosa pudica?
Mimosa pudica thrives in tropical and subtropical regions, prefers well-drained soils, and can survive for 1 to 2 years. Care must be taken to avoid overwatering.
Why are natural remedies like Mimosa pudica popular?
Natural remedies like Mimosa pudica are favored for being cost-effective alternatives to allopathic medications, minimizing the risk of side effects and addressing chronic health issues.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “A review on analgesic activity of mimosa pudica”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Activity:
Activity refers to the specific effects or actions that substances, such as the ethanolic extract of Mimosa pudica, exhibit when tested in biological systems. In pharmacology, these activities are typically evaluated to determine efficacy in treating conditions like pain, thereby providing evidence of therapeutic potential in medicinal research.
2) Disease:
A disease is an abnormal condition affecting the body, often characterized by specific symptoms and signs. The research emphasizes Mimosa pudica in treating various conditions like dysentery and convulsions, demonstrating the plant's importance in traditional healing practices. Identifying diseases helps guide the search for herbal medicines.
3) Animal:
Animals in the research context denote the use of various rodents for pharmacological testing of herbal extracts. The use of multiple animals for different tests supports robust scientific findings and reinforces the role of animal studies in establishing the safety and efficacy of potential medicinal compounds.
4) Pharmacological:
Pharmacological refers to the branch of medicine concerned with the study of drug action. Mimosa pudica's pharmacological properties, including analgesic activities, are explored in the review, highlighting the scientific examination of plant-derived compounds and their potential therapeutic applications, particularly in pain management.
5) Phytochemical:
Phytochemicals are bioactive compounds derived from plants that exhibit biological activity. The review notes specific phytochemicals in Mimosa pudica, linking them to various health benefits. Understanding these compounds supports the development of natural drugs while illustrating the importance of traditional knowledge in modern pharmacology.
6) Soil:
Soil, as the substrate for plant growth, plays a critical role in the cultivation and availability of medicinal plants like Mimosa pudica. The review mentions the plant's resilience in well-drained soils, emphasizing the environmental factors that influence the quality and efficacy of herbal remedies used in ethnomedicine.
7) Ayurveda (Ayus-veda):
Ayurveda is an ancient system of medicine from India emphasizing balance in body, mind, and spirit. The mention of Ayurveda highlights the traditional use of plants like Mimosa pudica for health benefits, representing a holistic approach to healing and the preservation of cultural heritage in medicinal practices.
8) Pravara:
Pravara refers to the location of the research, Pravara Rural College of Pharmacy, which emphasizes the institution's contribution to pharmacological research in rural India. The association with this educational institution showcases the integration of local traditional knowledge with modern scientific methodologies to explore herbal medicine.
9) Family:
In botanical classification, family denotes a group of related plant species. Mimosa pudica belongs to the Mimosaceae family, revealing its taxonomic relationship and potential shared therapeutic properties among related plants. Understanding plant families aids in pharmacognosy by allowing the exploration of similar active compounds across species.
10) Nature:
Nature encompasses the natural world and its ecosystems, including flora used in traditional medicine. The review underscores nature's role as a repository of medicinal resources, highlighting the importance of preserving biodiversity and traditional knowledge in developing non-toxic, natural therapeutic alternatives for various ailments.
11) Drug:
A drug is a chemical substance that has a physiological effect on the body, often used for treatment or prevention of diseases. The review suggests exploring the analgesic properties of Mimosa pudica as a natural drug, underscoring the quest for herbal alternatives in face of rising healthcare costs.
12) Nakar:
Nagar indicates a locality or city, specifically referring to Ahmednagar, where the research was conducted. The geographical context emphasizes the significance of local flora in traditional medicine practices. It highlights the integration of regional medicinal plant knowledge into scientific research, particularly relevant in rural healthcare settings.
13) Antibiotic (Antibacterial):
Anti-bacterial refers to substances that inhibit the growth of bacteria. The research highlights the anti-bacterial properties of Mimosa pudica, showcasing its relevance in treating infections and the potential to incorporate such natural compounds in developing modern antibiotics, thereby addressing growing concerns over antibiotic resistance.
14) Snake-bite:
Snake-bite refers to a wound inflicted by a snake, which can be life-threatening. The review notes the traditional use of Mimosa pudica to treat snake bites, emphasizing the importance of ethnomedicinal knowledge in addressing critical health challenges, and promoting research into natural antidotes derived from local flora.
