Pharmacognostical and pharmaceutical analysis of shunthi pushkarmooladi vati
Journal name: World Journal of Pharmaceutical Research
Original article title: Pharmacognostical and pharmaceutical analysis of shunthi pushkarmooladi vati
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
This page presents a generated summary with additional references; See source (below) for actual content.
Original source:
This page is merely a summary which is automatically generated hence you should visit the source to read the original article which includes the author, publication date, notes and references.
Dr. Archana, Prof. K. S. Patel, Dr. V. K. Kori, Harisha C. R. and V. J. Shukla
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Pharmacognostical and pharmaceutical analysis of shunthi pushkarmooladi vati
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr20206-17717
Copyright (license): WJPR: All rights reserved
Download the PDF file of the original publication
Summary of article contents:
Introduction
Bronchial Asthma is a chronic non-communicable lung disease characterized by airway inflammation, obstruction due to muscle spasm, and hyper-reactivity, affecting predominantly children and the elderly. In Ayurveda, this condition is referred to as "Tamaka Shwasa," and it is seen as an independent disease entity with its own pathophysiology and treatment methods. Among the treatments referenced in the Ayurvedic texts is the formulation called "Shunthi Pushkarmooladi Vati," which is made from a specific combination of herbal ingredients that aim to alleviate symptoms of asthma, particularly through supportive actions like anti-tussive, anti-inflammatory, and mucolytic properties.
Standardization and Quality Control
The study conducted a detailed pharmacognostical and pharmaceutical analysis of Shunthi Pushkarmooladi Vati to ensure its efficacy and safety as a therapeutic option for asthma management. This involved various analyses including organoleptic studies, microscopic evaluation, and physico-chemical tests that assessed characteristics such as loss on drying, ash value, pH, and hardness. For effective quality control, parameters like disintegration time and uniformity of weight were also measured. These assessments are crucial for establishing baseline quality and authenticity for herbal preparations.
Physico-Chemical Analysis
Physico-chemical analysis revealed significant findings about the formulation's properties. The loss on drying was recorded at 8.35%, with an ash value of 8.37% and a pH of 5, demonstrating that the product is acidic. The hardness of the tablets was measured at 2.5 kg/cm², indicating satisfactory structural integrity. The disintegration time of 35 minutes suggests an optimal profile for absorption upon oral administration. These parameters are vital in ensuring the formulation's bioavailability and therapeutic efficacy.
High Performance Thin Layer Chromatography (HPTLC)
High Performance Thin Layer Chromatography (HPTLC) was utilized to fingerprint the herbal formulation, confirming the presence of different active components according to their retention factors (Rf values). The HPTLC results showed 15 spots at 254 nm and 17 spots at 366 nm, supporting the formulation's richness in bioactive constituents. This robust analytical technique is important for maintaining quality standards in polyherbal preparations and provides a means of quantitative evaluation of their phytochemical profile.
Conclusion
The study effectively demonstrated the significance of standardizing the Shunthi Pushkarmooladi Vati formulation, underlining the importance of ensuring therapeutic efficacy through quality control measures. The findings suggest that this formulation, with its unique combination of herbs and supportive analyses, provides a promising approach to managing bronchial asthma, particularly for children. Furthermore, the quality parameters established serve as an essential resource for future research and routine evaluations of Ayurvedic preparations to ensure their consistent therapeutic value.
FAQ section (important questions/answers):
What are the primary characteristics of Bronchial Asthma?
Bronchial Asthma is characterized by airway inflammation, obstruction from muscle spasms, mucosal edema, mucus stagnation, hyper-reactivity to irritants, and airway remodeling, predominantly affecting children and the elderly.
What is Tamaka Shwasa in Ayurvedic medicine?
Tamaka Shwasa is a type of Shwasa Roga in Ayurveda, affecting the Pranavaha Srotas, and is described as an independent disease entity with distinct causes, pathophysiology, and management.
What is Shunthi Pushkarmooladi Vati used for?
