Efficacy of homeopathy for adolescent acne: a randomized trial.

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Journal name: World Journal of Pharmaceutical Research
Original article title: Effectiveness of homoeopathic medicines in cases of acne vulgaris in adolescence – a randomized controlled trial
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Original source:

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Author:

Dr. Shrimohan Sharma and Dr. Rajni Devi


World Journal of Pharmaceutical Research:

(An ISO 9001:2015 Certified International Journal)

Full text available for: Effectiveness of homoeopathic medicines in cases of acne vulgaris in adolescence – a randomized controlled trial

Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research

Doi: 10.20959/wjpr20197-15136

Copyright (license): WJPR: All rights reserved


Download the PDF file of the original publication


Summary of article contents:

Introduction

Acne vulgaris is a widespread skin disorder primarily affecting adolescents and young adults, characterized by the presence of comedones, papules, pustules, and potential scarring. It is estimated to affect approximately 9.4% of the global population and can lead to significant social and psychological repercussions, especially among adolescents who may experience issues such as anxiety, depression, and social withdrawal. This study aimed to evaluate the effectiveness of individualized Homoeopathic medicines compared to a placebo in treating acne vulgaris, using the Global Acne Grading System (GAGS) as a measurement tool.

Effectiveness of Homoeopathic Medicines

The study involved 60 participants aged 11 to 20 years, randomly divided into two groups: one receiving individualized Homoeopathic treatments and the other receiving a placebo. The Homoeopathic treatment group showed significant improvement, with 27 out of 30 patients demonstrating at least mild improvement, as assessed using the GAGS scale. Specific remedies like Natrum muriaticum, Calcarea sulphurica, and Sulphur were commonly prescribed. In stark contrast, the placebo group showed minimal improvement, with 14 patients remaining status quo, highlighting that individualized Homoeopathic treatments are significantly more effective than placebo in managing acne vulgaris.

Demographics and Prevalence

The study found that acne vulgaris predominantly affected males (61.66%) between the ages of 18 and 20. The majority of participants were from urban areas (56.67%) and belonged to middle socioeconomic status (61.66%). The findings align with other studies that indicate a similar peak prevalence in the teenage years, suggesting that various socioeconomic and geographical factors may influence the occurrence and the perception of acne, making it more common in urban dwellers with specific lifestyle habits.

Severity of Acne and Treatment Response

The severity of acne amongst participants varied, with moderate acne being most prevalent in 46.67% of cases. Types of lesions included papulopustular eruptions as the most common. Family history also played a significant role, with 58.33% of participants having a familial background of acne, thereby indicating a genetic predisposition to the disease. This information emphasizes the complexity of acne vulgaris's etiology, where both hereditary and environmental factors may contribute to its manifestation and severity.

Conclusion

In conclusion, this study provides compelling evidence that individualized Homoeopathic medicines significantly improve the clinical manifestations of acne vulgaris compared to placebo treatment. The findings underscore the importance of considering alternative therapeutic options for acne management, particularly in young populations who may be vulnerable to its psychological and social impacts. Although limited by a small sample size, this research opens avenues for more extensive studies to further explore the efficacy of Homoeopathic treatments for acne vulgaris on a larger scale.

FAQ section (important questions/answers):

What is the primary objective of the study on Acne vulgaris?

The study aims to assess the effectiveness of individualized Homoeopathic medicines compared to placebo in treating cases of Acne vulgaris in adolescents, using the Global Acne Grading System (GAGS) for evaluation.

What was the demographic of the patients involved in the study?

A total of 60 adolescents aged 11 to 20 years, with acne vulgaris symptoms, were enrolled in the study and randomly assigned to either the Homoeopathic treatment group or the placebo group.

What were the main findings of the treatment with Homoeopathic medicines?

In the treatment group, 27 out of 30 patients showed improvement, with significant effectiveness observed in acne management compared to the placebo group, which had a majority of patients remaining unchanged.

Which Homoeopathic medicines were most commonly prescribed in the study?

Natrum muriaticum, Calcarea sulphurica, and Sulphur were the most frequently prescribed medicines for patients in the Homoeopathic treatment group.

What kind of study design was implemented in this research?

The study was designed as a randomized, single-blind, placebo-controlled trial to ensure the reliability and validity of the results in assessing treatment effectiveness.

What were the limitations mentioned in the study?

The primary limitation was the small sample size, which may restrict the generalizability of the findings. A larger sample size could provide broader insights into the effectiveness of treatments for Acne vulgaris.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Efficacy of homeopathy for adolescent acne: a randomized trial.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Medicine:
Medicines in this context refer to the specific homeopathic remedies prescribed to patients with acne vulgaris. The study details individualization based on symptomatology, reflecting the homeopathic principle that treatment should be tailored to the person's unique health condition, aiming for effective symptom relief and recovery.

2) Study (Studying):
The study represents a systematic investigation aimed at assessing the effectiveness of homeopathic treatment for acne vulgaris in adolescents. This randomized controlled trial provides empirical data, methodologies, and outcomes that are critical for understanding the therapeutic potential and clinical relevance of individualized homeopathic interventions in dermatology.

