Study of Siddha drugs for treating depression (viyagula unmatham).
Journal name: World Journal of Pharmaceutical Research
Original article title: An open clinical study of siddha drugs “thirutharatchatha chooranam” (internal) and “arugan ver thylam” (external) in the treatment of “viyagula unmatham” (depression)
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Original source:
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Dr. Siva Josyaa, Dr. N. J. Muthukumar and Dr. V. Banumathi
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: An open clinical study of siddha drugs “thirutharatchatha chooranam” (internal) and “arugan ver thylam” (external) in the treatment of “viyagula unmatham” (depression)
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr20192-14090
Copyright (license): WJPR: All rights reserved
Summary of article contents:
Introduction
Depression, characterized by a persistent sense of sadness, loss of interest, and various cognitive and physical complaints, is a significant public health concern affecting people worldwide. The prevalence of depressive disorders is substantial, with approximately 10% of adults, 8% of teenagers, and 2% of preteen children experiencing symptoms similar to modern understandings of depression. Within the Siddha system of medicine, depression is referred to as "Viyagula Unmatham." This study aims to evaluate the efficacy of two Siddha formulations: "Thirutharakchatha Chooranam" for internal use and "Aruganver Thylam" for external application, in treating this condition. The research also incorporates "Yogam" therapy as a complementary treatment.
Efficacy of Siddha Formulations
The clinical study demonstrated the effectiveness of the trial drugs, "Thirutharakchatha Chooranam" and "Aruganver Thylam," in alleviating symptoms of depression among patients. Utilizing the HAMILTON Depression (HAM-D) Scale, significant improvements were observed: 33.3% of participants reported good improvement, 53.3% displayed moderate improvement, and 13.3% showed mild improvement after treatment. The drugs exhibited a statistically significant reduction in HAM-D scores, indicating their potential as effective interventions for individuals suffering from "Viyagula Unmatham."
Role of Yogam Therapy
In addition to the Siddha formulations, the study included "Yogam" therapy, which addresses the holistic functioning of the body and mind through physical and mental exercises. Participants who engaged in "Yogam" alongside the trial medications reported more profound improvements in their symptoms. Specifically, the results indicated that 86.6% of those receiving combined treatment exhibited better outcomes than those who solely relied on drugs, showcasing the added benefits of integrating lifestyle changes and therapies in mental health treatment.
Significance of Holistic Approach
The findings underscore the importance of a holistic approach in treating depression, as evidenced by the positive changes in patients' psychological and emotional states when combining traditional Siddha medicine with lifestyle practices like "Yogam." Such integrative methods are not only cost-effective but also consider the individual’s overall well-being rather than merely addressing symptoms. The synergy between internal and external remedies, along with behavioral changes, highlights a potential pathway for more effective management of mental health conditions in traditional healthcare systems.
Conclusion
In conclusion, the study supports the efficacy of the Siddha drugs "Thirutharakchatha Chooranam" and "Aruganver Thylam" for treating depression, alongside the beneficial role of "Yogam" therapy. The results find that this integrative approach is effective in mitigating the effects of "Viyagula Unmatham," emphasizing the need for further research with larger patient populations to refine treatment protocols. The accessibility and affordability of these methodologies further enhance the potential for their implementation in addressing mental health challenges within the community.
FAQ section (important questions/answers):
What is the primary focus of the clinical study?
The clinical study focuses on the efficacy of Siddha drugs 'Thirutharakchatha chooranam' and 'Aruganver thylam' in treating 'Viyagula Unmatham', which is correlated with depression symptoms.
What is 'Viyagula Unmatham' in modern terms?
'Viyagula Unmatham' is primarily related to depression, characterized by symptoms such as sadness, loss of interest, low self-esteem, and sleep disturbances.
What were the observed outcomes using the HAM-D scale?
The study showed that 33.3% of patients had good improvement, 53.3% moderate improvement, and 13.3% mild improvement in their conditions after treatment.
What are the inclusion criteria for patient selection?
Patients aged 20-55 with classical features of depression, regardless of sex or religion, were included. Relevant symptoms had to be present.
How effective is 'Yogam' therapy in this study?
The inclusion of 'Yogam' therapy demonstrated significant positive results, with 86.6% of patients showing improvement when combined with the trial medications.
What is the significance of the study's findings?
