Effect of cinnamon extract on gingival health

a clinico-microbiological study

| Posted in: Health Sciences Science

Journal name: World Journal of Pharmaceutical Research
Original article title: Effect of cinnamon extract on gingival health
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
This page presents a generated summary with additional references; See source (below) for actual content.
Subtitle: a clinico-microbiological study

Original source:

This page is merely a summary which is automatically generated hence you should visit the source to read the original article which includes the author, publication date, notes and references.

Author:

Abhijit Dey, Vivekananda Marenahally Rangaraju, Harsha Mysore Babu and Shivaprasad Dasappa


World Journal of Pharmaceutical Research:

(An ISO 9001:2015 Certified International Journal)

Full text available for: Effect of cinnamon extract on gingival health

Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research

Doi: 10.20959/wjpr202010-18070

Copyright (license): WJPR: All rights reserved


Download the PDF file of the original publication


Summary of article contents:

Introduction

The study titled "Effect of Cinnamon Extract on Gingival Health: A Clinico-Microbiological Study" aimed to explore the efficacy of cinnamon as a mouthwash for the treatment of gingivitis, compared to the widely used chlorhexidine mouthwash. Gingivitis, typically caused by plaque accumulation, can progress to more severe periodontal diseases if not adequately managed. The study recognized that while chlorhexidine is regarded as a gold standard for plaque control, it has associated side effects that may discourage long-term use. Cinnamon, known for its antimicrobial and anti-inflammatory properties, presents an alternative worth investigating for oral hygiene and gingival health.

Antimicrobial Properties of Cinnamon

The research conducted an in vitro analysis to determine the minimum inhibitory concentration (MIC) of cinnamon extract against common oral pathogens, specifically Streptococcus gordonii and Streptococcus oralis. It was found that a 10% concentration of cinnamon extract significantly inhibited bacterial growth, making it suitable for further clinical testing. The study used this concentration for an in vivo randomized controlled trial involving 30 subjects, divided into two groups receiving either scaling plus cinnamon mouthwash or scaling plus chlorhexidine mouthwash. The antimicrobial efficacy of cinnamon was underscored by its statistically significant impact on reducing microbial load.

Clinical Parameters and Efficacy

Clinical parameters such as Plaque Index (PI), Gingival Index (GI), and Sulcus Bleeding Index (SBI) were measured at baseline and after one month of treatment. Both cinnamon and chlorhexidine mouthwashes showed significant improvements in these indices, indicating a reduction in plaque accumulation and gingival inflammation. While the chlorhexidine group exhibited a slightly higher reduction in overall plaque scores, the difference was not statistically significant. This finding highlights cinnamon's effectiveness as an alternative intervention for managing gingivitis.

Microbial Analysis and Results

The microbiological assessment through Gram staining revealed that both groups experienced a reduction in Gram-positive and Gram-negative organisms. Although there was a quantitative decrease in bacterial scores in both groups after one month, the intergroup comparisons did not yield statistically significant differences. This outcome suggests that while both treatments are effective at reducing bacterial presence, the difference in their efficacy may not be clinically relevant, reinforcing cinnamon's potential as a comparable option to chlorhexidine.

Conclusion

The study concluded that a 10% cinnamon mouthwash is almost as effective as 0.2% chlorhexidine in treating chronic generalized gingivitis, with significant reductions in clinical parameters observed compared to baseline measurements. This research encourages the consideration of herbal alternatives like cinnamon for oral health, particularly due to the reduced side effects associated with natural products. The findings underscore the need for further studies to explore the long-term benefits and feasibility of incorporating cinnamon mouthwash into routine oral hygiene practices.

FAQ section (important questions/answers):

What is the purpose of the study involving cinnamon extract?

The study assesses the efficacy of cinnamon extract as a mouthwash for treating gingivitis, comparing its effectiveness to 0.2% chlorhexidine.

What parameters were evaluated in this cinnamon extract study?

Clinical parameters included plaque index, gingival index, and sulcus bleeding index, alongside microbiological analyses using Gram staining techniques.

What was the primary finding regarding cinnamon mouthwash effectiveness?

The study found that 10% cinnamon mouthwash is almost equally effective as 0.2% chlorhexidine for treating chronic generalized gingivitis.

