Randomized trial on homoeopathic treatment for post-menopausal symptoms.

| Posted in: Science

Journal name: World Journal of Pharmaceutical Research
Original article title: Randomised single blind placebo control trial to assess the efficacy of homoeopathic medicines in the treatment of post menopausal symptoms
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Author:

Tarkeshwar Jain and Juhee Jain


World Journal of Pharmaceutical Research:

(An ISO 9001:2015 Certified International Journal)

Full text available for: Randomised single blind placebo control trial to assess the efficacy of homoeopathic medicines in the treatment of post menopausal symptoms

Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research

Doi: 10.20959/wjpr202014-19104

Copyright (license): WJPR: All rights reserved


Download the PDF file of the original publication


Summary of article contents:

Introduction

Menopause marks the end of a woman’s reproductive years, characterized by the cessation of ovarian function and resulting in various physical and psychological symptoms. This period occurs, on average, at 46.2 years for Indian women and may include symptoms such as hot flushes, irritability, mood swings, insomnia, and anxiety. The study presented was a randomized single-blind placebo-controlled trial aimed at assessing the efficacy of individualized homeopathic medicines in treating postmenopausal symptoms compared to a placebo.

Efficacy of Individualized Homeopathic Medicines

The primary finding of the study indicated that individualized homeopathic medicines were statistically more effective than placebo in alleviating postmenopausal symptoms. Using the Menopause Rating Scale (MRS) to measure symptom severity, results showed that scores in the treatment group (Group A) demonstrated significant improvement compared to those in the placebo group (Group B). In particular, the treatment with homeopathic remedies led to a greater reduction in symptom severity, as reflected in the mean scores before and after treatment.

Sample Characteristics and Symptoms

In total, 70 women with postmenopausal symptoms participated in this study, with a distribution of ages primarily within the 43-50 year demographic. Most participants witnessed naturally occurring menopause (80%) rather than surgical (20%). The predominant symptoms included anxiety (97.14%), loss of libido (85.71%), and joint pains (84.28%). The study highlighted that the most common associated complaint was irritability coupled with palpitations, affecting 34.28% of the participants.

Analysis of Homeopathic Medicines Used

Among the homeopathic treatments dispensed, Lachesis was the most frequently indicated remedy, prescribed to 20% of the treatment group. Other remedies included Sulphur, Pulsatilla, and Sepia, each accounting for 14.28% of the prescriptions. The findings emphasized the importance of a personalized approach in homeopathy, where the selection of the remedy is based on a comprehensive understanding of the individual’s symptomatology.

Conclusion

The findings from the study support the efficacy of individualized homeopathic medicines in treating postmenopausal symptoms compared to a placebo. While the results reflect promising evidence for homeopathy as a treatment option, the limitations of sample size and study duration warrant further research. Future studies with larger sample sizes and varied methodologies may enhance the validity of results, ultimately bolstering homeopathy's reputation in managing postmenopausal symptoms and improving women's health outcomes.

FAQ section (important questions/answers):

What was the aim of the study on homoeopathic medicines?

The study aimed to assess the efficacy of individualized homoeopathic medicines in treating post-menopausal symptoms compared to a placebo.

What symptoms were associated with menopause among participants?

Symptoms included hot flushes, irritability, mood swings, insomnia, vaginal dryness, and anxiety, affecting the patients' overall well-being.

How many participants were involved in the study?

A total of 70 cases of post-menopausal symptoms were initially selected, with 64 participants completing the trial.

What method was used for assessing the effectiveness of treatments?

The Menopause Rating Scale (MRS) was used for assessment and reassessment after six follow-ups.

What were the study results regarding homoeopathic medicines?

The study found a statistically significant difference, indicating that individualized homoeopathic medicines were more effective than placebo in alleviating symptoms.

What recommendations were made for future research?