3) Devi:
Devi refers to Dr. Rajni Devi, one of the primary investigators in the study. Her role is important as it reflects the involvement of qualified practitioners in conducting the research, lending credibility and expertise to the study's methodology, data analysis, and interpretation of results in homeopathic treatment applications.

4) Table:
Table in this context pertains to the organized data presentations that summarize the findings from the research. Tables facilitate clear comparisons of pre- and post-treatment scores, statistical analyses, and group results, providing a visual understanding of the study's outcomes related to acne vulgaris treatment effectiveness.

5) Disease:
Disease denotes the pathological condition being studied, specifically acne vulgaris. Understanding acne as a prevalent skin disorder is crucial, as it impacts many individuals, particularly adolescents. The objective of the study is to evaluate alternative treatments for this widespread condition and assess their effectiveness against conventional methodologies.

6) Jaipur:
Jaipur is the location where the study was conducted, specifically at a homoeopathic medical college and research center. The geographical context is significant because it reflects the cultural and demographic factors that may influence acne prevalence, treatment choices, and the acceptance of homeopathy within the local population.

7) Antibiotic (Antibacterial):
Antibiotics are conventional medical treatments commonly used for various infections, including acne. This term is relevant to the study as it highlights the shortcomings associated with long-term antibiotic use, such as side effects and resistance, thereby justifying the exploration of homeopathic alternatives for acne management.

8) Rajasthan:
Rajasthan is the Indian state where the study occurred. The socioeconomic and cultural factors specific to Rajasthan, including common dietary practices, healthcare access, and population characteristics, may influence the findings of the study, underscoring the need for localized approaches in medical research and treatment.

9) Male:
Male refers to the gender demographic that was predominantly affected by acne vulgaris in the study. Understanding the differences in prevalence and severity of acne between males and females is essential for tailoring treatment approaches and addressing gender-specific psychosocial impacts associated with the condition.

10) Observation:
Observation is a critical methodological component in the study, indicating the systematic monitoring and recording of patient outcomes throughout the treatment process. Accurate observations ensure reliable data collection, enhancing the validity of conclusions drawn regarding the effectiveness of homeopathic medicines for acne vulgaris.

11) Perception:
Perception relates to how patients view their acne condition and the emotional and psychological impacts associated with it. The study emphasizes the importance of understanding patient perception, as it influences treatment adherence, overall satisfaction, and how individuals cope with the social stigma of acne vulgaris.

12) Depression:
Depression is highlighted as a psychological consequence of acne vulgaris, often affecting patients’ mental health and quality of life. The investigation addresses the interconnectedness of acne and mental health issues, indicating a need for comprehensive treatment plans that include psychological support for affected individuals.

13) Suffering:
Suffering refers to the physical and emotional distress experienced by individuals with acne vulgaris. This term underscores the importance of effectively managing acne not just for cosmetic reasons, but also to alleviate the significant psychosocial burdens that accompany the disorder, enhancing overall well-being.

14) Relative:
Relative in this context refers to the familial or genetic relationship regarding a history of acne vulgaris. Understanding relatives' experiences with the condition can provide insights into genetic predisposition and can significantly impact an individual’s perception, anxiety, and treatment motivations.

15) Anxiety:
Anxiety signifies a common emotional issue associated with acne vulgaris, often affecting youths due to aesthetic concerns and social pressures. The study highlights the need to address anxiety in treatment plans, as managing acne effectively may also alleviate related psychological distress.

16) Family:
Family pertains to the essential unit of social structure that significantly impacts individuals with acne vulgaris. Support from family can be crucial in managing the emotional effects of acne, as family dynamics and perceptions can either exacerbate or alleviate the associated psychological challenges.

17) Rajni:
Rajni refers to Dr. Rajni Devi, contributing significantly to the study as a co-author and researcher involved in evaluating the effectiveness of homeopathic treatments. Her involvement emphasizes the importance of qualified practitioners in grounding research findings in clinical expertise and patient care.

18) India:
India is the country of focus in this study, which investigates the prevalence and treatment of acne vulgaris in an Indian population context. Recognizing cultural specifics, socioeconomic conditions, and healthcare beliefs within India is vital for tailoring effective treatment strategies for acne management.

19) Anger (Angry):
Anger represents an emotional response that can arise from the social stigma and psychological impacts of acne vulgaris. The study acknowledges anger as a potential emotional side effect of acne, highlighting the necessity for holistic treatment approaches that address both physical and emotional health.

20) Drug:
Drugs refer to conventional pharmaceutical treatments traditionally prescribed for conditions like acne vulgaris. Understanding the limitations and side effects of these drugs justifies exploring alternative treatment methods, such as homeopathy, as a viable option for managing acne in the patient population.

21) Life:
Life denotes the overall quality of existence that can be significantly affected by conditions like acne vulgaris. Effective treatment may lead to improved emotional and social functioning, making the study of its management crucial for enhancing the quality of life in affected individuals.