Shunthi Pushkarmooladi Vati is a formulation used in Ayurveda primarily for managing Tamaka Shwasa, offering benefits like anti-tussive, anti-inflammatory, and mucolytic properties to help reduce asthma prevalence.
What types of analyses were conducted on Shunthi Pushkarmooladi Vati?
The study conducted pharmacognostical and physico-chemical analyses including microscopic studies, loss on drying, ash value, pH, hardness, and High Performance Thin Layer Chromatography (HPTLC) for standardization.
What were the main findings of the HPTLC analysis?
HPTLC analysis revealed 15 and 17 spots at 254nm and 366nm respectively, contributing to the formulation's quality control and standardization by providing a distinctive fingerprint for identification.
What is the significance of standardizing medicinal plants?
Standardizing medicinal plants ensures therapeutic efficacy, as active compounds may vary by geographic source, making quality maintenance essential for the effective use of plant-based medications.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Pharmacognostical and pharmaceutical analysis of shunthi pushkarmooladi vati”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Shunthi (Sunthi, Sumthi, Shumthi):
Shunthi, or Zingiber officinale, is a key herbal ingredient used in Ayurvedic formulations. It is recognized for its therapeutic properties, particularly anti-inflammatory and mucolytic effects, making it beneficial for respiratory conditions like asthma. Its role in the formulation Shunthi Pushkarmooladi Vati underscores its significance in traditional medicine practices.
2) Vati:
Vati refers to a type of Ayurvedic formulation that is prepared in a tablet or pill form. This dosage form not only enhances the palatability for patients, especially children, but also ensures appropriate and precise dosing of herbal ingredients, contributing to the overall efficiency of the treatment in managing conditions like asthma.
3) Drug:
Drugs, especially in the context of Ayurveda, are natural substances obtained from plants that exhibit therapeutic effects. The study evaluated the combination of specific drugs used in the formulation of Shunthi Pushkarmooladi Vati to support its use in treating ailments such as bronchial asthma, based on historical texts and modern research.
4) Study (Studying):
The study focuses on the pharmacognostical and pharmaceutical analysis of Shunthi Pushkarmooladi Vati. It plays a vital role in understanding the properties, quality, and efficacy of herbal formulations. By conducting such studies, researchers can validate traditional remedies and make significant contributions towards integrating them into contemporary medicine.
5) Quality:
Quality assessment of Ayurvedic formulations is crucial to ensure their therapeutic efficacy and safety. In this study, quality-related tests for Shunthi Pushkarmooladi Vati were performed to evaluate its physical and chemical properties, ensuring that the final product meets necessary standards for clinical use and patient care.
6) Tamaka:
Tamaka refers to a specific type of bronchial asthma in Ayurveda, characterized by its unique symptoms and physiological implications. Understanding Tamaka Shwasa is essential for practitioners to provide effective treatment, as the formulation Shunthi Pushkarmooladi Vati is increasingly recognized for its potential effectiveness in managing this condition.
7) Pharmacognostical:
Pharmacognostical analysis involves the study of the characteristics of drugs derived from natural sources. In the context of Shunthi Pushkarmooladi Vati, pharmacognostical methods were utilized to assess the authenticity, quality, and active constituents of the herbal ingredients, forming a critical part of ensuring therapeutic efficacy.
8) Disease:
In this context, 'disease' refers to bronchial asthma, specifically the Tamaka Shwasa. The research aims to provide evidence on how the Shunthi Pushkarmooladi Vati can aid in managing this chronic condition effectively, showcasing the relevance of traditional Ayurvedic practices in addressing persistent health issues.
9) Powder:
Powder is the formulation state of herbal ingredients before being compressed into Vati or tablets. The process of grinding raw drugs into fine powder enhances their absorption and efficacy, allowing for better medicinal outcomes. The standardized powders are crucial in ensuring uniformity and potency in the final product.
