Pharmacognosy and purification of jaypalbeej (Croton tiglium) seeds.
Journal name: World Journal of Pharmaceutical Research
Original article title: Pharmacognosy of jaypalbeej with pharmaceutical study of shodhana process (purification) of jaypal beej(croton tinglium l seed)
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Dr. Arati Abhaykumar Shinde, Dr. Yadunath C. Waykole and Dr. Ashwin A. Shete
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Pharmacognosy of jaypalbeej with pharmaceutical study of shodhana process (purification) of jaypal beej(croton tinglium l seed)
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr20195-14674
Copyright (license): WJPR: All rights reserved
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Summary of article contents:
Introduction
The study conducted by Shinde et al. focuses on the pharmacognosy and purification process known as Shodhana of Jaypal Beej (Croton tiglium L. seed), a substance categorized as Upavisha, which is less toxic compared to other toxic materials. The paper emphasizes the significance of Shodhana, an Ayurvedic detoxification process, in ensuring the efficacy and safety of medicinal preparations derived from potentially toxic substances. It outlines that Jaypal Beej is utilized in various Ayurvedic formulations and requires careful identification and purification to enhance its therapeutic properties. The study presents a systematic approach to verifying the pharmacognosy of Jaypal Beej through standard operating procedures (SOP).
The Importance of Shodhana Process
The Shodhana process, highlighted in the research, is a crucial step in Ayurveda for detoxifying toxic drugs prior to their medicinal use. Different classical texts, particularly the Rasa Tarangini, describe the Shodhana process for Jaypal Beej using Cow’s milk (Godugdha) for three cycles. This traditional method ensures the removal of toxic constituents and the improvement of the drug’s therapeutic qualities. By employing easily accessible materials and adhering to established practices, these methods can effectively mitigate the risks associated with using incomplete or improperly processed Ayurvedic medicines, thus safeguarding consumer health.
Pharmacognosy and Authentication
The paper details the pharmacognostic evaluation of Jaypal Beej, which includes both macroscopic and microscopic studies. The research identifies key morphological characteristics of the seeds, such as their oblong shape, cinnamon-brown color, and oily taste. Furthermore, the microscopic analysis provides insights into the internal structure of the seed, revealing specific cell types and their compositions. These detailed examinations confirm the identity of Jaypal Beej, which is vital for ensuring the quality and efficacy of Ayurvedic medicines derived from it.
Preliminary Analysis of Shodhana Effects
The findings indicate significant changes in the physical and chemical properties of Jaypal Beej before and after the Shodhana process. Authenticity tests revealed that the moisture content, total ash value, and water-soluble extractives decreased in the seeds post-Shodhana. Observations showed that the color of the seeds transformed from yellowish-brown to dark brown, and their inherent acrid smell lessened, suggesting effective detoxification. The study also outlines procedural steps and materials used in the Shodhana process, reinforcing its validity through practical experimentation and observation.
Conclusion
In conclusion, the research illustrates the importance of the Shodhana process in ensuring the safe and effective use of Jaypal Beej in Ayurvedic medicine. The authentication methodologies and subsequent analyses post-Shodhana demonstrate that traditional practices can be systematized to produce reliable and consistent results. These findings contribute to the broader understanding of Ayurvedic pharmacology, emphasizing the need for rigorous evaluation and standardization of herbal drugs to promote health and well-being. The study lays a foundation for further investigation into the therapeutic applications of Jaypal Beej and other Upavisha substances.
FAQ section (important questions/answers):
What is Shodhana in Ayurvedic medicine?
Shodhana is an Ayurvedic detoxification procedure that improves the pharmaceutical qualities of drugs, particularly those considered toxic or less toxic. It involves purification methods to make substances safe for medicinal use.
What is Jaypal Beej and its significance?
Jaypal Beej, or Croton tinglium L seed, is categorized as an Upavisha, or less toxic drug, used in developing various Ayurvedic preparations. Its proper identification and purification via Shodhana is essential for safe use.
What are the medicinal uses of Jaypal Beej?
Jaypal Beej is indicated in numerous Ayurvedic formulations such as Ichchhabhedi Rasa, Chandramrut Rasa, and Mahamrutyuanjaya Rasa, targeting various health maladies in different bodily systems.
How is the Shodhana process conducted for Jaypal Beej?
The Shodhana process involves boiling Croton tiglium seeds in Cow's milk three times, allowing detoxification. Seeds are immersed in the milk using a small bag, boiled, and allowed to dry between sessions.
What changes occur in Jaypal Beej after Shodhana?
