Study on genetic testing knowledge in newlyweds in Sangli Miraj Kupwad.

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Journal name: World Journal of Pharmaceutical Research
Original article title: A study to assess the knowledge and attitude towards genetic testing among the newly married couples in selected urban areas of sangli miraj kupwad corporation area
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Original source:

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Author:

Alisheeba Kalekar and Regina David Satvekar


World Journal of Pharmaceutical Research:

(An ISO 9001:2015 Certified International Journal)

Full text available for: A study to assess the knowledge and attitude towards genetic testing among the newly married couples in selected urban areas of sangli miraj kupwad corporation area

Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research

Doi: 10.20959/wjpr20189-12175

Copyright (license): WJPR: All rights reserved


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Summary of article contents:

Introduction

The research article titled "A Study to Assess the Knowledge and Attitude Towards Genetic Testing Among the Newly Married Couples in Selected Urban Areas of Sangli Miraj Kupwad Corporation Area" by Alisheeba Kalekar and Regina David Satvekar aims to evaluate the understanding and perceptions regarding genetic testing among newly married couples. The study highlights the significance of genetic disorders, which can be hereditary rather than acquired, and draws attention to the prevalence of genetic conditions in countries with high rates of consanguinity, particularly in developing nations like India.

Understanding Genetic Disorders

Genetic disorders are not caused by external factors like infections or trauma but are inherited from parents. The research reveals that substantial numbers of births each year are affected by genetic conditions, contributing to high infant mortality and health complications. For example, about 3-4% of babies are born with a genetic disease or major birth defect, with 1% suffering from chromosomal abnormalities. The study notes that specific conditions like thalassemia, hemophilia, and Down syndrome are prevalent in the Indian population, exacerbated by the high rates of consanguinity observed in many communities, increasing the risk of autosomal recessive disorders.

The Importance of Genetic Testing

Genetic testing plays a crucial role in identifying hereditary conditions and helping expectant parents make informed decisions about family planning. The study emphasizes that such tests can confirm or rule out genetic disorders and assist in detecting potential complications in unborn children. It elaborates on various genetic testing methods available, including molecular, chromosomal, and biochemical tests. Despite its benefits, decisions regarding genetic testing remain complex and personal, and cultural attitudes toward it can vary significantly among populations.

Demographic Variations in Knowledge and Attitude

The research explores the demographics of newly married couples and their knowledge and attitudes towards genetic testing. The study involved 150 couples and analyzed factors such as age, sex, and education level. Findings revealed that a significant portion of participants had average knowledge (59.6%) about genetic testing, while a vast majority (89.7%) displayed a positive attitude towards it. Interestingly, age emerged as the only demographic variable significantly associated with knowledge levels, indicating an overall trend where older individuals possessed greater awareness of genetic testing.

Conclusion

The study concludes that enhancing general awareness and understanding of genetic testing is vital for the newly married couples to support informed reproductive choices. Encouraging educational initiatives and public health programs could help bridge the knowledge gap and address the socio-economic challenges posed by genetic disorders. As genetic testing becomes increasingly pivotal in modern healthcare, fostering a positive attitude towards such testing will be essential to mitigate the impacts of genetic conditions on families and society at large.

FAQ section (important questions/answers):

What is the main objective of the study on genetic testing?

The study aims to assess the knowledge and attitude towards genetic testing among newly married couples and to explore associations with demographic variables.

What are genetic disorders and how are they inherited?

Genetic disorders are conditions inherited from parents through genes, which can manifest at birth or develop later. They include congenital abnormalities and genetic diseases caused by mutations.

What role does genetic testing play in public health?

Genetic testing helps identify inherited conditions, assess risks, and guide family planning decisions, significantly impacting the prevention of genetic disorders and the overall health of the population.

What were the demographics of the study participants?

The study included 150 newly married couples, equally split between men and women, predominantly aged between 24 to 29 years, with the majority having received lower education levels.

How did knowledge and attitude towards genetic testing correlate?

The study found a low positive correlation between knowledge and attitude scores regarding genetic testing, indicating that improved knowledge could enhance attitudes toward genetic testing.

What is the significance of the study's findings?

The findings highlight the necessity for educational programs to improve awareness about genetic testing, which may ultimately lead to better health decisions among newly married couples.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Study on genetic testing knowledge in newlyweds in Sangli Miraj Kupwad.”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Knowledge:
Knowledge refers to the awareness and understanding of genetic testing and its implications among newly married couples. It encompasses their familiarity with genetic disorders, testing methods, and the importance of genetic counseling, which can significantly impact family planning and health decisions, particularly in the context of heritable conditions.