10) Table:
In the context of research, 'table' usually refers to a format of presenting data systematically. Tables in the study provide a clear and concise summary of organoleptic properties, physico-chemical analysis, and HPTLC results of Shunthi Pushkarmooladi Vati, facilitating easier interpretation and understanding of the findings.
11) Shushka (Suska):
The term 'Shushka' translates to 'dried' and refers to the parts of the plants utilized in the preparation of Ayurvedic medicines. The Shushka Kanda, Shushka Moola, and Shushka Panchanga indicate the specific dried plant parts included in the formulation, emphasizing the importance of proper selection and preparation in herbal remedies.
12) Gujarat:
Gujarat is significant in this study as it is the geographic location of the Ayurvedic pharmacy that supplied the raw materials. This region is known for its rich history of traditional medicine and contributes to the diversity of Ayurvedic knowledge and practice, including the formulations explored in this research.
13) Medium:
Medium in this context refers to the solvent used for the extraction processes in laboratory analysis. The pH and characteristics of the medium can influence the extraction of active constituents from the herbal ingredients, affecting their therapeutic efficacy and the overall quality of Shunthi Pushkarmooladi Vati.
14) Bronchial asthma:
Bronchial asthma is a chronic respiratory condition characterized by airway inflammation and obstruction. The paper discusses the prevalence and management strategies for this condition using Shunthi Pushkarmooladi Vati, illustrating the need for innovative therapeutic approaches in light of increasing asthma rates, particularly among children.
15) Ayurveda (Ayus-veda):
Ayurveda is an ancient Indian system of medicine emphasizing a holistic approach to health and wellness. It provides the theoretical foundation for the development of formulations like Shunthi Pushkarmooladi Vati, which integrates various herbs to effectively address specific health conditions, such as bronchial asthma.
16) Vyadhin (Vyadhi):
Vyadhi translates to 'disease' or 'disorder' in Ayurvedic terms and plays a crucial role in diagnosis and treatment protocols. The study analyzes the effectiveness of Shunthi Pushkarmooladi Vati in treating Vyadhi such as Tamaka Shwasa, indicating the importance of understanding disease classification in traditional medicine.
17) Nature:
Nature refers to the inherent characteristics or properties of herbal ingredients used in the formulation. Understanding the biological and pharmacological nature of components such as Shunthi and Pushkarmoola allows for the development of effective treatments while maintaining safety and efficacy in managing diseases like asthma.
18) Water:
Water is an essential solvent in the extraction and analysis of herbal formulations. Its role in the study underscores the importance of proper solubility and bioavailability of the active ingredients in Shunthi Pushkarmooladi Vati, impacting the overall therapeutic effects of the drug administered.
19) Roga:
Roga is the Sanskrit term for 'disease' in Ayurvedic terminology, reflecting the holistic approach to diagnosing and treating health conditions. The focus on Shunthi Pushkarmooladi Vati emphasizes its potential in alleviating symptoms associated with Roga like Tamaka Shwasa, supporting its credibility in Ayurvedic practice.
20) Tinospora cordifolia:
Tinospora cordifolia, also known as Guduchi, is an important medicinal plant used in Ayurveda. It is included in the formulation of Shunthi Pushkarmooladi Vati for its immune-boosting and adaptogenic properties. Its inclusion enriches the blend, enhancing its ability to combat chronic conditions like asthma.
21) Zingiber officinale:
Zingiber officinale, commonly known as ginger or Shunthi, is prominent for its antioxidant and anti-inflammatory properties. Its utilization in Shunthi Pushkarmooladi Vati signifies the importance of this herb in treating respiratory ailments, highlighting its role in Ayurvedic formulations aimed at relieving bronchial asthma.
22) Inflammation:
Inflammation is a key pathological process in diseases like bronchial asthma that leads to airway obstruction and hyper-reactivity. The study emphasizes the role of Shunthi Pushkarmooladi Vati in mitigating inflammation, showcasing its therapeutic potential in alleviating symptoms and improving respiratory function in affected patients.