22) Mental health:
Mental health relates to the psychological well-being of individuals suffering from acne vulgaris. The study highlights the interrelation between dermatological conditions and mental health, indicating that effective treatment of acne can have beneficial effects on patients’ overall mental health and emotional stability.

23) Inflammation:
Inflammation signifies the body's biological response indicative of acne vulgaris. Understanding the inflammatory processes involved in acne development is essential for developing effective treatments aimed at reducing symptoms and preventing scarring associated with these inflammatory lesions.

24) Discussion:
Discussion involves the interpretation of study results, reflecting on the findings’ implications within the context of existing literature. This section is vital for drawing conclusions about the effectiveness of homeopathic treatments in comparison to placebo, providing insights for further research and clinical practices.

25) Varanasi (Varanashi):
Varanasi is referenced as a comparative geographical location where similar studies on acne vulgaris have been conducted. The cultural and environmental factors specific to Varanasi can provide a valuable context for analyzing differences in acne prevalence and treatment approaches across different regions in India.

26) Swelling:
Swelling describes the physical manifestation of inflammation associated with acne lesions. Acknowledging this symptom is crucial for understanding the clinical presentation of acne vulgaris, which can drive treatment decisions and help in assessing patient responses to homeopathic interventions.

27) Pregnant:
Pregnant refers to the exclusion criteria in the study that highlights the importance of not including pregnant women in the trial. This consideration is crucial to avoid any risks associated with homeopathic treatments during pregnancy, ensuring the safety of both mother and child in research.

28) Quality:
Quality denotes the standard of life and well-being affected by acne vulgaris. The study recognizes the need to improve patients’ quality of life by providing effective treatment options that minimize both physical symptoms and the psychological implications related to acne.

29) Burning (Burn, Burned, Burnt):
Burning refers to one of the potential side effects related to conventional acne treatments or the condition itself. Understanding this aspect is essential for addressing patient discomfort and ensuring that treatment regimens, including homeopathy, consider and mitigate such symptoms.

30) Sharman (Sarma, Sharma, Sarman):
Sharma signifies Dr. Shrimohan Sharma, the primary investigator in the study. His expertise and involvement in researching the effectiveness of homeopathic medicines lend authority to the findings and underscore the importance of professional guidance in health-related investigations.

31) Indian:
Indian pertains to the cultural and demographic context of the study population, emphasizing the relevance of local healthcare practices, beliefs, and treatment modalities. Such factors play a crucial role in understanding the acceptance and effectiveness of homeopathic treatments for acne vulgaris.

32) Visit:
Visit signifies an individual patient’s appointment for consultation or treatment as part of the study protocol. Structured visits provide opportunities for healthcare professionals to assess treatment efficacy, adjust interventions as necessary, and cultivate patient-provider relationships for better outcomes.

33) Kali:
Kali refers to Kali bromatum, a specific homeopathic remedy mentioned in the study as one of the medicines prescribed for treating acne vulgaris. Understanding the role of specific homeopathic remedies is essential for evaluating their efficacy and appropriateness in individualized patient care.

34) Food:
Food signifies the dietary components that may influence acne development and severity. The study implicates diet as a potential environmental factor, suggesting the need for holistic approaches to acne treatment that integrate dietary considerations alongside medicinal interventions.

35) Diet:
Diet denotes the nutritional habits that may contribute to the onset or exacerbation of acne vulgaris. Recognizing the role of diet in managing acne highlights the importance of comprehensive treatment plans that include lifestyle and dietary modifications along with homeopathic remedies.

36) Meat:
Meat is mentioned as part of dietary considerations that may affect acne prevalence. The study suggests that high consumption of certain food types, including meat, might correlate with increased acne, emphasizing the need for further investigation into the role of diet in skin health.

37) Sign:
Sign indicates observable manifestations or symptoms of acne vulgaris that are critical for diagnosis and assessment in the study. Recognizing various signs of the condition helps inform treatment strategies and evaluate the effectiveness of interventions over time.

38) Hair:
Hair refers to the hair follicles that are central to the pathophysiology of acne vulgaris. Understanding the relationship between hair follicles and acne development aids in comprehending the mechanistic factors involved in the condition and addressing its treatment effectively.

39) Road:
Road can symbolize the location of the study, specifically Station Road in Jaipur where the research took place. Geographical and environmental factors associated with a specific road or neighborhood can influence the healthcare-seeking behavior and treatment modalities related to acne.

40) Pur:
Poor signifies the socioeconomic status of certain patient groups involved in the study. Understanding the impact of socioeconomic conditions on health access and treatment options is crucial for developing equitable healthcare strategies and addressing disparities in acne vulgaris management.

Other Science Concepts:

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Discover the significance of concepts within the article: ‘Efficacy of homeopathy for adolescent acne: a randomized trial.’. Further sources in the context of Science might help you critically compare this page with similair documents:

Adolescent, Socioeconomic status, Age-group, Randomized controlled trial, Placebo group, Acne vulgaris, Individualized treatment, Psychosocial impact, Global Acne Grading System, Homoeopathic medicine, Moderate form of acne, Histories of acne vulgaris, Indicated Medicine.

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