Comparative screening of two hibiscus species with phytochemical studies.

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Journal name: World Journal of Pharmaceutical Research
Original article title: Comparative screening of two hibiscus species by monographic, phyto chemical including biological studies
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Original source:

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Author:

C. Lavanya Vasavi, A. Siva Jyothi, P. Sravani, T. Pranav Chand, S. K. Adil, Dr. R. Ramasubramania Raja and Dr. K. Harinadha Baba


World Journal of Pharmaceutical Research:

(An ISO 9001:2015 Certified International Journal)

Full text available for: Comparative screening of two hibiscus species by monographic, phyto chemical including biological studies

Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research

Doi: 10.20959/wjpr20197-14945

Copyright (license): WJPR: All rights reserved


Summary of article contents:

Introduction

The research conducted by C. Lavanya Vasavi et al. aims to standardize two species of hibiscus, namely Hibiscus cannabinus and Hibiscus sabdariffa, through pharmacognostical and phytochemical analyses, along with evaluating their larvicidal activities. The study is particularly relevant in the context of controlling mosquito larvae, especially in areas like Nellore, India, where open drainages allow for the easy proliferation of mosquito larvae. Given the increasing reliance on herbal solutions for medicinal purposes in both developed and developing countries, this research seeks to contribute foundational knowledge for future studies in herbal medicine.

Phytochemical Composition and Extraction Process

One key concept explored in this research is phytochemical composition and extraction methods. The study employed a soxhlet extraction apparatus using ethanol as a solvent to obtain crude extracts from both hibiscus species. The yield of the extracts was reported as 7.040g for Hibiscus cannabinus and 7.140g for Hibiscus sabdariffa. Comprehensive tests were performed to identify various bioactive compounds, including flavonoids, alkaloids, steroids, saponins, and tannins, each contributing to the plants' therapeutic properties. The presence of these compounds suggests potential medicinal applications, particularly in herbal formulations.

Pharmacognostical Screening

Another significant aspect of the study is the pharmacognostical screening carried out on the two hibiscus species. This screening included macroscopical and microscopical evaluations, fluorescence analysis, and physicochemical testing. The microscopical evaluation revealed key structural features, such as the presence of vascular bundles, epidermal layers, and calcium oxalate crystals. Parameters like extractive values, moisture content, and crude fiber content were also determined, establishing detailed profiles of both plants. This extensive standardization not only aids in the identification and classification of plant materials but also enhances the reliability of using these herbs in traditional medicine.

Larvicidal Activity Evaluation

The evaluation of larvicidal activity represents a crucial part of the research. The researchers tested the effectiveness of the ethanolic extracts against the larvae of Aedes mosquitoes at varying concentrations (10mg/ml to 160mg/ml) and observed mortality rates over different time intervals (6 to 72 hours). The results indicated that Hibiscus sabdariffa exhibited greater potency against mosquito larvae compared to Hibiscus cannabinus, showcasing its potential as a natural pesticide. This is particularly significant considering the ongoing concerns regarding the harmful effects of synthetic pesticides on non-target organisms and the environment.

Conclusion

In conclusion, the research underscores the importance of standardization and evaluation of herbal plants, specifically Hibiscus cannabinus and Hibiscus sabdariffa, in the context of pharmacognosy and their applications in mosquito control. The findings contribute valuable insights into the phytochemical constituents, pharmacognostical characteristics, and bioactivity of the two hibiscus species. Given the rising interest in herbal medicine as a safer alternative to allopathic treatments, this study may serve as a vital resource for future researchers and practitioners seeking effective, natural solutions, especially in regions where affordability of healthcare is a concern. The successful application of these findings could lead to broader utilization of herbal remedies in pest control and medicinal practices.

FAQ section (important questions/answers):

What was the objective of the research conducted on Hibiscus species?

The research aimed to standardize the leaves of Hibiscus cannabinus and Hibiscus sabdariffa using pharmacognostical and phytochemical parameters, along with assessing their larvicidal activities against Aedes mosquito larvae.

What pharmacognostical screening methods were used in the study?

The study used macroscopical evaluation, microscopical parameters including transverse section analysis, fluorescence analysis, and physicochemical parameters to characterize the Hibiscus species thoroughly.

How was the phytochemical composition of the Hibiscus leaves analyzed?

Phytochemical screening involved the extraction and identification of various bioactive compounds like flavonoids, alkaloids, tannins, and saponins from the leaf extracts of both Hibiscus species.

What were the findings regarding larvicidal activity against mosquito larvae?

Hibiscus sabdariffa showed greater larvicidal potency against Aedes mosquito larvae compared to Hibiscus cannabinus, indicating its potential for natural mosquito control.

Why was the study conducted in Nellore, India?

Nellore provided easy access to Aedes mosquito larvae due to open drainages, making it an ideal location for measuring the larvicidal efficacy of the herb extracts.

What is the significance of herbal medicines according to the research?

The research highlights the rising interest in herbal medicines as safe alternatives to allopathic treatments, particularly for populations with limited access to conventional healthcare in developing countries like India.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Comparative screening of two hibiscus species with phytochemical studies.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Drug:
The term 'Drug' typically refers to a chemical substance that is used in the treatment, diagnosis, prevention, or alleviation of disease. In the context of herbal studies, drugs can be derived from plant materials, signifying the importance of understanding their properties, efficacy, and safety profile for medicinal use.

2) Raja:
Raja, in this context, refers to Dr. R. Ramasubramania Raja, a key author of the study. His involvement underscores the significance of scholarly contributions to research, particularly in pharmacognosy and herbal medicine, highlighting how experts in the field propel understanding of plant-based pharmaceuticals.

3) Activity:
In the study, 'Activity' connotes the biological effects evaluated, specifically the larvicidal activity against Aedes mosquitoes. Understanding bioactivity is crucial in assessing the effectiveness of herbal extracts, thereby informing potential applications in pest control and public health management, particularly in tropical regions.

4) Table:
Tables in scientific literature serve to present data succinctly and clearly, allowing for efficient comparison of results. In this study, tables summarize findings related to various extracts, chemical tests, and larvicidal activity, thus providing an organized visualization of complex data sets in pharmacognostical research.

5) Water:
Water is often used as a solvent in phytochemical extractions, highlighting its role in the solubilization of polar compounds. In the context of the study, understanding water's efficacy as an extracting medium helps in evaluating the bioactive constituents of the investigated Hibiscus species for medicinal properties.

6) Pharmacognostical:
Pharmacognostical refers to the study of medicines derived from natural sources, particularly plants. It encompasses the identification, characterization, and evaluation of plant materials for medicinal use, thus emphasizing the critical role of phytochemistry and botany in discovering and standardizing herbal remedies.

7) Powder:
In herbal medicine, 'Powder' typically refers to the processed form of plant material used in extractions and studies. The grinding of leaves into a powder is essential for maximizing surface area for solvent extraction, impacting the efficacy and concentration of active compounds analyzed in the study.

8) Phytochemical:
Phytochemicals are bioactive compounds produced by plants that contribute to their medicinal properties. Understanding phytochemicals, like flavonoids or alkaloids, is vital in pharmacognosy, facilitating the discovery of natural remedies and toxicological studies, thus informing potential therapeutic applications and health benefits.

9) Medicine:
Medicines refer to any substance used for medical treatment. The study encompasses various types of medicines derived from plants, emphasizing the importance of researching natural therapeutic agents and their potential role in healthcare, particularly in regions where access to conventional medicine is limited.

10) India:
India represents a significant context for the study of herbal medicine due to its rich biodiversity and traditional medicinal practices. The research underscores the need for accessible healthcare solutions in developing nations, showcasing how local plants like Hibiscus can provide therapeutic options for the population.

11) Oil:
In herbal studies, 'Oils' can signify fixed oils or essential oils derived from plant materials. These compounds often have therapeutic properties, serving various medicinal purposes. Their extraction and analysis clarify their contributions to the efficacy of herbal formulations in treating health conditions.

12) Jute:
Jute is a fibrous plant often associated with textile production rather than medicinal use. However, its inclusion in the research highlights the multifaceted nature of plants like Hibiscus can influence economic and agricultural practices alongside their medicinal properties, particularly in developing countries.

13) Narayana (Nara-ayana, Nara-yana):
Narayana refers to Narayana Pharmacy College, the institution associated with the study. The college’s involvement illustrates the academic context in which the research is conducted, advocating for the exploration of pharmacognosy and fostering education on the medicinal plants prevalent in the region.

14) Species:
The term 'Species' identifies distinct groups of organisms, essential in botanical studies for classification. The identification of Hibiscus cannabinus and Hibiscus sabdariffa species in the research signifies their unique medicinal properties and the necessity for species-specific investigations in phytotherapy.

15) Family:
In botanical classification, 'Family' denotes a higher taxonomic rank that groups related plants. Understanding the Malvaceae family, to which both Hibiscus species belong, is crucial for appreciating their shared characteristics and potential synergistic effects within their phylogenetic context in alternative medicine.

16) Medium:
In the context of this study, 'Medium' refers to the solvent or growth environment used during experiments. The choice of medium for larvicidal assays is pivotal in determining the effectiveness of plant extracts, impacting the understanding of their practical applications in pest control.

17) Ghana:
Ghana, along with other African nations, is contextually relevant to the study of Hibiscus species, as these plants may have historical uses in traditional medicine. Understanding their utilization in Ghana reflects broader cultural practices and the potential for integrating indigenous knowledge into contemporary healthcare strategies.

18) Fever:
'Fever' is a common symptom of many diseases, often treated with various medications. Exploring the medicinal properties of Hibiscus species offers potential natural remedies for the treatment of fever and related ailments, further emphasizing the importance of ethnopharmacological studies in herbal medicine.

19) Developing:
'Developing' refers to countries with lower economic statuses. The focus on herbal therapies like the studied Hibiscus species highlights their critical role in providing affordable healthcare solutions in developing nations, serving populations unable to access expensive allopathic medicine.

20) Substance:
'Substance' generally refers to a particular kind of matter. In pharmacological studies, it indicates specific compounds in plant extracts that exhibit biological activity, thus crucial for identifying the active components responsible for the therapeutic effects of herbal remedies.

21) Flavonoid:
Flavonoids are a significant class of phytochemicals found in various plants, known for their antioxidant and anti-inflammatory properties. Their exploration in the study of Hibiscus species underscores the importance of these compounds in developing natural medicines and their potential health benefits.

22) Pesticide:
The term 'Pesticide' refers to substances used to prevent, destroy, or control pests. In the context of this study, herbal extracts are evaluated for potential as natural pesticides, offering environment-friendly alternatives to synthetic chemicals commonly used in agriculture and public health.

23) Disease:
'Disease' signifies any abnormal condition of the body or mind, often requiring treatment. The study aims to explore how compounds from Hibiscus can address diseases prevalent in populations with limited healthcare access, thus contributing to the discourse on natural remedies in medicine.

24) Nature:
Nature refers to the physical world and its phenomena. In herbal medicine, understanding the natural origins of medicinal plants emphasizes the importance of sustainability and conservation efforts, particularly as biodiversity diminishes due to human activity and environmental changes.

25) Indian:
The term 'Indian' highlights the cultural and geographical context of the study, particularly in relation to the use of Hibiscus species in traditional Indian medicine. It underscores the relevance of indigenous knowledge in supporting the exploration of local plants for health benefits.

26) Sugar:
Sugar is a common component in various food products and has certain medicinal properties in traditional contexts. Its mention may suggest its use in formulations of herbal remedies or treatments focused on dietary considerations for managing certain diseases.

27) Cutan:
Sudan is significant in the context of this research as a historical region associated with the domestication of Hibiscus sabdariffa. Understanding the plant's origins contributes to the knowledge of its traditional uses and ecological adaptations in different cultural settings.

28) Genu:
'Genu' likely refers to a typographical error or abbreviation that requires contextual clarification. In studies, maintaining precise terminology is crucial to ensure accurate communication of scientific findings and preventing misunderstandings in the literature regarding plant classification.

29) Java:
Java is included in the discussion as a location where Hibiscus species are cultivated. Recognition of geographic variations in cultivation practices emphasizes the global distribution of plants with potential health benefits and their integration into local economies and medicinal practices.

30) Hemp:
'Hemp' in this context relates to the fibrous plant properties of Hibiscus cannabinus, known for its textile applications. The term underscores the importance of understanding the multiple uses of a single plant species, linking agricultural practices to medicinal explorations.

31) Pur:
'Poor' describes individuals or communities lacking adequate financial resources. Addressing healthcare accessibility for poor populations through herbal medicines provides an empirical basis for promoting natural products as cost-effective options for treating common illnesses in settings with limited access to modern healthcare.

32) Performance:
'Performance' refers to the effectiveness or efficiency of an intervention or study. Understanding the performance of various herbal extracts in terms of their pharmacological activities informs future research and practical applications in developing effective natural therapies for widespread health issues.

33) Discussion:
'Discussion' in research provides an analytical framework for interpreting results. It allows researchers to compare findings with existing literature, highlighting implications and potential applications of their work, while also identifying limitations and suggesting future directions for exploration.

34) Epidemic:
The term 'Epidemic' refers to a sudden increase in the number of cases of a disease above what is normally expected. Recognizing the relationship between herbal remedies and epidemic management underscores the relevance of integrating traditional medicine into public health strategies for disease control.

35) Relative:
'Relative' refers to the comparative association of different entities or concepts. In research, understanding relationships between various factors—such as extract composition and larvicidal effectiveness—enables a more comprehensive grasp of outcomes and enhances interpretative accuracy of findings.

36) Shravani (Sravani):
Sravani likely refers to one of the authors involved in the research study. Highlighting the contributions of authors establishes a collaborative environment in scientific inquiries, demonstrating how diverse expertise collectively advances the understanding of pharmacognostical and phytochemical research.

37) Animal:
In scientific contexts, 'Animal' typically refers to non-human species used in research. These organisms are crucial for preclinical studies to assess the safety profile and therapeutic potential of new compounds derived from plants in medicinal research.

38) Bombay:
Bombay (now Mumbai), as a major city in India, is historically significant for trade and cultural exchange. Its inclusion emphasizes the interconnectedness of regional practices in herbal medicine and the broader context of herbal research based on local flora.

39) Spider:
The term 'Spider' denotes a specific type of animal and highlights the broader ecological context in which natural remedies may be evaluated. Certain plants have been traditionally used to treat spider bites, showcasing the importance of ethnopharmacological knowledge and its applications in herbal medicine.

40) Insect:
'Insect' is a broad category encompassing numerous arthropods, including mosquitoes. The study highlights the relevance of examining insecticidal properties of plant extracts, offering insights into biocontrol methods against pests that pose significant public health challenges.

41) Lanka (Lamka, Lànkà):
'Lanka' refers to Sri Lanka, which is known for its diverse flora and traditional medicinal practices. The connection emphasizes the significance of regional biodiversity in contributing to the global understanding of phytotherapy and the efficacy of herbal medicines.

42) Chand:
Chand implies a contributor in the research. Acknowledging collaboration among researchers fosters a deeper understanding of knowledge generation, which is integral to advancing pharmacognostical studies focused on extracting valuable insights from indigenous plant species.

43) Hindi (Himdi):
'Hindi' recognizes the linguistic and cultural context of the research presented. Understanding local languages and folklore enhances engagement with traditional medicinal knowledge, thereby informing the development of culturally relevant healthcare practices within specific communities.

44) Cina:
China is renowned for its extensive use of herbal medicine, significantly influencing global pharmacognosy. Acknowledging its contributions highlights the cultural and historical contexts that shape the understanding and application of medicinal plants across different societies.

45) Worm:
Worm often pertains to parasitic organisms causing various health issues. The study’s exploration of herbal treatments could contribute to managing infections associated with worms, thereby adding value to the understanding of traditional medicine in addressing such health concerns.

46) Shiva (Siva):
Siva likely pertains to A. Siva Jyothi, one of the authors of the study. The recognition of each author's contribution underscores the collaborative nature of research in pharmacognosy, emphasizing the importance of teamwork in exploring plant-based therapies.

47) Shan (San):
Shan may refer to a traditional practice or indigenous knowledge related to the use of herbal medicines. Cultivating an understanding of regional practices enhances the knowledge base of pharmacognosy and informs the development of community-focused health solutions.

48) Crop:
In agricultural contexts, 'Crop' signifies cultivated plants grown for food or other uses. The cultivation of crops like Hibiscus reflects the intersection of agriculture and pharmacognosy, promoting awareness of sustainable practices that yield medicinally valuable plant resources.

49) Tai:
'Thai' recognizes the cultural heritage and traditional practices in Thailand associated with herbal medicine. Incorporating different cultural practices enriches the understanding of plant-based therapies, supporting the global quest for effective natural remedies and holistic approaches in healthcare.

50) Life:
'Life' refers to the biological essence of living organisms, including plants and humans. Exploring the relationship between plant life and medicinal properties contributes significantly to the sustainability of herbal medicine as a vital resource for improving health and well-being.

Other Science Concepts:

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Discover the significance of concepts within the article: ‘Comparative screening of two hibiscus species with phytochemical studies.’. Further sources in the context of Science might help you critically compare this page with similair documents:

Hibiscus cannabinus, Hibiscus sabdariffa, Phytochemical, Herbal medicine, Phytochemical screening, Fluorescence Analysis, Pharmacognostical Studies, Transverse section, Physicochemical Parameter, Ethanol Solvent, Aedes mosquitoes, Larvicidal activity, MICROSCOPICAL EVALUATION, Chemical test, Microscopical parameters, Macroscopical parameters.

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