The study suggested that larger sample sizes and varied study designs are needed for more reliable results in evaluating homoeopathic treatments for post-menopausal symptoms.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Randomized trial on homoeopathic treatment for post-menopausal symptoms.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Medicine:
Medicines refer to substances used to diagnose, treat, or prevent disease. The plural form emphasizes the variety of homeopathic remedies explored within the study. Individualized homeopathic medicines play a crucial role in the research, showcasing their potential effectiveness in addressing the specific symptoms experienced by postmenopausal women.

2) Study (Studying):
A study is a systematic investigation aimed at discovering or interpreting facts, examining relationships, and evaluating interventions. In this context, the randomized single-blind placebo-controlled trial was conducted to assess the effectiveness of individualized homeopathic treatments in alleviating postmenopausal symptoms in women.

3) Post:
Post signifies 'after' or 'following.' It contextualizes the timing of events, such as postmenopausal symptoms that occur after a woman experiences menopause. Understanding postmenopausal symptoms helps healthcare providers address the challenges women face during this transitional period, providing necessary research to find effective treatments.

4) Table:
A table is a structured arrangement of data in rows and columns, used for organizing and presenting information clearly. In the study, tables presented data on the distribution of cases, symptoms, and treatment outcomes, enabling easy comparison and analysis of the results between different groups.

5) Anxiety:
Anxiety is a mental health condition characterized by feelings of worry, fear, or apprehension, often impacting daily functioning. In the study, anxiety was a significant symptom reported by many participants, underscoring the need for effective treatment modalities, such as individualized homeopathic medicines, to alleviate such distress.

6) Jaipur:
Jaipur is the capital city of Rajasthan, India, and serves as the study's geographical context. Conducting the research in Jaipur provides insight into the experiences of local women undergoing menopause, reflecting the socio-economic and cultural factors that impact health and treatment expectations within that region.

7) Pain:
Pain is an unpleasant sensory experience signaling potential harm or injury. In the study, various forms of discomfort, including joint pain, were reported by participants. Understanding pain's impact on postmenopausal women's quality of life highlights the significance of treatment approaches seeking to alleviate such symptoms effectively.

8) Rajasthan:
Rajasthan is a state in northern India, noted for its diverse culture and significant population. The study's location within Rajasthan provides context for understanding the prevalence of postmenopausal symptoms faced by women in this region. It also highlights potential cultural influences on healthcare practices and beliefs.

9) Indian:
Indian refers to the nationality or cultural identity of people from India. The term is pertinent in the study, as it reflects the specific population sample (Indian women) under investigation regarding postmenopausal symptoms, allowing for a more tailored approach to understanding their healthcare needs and treatment responses.

10) Karnataka:
Karnataka is a state in southwestern India, providing geographical context regarding the study's comparative findings to previous research conducted there. Mentioning Karnataka helps illustrate regional differences in menopausal age, symptoms, and treatment modalities, thus enriching the overall understanding of menopause among Indian women.

11) Observing:
Observing refers to the act of monitoring or watching with attention to detail. In the study, observing patient responses to treatment is essential to evaluate the efficacy of individualized homeopathic medicines. Accurate observation enables researchers to identify changes in symptoms and guide treatment modifications throughout the investigation.

12) Suffering:
Suffering denotes experiencing pain, distress, or hardship. In the context of the study, suffering can describe the challenges faced by women dealing with postmenopausal symptoms, motivating the need for effective treatments. Understanding patient experiences of suffering can shape compassionate care and targeted therapeutic interventions.

13) Composite:
Composite refers to something made up of various parts or elements. In the study, composite scores represent the cumulative assessment from the Menopause Rating Scale (MRS), enabling researchers to gauge overall symptom severity effectively. This multifaceted approach enhances understanding of treatment outcomes across different dimensions of symptoms.

14) Disease:
Disease denotes any deviation from health condition, encompassing various physical and mental health disorders. Addressing diseases related to menopause, such as anxiety or depression, is crucial for improving women's quality of life. The study's goal was to assess treatment measures that mitigate disease-related symptoms during menopause.

15) Company:
A company in this context refers to an organization, specifically a manufacturer of homeopathic medicines. Quality control and certification of the company ensure the medicines used in the study meet safety and efficacy standards. This contributes to the reliability of study results and ethical treatment practices.

