Efficacy of Heen Bowitiya leaf powder in diabetes management.
Journal name: World Journal of Pharmaceutical Research
Original article title: Evaluation of the clinical efficacy of heen bowitiya leaves [osbeckia octandra] powder in the management of diabetes mellitus
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Original source:
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Balasooriya MGDN, Karunarathna WDCK and Wickramarachchi W. J.
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Evaluation of the clinical efficacy of heen bowitiya leaves [osbeckia octandra] powder in the management of diabetes mellitus
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr20207-18028
Copyright (license): WJPR: All rights reserved
Download the PDF file of the original publication
Summary of article contents:
Introduction
Diabetes mellitus is a chronic metabolic disorder characterized by high blood sugar levels resulting from the body's inability to produce or effectively use insulin. With rising incidence rates worldwide, particularly in developing countries, diabetes has become a pressing public health issue. The condition can lead to debilitating health complications if not managed properly. Traditional medicines have gained interest as potential alternatives or complements to conventional treatments. One such medicinal plant is Heen bowitiya (Osbeckia octandra), which is popularly employed in Sri Lankan indigenous medicine for managing diabetes, though its hypoglycemic effects had not been scientifically validated until this study.
Hypoglycemic Effect of Heen Bowitiya
The research aimed to explore the hypoglycemic effect of Heen bowitiya leaves. A total of 30 patients with fasting blood sugar levels between 115-200 mg/dl were selected for the study. For one month, participants consumed a powdered form of the plant, administered in warm water twice daily. The results were promising; after the treatment, the fasting blood sugar levels in patients decreased significantly, with a p-value of 0.01 indicating statistical significance. This suggests that Heen bowitiya leaves powder exhibits a notable hypoglycemic effect.
Evaluation of Liver Function
An integral part of the study involved monitoring the liver function of the participants to detect any adverse effects associated with the treatment. Liver function tests, including total bilirubin count, alkaline phosphatase, SGPT, and SGOT levels, were performed both before and after the treatment. The results indicated that all liver function parameters remained within normal ranges post-treatment, thus implying that the consumption of Heen bowitiya does not adversely affect liver health. This finding is crucial for validating the safety of incorporating this herbal remedy in diabetes management.
Implications for Ethnobotanical Research
The study's findings contribute to a broader understanding of the potential benefits of ethnobotanical plants in modern medicine. Specifically, Heen bowitiya has been noted for its antioxidant and anti-hepatotoxic properties in prior research. This aligns with previous investigations that found various plant extracts exhibiting significant hypoglycemic activities, suggesting that traditional remedies could play a pivotal role in diabetes care. The results underscore the importance of scientific validation to affirm the effectiveness of such indigenous medicinal practices.
Conclusion
In conclusion, the study demonstrates that Heen bowitiya leaves are effective in lowering blood glucose levels in diabetic patients. The positive outcomes regarding both hypoglycemic effect and safety profile emphasize the need for further research, potentially with longer follow-up periods, to better understand the full range of benefits and mechanisms underlying this herbal treatment for diabetes. This exploration not only supports the traditional uses of Heen bowitiya but also reinforces the value of integrating herbal medicine into contemporary healthcare strategies for diabetes management.
FAQ section (important questions/answers):
What is the main focus of the study on Heen Bowitiya?
The study evaluates the hypoglycemic effect of Heen Bowitiya leaves powder in managing diabetes mellitus. It aims to scientifically validate its traditional use in controlling blood sugar levels.
What were the conditions for patient selection in the study?
Thirty patients with fasting blood sugar levels between 115-200 mg/dl, aged 30-65, were selected without regard to their sex, religion, occupation, or habitat from the outpatient department.
How was the Heen Bowitiya leaves powder administered to patients?
Patients were treated with Heen Bowitiya leaves powder, prepared by dissolving 2 spoonsful in 30 ml of warm water, taken twice a day for one month.
What were the results regarding fasting blood sugar levels?
The mean fasting blood sugar level significantly decreased after treatment, with a p-value of 0.01, indicating that Heen Bowitiya leaves powder has a hypoglycemic effect.
Was there any adverse effect noted in liver function tests?
Liver function tests conducted before and after treatment showed all values remained within the normal range, indicating no adverse effects from consuming Heen Bowitiya leaves powder.
What conclusion can be drawn from the study's findings?
The study concludes that Heen Bowitiya leaves are beneficial for diabetic patients in lowering blood glucose levels, suggesting further research is warranted for long-term effects.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Efficacy of Heen Bowitiya leaf powder in diabetes management.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Blood:
Blood is a vital fluid in the body that transports oxygen and nutrients to cells while removing waste products. In the context of diabetes management, maintaining healthy blood sugar levels is crucial. The study evaluates the efficacy of Heen bowitiya leaves powder on fasting blood sugar levels in diabetic patients.
2) Powder:
Powder refers to the form in which Heen bowitiya leaves were administered to patients in the study. The leaves were processed into a powder, which was then mixed with warm water. This method of preparation helps extract the therapeutic properties of the plant, facilitating its absorption and efficacy in reducing blood sugar levels.
3) Ayurveda (Ayus-veda):
Ayurveda is a traditional system of medicine originating from India, emphasizing natural and holistic healing practices. The study is situated within the Ayurvedic framework, investigating the hypoglycemic effects of Heen bowitiya, a plant commonly used in Sri Lankan Ayurveda for treating various ailments, including diabetes.