23) Performance:
Performance in the context of this research refers to the efficacy and functionality of the Shunthi Pushkarmooladi Vati as a treatment for Tamaka Shwasa. Assessing the performance of the formulation through pharmacognostical and pharmaceutical analysis ensures that it meets quality standards for therapeutic use.
24) Harisha (Harisa):
Harisha C. R. is one of the co-authors and contributes to the research and findings presented in the paper. His expertise in the study of Ayurvedic pharmacology enriches the analysis of Shunthi Pushkarmooladi Vati, ensuring a thorough and comprehensive examination of the formulation's properties and effectiveness.
25) Shukla (Sukla):
V. J. Shukla, another co-author of the study, plays a significant role in the research, providing insights into the pharmaceutical aspects of Shunthi Pushkarmooladi Vati. His contributions help to validate the study's findings and enhance the overall understanding of quality analysis in Ayurvedic preparations.
26) Bitter:
Bitter is one of the organoleptic properties identified in Shunthi Pushkarmooladi Vati. Bitter taste is often associated with certain therapeutic effects in herbal medicine and is indicative of the presence of specific active compounds. This attribute may influence the acceptability and efficacy of the formulation among patients.
27) Indian:
Indians represent the population that is particularly impacted by health issues such as asthma. This study focuses on the use of Ayurvedic formulations to address these health challenges, reflecting the cultural relevance and demand for native solutions in managing chronic conditions among the Indian population.
28) India:
India is the country of origin for Ayurveda and is home to a rich diversity of medicinal plant resources. The research on Shunthi Pushkarmooladi Vati conducted in India signifies the importance of integrating traditional knowledge with contemporary scientific approaches in addressing national health concerns like asthma.
29) Patel:
Prof. K. S. Patel is a prominent figure in this research, providing guidance and support throughout the study. His expertise in Ayurvedic medicine and pharmacology is integral to the analysis of Shunthi Pushkarmooladi Vati, ensuring rigorous methodology and critical insights into the findings.
30) Edema (Oedema):
Edema refers to the accumulation of fluid in tissues, often a consequence of inflammation seen in respiratory diseases like asthma. By addressing edema in the formulation's therapeutic effect, Shunthi Pushkarmooladi Vati aims to alleviate symptoms and restore normal respiratory function in patients suffering from asthma.
31) Kori:
Dr. V. K. Kori is one of the co-authors of the study, providing valuable input in the evaluation of the pharmacognostical and pharmaceutical assessment of Shunthi Pushkarmooladi Vati. His contributions ensure a thorough exploration of the formulation's properties, enhancing its scientific basis and applicability in Ayurvedic medicine.
32) Observation:
Observation in a scientific context involves the careful monitoring and recording of phenomena during research. The observations made in the study of Shunthi Pushkarmooladi Vati helped draw conclusions regarding its properties and safety, reinforcing the need for evidence-based approaches in Ayurvedic treatments.
33) Discussion:
Discussion in the research context typically involves analyzing and interpreting the results. In this study, the discussion highlights the implications of findings related to Shunthi Pushkarmooladi Vati, relating them back to Ayurvedic principles and addressing how the formulation meets the needs of patients with bronchial asthma.
34) Substance:
Substance in a pharmacological context refers to the specific compositions and constituents of herbal medicines. Understanding the substances that make up Shunthi Pushkarmooladi Vati is essential for evaluating its therapeutic potential, dosing, and safety profile in managing asthma and other related diseases.
35) Suffering:
Suffering refers to the distress and debilitating symptoms experienced by individuals with bronchial asthma. The research into Shunthi Pushkarmooladi Vati aims to address this suffering by exploring the efficacy of this Ayurvedic formulation in alleviating asthma symptoms and enhancing the quality of life for affected patients.
36) Epidemic:
An epidemic implies a widespread occurrence of a disease in a particular community. The study highlights asthma as an epidemic in the Indian context, emphasizing the urgent need for effective interventions, such as Shunthi Pushkarmooladi Vati, to address this public health concern in a timely manner.