15) Namaskari:
Namaskari is a traditional name for Mimosa pudica in Sanskrit, indicating its cultural significance in Ayurvedic medicine. The use of such names highlights the importance of language and heritage in preserving knowledge about medicinal plants and underscores the cultural relevance of traditional practices in contemporary healthcare.
16) Medicine:
Medicine denotes the science and practice of diagnosing, treating, and preventing illness. The review emphasizes the exploration of Mimosa pudica as a potential medicinal plant, bridging the gap between ancient practices and modern pharmacology, and showcasing the pursuit of holistic healing approaches based on natural remedies.
17) Epidemic:
Epidemic refers to the rapid spread of disease within a population. The review mentions chronic degenerative diseases reaching epidemic proportions, advocating for natural remedies like those derived from Mimosa pudica. This highlights the urgency and necessity of finding effective treatments to alleviate the burden on public health systems.
18) Language:
Language represents a system of communication, essential for preserving and sharing knowledge of traditional medicine. The reference to language in naming indigenous plants emphasizes the importance of cultural heritage and effective communication in advancing both research and public understanding of medicinal practices and their applications.
19) Sanskrit:
Sanskrit is an ancient language of India, often used in historical texts on medicine, including Ayurveda. The reference to Sanskrit names for Mimosa pudica underscores the deep cultural roots of traditional herbal medicine, reflecting the significance of linguistic heritage in the history and continuity of medicinal knowledge.
20) Lajjalu:
Lajjalu is a name for Mimosa pudica in Hindi, connecting the plant to its cultural relevance in India. The use of vernacular names highlights the importance of local knowledge systems in promoting awareness of medicinal plants and their therapeutic applications, fostering an appreciation for biodiversity and traditional healing strategies.
21) Species:
Species denotes the basic unit of biological classification, essential for identifying and studying organisms. The mention of Mimosa pudica as a specific species reflects its significance in ethnopharmacology and highlights the necessity of studying individual species to understand their unique properties and potential health benefits.
22) Indian:
Indian refers to anything related to India, including its people, culture, and traditional practices. Discussing Mimosa pudica as an Indian medicinal plant showcases the rich ethnobotanical heritage of the region, emphasizing the integration of local plants into healthcare systems and highlighting the importance of indigenous knowledge in medicine.
23) India:
India, a country known for its rich biodiversity and traditional medicinal practices, serves as the focal point for the study of Mimosa pudica. The country’s holistic health system and use of native plants in traditional and modern medicine illustrate the continuity of knowledge and the importance of herbal remedies.
24) Ulcer:
Ulcer refers to a sore or lesion on a mucous membrane or skin, often requiring treatment for relief and healing. The review mentions the anti-ulcer properties of Mimosa pudica, illustrating its potential therapeutic benefits, and emphasizing the importance of herbal interventions in managing gastrointestinal disorders.
25) Hindi (Himdi):
Hindi is one of India's official languages, used extensively in literature and daily communication. The use of Hindi names for Mimosa pudica emphasizes cultural identity and the relevance of local languages in preserving and promoting knowledge about traditional medicine, enhancing community awareness of herbal remedies.
26) Field:
Field refers to outdoor agricultural or natural settings where plants like Mimosa pudica are found or cultivated. The mention of field conditions reflects the significance of environmental factors in the growth and efficacy of medicinal plants, highlighting the role of proper cultivation techniques in maximizing their therapeutic potential.
27) House:
House, in this context, represents the repository of knowledge regarding medicinal plants, emphasizing the need to preserve and document traditional practices. It symbolizes the idea that nature itself houses various cures, demonstrating the critical link between human health and the natural world.
28) Male:
Male indicates the gender of animals used in the pharmacological studies. Specifying male subjects helps control biological variables and maintains consistency in research findings. Understanding gender differences in biological responses is essential for the accurate interpretation of results when assessing the efficacy of medicinal compounds.
Other Science Concepts:
Discover the significance of concepts within the article: ‘A review on analgesic activity of mimosa pudica’. Further sources in the context of Science might help you critically compare this page with similair documents:
Natural ingredient, Phytochemical screening, Analgesic activity, Chronic degenerative disease, Ethanolic extract, Tail flick test, Collection of plant, Mimosa pudica Linn., Hot plate method.