Physico-chemical and hptlc studies of rosa damascena mill
Journal name: World Journal of Pharmaceutical Research
Original article title: Physico-chemical and hptlc studies of rosa damascena mill
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
This page presents a generated summary with additional references; See source (below) for actual content.
Original source:
This page is merely a summary which is automatically generated hence you should visit the source to read the original article which includes the author, publication date, notes and references.
Tamanna Nazli, Abdul Raheem, Sadaf Subhani, Shoeb Ahmad Ansari and Rampratap Meena
Download the PDF file of the original publication
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Physico-chemical and hptlc studies of rosa damascena mill
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr20196-14377
Copyright (license): WJPR: All rights reserved
Summary of article contents:
Introduction
Rosa damascena, commonly known as “Gulab” or “Gul-e-surkh,” is a hybrid species belonging to the Rosaceae family, particularly significant for its ornamental and medicinal properties. This study investigates the physico-chemical and phytochemical standards of this plant, revealing its pharmacological attributes alongside concerns regarding safety through heavy metal and pesticide residue analysis. The findings contribute to the identification of adulterants in raw materials and establish quality standards for this valuable herbal medicine.
Importance of Phytochemical Analysis
The study conducted a comprehensive phytochemical analysis of R. damascena, highlighting the presence of essential organic compounds and secondary metabolites relevant for health benefits. Noteworthy constituents include flavonoids, tannins, and phenolics, which have been linked to various pharmacological activities such as antioxidant, anti-inflammatory, and antibacterial properties. These phytochemicals play a crucial role in traditional medicine, used in remedies for ailments ranging from digestive issues to respiratory problems, showcasing the plant's versatility in therapeutic applications.
Physico-Chemical Characteristics
The physico-chemical assessment revealed key metrics of R. damascena that suggest its potential utility and safety. Findings indicate an 11.8% moisture content, 3.2% ash, and the presence of significant amounts of alcohol and water-soluble extractives, which underscore the plant's richness in polar compounds. The study established that these compounds, identifiable through given physico-chemical parameters, can contribute crucial data for distinguishing genuine herbal products from adulterated ones.
Safety Evaluation
The study further emphasized safety aspects through detailed analysis of heavy metals and pesticide residues. Results showed that heavy metals such as lead, cadmium, mercury, and arsenic were found within permissible limits, suggesting that the plant is safe for consumption. Additionally, aflatoxins and various pesticide residues were either undetected or below the detectable limits, reaffirming the safety profile of R. damascena in traditional medicine applications, leading to a reassurance of its non-toxic nature.
Conclusion
In summary, the investigation into R. damascena has provided valuable insights into its medicinal properties through phytochemical, physico-chemical, and safety evaluations. The presence of beneficial phytochemicals, supported by favorable safety assessments, underscores its importance in herbal medicine and its potential as a quality drug. The standardized analysis not only benefits herbal practitioners in ensuring product authenticity but also adds to the body of knowledge necessary for the safe utilization of this renowned plant in traditional therapeutic practices.
FAQ section (important questions/answers):
What is the significance of Rosa damascena in herbal medicine?
Rosa damascena is valued for its numerous medicinal properties, including antibacterial, anti-inflammatory, and antioxidant effects. It is widely used in traditional remedies and modern cosmetic products due to its healing and soothing qualities.
What methods were used for the chemical analysis of Rosa damascena?
The study performed various physico-chemical analyses, including total ash, acid insoluble ash, and extractive values. Additionally, the study utilized HPTLC for phytochemical fingerprinting and evaluated heavy metals, aflatoxins, and pesticide residues for safety.
What were the findings regarding heavy metals in Rosa damascena?
The analysis showed that lead, cadmium, mercury, and arsenic levels in Rosa damascena were within permissible limits as per WHO guidelines, suggesting the plant is safe from heavy metal contamination in the environment.
What are the major chemical constituents found in Rosa damascena?
Major constituents identified include terpenes, glycosides, flavonoids, and phenolic compounds, which are responsible for the plant's therapeutic properties, including antioxidant, anti-inflammatory, and antimicrobial effects.