37) Teaching:
Teaching in relation to Ayurveda involves imparting knowledge about ancient healing practices and contemporary applications. This study contributes to the teaching of Ayurvedic principles by providing evidence-based research on formulations like Shunthi Pushkarmooladi Vati, reinforcing the importance of traditional medicine in modern healthcare settings.
38) Vitiation (Vitiated):
Vitiated refers to the disturbance or imbalance within the body, leading to diseases such as bronchial asthma. Understanding the vitiated Srotas in Ayurveda is critical for formulating treatments, as the formulation aims to restore balance and alleviate symptoms caused by various disturbances in the body’s systems.
39) Samhita:
Samhita refers to ancient texts that compile Ayurvedic knowledge and principles. These texts provide the foundational references from which the efficacy and formulations of remedies like Shunthi Pushkarmooladi Vati are derived, illustrating the relevance of historical wisdom in contemporary therapeutic practices.
40) Kshudra (Ksudra):
Kshudra is one of the five types of Shwasa (respiratory diseases) mentioned in Ayurveda. Understanding the classification of respiratory ailments like Kshudra highlights the complexity of conditions treated with formulations such as Shunthi Pushkarmooladi Vati, emphasizing the need for tailored approaches in traditional medicine.
41) Sadhya:
Sadhya translates to 'curable' in Ayurvedic terminology and refers to diseases that can be effectively treated. The classification of diseases like Tamaka Shwasa as Sadhya is important for establishing the efficacy of treatments like Shunthi Pushkarmooladi Vati, showcasing the potential for positive health outcomes.
42) Srotas (Shrotas):
Srotas are channels or pathways in Ayurveda responsible for the flow of vital substances within the body. Understanding the role of vitiated Srotas in respiratory diseases such as Tamaka Shwasa provides insights into the therapeutic action of Shunthi Pushkarmooladi Vati and guides treatment strategies.
43) Purity:
Purity denotes the quality of the herbal ingredients without contamination or adulteration. Ensuring the purity of components used in Shunthi Pushkarmooladi Vati is vital for maintaining therapeutic efficacy and safety, emphasizing the importance of quality control in Ayurvedic formulations.
44) Kanda (Kamda):
Kanda refers to the bulb or underground stem of certain plants, particularly used in Ayurvedic medicine. In the context of Shunthi Pushkarmooladi Vati, the inclusion of Shunthi (ginger) as a Kanda emphasizes the utilization of plant parts to achieve desired therapeutic effects in managing respiratory issues.
45) Ayus (Ayush):
Ayush refers to the traditional health systems of India, including Ayurveda. The inclusion of AYUSH standards in this study ensures that the methodologies align with national health policies, promoting the development and regulation of Ayurvedic formulations like Shunthi Pushkarmooladi Vati within the healthcare framework.
46) Maha (Maha°):
Maha translates to 'great' or 'major' in Sanskrit, often used to describe conditions or treatments in Ayurveda. The term can signify the seriousness of a condition like asthma, indicating the need for potent remedies such as Shunthi Pushkarmooladi Vati that address significant health concerns effectively.
47) Hand:
Hand in the context of this paper might refer to manual techniques involved in the preparation of Ayurvedic formulations or the human element in patient care, emphasizing the role of practitioners in administering treatments like Shunthi Pushkarmooladi Vati to those in need.
48) Post:
Post refers to the period following a process, often related to the analysis and evaluation stages of research. In the context of this study, it may relate to post-production assessments of Shunthi Pushkarmooladi Vati, ensuring that it meets quality standards and therapeutic efficacy before reaching patients.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Pharmacognostical and pharmaceutical analysis of shunthi pushkarmooladi vati’. Further sources in the context of Science might help you critically compare this page with similair documents:
Bronchial asthma, Organoleptic parameters, Physico-chemical analysis, Tamaka Shwasa, Pharmacognostical study, High performance thin layer chromatography (HPTLC), Chronic nature, Active constituent, Standardization test, Geographical source, Anti tussive.