The study suggests that the Siddha formulations used can effectively reduce depressive symptoms and highlights the need for further research with larger patient groups.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Study of Siddha drugs for treating depression (viyagula unmatham).”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Depression:
Depression is a mental health condition characterized by persistent sadness, loss of interest, and various emotional and physical symptoms. It affects millions worldwide, leading to significant impairment in daily functioning. Its connection with Siddha medicine is explored in the context of treatment approaches and the efficacy of traditional remedies.
2) Study (Studying):
In this context, 'study' refers to the systematic investigation of the efficacy of Siddha treatments for depression. It encompasses the methodology, patient selection, criteria for inclusion and exclusion, as well as the outcomes measured, such as the changes in HAM-D scores before and after treatment.
3) Medicine:
This term broadly encompasses all therapeutic agents used in health treatments, particularly in Siddha medicine. It refers to both traditional herbal remedies and the application of systems like diet and lifestyle changes to achieve health and well-being.
4) Siddha:
Siddha is a traditional system of medicine that originated in Tamil Nadu, India. It emphasizes a holistic approach to health, balancing physical, emotional, and spiritual well-being through herbal remedies, lifestyle practices, and body treatments. The study reflects Siddha's role in addressing mental health issues like depression.
5) Disease:
This term encompasses various health conditions, particularly focusing on psychological disorders like depression. The study aims to understand the prevalence of such diseases and their manifestations within the Indian demographic, particularly how traditional practices can provide relief.
6) Drug:
In the context of Siddha medicine, 'drugs' refer to the various herbal and mineral formulations used for treatment. The study evaluates specific preparations like 'Aruganver thylam' that provide external therapy for mental health disorders, demonstrating their role in holistic healing.
7) Observation:
Observation pertains to the systematic recording of data from patients involved in the study. It emphasizes assessing the impact of treatments over time, measuring changes in symptoms via standardized scales, and noting subjective experiences of participants during their treatment for depression.
8) Chennai:
Chennai is the capital city of Tamil Nadu, India, where the study was conducted at the National Institute of Siddha. Its significance lies in being the research hub for Siddha medicine and serving as a focal point for mental health studies in the region.
9) Siddhar:
Siddhars are revered ancient sages in Tamil literature who contributed significantly to Siddha medicine. They formulated treatments based on their spiritual insights and understandings of health, bridging the gap between traditional wellness practices and modern understanding of mental health.
10) Mud:
Mood is a significant psychological state that can be directly affected by depression. The study assesses how effective Siddha treatments can stabilize or improve patients' moods, which is crucial for overall mental health and quality of life.
11) Pur:
In this context, 'poor' signifies the inadequate improvement in patients' mental health, particularly those who do not respond favorably to the prescribed treatments. The study distinguishes between various degrees of improvement in responding patients to better tailor therapeutic approaches.
12) Male:
The term 'male' identifies one of the demographic characteristics of patients studied herein. It provides insights into the prevalence of depression among genders, revealing that in this specific study, males constituted a significant portion of participants.
13) Kalam:
The word 'kaalam' refers to seasons or specific time periods. In the context of this study, it discusses how different seasons affect mental health conditions like depression, influencing the incidence and severity of symptoms among individuals.
14) Grief:
Grief relates to the emotional response often associated with loss, which can be a contributing factor to the development of depression. The study highlights how understanding emotional responses is crucial in diagnosing and treating mental disorders.
15) Life:
Life represents the overall well-being experienced by individuals, encompassing physical, mental, and emotional health. The study aims to improve life quality through effective treatment of depression in individuals, thereby enriching their daily experiences and social interactions.
16) Inference:
Inference refers to the conclusions drawn from the data collected during the study. It emphasizes the importance of analyzing results to determine the efficacy of treatments for depression and how they could be implemented in practice for care.
17) Anxiety:
Anxiety is often comorbid with depression and represents another critical area of mental health addressed in the study. Understanding and treating anxiety symptoms alongside depression aids in providing a comprehensive approach to mental well-being.
18) Science (Scientific):
Science in this context refers to the systematic study of therapy and treatment effects, particularly how Siddha practices can be validated through research. It involves empirical data collection and analysis leading to evidence-based practices in traditional medicine.
19) Udal:
In Siddha medicine, 'udhal' refers to the physical body and its functions. The study integrates the importance of bodily health and balance in treating mental disorders, emphasizing that physical well-being significantly impacts psychological well-being.