How was the microbial load of Rosa damascena assessed?
Microbial load analysis revealed a total bacterial count of 200 cfu/g and total fungal count of 100 cfu/g, with no presence of harmful pathogens such as Escherichia coli and Staphylococcus aureus.
What was the conclusion of the study on Rosa damascena?
The study established quality standards for Rosa damascena through comprehensive analysis, ensuring identification and differentiation from adulterants, thus supporting its safe use in herbal medicine and commercial products.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Physico-chemical and hptlc studies of rosa damascena mill”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Powder:
Powder refers to the form in which dried petals of Rosa damascena were processed for analysis. In herbal medicine, powdered substances are essential for extracting active components from plant material, enabling the evaluation of various properties like pharmacological activity and quality control. This form increases the surface area for solvents during extraction.
2) Table:
Table constitutes a method of organizing and presenting data in a structured manner. In pharmaceutical research, tables summarize findings, such as physical-chemical properties, microbial load, heavy metal content, and phytochemical analysis results, allowing for quick reference, comparison, and clarity while communing crucial information to readers and researchers.
3) Water:
Water is a polar solvent used in the extraction of hydrophilic compounds from Rosa damascena. In this context, water's role includes the solubilization of various phytochemical components, fostering their analysis. It is also significant for studying medicinal plants as it reflects their solubility characteristics, contributing to the understanding of their therapeutic potentials.
4) Phytochemical:
Phytochemical describes a category of bioactive compounds derived from plants, such as flavonoids and terpenes, that exhibit potential health benefits. The study of phytochemicals in Rosa damascena focuses on analyzing their presence, concentration, and pharmacological activities, contributing to evidence-based applications in herbal medicine and enhancing therapeutic insights.
5) Study (Studying):
Study signifies the systematic investigation of the properties and effects of Rosa damascena. Research in this context is crucial for establishing quality standards, identifying active compounds, and validating ancient medicinal practices. Studies help refine applications and assure efficacy while contributing to scientific literature surrounding herbal medicines and their pharmacological impacts.
6) Drug:
Drugs denote chemical substances that can affect bodily functions. In the context of herbal medicine, understanding the drugs derived from Rosa damascena is vital for validating their therapeutic properties, ensuring safe practices, and potentially leading to the discovery of new pharmaceuticals that enhance treatment for various conditions.
7) Pesticide:
Pesticides are substances used to eliminate pests that may contaminate medicinal plants. The analysis of pesticide residues in Rosa damascena ensures the safety and quality of the herbal product. Ensuring that pesticide levels are within permissible limits is essential for consumer health and maintaining the integrity of herbal medicine.
8) Medicine:
Medicines constitute the various formulations or compounds derived from plants like Rosa damascena intended for therapeutic use. The research seeks to validate the medicinal properties of these herbal medicines by establishing safety and effectiveness, thus supporting their role in holistic health approaches and traditional healing practices.
9) Delhi:
Delhi, the capital city of India, serves as a key location for herbal medicine study and research institutions like the Central Council for Research in Unani Medicine. Its status enhances collaboration among scientists, herbalists, and policymakers, facilitating advancements in traditional medicine and supporting local industries focused on natural products.
10) New Delhi:
New Delhi, as an administrative and political hub, plays a significant role in healthcare policy and research. The presence of numerous research bodies and educational institutions fosters innovation in herbal medicine, including studies on Rosa damascena, thereby contributing to the standardization and promotion of effective treatment modalities within the healthcare system.
11) Flavonoid:
Flavonoids are a class of phytochemicals found in many plants, including Rosa damascena, known for their antioxidant properties. This study emphasizes the importance of flavonoids' presence in the flower, correlating them with potential health benefits and therapeutic applications, solidifying their role in both traditional and contemporary medicine practices.
12) Pharmacological:
Pharmacological pertains to the study of drug action and therapeutic potentials. This research delves into the pharmacological activities of Rosa damascena, examining how its bioactive components interact with biological systems to elicit health benefits. Understanding these mechanisms is crucial for validating its traditional use and enhancing evidence-based medicine.