4) Sugar:
Sugar, specifically glucose, plays a crucial role in diabetes management. In the presented study, fasting blood sugar levels were measured to assess the efficacy of Heen bowitiya leaves powder. Managing blood sugar is essential in preventing diabetes-related complications and improving overall health outcomes for patients.
5) Study (Studying):
The study examines the clinical efficacy of Heen bowitiya leaves powder in managing diabetes mellitus. It involves a systematic approach, including participant selection, treatment administration, and data analysis, aiming to scientifically validate the traditional use of this plant in treating elevated blood sugar levels.
6) Drug:
Drugs commonly refer to substances used for medical treatment. The study compares Heen bowitiya leaves powder's effectiveness to conventional drugs used in diabetes management. Understanding the role of herbal drugs expands treatment options for patients and may provide safer alternatives with fewer side effects.
7) Shri-lanka (Srilanka, Sri-lanka, Shrilanka):
Sri Lanka is the geographical context for the study, where Heen bowitiya is an endemic plant widely used in local traditional medicine. The investigation reflects the unique practices of Sri Lankan Ayurveda, emphasizing the importance of local flora in developing treatments for health issues like diabetes.
8) Lanka (Lamka, Lànkà):
Lanka, synonymous with Sri Lanka, refers to the same region and its rich heritage in traditional medicine. The study draws upon the indigenous knowledge and practices of Lanka, showcasing how local plants are integral to managing conditions such as diabetes among the population.
9) Medicine:
Medicine encompasses various practices and substances used in promoting health and treating illnesses. This study contributes to the field of medicine by exploring an herbal remedy, thereby integrating traditional practices with scientific research to potentially improve diabetes treatment methodologies.
10) Table:
In the study, tables are used to present statistical data clearly and concisely, such as the mean values of fasting blood sugar levels before and after treatment. This organized format facilitates easy comparison and understanding of the efficacy of Heen bowitiya leaves powder in lowering blood sugar.
11) Activity:
Activity in this context pertains to the biological effects of Heen bowitiya leaves powder, particularly its hypoglycemic action. The study evaluates the extent of this activity through statistical tests, establishing the leaves' potential in controlling blood sugar levels, thus contributing to therapeutic practices.
12) Habitat:
Habitat refers to the natural environment where a species resides. Heen bowitiya grows in Sri Lanka, and understanding its habitat is essential for sustainable harvesting and cultivation practices. The study connects the plant's natural surroundings to its traditional uses in local medicine for diabetes management.
13) Disease:
Disease refers to any abnormal condition affecting the body. Diabetes mellitus is a chronic disease characterized by high blood sugar levels. The study investigates the use of Heen bowitiya as a potential treatment to alleviate the symptoms and complications associated with this debilitating condition.
14) Water:
Water is a critical component in the preparation of Heen bowitiya leaves powder for treating patients. The method described in the study involves mixing the powder with warm water to enhance its efficacy. This highlights the importance of proper preparation techniques in traditional herbal medicine.
15) Food:
Food plays a significant role in managing diabetes, as diet directly impacts blood sugar levels. In this study, patients received guidance on dietary practices alongside treatment with Heen bowitiya leaves powder. This holistic approach emphasizes the importance of combining dietary management with herbal treatments.
16) Calculation:
Calculation refers to the statistical analysis performed in the study. Researchers utilized paired T-tests to analyze fasting blood sugar data before and after treatment. Accurate calculations are essential in determining the significance of the results, validating the effectiveness of Heen bowitiya leaves powder in lowering glucose levels.
17) Discussion:
Discussion is a critical section in research papers where authors interpret the results, providing context and implications. In this study, the discussion highlights the findings about the hypoglycemic effects of Heen bowitiya leaves powder, comparing them to previous research and suggesting future areas for investigation.
18) Developing:
Developing countries, such as Sri Lanka, face high rates of diabetes due to lifestyle and dietary factors. The relevance of this study stems from addressing diabetes in a developing context, demonstrating the potential of local herbal remedies to manage chronic health issues prevalent in these populations.
19) Suffering:
Suffering refers to the adverse effects endured by individuals with diabetes. The study aims to provide a natural treatment option that could alleviate the suffering of diabetic patients by effectively managing their blood sugar levels with Heen bowitiya leaves powder.
20) Epidemic:
Epidemic describes the widespread occurrence of a disease within a population. Diabetes has reached epidemic levels globally, especially in developing nations. This study is relevant in that it seeks to provide alternative management strategies through herbal medicine to combat this pressing health issue.
21) Cikitsa:
Cikitsa, a term from Ayurveda, refers to the branch of medicine focused on treatment. The study emphasizes Ayurvedic principles and traditional practices, highlighting the significance of Cikitsa in the management of diabetes through natural remedies such as Heen bowitiya.
22) Quality:
Quality addresses the overall well-being and standard of health experienced by individuals. By lowering blood sugar levels, the study aims to improve the quality of life for diabetic patients, showcasing the importance of effective treatment options in managing chronic illnesses.
23) Life:
Life represents the human experience, which can be significantly affected by chronic conditions like diabetes. The study ultimately seeks to improve the life quality of patients through effective management strategies, demonstrating how local herbal treatments can play a role in enhancing health outcomes.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Efficacy of Heen Bowitiya leaf powder in diabetes management.’. Further sources in the context of Science might help you critically compare this page with similair documents:
Diabetes mellitus, Laboratory test, Hypoglycemic activity, Fasting blood sugar level, Liver function test, Hypoglycemic effect, Indigenous medicine, Gampaha Wickramarachchi Ayurveda Institute, Chronic Metabolic Disorder, Oral hypoglycemic drug, Patient's quality of life, Endemic plant.