How was the cinnamon mouthwash prepared for the study?

Cinnamon powder was mixed with ethanol and distilled water, combined with propylene glycol, flavoring agents, and preservatives to create a 10% mouthwash.

What are the inclusion criteria for participants in the study?

Participants aged 18-45 with clinical signs of gingivitis, no recent dental treatments, and no contraindicating conditions were included in the study.

What statistical methods were used in analyzing the study results?

The study utilized descriptive statistics, unpaired ‘t’ tests, chi-square tests, and paired sample ‘t’ tests to evaluate clinical and microbiological parameters.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Effect of cinnamon extract on gingival health”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Cinnamon:
Cinnamon, derived from the bark of the Cinnamomum tree, is a popular spice known for its flavor and aroma. It possesses medicinal properties such as antimicrobial and anti-inflammatory effects, making it a candidate for oral hygiene products. Its historical use in various cultures underscores its significance in traditional medicine and culinary applications.

2) Study (Studying):
The study emphasizes the importance of investigating effective treatments for gingivitis. It assesses the efficacy of cinnamon as a mouthwash compared to traditional chemical agents. Results provide insights into alternative oral hygiene methods, supporting research and exploration in herbal medicine, which is crucial for public health and dental care advancements.

3) Table:
Tables are essential in research for presenting structured data concisely. They allow for easy comparison of clinical parameters and statistical results between different groups, such as treatment outcomes in this study. Effective table use enhances readability and facilitates the understanding of key findings, contributing to the overall clarity of the research.

4) Activity:
Activity refers to the functional aspects or effects of substances like cinnamon in this study. The antimicrobial and anti-inflammatory activities of cinnamon are explored, indicating its potential in oral health. Understanding the biological activities of compounds helps in evaluating their therapeutic relevance and application in treating diseases like gingivitis.

5) Disease:
Diseases often refer to pathological conditions resulting from infections or inflammation. In this study, gingivitis serves as an example of a disease that can lead to more severe periodontal issues. Addressing diseases through alternative treatments like cinnamon mouthwash emphasizes the importance of preventive oral healthcare in reducing systemic disease risks.

6) Bleeding:
Bleeding is a clinical sign of gingivitis and is measured using the Sulcus Bleeding Index (SBI). It indicates inflammation and tissue health in periodontal research. Reduction in bleeding scores over treatments is a crucial outcome, signaling improved gingival health. Monitoring bleeding contributes to assessing the effectiveness of oral hygiene interventions.

7) Hygiene (Hygienic):
Hygiene pertains to practices that maintain health and prevent disease. In the context of oral hygiene, it emphasizes the removal of plaque and bacteria to prevent gingivitis. This study assesses the effectiveness of various mouthwash treatments, highlighting the ongoing need for effective hygiene practices in dental care for overall health.

8) Powder:
Powder refers to the form in which cinnamon is prepared for the mouthwash in this study. The preparation process involves grinding the bark into a fine powder, crucial for ensuring proper extraction of active compounds. The use of powdered herbs in formulations can enhance bioavailability and efficacy in therapeutic applications.

9) Antibiotic (Antibacterial):
Anti-bacterial refers to properties that specifically target and inhibit bacterial growth. The focus on anti-bacterial activity in the study underscores the need for effective oral hygiene products that can combat pathogenic bacteria associated with gingivitis, emphasizing the potential of cinnamon as a natural alternative to chemical mouthwash formulations.

10) Gupta:
Gupta refers to the researcher mentioned in the study, whose previous work provides a comparison point for the findings regarding the efficacy of cinnamon mouthwash. Referencing prior research contributes to the credibility of the current study, situating it within ongoing scientific discourse and enhancing the reliability of the findings.

11) Drug:
Drug in this context refers to substances used in treatment, which include both conventional medications and herbal alternatives like cinnamon. The exploration of cinnamon as a drug highlights the trend towards integrating natural products into therapeutic regimens, as well as the importance of assessing their clinical effectiveness and safety.

12) Cinnamomum zeylanicum:
Cinnamomum zeylanicum is the scientific name for the cinnamon tree. Understanding its classification underscores the relevance of botanical identity in pharmacology. The plant's traditional uses and recent research highlight its potential health benefits, particularly in oral care, aligning with the study's emphasis on alternative treatments for gingivitis.