13) Observation:
Observation in scientific research involves the careful study and recording of phenomena and results during experiments. It is a critical step in validating hypotheses about Rosa damascena’s properties and effects. Accurate observations lead to reliable data, aiding in the thorough evaluation of the plant’s qualities and its applications in medicine.
14) Toxicity:
Toxicity refers to the degree to which a substance might be harmful. This study examines the safety profile of Rosa damascena by analyzing heavy metals and aflatoxins. Understanding the toxicity ensures that the use of the plant is safe and effective, aligning with health regulations and consumer safety standards.
15) Species:
Species indicates a group of organisms that can interbreed. In this research, Rosa damascena is recognized as a distinct species within the Rosaceae family. Understanding its classification helps in studying its unique characteristics and potential therapeutic benefits, as well as distinguishing it from other related plants in herbal research.
16) Family:
Family in botanical taxonomy groups related species. The Rosaceae family includes Rosa damascena and encompasses various plants with significant pharmaceutical properties. This classification supports the understanding of genetic relationships, potential applications, and shared characteristics among members, guiding further research and therapeutic application in natural products.
17) India:
India has a rich history of using herbal medicine, making it a vital region for studying plants like Rosa damascena. The country’s diverse flora and traditional practices contribute to the discovery of new drugs. Research in Indian contexts is significant for preserving herbal knowledge and supporting sustainable practices in medicine.
18) Fever:
Fever is a common symptom that indicates illness. Rosa damascena's traditional use for alleviating fever exemplifies its medicinal potential. Understanding its effects and validating its therapeutic properties through scientific study is essential to integrate such herbal treatments into modern healthcare practices as complementary options for managing symptoms.
19) Straw:
Straw refers to the color observed in the powdered extracts or preparations from Rosa damascena when analyzed under various conditions. It is part of the qualitative observations during testing. Identifying physical characteristics like color helps in the authentication of herbal products and ensures consistency in quality control.
20) Shada (Sada, Sadas):
Sada may refer to one of the authors involved in the research or could indicate a traditional or local medicinal term. In a broader sense, recognizing contributors in research highlights collaborative efforts in studying Rosa damascena, ensuring transparency, and supporting the acknowledgment of intellectual contributions in scientific discourse.
21) Pain:
Pain management is a significant aspect of healthcare. Rosa damascena is traditionally used for its soothing properties, potentially alleviating various types of pain. Understanding its composition and effects through scientific studies can validate these traditional uses and enable incorporation into modern pain relief strategies and practices.
22) Pharmacology:
Pharmacology is the study of drugs and their effects on the body. The research into Rosa damascena aligns with pharmacology by examining its active components and therapeutic effects. A solid pharmacological foundation is essential for developing effective herbal medicines and ensuring proper usage and safety for patients.
23) Performance:
Performance in this context refers to the efficacy and capability of Rosa damascena in producing desired medicinal effects or outcomes. Research on its bioactive compounds seeks to assess how well the drug performs in therapeutic settings, enabling comparison against conventional treatments and enhancing its application in integrative medicine approaches.
24) Discussion:
Discussion is the section of research where findings are analyzed and contextualized. The discussion on Rosa damascena findings involves interpreting the data collected from studies, evaluating the relevance of results, and comparing them with existing literature. This critical analysis supports further understanding and potential applications of the plant's medicinal properties.
25) Irritation:
Irritation refers to the adverse reactions that may occur due to the use of certain substances. Evaluating the irritation potential of Rosa damascena and its extracts is essential for informing consumers about safety and guidelines while utilizing the plant for therapeutic purposes, thereby ensuring informed choices and healthy practices.
26) Science (Scientific):
Science represents the systematic study of the natural world, underlining the methodologies behind researching Rosa damascena. The application of scientific principles ensures that findings are credible, contributing to enhanced understanding of herbal therapies, and fostering a basis for integrating traditional and modern medicinal practices.