16) Observation:
Observation involves carefully watching and noting phenomena or changes. In the study, observation plays a crucial role in assessing the participants’ responses to treatment over time, which aids in evaluating the effectiveness of individualized homeopathic medicines while ensuring participant safety throughout the study's duration.

17) Discussion:
Discussion is a critical aspect of research where findings are analyzed, interpreted, and put into context. In this study, the discussion section synthesizes the results, comparing them to existing literature on postmenopausal symptoms and homeopathic treatments, thus contributing to the broader knowledge base in the field.

18) Depression:
Depression is a mood disorder characterized by persistent feelings of sadness, loss of interest, and other emotional and physical symptoms. The study acknowledges depression as a common complaint among postmenopausal women, necessitating effective treatment options like individualized homeopathic medicines to address mental health alongside physical symptoms.

19) Sweating (Sweat):
Sweating is a physiological response often associated with menopause due to hormonal changes. Symptoms like hot flashes include episodes of sweating, which significantly affect women's comfort and well-being. Understanding the prevalence of sweating as a symptom underscores the importance of finding effective relief through treatments.

20) Meeting:
Meeting refers to gathering people for a discussion or exchange of information. In the context of the study, meetings might relate to the interactions between participants and healthcare providers, fostering open communication that can enhance the understanding of symptoms, treatment changes, and overall health management during menopause.

21) Bengal (Bemgal):
Bengal refers to a region in eastern India associated with its unique cultural traditions and possibly related research findings on menopause. Mentioning Bengal helps contextualize comparative studies on postmenopausal symptoms across different Indian states while highlighting region-specific health concerns and treatment practices for women undergoing menopause.

22) Visit:
Visit denotes attending a consultation or appointment. In the study context, visits are significant as they allow for detailed assessment of participants' conditions and responses to treatment. Frequent visits foster trust and dialogue between participants and healthcare providers, which is essential for effective symptom management.

23) Itagi:
Itagi likely refers to a researcher or author associated with previous studies on menopause. Mentioning Itagi connects the current research to previous findings, thereby establishing a continuum of knowledge and emphasizing the growing academic interest in understanding menopause and its treatment options among Indian women.

24) Field:
Field refers to an area of study or profession. In the context of health research, it signifies the domain of inquiry involving menopause and treatments like homeopathy. This field encompasses a variety of aspects, including symptomatology, epidemiology, and the effectiveness of various treatments, with continuous advancements required.

25) Drug:
A drug is a chemical substance used in the diagnosis, treatment, or prevention of illness. The study evaluates the effectiveness of individualized homeopathic medicines compared to standard drugs for postmenopausal symptoms, underlining the diverse approaches available in women's health treatment.

26) Beta:
Beta is a statistical term often used in research to denote the probability of a Type II error, which means failing to reject a false null hypothesis. In the context of the study, beta signifies the study's power, ensuring that the analysis adequately detects differences in treatment efficacy between the two groups.

27) Mud:
Mood pertains to emotional states that can impact an individual's daily life. The study identifies mood swings and anxiety as significant symptoms experienced by women during menopause. Understanding the interplay between mood and menopausal symptoms highlights the importance of effective management strategies in treating this population.

28) Pur:
Poor signifies a lack of something, often referring to quality or condition. In the study, poor compliance by participants can hinder the evaluation and reliability of treatment outcomes. Understanding factors contributing to poor compliance helps identify systemic challenges in the healthcare delivery process and improve future studies.

Other Science Concepts:

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Discover the significance of concepts within the article: ‘Randomized trial on homoeopathic treatment for post-menopausal symptoms.’. Further sources in the context of Science might help you critically compare this page with similair documents:

Follow-up, Marked improvement, Hormonal balance, Hot flushes, Placebo control trial, Psychological symptoms, Statistically significant difference, Natural menopause, Surgical menopause, Randomized allocation, Post Menopausal Symptoms, Individualized Homoeopathic Medicine.

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