20) Mental disorder:
Mental disorder is a broad classification that includes conditions like depression that impair normal psychological functioning. The study aims to explore effective treatment strategies within the Siddha framework specifically designed for such disorders, emphasizing their systematic management.
21) Vitiation (Vitiated):
The term 'vitiated' describes the imbalances among the body's humors in Siddha philosophy. Treatment focuses on restoring these balances to alleviate disorders; thus, therapeutic approaches aim to correct vitiated states contributing to mental illness.
22) Family:
Family plays an important role in an individual's mental health. The study recognizes that familial interactions, support systems, and histories can significantly impact the prevalence and treatment response of depression in individuals.
23) Crying:
Crying is often a symptom associated with emotional distress, particularly in depression. It emphasizes the need for treatment approaches that not only address the clinical symptoms but also provide emotional support and validation to the affected individuals.
24) Indian:
Indians refers to the demographic group participating in the study. The unique cultural, social, and economic aspects of Indian society affect mental health perspectives, making this context vital for exploring effective treatments for depression.
25) India:
India serves as the geographic and cultural context for the study. The unique traditional practices and health challenges here define the relevancy and applicability of Siddha medicine in addressing mental health issues like depression.
26) Tamil:
Tamil refers to the cultural and linguistic heritage of the state of Tamil Nadu, where Siddha medicine is rooted. This influences the practices, beliefs, and approaches to wellness embodied in the study of depression treatments.
27) Tear:
A 'tear' signifies the emotional distress individuals with depression may experience. Acknowledging these expressions is essential in understanding psychological suffering and emphasizes the necessity for adequate treatment interventions.
28) Shiva (Siva):
Dr. Siva Josyaa is the primary author of the study, representing the research effort in Siddha medicine for mental health. His insights and findings are pivotal in exploring the treatment efficacy of Siddha drugs for depression.
29) Zingiber officinale:
Zingiber officinale, commonly known as ginger, is referenced in the study as an ingredient used in Siddha formulations. It highlights the significance of herbal ingredients in traditional medicine, particularly concerning potential health benefits and therapeutic properties.
30) Mental health:
Mental health reflects the cognitive and emotional well-being of individuals. This study emphasizes its importance alongside physical health and promotes exploration of traditional therapies for enhancing mental resilience and addressing disorders like depression.
31) Human body:
The human body in Siddha medicine is viewed as a complex system where physical and mental aspects are intertwined. Treatments target the holistic well-being of individuals, acknowledging the connection between the body's states and psychological health.
32) Tirumular (Thiru-mular, Thirumular):
Thirumoolar, a significant Siddhar, contributed to the philosophical and practical foundations of Siddha medicine. His teachings and texts provide insights into the treatment of various ailments, including mental health issues, explored in the context of this study.
33) Discussion:
Discussion refers to the interpretation of the study's findings in relation to existing literature and clinical observations. It underscores the relevance of results and how they contribute to understanding the broader implications of effective mental health treatments.
34) Agasthiyar:
Agasthiyar is another revered Siddhar known for his contributions to Siddha medicine. His teachings inform the practices and treatment methodologies focused on addressing both physical and mental health in individuals, underlining traditional wisdom within the study.
35) Education:
Education highlights the importance of awareness and knowledge dissemination regarding mental health. The study emphasizes educating communities about Siddha treatments for depression and exploring traditional remedies as viable options for mental health care.
36) Attending:
Attending refers to the act of seeking medical care or support for mental health issues. The study highlights that many individuals struggle with this, reflecting on societal stigma and the barriers faced when addressing psychological disorders.
37) Salvation:
Salvation represents the ultimate goal of Siddha medicine aimed at achieving holistic well-being. This connects to the desire for relief from mental health issues like depression, fostering a sense of peace and balance in life.
38) Akattiyar:
Agathiyar, a prominent Siddhar, is pivotal in the context of Siddha philosophy and medicines. His teachings laid the foundation for many practices incorporated in the treatment approaches explored in this study, connecting traditional wisdom with contemporary needs.
39) Teraiyar:
Theraiyar refers to another influential Siddhar who contributed to the understanding of psychological ailments and their remedies within Siddha medicine. His insights are integral for exploring traditional methodologies addressing mental health concerns.
40) Tanjavur:
Tanjavur is a region in Tamil Nadu known for its rich cultural heritage, including Siddha medicine. The recognition of its historical context emphasizes the traditional practices that influence contemporary approaches to mental health treatments.