After Shodhana, Jaypal Beej exhibits a change in color from yellowish-brown to dark brown. Also, physical studies show a decrease in moisture content, total ash value, and water-soluble extractives.
What are the chemical constituents of Croton tiglium seeds?
Chemical constituents of Croton tiglium seeds include fatty fixed oils, tiglic acid, croton oil, various other acids, and proteins containing toxic albumoses, among which is croton-albumin resembling ricin.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Pharmacognosy and purification of jaypalbeej (Croton tiglium) seeds.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Shodhana (Sodhana):
Shodhana is a crucial Ayurvedic process of purification and detoxification, essential for transforming toxic substances into safer, usable forms for medicinal purposes. It enhances the drug's pharmaceutical qualities, ensuring the safety and efficacy of the medicinal preparations made from plants, which may contain inherently toxic components.
2) Godugdha:
Godugdha refers to cow's milk, which is used as a medium in the Shodhana process. In Ayurvedic traditions, it is believed to possess purifying properties that help in the detoxification of potentially harmful substances like Jaypal Beej. Its incorporation in the purification process aids in enhancing the final product's safety.
3) Filling (Filled):
Filled pertains to the cellular makeup of the Jaypal Beej seeds. This term describes the process of examining the seeds microscopically, which reveals that cells such as those in the endosperm contain oil globules. These attributes are significant for understanding the seed’s medicinal properties and preparation processes.
4) Water:
Water serves two primary functions: it is an essential solvent for carrying out the Shodhana process and is used in the autenticating step when dealing with the seeds. In traditional practices, hot water is employed to soften tough seed coverings, facilitating subsequent observation and extraction of biologically relevant compounds.
5) Rasa (Rasha):
Rasa refers to the category of Ayurvedic medicines prepared from various toxic and less toxic substances, including those derived from Jaypal Beej. These formulations leverage the beneficial properties of their primary constituents while ensuring safety through rigorous processing like Shodhana, attesting to the practice's holistic approach to health.
6) Croton tiglium:
Croton tiglium, commonly known as Jaypal Beej, is a plant whose seeds possess significant medicinal properties but can be toxic if used improperly. Understanding its pharmacognosy is essential, as the seeds are employed in various Ayurvedic formulations after undergoing a meticulous detoxification process called Shodhana.
7) Observation:
Observation in the context of this study refers to the detailed examination of the morphological and microscopical characteristics of Jaypal Beej. This step is crucial in the authentication phase to ensure proper identification and assessment of effective pharmaceutical qualities that follow throughout the Shodhana process.
8) Milk:
Milk, specifically cow's milk (Godugdha), plays an essential role in the Shodhana process, where it is used as a medium for purifying Jaypal Beej. The interaction between the seeds and milk aids in reducing toxicity, thereby enhancing the seeds' usability in Ayurvedic medicine while ensuring safety.
9) Drug:
Drugs, in the context of this research, pertain to the medicinal preparations derived from processed plant materials such as Jaypal Beej. The rigorous Shodhana process employed enhances the safety profile and therapeutic potential of these drugs, ensuring they can be effectively used to treat various diseases.
10) Study (Studying):
The study represents the systematic investigation into the pharmacognosy of Jaypal Beej and its Shodhana process. The research aims to authenticate the plant sample and document its physical and chemical properties post-purification, thereby contributing to the traditional knowledge and modern understanding of Ayurvedic practices.
11) Visha (Visa):
Visha refers to highly toxic substances that can be harmful to human life. In Ayurveda, understanding Visha is critical as certain drugs originate from toxic plants. The processes for modification, such as Shodhana, ensure that these substances can be transformed into safe medicinal preparations.
12) Pune:
Pune is a city in India that hosts various educational and research institutions, including Dr. D Y Patil College of Ayurved and Research Centre, where this study was conducted. The location offers a rich cultural backdrop for Ayurvedic practices and pharmacological studies, enhancing collaboration and learning.
13) Cotton:
Cotton is utilized in the Shodhana process as a cloth to encapsulate the Jaypal Beej seeds during the immersion in Godugdha. This practical application exemplifies traditional methods in Ayurveda, where readily available materials facilitate essential purification processes, contributing to the safety and efficacy of herbal drugs.
14) Patil:
Patil refers to Dr. D Y Patil, the institution associated with the authors and their research. This name symbolizes the academic environment fostering advancements in Ayurvedic studies. The institution emphasizes integrating traditional knowledge with modern scientific approaches in the pharmaceutical field.
15) Dolayantra (Dola-yantra, Dolayamtra):
Dolayantra is a traditional apparatus used in Ayurveda for boiling substances in the Shodhana process. It ensures controlled heating and facilitates the infusion of medicinal properties from materials like Jaypal Beej into the purifying medium (Godugdha), thus playing a vital role in the formulation process.