27) Substance:
Substance encompasses any material with a defined composition. In the study, substances address the chemical components found in Rosa damascena that contribute to its medicinal properties. Analyzing these substances allows researchers to evaluate potency, efficacy, and the potential therapeutic benefits for various health conditions.
28) Phoenicia:
Phoenicia refers to the historical region associated with the cultivation of Rosa damascena. Understanding this connection enriches the historical context of the plant and its uses, revealing the significance of flora in cultures and traditional practices, thereby identifying patterns of use and knowledge across civilizations.
29) Relative:
Relative can refer to the familial relation among various species, as well as the comparison of their effects within the same family. When studying Rosa damascena, understanding relatives helps in identifying potential therapeutic benefits, shared compounds, and characteristics that may influence different medicinal applications.
30) Disease:
Disease indicates a pathological condition that can be treated or alleviated by medicinal substances like Rosa damascena. The quest for solutions through herbal medicines underscores the necessity of rigorous research in identifying potential remedies as substitutes or complements to conventional therapy, expanding treatment options for various diseases.
31) Quality:
Quality refers to the standard of the Rosa damascena flowers and their extracts concerning safety and efficacy. Assessing quality through physico-chemical methods and regular testing ensures that the herbal products maintain high standards for consumers, fostering trust and reliability in therapeutic applications.
32) Company:
Company refers to the business entities involved in the procurement, production, or sale of herbal medicines. The relationship of companies with traditional products like Rosa damascena promotes industry growth while also ensuring that the quality and efficacy of sourced products are maintained for consumer safety.
33) House:
House represents a place or environment where Rosa damascena might be grown or used. Understanding its connection to domestic settings fosters appreciation for traditional uses, promoting community health engagement while highlighting the significance of plants in various cultural and healing practices.
34) Khari (Kha-ri):
Khari may refer to Khari Baoli, a famous market in Delhi known for spices and herbs. This location emphasizes the cultural and commercial significance of traditional herbal medicines like Rosa damascena, enhancing accessibility and promoting the use of herbal products in contemporary health practices.
35) Glass:
Glass may refer to the equipment used in the extraction processes or analysis of plant samples in research. Glass apparatus is crucial for maintaining sterile conditions, thus ensuring accurate results in experiments, making it an essential material for laboratory work in botanical and pharmaceutical studies.
36) Sugar:
Sugar could refer to a component analyzed during the physico-chemical studies of Rosa damascena. Understanding the sugar content can reveal insights into the plant’s sweetness, nutritional value, and fermentation properties, contributing valuable information about its potential uses in food and medicinal applications.
37) Hindi (Himdi):
Hindi can relate to the cultural context of the research, indicating the local language spoken in regions where Rosa damascena is utilized. Recognizing this language reinforces the significance of cultural practices in herbal medicine and the importance of local knowledge in the effective use of traditional remedies.
38) Genu:
Genu may refer to the genus but is often either a typographical error or shorthand for genus; it emphasizes the classification level within the biological taxonomy. This classification aids in identifying morphological and chemical similarities among plants, fostering a deeper understanding of their applications in medicine and agriculture.
39) Food:
Food relates to the nutritional aspects of Rosa damascena, indicating its incorporation in culinary practices. This highlights the dual-use of the plant in both nutrition and medicine, promoting a holistic view of health that integrates diet, herbal remedies, and culinary practices for improved well-being.
40) King:
King often refers to the royal status attributed to Rosa damascena as a valuable and revered plant. Designated as 'king of flowers,' it symbolizes its cultural and historical significance, underlying its prominence in traditional practices, perfumes, cosmetics, and healthcare across different cultures and regions.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Physico-chemical and hptlc studies of rosa damascena mill’. Further sources in the context of Science might help you critically compare this page with similair documents:
Medicinal properties, Essential oil, Heavy metal analysis, Pesticide residue, Physico-chemical parameters, Phytochemical analysis, Fluorescence Analysis, Microbial load analysis, Total phenolic content, High performance thin layer chromatography (HPTLC), Volatile oil, Tannin, Authentication of plant material, Unani medicine, Chemical constituent, Physico-chemical studies, Rosa damascena Mill, Aflatoxin analysis.