41) Nature:
Nature encompasses the environmental and inherent qualities of individuals and their surroundings that influence mental health. The study recognizes that lifestyle factors intertwined with natural elements can significantly affect psychological well-being.
42) Reason:
Reason pertains to the understanding of causative factors associated with mental disorders. It emphasizes the importance of recognizing underlying issues that contribute to depression, leading to more effective intervention strategies in Siddha medicine.
43) Botany:
Botany plays a crucial role in Siddha medicine, involving the study of plants and their medicinal properties. Understanding various herbs and their applications is essential for developing effective treatments for conditions like depression.
44) Pittam (Pittham):
Pitham is one of the three humors in Siddha medicine, representing metabolic processes. An imbalance in this humor can lead to various physical and mental health issues, hence the focus on restoring equilibrium in treatments for depression.
45) Ratna:
Ratna symbolizes preciousness or value, potentially alluding to the invaluable nature of traditional remedies in the study. It emphasizes the worth of Siddha treatments and their role in addressing significant health concerns.
46) Water:
Water, as a fundamental element in Siddha philosophy, signifies its importance in balancing bodily humors and processes. Proper hydration and its implications on health are acknowledged, especially within the treatments investigated for mental health.
47) Sugar:
Sugar may refer to dietary factors that can influence mood and emotional states. The study recognizes that dietary habits, including sugar consumption, can correlate with mental health conditions, guiding dietary recommendations alongside treatments.
48) Table:
Table refers to organized data representations showing results and statistical analyses derived from the study. It is a crucial element for conveying clinical findings effectively, allowing for clearer interpretation of the study’s outcomes.
49) Death:
Death, in the context of this study, may relate to the severe consequences of untreated mental health disorders like depression, including the risk of suicide. Emphasizing the importance of timely intervention highlights mental health's critical nature.
50) Visit:
Visit indicates the action of patients seeking treatment or follow-up for their mental health conditions. It underscores the importance of accessibility to healthcare services and the role of support networks in managing mental health.
51) Earth:
Earth symbolizes stability and grounding in the Siddha philosophy, representing the physical aspect of health and life. It emphasizes the link between physical well-being and mental clarity, a concept explored in the treatments discussed.
52) Blood:
Blood signifies the bodily fluid crucial for life, often examined in health conditions. In the study's context, assessing hematological parameters is essential to diagnose and monitor the overall health of participants undergoing treatment.
53) Caru:
Charu relates to herbal decoctions or traditional preparations in Siddha medicine. It emphasizes the significance of incorporating specific herbal concoctions in therapeutic strategies for mental health, particularly depression treatments.
54) Vali:
Vali is one of the three humors in Siddha medicine, associated with bodily movement and energy. Its vitiation can impact mental clarity and emotional equilibrium, making it critical to restore balance in mental health treatments.
55) Mana:
Mana refers to the mind in Siddha philosophy. The focus on mental health therapies underlines its importance in achieving overall well-being, making the connection between psychological health and physical treatment fundamental in Siddha practices.
56) Inji:
Inji, or ginger, is referenced in traditional medicinal preparations and is notable for its health benefits. Its inclusion reflects the reliance on herbal remedies in Siddha practices, contributing to physical and mental health management.
57) Diet:
Diet relates to nutritional factors affecting mental and physical health. The study recognizes that dietary habits can influence the effectiveness of treatments for mental disorders, including depression, guiding recommendations towards healthier practices.
58) Sign:
Sign refers to the clinical manifestations of depression explored in the study. Recognizing these signs is vital for accurate diagnosis and effective treatment within the Siddha framework, emphasizing patient care and understanding.
59) Fire:
Fire in Siddha philosophy symbolizes transformation and metabolism. Its balance is critical for maintaining overall health, affecting both physical and mental conditions, and highlights the interconnectedness of bodily functions.
60) Ghi (Ghee):
Ghee, or clarified butter, is utilized in Siddha formulations for its health benefits and medicinal properties. It illustrates how dietary components are integrated into treatment regimens for enhancing mental health and wellness.
61) Yugi (Yuki):
Yugi refers to adept practitioners or experts within the Siddha system, signifying the importance of knowledge and expertise in administering treatments. It emphasizes the role of trained professionals in providing effective care for mental health conditions.
Other Science Concepts:
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