Ganoderma sp. petrolatum paste for goat skin issues in Maiduguri.
Journal name: World Journal of Pharmaceutical Research
Original article title: Potential use of wild ganoderma sp based petrolatum paste against some mixed dermatological conditions in goats in maiduguri, nigeria
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Shamaki B. U., Sandabe U. K., Abdulrahman F.I., Sa’idu S. N. A., Tekdek L. B. and Ya’uba A. M.
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Potential use of wild ganoderma sp based petrolatum paste against some mixed dermatological conditions in goats in maiduguri, nigeria
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr20187-11716
Copyright (license): WJPR: All rights reserved
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Summary of article contents:
Introduction
The study conducted by Shamaki et al. (2018) explores the potential use of a petrolatum paste derived from the wild mushroom Ganoderma sp. to treat dermatological conditions in goats in Maiduguri, Nigeria. This research was motivated by the rising prevalence of skin infections, specifically Dermatophilosis caused by Dermatophilos congolensis, along with other mixed fungal organisms. The aim was to assess the efficacy of this natural remedy in treating symptoms associated with these infections in goats and to evaluate the general effectiveness of Ganoderma sp. as an alternative treatment for skin diseases that are resistant to conventional therapies.
Antimicrobial Efficacy of Ganoderma sp.
The study highlights the antimicrobial properties of Ganoderma sp., documenting its effectiveness against Dermatophilosis and other fungal infections. The experimental design included twelve adult goats afflicted with skin lesions, which were treated with petrolatum-based preparations containing varying concentrations (2.2 mg/ml, 4.4 mg/ml, and 6.7 mg/ml) of the powdered mushroom. Remarkably, all treated goats showed full recovery of skin integrity after just two weeks, significantly outperforming the control group treated with Charmil R. The presence of phytochemicals such as flavonoids, tannins, and terpenoids in the Ganoderma sp. preparation was suggested as a contributor to its antibacterial and antifungal effects, establishing it as a viable candidate for treating mixed dermatological conditions in livestock.
Properties and Analysis of Ganoderma sp.
Significant findings regarding the composition of Ganoderma sp. were also reported. The proximate analysis of the powdered mushroom revealed a high dry matter content (89.1%) alongside notable amounts of crude protein (6.3%), fiber (29.0%), and carbohydrates (46.8%). Phytochemical analysis indicated the presence of various beneficial compounds, including terpenoids and flavonoids, while some expected compounds, such as alkaloids, were absent. This comprehensive characterization of Ganoderma sp. provides foundational insights regarding its nutritional and therapeutic potential, emphasizing the importance of these natural products in developing effective treatments.
Mechanisms of Dermatophilosis Treatment
The study discusses the challenges associated with the treatment of dermatophilosis, particularly the growing concern over antimicrobial resistance. Dermatophilos congolensis has shown resistance to common antibiotics, complicating the management of this infection in goats. The successful application of Ganoderma sp. was attributed to its unique properties that address both bacterial and fungal infections simultaneously. The study advocates for natural alternatives, such as Ganoderma sp., as a means to mitigate reliance on synthetic drugs, potentially reducing the risk of resistance and adverse side effects linked to long-term antibiotic use.
Conclusion
In conclusion, the findings from this study assert the potential of wild Ganoderma sp. based petrolatum as an effective treatment for mixed dermatological infections in goats, specifically against Dermatophilosis and other fungal pathogens. The rapid recovery observed in treated animals, combined with the rich phytochemical profile of the mushroom, suggests it could serve as a sustainable alternative to traditional therapies. This research may significantly contribute to veterinary medicine by offering an accessible and affordable treatment option, further enhancing livestock health management in regions affected by such diseases.
FAQ section (important questions/answers):
What was the aim of the study on Ganoderma sp. paste?
The study aimed to investigate the efficacy of wild Ganoderma sp. based petrolatum paste against Dermatophilosis and other mixed fungal infections in goats.
How many goats were involved in the clinical evaluation?
Twelve adult goats with dermatological conditions were purchased and divided into four groups for treatment.
What concentrations of Ganoderma sp. were tested?
Concentrations of 2.2 mg/ml, 4.4 mg/ml, and 6.7 mg/ml of Ganoderma sp. were prepared for topical application in different groups.
What infections were identified in the goats studied?
The microbial analysis indicated that the infections were mainly caused by Dermatophilos congolensis, along with other fungi such as Rhyzopus oryzae and Aspergillus niger.
What were the results of using Ganoderma sp. paste?
The study found that the Ganoderma sp. based petrolatum paste effectively treated skin lesions in all treated goats, restoring skin integrity within two weeks.
Why is the use of wild Ganoderma sp. significant?
Wild Ganoderma sp. offers a natural alternative against antibiotic-resistant infections, potentially reducing prolonged treatment periods and negative side effects.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Ganoderma sp. petrolatum paste for goat skin issues in Maiduguri.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Disease:
Diseases denote pathological conditions affecting organisms. The study examines mixed dermatological diseases in goats, showcasing the prevalence and impact of skin infections caused by various microbial agents, thus highlighting the need for effective treatment options that are safe and potentially more accessible than conventional antibiotics.