2) Disease:
Diseases, particularly those of genetic origin, pose a significant health challenge worldwide. Awareness and understanding of genetic diseases are crucial for effective public health strategies, enabling communities to reduce the impact of inherited conditions and improve overall health outcomes through proactive measures like screening and education.

3) Study (Studying):
The study is a research initiative aimed at assessing knowledge and attitudes regarding genetic testing among newly married couples. It aims to provide insights into their understanding of genetic issues, and inform public health strategies that promote informed decision-making in reproductive health and genetic counseling.

4) Genetic disorder:
Genetic disorders are conditions caused by abnormalities in genes or chromosomes. These disorders can result from mutations or inherited traits and include various conditions like Down syndrome, thalassemia, and hemophilia. Understanding these disorders is essential for effective management and prevention through genetic testing and counseling.

5) Table:
Tables present data in an organized manner, facilitating the analysis of demographic variables in the study. They display results such as knowledge and attitude scores regarding genetic testing, allowing for easy interpretation of the relationships between various factors, including age, gender, and education, within the research findings.

6) India:
India serves as the geographical setting for the study, where cultural and social factors significantly influence attitudes towards genetic testing. The prevalence of genetic disorders and the practice of consanguineous marriages in India necessitate increased awareness and education about genetic health to reduce the burden of genetic diseases.

7) Birth:
Birth is a critical phase where genetic factors can influence the health and development of a newborn. Genetic testing provides opportunities to detect potential genetic disorders early in pregnancy, thereby informing decisions for prospective parents. Awareness during this stage can lead to improved health outcomes for children and families.

8) Marriage:
Marriages, particularly consanguineous unions, are significant in the context of genetic health. The study aims to raise awareness about the implications of such marriages and their potential to increase genetic disorders in offspring, promoting informed decision-making and education for couples planning to marry.

9) Family:
Family is the primary unit affected by genetic testing and hereditary conditions. Understanding genetic health empowers families to make informed decisions regarding reproductive health and the management of genetic diseases. This knowledge is vital for planning family size and healthcare, and ensuring overall wellbeing.

10) Thalassemia:
Thalassemia is a genetic blood disorder characterized by the insufficient production of hemoglobin, leading to anemia. It is particularly prevalent in India and highlights the importance of genetic screening for at-risk populations, as early diagnosis and management can greatly enhance patient quality of life and reduce complications.

11) Education:
Education refers to the process of imparting knowledge and understanding of genetic issues among newly married couples. It is essential for fostering awareness about genetic testing, potential disorders, and available preventive measures, thus promoting informed health decisions and encouraging healthy reproductive practices.

12) Medicine:
Medicine encompasses the science and art of diagnosing, treating, and preventing diseases, including genetic disorders. Genetic testing is a critical component of modern medicine, allowing for personalized approaches to treatment, disease prevention, and a greater understanding of health risks based on genetic information.

13) Sangli:
Sangli refers to a specific urban area of study within the research, investigating genetic knowledge and attitudes among newly married couples. The socio-cultural dynamics of Sangli, along with demographic trends, play a crucial role in shaping perceptions about genetic health and the importance of informed reproductive decisions.

14) Blood:
Blood is vital for transporting oxygen and nutrients and plays a significant role in genetic disorders related to hematological conditions, such as thalassemia. Understanding blood-related genetic issues is essential for effective diagnosis, management, and prevention of diseases that can affect family health and wellbeing.

15) Developing:
Developing refers to countries or regions working towards improving their economic and social structures. In developing nations like India, the prevalence of genetic disorders is notably higher, emphasizing the need for enhanced education, healthcare resources, and genetic counseling to address public health challenges effectively.

16) Pregnant:
Pregnant women represent a critical demographic for genetic testing and counseling, as detecting genetic disorders early can inform decisions regarding prenatal care and family planning. Awareness among this group can significantly impact health outcomes for both mothers and their future children.

17) Indian:
Indian highlights the cultural and demographic context of the study. Understanding the specific beliefs, traditions, and practices surrounding marriage, family, and healthcare in India is essential for tailoring public health initiatives related to genetic education and testing for populations at risk of genetic disorders.

18) Male:
Male refers to a gender demographic in the study of newly married couples. Understanding the perspectives, knowledge, and attitudes of males towards genetic testing is crucial, as their views can influence family planning decisions and participation in genetic counseling alongside their partners.