16) Pungent:
Pungent refers to the strong, sharp smell that is characteristic of certain substances, including Jaypal Beej. Understanding the sensory properties of medicinal materials is crucial in Ayurveda, as they can influence therapeutic indications and patient acceptability while providing insights during the examination processes.
17) Vidhi:
Vidhi represents the systematic approach or protocol outlined in Ayurvedic texts for carrying out medical procedures, including Shodhana. Adherence to these traditional guides ensures that practitioners can effectively detoxify substances like Jaypal Beej, ultimately guaranteeing the safety and efficacy of the medicinal preparations.
18) Acrid:
Acrid describes the sharp, biting taste that can be associated with certain medicinal plants like Jaypal Beej before purification. Recognizing such qualities is important in Ayurveda, as they not only help in identifying the substances but also hint at their effects on health once properly processed.
19) Purification:
Purification refers to the process of detoxifying and enhancing the medicinal qualities of drugs in Ayurveda. Specifically, in this study, Shodhana of Jaypal Beej exemplifies how purification can modify toxic components into safer, more beneficial forms for therapeutic use in holistic medicine.
20) Substance:
A substance denotes any material used within Ayurvedic practice, especially those that require careful handling due to their toxic nature. For Jaypal Beej, for example, understanding the characteristics of this substance facilitates the implementation of effective detoxification through methods like Shodhana.
21) Ayurveda (Ayus-veda):
Ayurveda is an ancient system of medicine that focuses on holistic health and the utilization of natural substances for healing. This study is rooted in Ayurvedic principles, showcasing how traditional practices, like Shodhana, remain relevant in ensuring the preparation of safe and effective medicines.
22) Upavisha (Upavisa):
Upavisha refers to less toxic substances in Ayurveda that, while harmful in their natural forms, can be processed into safe medicines. Jaypal Beej is classified as Upavisha and demonstrates the importance of Shodhana in transforming potentially toxic materials into therapeutic agents.
23) Disease:
Disease indicates specific health issues that Ayurveda seeks to address through its practices. The use of Jaypal Beej in certain formulations underscores the necessity of purification through Shodhana to reduce toxicity while maximizing therapeutic efficacy in treating various ailments.
24) Powder:
Powder represents the final form of Jaypal Beej after the Shodhana process and serves as a crucial pharmaceutical preparation for use in Ayurvedic formulations. The characteristics of the powder, post-processing, influence its efficacy and application in traditional medicine.
25) Khala:
Khala is a traditional grinder used in Ayurveda for grinding herbs or seeds into fine powders. In the study, it played a significant role in preparing the powdered form of Jaypal Beej, facilitating its use in further formulations after the purification process is completed.
26) Arati:
Arati refers to Dr. Arati Abhaykumar Shinde, the lead author of this research. Her expertise and contributions to the study highlight the importance of academic research in Ayurveda, bridging traditional knowledge with scientific validation of herbal medicine practices for improved health outcomes.
27) Table:
Table in this context refers to the structured data presentation that summarizes important observations, findings, or measurements related to the study. It serves to facilitate understanding and comparison of various attributes before and after the Shodhana process.
28) Human body:
The human body is the ultimate target for Ayurvedic treatments. Understanding how substances like Jaypal Beej interact with the body—particularly when toxic in their natural state—highlights the importance of purification processes such as Shodhana to ensure safe and effective therapeutic use.
29) Dhanvantari (Dhanvamtari):
Dhanvantari is a revered figure in Ayurveda, considered the god of medicine. He symbolizes the wisdom and traditional knowledge of herbal practices. The institution associated with the study honors this heritage by advancing research in Ayurvedic pharmaceuticals to enhance healthcare practices.
30) Rasashastra (Rasa-shastra, Rasasastra):
Rasashastra is a branch of Ayurveda focusing on the study of metals, minerals, and herbo-mineral preparations for medicinal use. It embodies the ancient knowledge of detoxifying and purifying substances, emphasizing their proper utilization in patient treatments, as seen in the study of Jaypal Beej.
31) Discussion:
Discussion refers to the analytical section of the research where findings are interpreted in light of existing knowledge. It critically examines the impact of the Shodhana process on Jaypal Beej and its implications for pharmacognosy in Ayurveda, supporting ongoing advancements in traditional medicine.
32) Container:
The container is involved in the preparation and purification processes of substances like Jaypal Beej. It refers to the equipment—or dolayantra—used to hold the ingredients during the Shodhana process, ensuring effective boiling and immersion, which are critical for safety in medicinal preparations.