2) Animal:
Animals represent a wide range of multicellular organisms, including livestock such as goats. Their health is critical in agricultural contexts, and studies like this examine the implications of treating diseases in animals for overall productivity, economic stability for farmers, and potentially zoonotic outcomes.
3) Medicine:
Medicine denotes the science and practice of diagnosing, treating, and preventing illness. The study investigates the potential of a natural remedy from Ganoderma sp. to treat skin infections in goats, emphasizing the intersection of traditional remedies with veterinary practices aimed at improving animal health.
4) Veterinary medicine:
Veterinary medicine is the branch of medicine concerned with the diagnosis, treatment, and prevention of diseases in animals. This research contributes to the field by exploring alternative treatments for skin diseases in livestock, integrating the importance of animal welfare with veterinary practices for improved health outcomes.
5) Antibiotic (Antibacterial):
Anti-bacterial refers to substances that combat bacterial growth. The study investigates the effectiveness of Ganoderma sp. as an anti-bacterial agent against pathogens causing skin infections in goats, showing the importance of finding effective treatments in veterinary practice.
6) Phytochemical:
Phytochemical signifies bioactive compounds derived from plants. This study emphasizes the analysis of phytochemicals in Ganoderma sp. such as flavonoids and terpenoids that demonstrate antimicrobial properties, highlighting the potential of plant-based treatments in veterinary medicine to address skin infections in livestock.
7) Study (Studying):
Study denotes systematic research aiming to understand specific phenomena. This research explores the effectiveness of a wild Ganoderma sp.-based petrolatum paste in treating dermatological conditions in goats, thereby providing evidence-based insights into alternative treatment options within veterinary medicine.
8) Water:
Water is a vital substance for hydration and biochemical processes in living organisms. In the context of this research, clean drinking water is essential for maintaining goat health during the study, and is typically administered ad libitum to support wellbeing and recovery from infections.
9) Powder:
Powder refers to a finely ground substance used in various applications. In this study, Ganoderma sp. was ground into powdered form to facilitate its incorporation into petrolatum paste for topical application, exploring new methods of delivering therapeutic agents for treating skin infections in goats.
10) Flavonoid:
Flavonoid is a class of phytochemicals found in many plants, known for their antioxidant and anti-inflammatory properties. The presence of flavonoids in Ganoderma sp. suggests a potential mechanism underlying its therapeutic action against skin infections, contributing to the development of natural veterinary treatments.
11) Species:
Species represent groups of organisms that can reproduce and produce fertile offspring. The study identifies wild Ganoderma species and their relevance as medicinal agents, illustrating how certain species can provide alternative therapeutic solutions for dealing with microbial infections in goats.
12) Table:
Table refers to a structured representation of data. In the study, tables summarize analytical results such as proximate and phytochemical analysis of Ganoderma sp., facilitating clear communication of findings and supporting evidence for the efficacy of the treatment developed during the research.
13) Pur:
Poor denotes a lack of quality or adequate conditions. In the study, references to poor management practices as a predisposing factor for dermatological diseases highlight the broader context of animal husbandry where disease prevalence can impact livestock health and productivity.
14) Pharmacology:
Pharmacology is the branch of medicine that studies drug action. The study aligns with pharmacological principles by evaluating the effects of a natural remedy, assessing how the phytochemical constituents of Ganoderma sp. may interact with microbial pathogens to provide therapeutic benefits.
15) Toxicology:
Toxicology is the study of the adverse effects of substances on living organisms. Although this study focuses on the beneficial effects of a natural remedy, understanding the toxicological profiles of treatments is crucial in ensuring that therapeutic agents are safe for animal use.
16) Activity:
Activity denotes the capacity to perform a function. The study evaluates the antimicrobial activity of Ganoderma sp. against various pathogens, measuring its effectiveness in treating skin infections in goats, which is essential for determining the potential of such natural treatments.
17) Blood:
Blood refers to the vital fluid transporting oxygen and nutrients in organisms. The study mentions the limited blood supply to the skin in relation to antibiotic treatment, underscoring the importance of understanding physiological aspects when developing topical remedies for skin infections in animals.
18) Cina:
China relates to the origin of equipment used in the study, like the grinding machine. The mention highlights the globalization of research resources and the utilization of various technologies in veterinary studies aimed at improving animal healthcare and disease management.
19) Bida:
Bida is referenced in the study as an author noted for discussing veterinary diseases. Citing previous works reinforces the importance of foundational literature in guiding current research efforts and establishing context in the ongoing exploration of animal health issues.
20) Dish (Dis):
Dish refers to a shallow, typically round container used in laboratories. In the study, Petri dishes are employed for microbial sample collection, emphasizing their standard use in scientific research for isolating and culturing bacteria or fungi in various experiments.
21) Container:
Container signifies any receptacle that holds substances. In the study, containers are used to transport and store Ganoderma sp. samples and microbial cultures, illustrating their role in maintaining the integrity of samples during experimentation and ensuring accurate results.
22) Farmer:
Farmer denotes individuals engaged in agricultural activities, including livestock management. The relevance to this study lies in the potential impact of effective treatments on farmers' productivity and profits, thus emphasizing the practical implications of veterinary research on agricultural economies.
23) Transmission:
Transmission denotes the transfer of pathogens from one host to another. The study implies the significance of understanding disease transmission routes in managing dermatological conditions in livestock, highlighting the necessary measures for preventing infections that can affect animal health and productivity.
24) Malnutrition:
Malnutrition refers to inadequate or imbalanced nutrition impacting health. The study addresses malnutrition's potential role in increasing susceptibility to diseases like Dermatophilosis, indicating the importance of holistic approaches to livestock care that include proper nutrition alongside medical treatment.
25) Accumulation (Accumulating, Accumulate):
Accumulation signifies the gradual gathering of substances. In the study, it discusses the reduced effectiveness of antibiotics in skin conditions due to inadequate accumulation at the target area, suggesting the need for treatments that offer sustained effective concentrations at the site of infection.
26) Measurement:
Measurement refers to the process of determining the extent, quantity, or capacity of something. In the study, precise measurements of powdered Ganoderma sp. are integral to creating effective formulations for treating skin infections in goats, relating to broader practices of dosage determination in medicine.
27) Discussion:
Discussion encompasses the interpretation of research findings. In the study, a thoughtful discussion of results helps contextualize the effectiveness of Ganoderma sp. against dermatological diseases, providing insights into the implications for veterinary treatments and guiding future research directions.
28) Developing:
Developing pertains to the process of growth or formulation. In this study, developing a petrolatum paste from Ganoderma sp emphasizes the innovative approach to creating natural remedies for skin conditions in goats, aligning with needs for sustainable and effective veterinary treatments.
29) Substance:
Substance denotes a specific kind of matter with uniform properties. The identification of certain bioactive substances within Ganoderma sp. relevant to treating skin infections in goats underscores the importance of chemical characterization in developing effective veterinary medicines.
30) Science (Scientific):
Science represents the systematic pursuit of knowledge through experimentation and observation. This study exemplifies scientific inquiry in veterinary medicine, combining empirical research methods with an exploration of the medicinal potential of natural products in treating animal diseases.
31) Aureus:
Aureus refers to Staphylococcus aureus, a bacterium noted for causing infections. In the study context, including references to this organism underlines the complexity of skin infections and the potential for multiple pathogens that could impact treatment efficacy in dermatological conditions.
32) Pushpa (Puspa):
Pushpa is likely a reference to a citation or author involved in related research. Mentioning authors like Pushpa contributes to the academic discourse on the topic, potentially introducing additional insights or evidence regarding the efficacy of natural remedies in veterinary medicine.
33) Arati:
Aarati is referenced similarly to Pushpa, likely as a contributor to veterinary research. Citing multiple authors in the context of the study helps establish a broader scientific foundation, enhancing the credibility of findings on the efficacy of phytochemicals in treating animal diseases.
34) Chang:
Chang refers to an author likely involved in the broader discussions regarding health issues, inclusive of the zoonotic implications of animal diseases. The inclusion of Chang's work emphasizes the interconnectedness of animal and human health, particularly in the context of zoonotic disease transmission.
35) Sugar:
Sugar pertains to carbohydrates that serve as an important energy source. In the study, sugar could relate to the proximate analysis of Ganoderma sp. or its role as a potential substrate for microbial growth, essential considerations for understanding its nutritional aspects and therapeutic potential.
36) Death:
Death signifies the cessation of all biological functions. Understanding the impact of untreated diseases on livestock, as outlined in the study, emphasizes the serious consequences of infection on animal health, which can ultimately lead to mortality and economic loss for farmers.
37) Fight:
Fight relates to the act of combating disease or infection. In this study's context, it illustrates the intent to fight dermatological conditions in goats using a natural remedy, indicating the role of veterinary medicine in actively seeking effective treatments for animal health issues.
38) Drug:
Drug denotes a specific active substance utilized to diagnose, cure, treat, or prevent diseases. In the context of this research, the study's exploration of a natural drug derived from Ganoderma sp. serves as a valuable investigation into alternative treatments for skin infections in animals.
39) Hand:
Hand signifies physical interaction or manipulation in tasks. In the study, it may refer to the practical aspect of applying treatments or collecting samples, highlighting the hands-on nature of veterinary research as practitioners engage directly with the animals and interventions involved.
Other Science Concepts:
Discover the significance of concepts within the article: ‘Ganoderma sp. petrolatum paste for goat skin issues in Maiduguri.’. Further sources in the context of Science might help you critically compare this page with similair documents:
Topical application, Antimicrobial Resistance, Pharmacologically active substance.