13) Medicine:
Medicine encompasses the practices and substances used to diagnose, treat, and prevent disease. In this study, the term relates to the use of cinnamon as a potential medicinal agent for gingivitis. Its incorporation into oral healthcare practices reflects the growing interest in herbal remedies and their role in preventive medicine.

14) Surface:
Surfaces pertains to the areas in the mouth that come into contact with treatments. In this research, the focus is on the oral surfaces where plaque and bacteria accumulate. Effective cleaning of these surfaces is essential for preventing gingivitis, signifying the importance of selecting appropriate mouthwash formulations for optimal efficacy.

15) Water:
Water is a critical component in the formulation of the cinnamon mouthwash. It serves as a solvent to extract active compounds from cinnamon and as a dilution medium for other ingredients. In the context of oral hygiene, water also plays a vital role in rinsing and cleaning the mouth, supporting hygiene practices.

16) Gold (Golden):
Gold in this context symbolizes the standard or benchmark, particularly referring to chlorhexidine as the established treatment for gingivitis. This study compares cinnamon mouthwash to the gold standard to evaluate its effectiveness, showcasing the continuing quest for effective and safer alternatives in dental treatments within the oral healthcare field.

17) Inflammation:
Inflammation is a biological response to harmful stimuli, including infection. In this study, gingival inflammation is a key focus, as it underlies gingivitis. Understanding the role of inflammation in oral health is critical for developing effective treatments, particularly those that can mitigate inflammatory responses, such as cinnamon's anti-inflammatory properties.

18) Karnataka:
Karnataka is the Indian state where the study was conducted, providing geographical context for the research. The local relevance of traditional practices in dental care informs the understanding of cinnamon's use as a natural remedy within the cultural framework, showcasing regional beliefs in herbal treatment efficacy and accessibility in oral healthcare.

19) Field:
Fields refers to the distinct areas of study within the dental and medical research disciplines. The research spans various fields, including microbiology, pharmacology, and dentistry, underscoring the interdisciplinary approach required to grasp the complexities of periodontal diseases and effective therapeutic interventions through natural remedies.

20) Post:
Post typically refers to the period following an intervention, such as the follow-up evaluation after one month in this study. Monitoring changes in clinical and microbiological parameters post-treatment is essential for assessing the efficacy of the interventions, providing valuable data on long-term effects and guiding future research directions.

21) Accumulation (Accumulating, Accumulate):
Accumulation in this study pertains to the buildup of dental plaque, which is a primary cause of gingivitis. Understanding plaque accumulation and its impact on oral health is crucial as it directly relates to disease progression, informing effective prevention strategies to maintain healthy periodontal conditions through consistent oral hygiene practices.

22) Measurement:
Measurement, a subset of measurements, signifies the process of obtaining quantifiable data to support research findings. In the context of this study, precise measurements of clinical outcomes are crucial for determining the impact of different treatments on gingivitis, enhancing the scientific rigor and validation of the study’s conclusions.

23) Discussion:
Discussion is a critical section in research papers where findings are interpreted in the context of existing literature. It allows researchers to explore implications, propose future research directions, and contextualize results within broader scientific and clinical frameworks. This study’s discussion highlights cinnamon's potential role in dental care and alternative medicine.

24) Container:
Container refers to the vessel used for preparing the cinnamon mouthwash. The choice of appropriate containers is important in maintaining the integrity of the ingredients during the preparation process. Proper containment ensures that the properties of cinnamon are preserved, impacting the effectiveness of the final oral hygiene product.

25) Harsha (Harsa):
Harsha refers to one of the researchers involved in the study, contributing to the credibility and authority of the research team. Each researcher’s background and expertise enhance the study's comprehensive approach, ensuring thoroughness and reliability in exploring the efficacy of cinnamon mouthwash against gingivitis.

26) Mysore:
Mysore, a historic city in Karnataka, connects to the study's academic and cultural roots. The inclusion of this location provides contextual relevance, reflecting the traditional use of cinnamon in local practices and enhancing the study's significance by linking contemporary research with historical medicinal uses.