33) Cinnamon:
Cinnamon, as a reference to the seed color, symbolizes the organoleptic properties to recognize and validate the identity of Jaypal Beej. This coloration helps differentiate it from other seeds, emphasizing the importance of visual assessment in the larger framework of herbal pharmacognosy.
34) Dravanti (Dravamti):
Dravanti is another name for Jaypal, highlighting its various cultural and medicinal representations within Ayurveda. Knowing its names and properties illustrates the plant's significance in Ayurvedic literature and practice, particularly as an Upavisha requiring careful processing for medicinal use.
35) Mineral:
A mineral is an inorganic substance studied within Ayurveda, known for its therapeutic qualities. Understanding the impact of mineral-based medicines involves evaluating their inherent properties and how purification processes can alter their effectiveness, similar to procedures applied to plant-derived substances like Jaypal Beej.
36) Pottali:
Pottali refers to a small bag made from cotton cloth, used to contain the Jaypal Beej sample during the Shodhana process. It illustrates practical traditional techniques employed in Ayurveda, showcasing how materials are manipulated to enhance purification while ensuring that beneficial properties are preserved.
37) Surface:
Surface refers to the outer layer of the Jaypal Beej that must be detached during purification. Understanding surface characteristics is vital in the Shodhana process, as the outer layer can contain harmful compounds; effectively removing it ensures the safety of the processed seeds.
38) Animal:
Animal in this context refers to the use of animal-derived substances, particularly in the formulation of Ayurvedic medicines. The study highlights cow’s milk as a purifying medium, exemplifying the integration of animal products in undergoing detoxification processes for plant-based medicinal components.
39) Tantra (Tamtra, Tantrism):
Tantra refers to the systematic body of knowledge or methodology within Ayurveda that encompasses various practices and principles. This structured approach is critical for understanding the processing of toxic substances and ensuring their safe utilization in medicinal formulations, as reflected in the study of Jaypal Beej.
40) Indian:
Indian reflects the cultural and historical roots of Ayurveda, a system of medicine that originates from India. The significance of regionally sourced plants, practices, and philosophy in Ayurvedic studies underscores the importance of understanding traditional medicine as integral to health care in India.
41) Karma (Karman):
Karma in Ayurvedic terms refers to the actions and processes that result in particular outcomes, particularly regarding health and treatment. Understanding the karmic effects of purification processes highlights Ayurveda's holistic approach to healing, where each step significantly impacts the final therapeutic efficacy.
42) Udara:
Udara refers to abdominal or digestive system conditions addressed through Ayurvedic medicine. The significance of this term lies in the context of formulations like Ichchhabhedi Rasa, which, derived from ingredients like Jaypal Beej, illustrates how specific drugs target distinct bodily systems in Ayurvedic practice.
43) Varga:
Varga refers to a classification within Ayurveda that groups similar substances based on their properties or effects. In the context of Jaypal Beej as an Upavisha, understanding the Varga aids in determining its medicinal applications and safety precautions required for effective treatment protocols.
44) Cutan:
Sudan refers to a reagent used to stain sections in microscopic studies to identify oil globules in the Jaypal Beej seeds. The staining process is significant in revealing the internal structures of the seeds for authentication and understanding their potential medicinal properties.
45) Mala:
Mala refers to impurities or waste products in the human body, and it is connected to the detoxification properties of substances like Jaypal Beej. Understanding how Ayurvedic principles define and treat Mala aids in comprehensively addressing health issues through natural means.
46) Kasa (Kasha):
Kasa refers to respiratory diseases or conditions affecting the lungs, highlighting the therapeutic applications of Jaypal Beej in formulations targeting this system. The usage of Upavisha in addressing respiratory issues showcases Ayurvedic medicine's specific focus on various bodily ailments through targeted treatments.
47) Fire:
Fire represents the energy source used during the cooking and purification processes in Ayurveda. Its application in heating materials to ensure effective Shodhana highlights traditional methods that harness elemental forces to enhance the healing properties of medicinal substances.
48) Life:
Life refers to the ultimate objective of Ayurvedic medicine, which is to promote health and longevity. The careful processing of substances like Jaypal Beej through Shodhana illustrates the continuous effort to ensure that the medicines developed contribute positively to overall well-being and quality of life.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Pharmacognosy and purification of jaypalbeej (Croton tiglium) seeds.’. Further sources in the context of Science might help you critically compare this page with similair documents:
Pottali, Dolayantra, Godugdha, Rasatarangini, Croton tiglium, Microscopic study, Shodhana process, Ayurvedic preparation, Organoleptic study, Visha and Upvisha, Chemical constituent.