19) Life:
Life encapsulates the essence of human experience, which genetic health significantly impacts. Genetic testing and awareness can enhance the quality of life for individuals and communities by providing crucial information about health risks, guiding reproductive choices, and enabling early interventions for genetic conditions.

20) Mutation:
Mutation refers to changes in DNA that can lead to genetic disorders. Understanding the mechanisms of mutations and their inheritance is crucial for assessing the risks of genetic diseases within families, guiding decisions regarding genetic testing and potential interventions for affected individuals.

21) Relative:
Relatives play a vital role in the context of genetic disorders, as understanding familial history can inform genetic counseling and testing decisions. Addressing the connections between relatives helps in assessing risks and creating awareness about the implications of inherited genetic conditions.

22) Bharati:
Bharati refers to Bharati Vidyapeeth Deemed University, where the study was conducted. The institution plays a crucial role in educating future healthcare professionals about genetic health, fostering a knowledgeable generation that can effectively address public health concerns related to genetic testing and counseling.

23) Reason:
Reason highlights the motivations behind the study's focus on genetic testing knowledge and attitudes. Understanding the reasons influencing choices and perceptions related to genetic health can help public health initiatives better address the needs of newly married couples and promote informed reproductive decision-making.

24) Egypt:
Egypt serves as a comparative context for the study, particularly regarding consanguinity and genetic disorders. The prevalence of gene-related diseases in Egypt underscores the global significance of genetic health education and the need for public health strategies tailored to specific cultural and demographic contexts.

25) Miraj:
Miraj is part of the study's geographical focus, representing an urban area where newly married couples' knowledge and attitudes toward genetic testing were assessed. Understanding community characteristics in Miraj is essential for implementing effective health education and genetic counseling programs tailored to local needs.

26) Death:
Death, particularly in relation to genetic disorders and congenital malformations, poses significant public health challenges. Understanding the incidence of death due to genetic conditions can inform preventive health strategies and improve outcomes through early detection and intervention, reducing mortality rates associated with genetic diseases.

27) Pur:
Poor knowledge regarding genetic testing among newly married couples may lead to uninformed reproductive decisions, increasing the risk of genetic disorders in offspring. Addressing poor awareness through targeted education and counseling can significantly impact public health by promoting informed family planning and healthier communities.

28) Discussion:
Discussion is a critical component of the study, facilitating an examination of findings related to knowledge and attitudes toward genetic testing. Engaging in discussions helps to clarify misconceptions, explore societal perceptions, and develop effective strategies to improve genetic health awareness among newly married couples.

29) Science (Scientific):
Science underscores the study's foundation in understanding genetic testing and disorders. It emphasizes the need for scientific literacy in genetics among couples to empower them in making informed health decisions, ultimately contributing to healthier populations and reducing the incidence of genetic disorders.

30) Activity:
Activity refers to the level of engagement and participation in health-related practices among newly married couples. Promoting proactive health-seeking behavior and awareness about genetic testing can enhance their understanding and inform better reproductive choices while navigating familial and societal pressures.

31) Mitra:
Mitra refers to one of the authors of the studies cited, indicating collaboration in the research. The contributions of various researchers underline the importance of shared knowledge and interdisciplinary approaches in addressing genetic health challenges, enhancing the credibility and depth of the study's findings.

32) Gupta:
Gupta is another author associated with the research referenced in the study. Citing multiple experts demonstrates the collaboration necessary for addressing complex health issues such as genetic disorders, ensuring a comprehensive understanding that can lead to informed public health strategies and interventions.

33) Muti (Mutri):
Moodi, mentioned among the authors in the literature, contributes to the collective understanding of genetic health issues addressed in the study. Involving multiple researchers facilitates diverse perspectives and expertise, fostering a more rounded exploration of genetic testing knowledge and attitudes among newly married couples.

Other Science Concepts:

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Discover the significance of concepts within the article: ‘Study on genetic testing knowledge in newlyweds in Sangli Miraj Kupwad.’. Further sources in the context of Science might help you critically compare this page with similair documents:

Genetic disorder, Chronic disease, Negative attitude, Congenital disease, Positive attitude, Sample size, Genetic testing, Prenatal Diagnosis, Correlation analysis, Knowledge and attitude, Demographic variable, Health Care Centre.

Concepts being referred in other categories, contexts and sources.

Newly-married couple, Consanguinity Marriage.

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