27) Family:
Family in this context relates to the taxonomic classification of plants, specifically the Lauraceae family to which cinnamon belongs. Understanding botanical classifications aids in recognizing the relationships and properties of various plants, guiding researchers in exploring the medicinal properties and potential applications of different natural remedies.

28) Nausea:
Nausea refers to a feeling of unease in the stomach often associated with various conditions. Historically, cinnamon has been used to alleviate nausea and other gastrointestinal issues, highlighting its traditional medicinal use that informs contemporary explorations of its broader health benefits, including in oral care and hygiene practices.

29) Reason:
Reason signifies the motivation behind the study, which is to explore alternative treatments for gingivitis using natural substances like cinnamon. Understanding the underlying reasons for researching herbal remedies reflects a growing trend in searching for safer, alternative methods of treatment that minimize side effects associated with traditional pharmaceuticals.

30) Medium:
Medium in this study refers to the substance used for culturing bacteria, specifically the Brain Heart Infusion (BHI) liquid culture medium. The medium is crucial for supporting bacterial growth during experiments, ensuring that accurate evaluations of antimicrobial activity are possible when testing cinnamon against oral pathogens.

31) Nagara (Naga-ra):
Nagara, referring to a geographical location in Karnataka, ties into the regional significance of the research. The local context enriches understanding the cultural background regarding herbal medicine, emphasizing the relevance of utilizing locally sourced plants, like cinnamon, in formulating effective solutions for oral health challenges.

32) Aroma (A-roma):
Aroma refers to the distinctive scent of cinnamon, which is one of its appealing features alongside its medicinal properties. The pleasant aroma contributes to its use in oral care products, enhancing user experience and acceptance. Aroma plays a role in consumer preferences for herbal treatments in dentistry and holistic medicine.

33) Glass:
Glass signifies the material used for certain laboratory equipment such as test tubes and beakers in the preparation and assessment of cinnamon mouthwash. The use of glass containers is crucial in laboratory settings to prevent contamination, ensuring the reliability of results, particularly when investigating the efficacy of herbal treatments.

34) Babu:
Babu, as mentioned, refers to one of the researchers in the study. The contributions of each researcher, including their expertise and background, lend credibility to the investigation into the effectiveness of cinnamon mouthwash. It is important to highlight their role in fostering a thorough exploration of the subject matter.

35) Food:
Food relates to the broader discussion about the cultural significance of cinnamon, commonly used as a spice in various cuisines. Its classification as a food item enhances the appeal of cinnamon in herbal medicine, bridging the gap between culinary and therapeutic applications, thus playing a role in its acceptance as a treatment.

36) Tree:
Tree in this context refers to the cinnamon tree from which the essential bark is harvested. Understanding the source of the cinnamon used in the study helps clarify its properties and applications in oral care. The tree's botanical attributes are essential for comprehending the medicinal and therapeutic benefits attributed to cinnamon.

37) Sign:
Sign in this research context usually refers to clinical indicators of gingivitis, such as bleeding or inflammation. Recognizing these signs is crucial for assessing periodontal health and determining treatment efficacy. Signs serve as objective measures in understanding disease progression and the effectiveness of interventions focused on oral hygiene.

38) Hand:
Hand refers metaphorically to the preparation and application process in studies like this where manual techniques are involved. It signifies personal involvement in the formulation of treatments, underscoring the importance of traditional knowledge in medicinal preparation and the artisanal quality of creating effective natural remedies for oral health.

Other Science Concepts:

[back to top]

Discover the significance of concepts within the article: ‘Effect of cinnamon extract on gingival health’. Further sources in the context of Science might help you critically compare this page with similair documents:

Essential oil, Statistical analysis, Clinical trial, Randomized controlled clinical trial, Systemic disease, Periodontal disease, Antimicrobial activity, Chlorhexidine mouthwash, In vitro analysis, In vivo study, Antibiotic resistance, Minimum inhibitory concentration (MIC), Microbiological parameters, Plaque index (PI), Sulcus bleeding index (SBI), Gingival index (GI), Gingival health, Clinical parameter, Cinnamon extract.

Let's grow together!

I humbly request your help to keep doing what I do best: provide the world with unbiased sources, definitions and images. Your donation direclty influences the quality and quantity of knowledge, wisdom and spiritual insight the world is exposed to.

Let's make the world a better place together!

Like what you read? Help to become even better: