Antibacterial properties of Achyranthes aspera L. against UTI pathogens.
Journal name: World Journal of Pharmaceutical Research
Original article title: Studies on antibacterial properties of achyranthes aspera l. against the pathogens of urinary tract infection.
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Original source:
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Dr. Arvind B. Patil, Dnyaneshwar Pawar and Aniket Patil
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Studies on antibacterial properties of achyranthes aspera l. against the pathogens of urinary tract infection.
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr20184-11102
Copyright (license): WJPR: All rights reserved
Download the PDF file of the original publication
Summary of article contents:
Introduction
The study conducted by Dr. Arvind B. Patil and his colleagues explored the antibacterial properties of Achyranthes aspera L., a medicinal plant commonly found in India. Given the increasing resistance of bacteria to conventional antibiotics and the reliance of a significant portion of the global population on herbal remedies, the research aimed to assess the efficacy of various extracts from the plant against multiple pathogenic bacteria responsible for urinary tract infections. The extracts evaluated included polysaccharides, lipids, alkaloids, and other compounds, with a focus on their antimicrobial activities.
Antibacterial Efficacy of Plant Extracts
One of the key findings of this study highlighted the antibacterial efficacy of various extracts obtained from Achyranthes aspera L. The research showed that polysaccharide and lipid extracts displayed significant inhibitory effects against common pathogens such as E. coli, Staphylococcus aureus, and Pseudomonas spp. The study details that polysaccharide extracts inhibited the growth of Staphylococcus aureus and Klebsiella species, while lipid extracts were effective against E. coli and Pseudomonas spp. Additionally, the crude methanolic extract also demonstrated substantial antibacterial activity, reinforcing the potential of these extracts in treating infections caused by resistant bacterial strains.
Extraction Techniques and Compound Yield
The methodology employed to extract various compounds from Achyranthes aspera also contributed to understanding its potential medicinal properties. Fresh leaves were processed using different techniques, including infusion and maceration with solvents like methanol and chloroform. The yield of extracts varied, with polysaccharides being the most abundant at 18.27% from the dried leaves. Other extracts, such as lipids and quaternary alkaloids, were also derived in notable amounts, showcasing the diverse chemical composition of the plant and its potential medicinal applications.
Traditional and Economic Significance of Medicinal Plants
The research underscores the historical and cultural significance of herbal medicine, particularly in countries like India, where a large proportion of the population relies on plant-based remedies for primary healthcare. The study references the profound heritage of traditional medicine systems, such as Ayurveda and Unani, which utilize numerous plant species for therapeutic purposes. Achyranthes aspera L. is one such plant that not only holds traditional medicinal value but also presents an economically viable alternative to expensive pharmaceuticals, especially in developing regions.
Conclusion
The exploration of Achyranthes aspera L. revealed promising antibacterial properties, making it a candidate for further research in developing alternative treatments for bacterial infections. The study illustrates the plant's high yield of bioactive compounds, which could be harnessed for therapeutic use, especially against multidrug-resistant organisms. Overall, the findings support the relevance of traditional medicinal plants in modern pharmacology and encourage additional studies to validate and exploit the full potential of Achyranthes aspera L. and similar herbal remedies.
FAQ section (important questions/answers):
What is the focus of the study on Achyranthes aspera?
The study evaluates the antibacterial properties of various extracts from Achyranthes aspera against pathogens that cause urinary tract infections, including E. coli, Staphylococcus aureus, and Pseudomonas aeruginosa.
What types of extracts were obtained from Achyranthes aspera?
Extracts including polysaccharides, lipids, polar compounds, alkaloids, quaternary alkaloids, and crude methanolic extract were obtained by infusion and maceration of the plant material.
How were the antibacterial activities measured in the study?
Antibacterial activities were measured by estimating the zones of inhibition on Mueller-Hinton agar plates after applying the extracts at a concentration of 0.5 mg/ml.
Which extracts showed maximum antibacterial effectiveness?
Polysaccharides, lipids, quaternary alkaloids, and crude methanolic extracts showed significant antibacterial effectiveness against various pathogens, particularly E. coli and Staphylococcus aureus.
Why is Achyranthes aspera significant in traditional medicine?
Achyranthes aspera is recognized for its medicinal properties and is used traditionally for its ability to treat various ailments, supporting the increasing interest in herbal medicine.
What was the conclusion regarding the antibacterial properties?
The study concluded that extracts from Achyranthes aspera, particularly lipids and quaternary alkaloids, are effective in inhibiting key urinary tract infection pathogens, signifying their potential use in treatment.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Antibacterial properties of Achyranthes aspera L. against UTI pathogens.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Patil:
Patil refers to Dr. Arvind B. Patil, a researcher involved in the study examining the antibacterial properties of Achyranthes aspera. His contributions to this research highlight the role of medicinal plants in developing alternative therapies for infectious diseases, emphasizing traditional knowledge in modern scientific inquiry.
2) Antibiotic (Antibacterial):
Antibiotics are substances used to combat bacterial infections, and the study examines how extracts from Achyranthes aspera may serve as natural alternatives. This exploration is crucial amid rising antibiotic resistance, urging the need for new therapeutic options derived from plants.
3) Aureus:
Aureus refers to Staphylococcus aureus, a common bacterium known to cause various infections, including skin and respiratory infections. The study investigates the effectiveness of Achyranthes aspera extracts against this pathogen, emphasizing the plant's potential as a natural antibacterial resource.
4) Medicine:
Medicines include a broad category of therapeutic substances. The study investigates Achyranthes aspera as a medicinal plant, aiming to validate traditional medicinal practices while considering its implications for contemporary pharmacology and drug development.
5) India:
India is significant in this research as it is rich in biodiversity and traditional medicinal practices. The study focuses on local medicinal plants, showcasing India's substantial contributions to herbal medicine and the need for studies that validate these traditional treatments scientifically.
6) Activity:
Activity refers to the biological effects exhibited by the extracts of Achyranthes aspera in inhibiting bacterial growth. Evaluating the antimicrobial activity is essential for determining the efficacy of these extracts in treating infections and their potential role in drug development.
7) Drug:
Drugs, plural, refers to various medications and their properties, including those derived from plants. This study indicates the exploration of herbal extracts as possible drug formulations, illustrating the ongoing search for effective solutions to treat infections without reliance on synthetic pharmaceuticals.
8) Table:
Table refers to data summarizing the experimental outcomes in the study. It presents results related to the extraction efficiency of various compounds from Achyranthes aspera, facilitating a clearer understanding of which extracts exhibit the strongest antibacterial properties.
9) Disease:
Disease, in the singular, refers to a specific pathological condition. The study emphasizes the impact of urinary tract infections, highlighting how herbal remedies like Achyranthes aspera may provide innovative solutions in combating such prevalent conditions.
10) Water:
Water is referenced in the extraction process of compounds from Achyranthes aspera, indicating the use of aqueous solutions to facilitate the extraction of medicinal components. Its relevance underscores the importance of safe, accessible solvents in herbal medicine preparation.
11) Pune:
Pune, a city in Maharashtra, India, is where the research was conducted. The local flora, particularly Achyranthes aspera, is studied to assess its medicinal properties. Pune’s academic institutions play a vital role in advancing research in traditional medicine and natural therapies.
12) Ayurveda (Ayus-veda):
Ayurveda is an ancient system of medicine from India that emphasizes the use of natural herbs for healing. The study’s relevance to Ayurveda highlights the significance of traditional knowledge and practices in validating the medicinal properties of plants like Achyranthes aspera.
13) Maharashtra (Maharastra, Maha-rashtra):
Maharashtra is the Indian state where the research took place, serving as a backdrop for studying locally available medicinal plants. The biodiversity of this region enhances the exploration of various herbal remedies and their potential applications in healthcare.
14) Commerce:
Commerce indicates the economic aspects of medicinal plant use and trade in extracts like those from Achyranthes aspera. Understanding the commercial potential reinforces the promise of herbal medicines in addressing public health challenges while economically benefiting local communities.
15) Species:
Species refers to the classification of organisms, and in this study, it highlights Achyranthes aspera as a species of interest. Understanding this species’ specific properties aids in classifying and researching its therapeutic potential against bacterial infections.
16) Science (Scientific):
Science encompasses the systematic study of the natural world through observation and experimentation. This study employs scientific methods to explore the antibacterial effects of Achyranthes aspera, reinforcing the integration of traditional medicine into modern scientific frameworks.
17) Forest:
Forests represent the biodiversity and natural habitats where many medicinal plants thrive. The study implies the importance of conserving these environments to ensure sustainable access to plants like Achyranthes aspera for future medicinal use.
18) Botany:
Botany is the scientific study of plants. Within the context of this research, it emphasizes the importance of understanding plant biology and chemistry to uncover the medicinal properties of species like Achyranthes aspera and their potential therapeutic applications.
19) Vidya:
Vidya means knowledge in Sanskrit, reflecting the emphasis on education and traditional learning in Ayurveda. This study highlights the importance of integrating ancient wisdom with modern scientific research to validate and utilize traditional medicinal practices effectively.
20) Road:
Road refers to the ecosystem where Achyranthes aspera is commonly found, indicating its adaptability and prevalence in various environments, including wastelands. This accessibility supports the exploration of its medicinal properties as a potential everyday remedy.
21) Ocimum sanctum:
Ocimum sanctum, also known as Tulsi, is a significant plant in Ayurvedic medicine, showcasing the diverse use of herbs in India. Its mention in the study underscores the importance of familiar medicinal plants and their applications in treating various ailments.
22) Human body:
The human body refers to the biological system affected by diseases, and the significance lies in the potential of Achyranthes aspera extracts to influence physiological health. The research aims to establish how these extracts may interact with and benefit human health.
23) Dnyaneshwar (Dnyaneshvar):
Dnyaneshwar may refer to Dnyaneshwar Pawar or another individual contributing to this research. Highlighting individuals involved in the study emphasizes the collaborative nature of scientific exploration and the importance of diverse expertise in advancing knowledge in the field.
24) Discussion:
Discussion in a scientific context refers to analyzing and interpreting the results obtained from research. This section of the study emphasizes understanding the implications of antibacterial properties of Achyranthes aspera, reinforcing its relevance in traditional medicine and future research.
25) Developing:
Developing refers to nations or regions in economic transition, where traditional remedies may provide essential healthcare solutions. The study emphasizes the need for accessible treatments for communities in developing areas, leveraging local medicinal plants to address health challenges effectively.
26) Suffering:
Suffering denotes the experience of pain or distress due to illness. This term emphasizes the importance of finding effective treatments for diseases, encouraging the investigation of natural remedies like Achyranthes aspera to alleviate pain and improve patient outcomes.
27) Vomiting:
Vomiting is a common symptom of various diseases that may require medicinal intervention. The highlighted effectiveness of Achyranthes aspera in addressing symptoms like vomiting showcases its role in traditional medicine for treating gastrointestinal disorders and maintaining overall health.
28) Vindhya (Vimdhya):
Vindhya refers to a mountain range in India, symbolizing the rich biodiversity of the country. This geographical context emphasizes the availability of various medicinal plants, highlighting regions where plants like Achyranthes aspera can be found and studied for their therapeutic properties.
29) Siddha:
Siddha is another ancient system of medicine in India, focusing on herbal and natural remedies. Mentioning Siddha emphasizes the diversity of traditional healing practices available in the country and the importance of further validating these practices through scientific research.
30) Nature:
Nature encompasses the vast array of living organisms, including medicinal plants. This term reflects the intrinsic relationship between humans and the natural world, underscoring the need to study and preserve medicinal plants like Achyranthes aspera for future health benefits.
31) Animal:
Animal refers to living organisms that may also benefit from medicinal plants. The interconnectedness of human and animal health emphasizes comprehensive research on the antibacterial properties of Achyranthes aspera, applicable across different biological systems.
32) Indian:
Indian relates to the cultural, botanical, and medicinal heritage of India, emphasizing the relevance of local knowledge in the context of this study. The Indian context highlights the rich tradition of herbal medicine and the potential for scientific validation of indigenous practices.
33) Campu:
Campu appears to be a typographical error but could refer to
34) indicating the academic or ecological context where research is conducted. It suggests an emphasis on promoting botanical studies within educational institutions for better understanding and exploration of local flora, like Achyranthes aspera. The associated research can lead to improved recognition and application of medicinal plants in health care practices.:
Kumar
Other Science Concepts:
Discover the significance of concepts within the article: ‘Antibacterial properties of Achyranthes aspera L. against UTI pathogens.’. Further sources in the context of Science might help you critically compare this page with similair documents:
Medicinal plant, Traditional medicine, Economic importance, Antimicrobial activity, Antibacterial properties, Urinary tract infection, Zones of inhibition, Herbal drug, Ayurveda and Unani, Crude methanolic extract, Tropical area, Achyranthes aspera L., Plant based drug.