A critical review of concept of medha and medhya drugs mentioned in ayurveda

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Journal name: World Journal of Pharmaceutical Research
Original article title: A critical review of concept of medha and medhya drugs mentioned in ayurveda
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Author:

Dr. Megha Gupta and Prof. Mithilesh Verma


World Journal of Pharmaceutical Research:

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Full text available for: A critical review of concept of medha and medhya drugs mentioned in ayurveda

Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research

Doi: 10.20959/wjpr201812-12695

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Summary of article contents:

Introduction

The increasing memory demands on school-age children have led to the emergence of various memory-enhancing drugs. However, many of these pharmaceutical options carry adverse effects, making the use of Ayurvedic alternatives, particularly medhya drugs, more appealing. Ayurvedic literature provides numerous references to medhya drugs aimed at enhancing cognitive functions such as memory and mental agility. This review focuses on the pharmacological properties and mechanisms of action of medhya drugs as highlighted in Ayurveda, offering insights into their therapeutic benefits for improving children's cognitive abilities.

Medha Defined: Components of Intelligence

The term medha in Ayurveda refers to intelligence and encompasses several cognitive aspects: Viveka Shakti (power to discriminate), Grahana Shakti (grasping ability), Dharana Shakti (retention), and Smarana Shakti (recollection). According to different Ayurvedic scholars, medha is analogous to the concept of Dhee, which signifies the retention of knowledge. Various texts define medha in terms of long-lasting, deep knowledge and highlight its significance in enhancing mental capabilities. Understanding these components allows practitioners to appreciate how medhya drugs can stimulate and support these aspects of cognitive function.

The Pharmacological Action of Medhya Drugs

Medhya drugs are known to affect mental processes positively by improving cognitive performance through distinct pharmacological actions. These drugs possess Prabhavajanya effects caused by the proper functioning of Sadhaka Pitta and Tarpaka Kapha, which together maintain the desired cognitive actions. Additionally, medhya drugs exert their influences by alleviating stress and anxiety, thereby nourishing brain function. The mechanism behind their efficacy involves enhanced cerebral metabolism which leads to improved retention power and memory, impacting the functions of Buddhi and Manas in a beneficial manner.

Overview of Prominent Medhya Drugs

Ayurvedic texts enumerate several medhya drugs, each with unique properties and active constituents. For instance, Brahmi (Bacopa monnieri) is recognized for its nootropic effects, attributed to its saponin content, which enhances cognitive functions. Similarly, Guduchi (Tinospora cordifolia) is acknowledged for its neuroprotective qualities, enhancing learning and memory through immunostimulation and cholinergic activity. Other significant medhya drugs include Mandukaparni (Centella asiatica), Shankhapushpi (Convolvulus pluricaulis), and Vacha (Acorus calamus), all demonstrating varying degrees of effectiveness in promoting brain health and cognitive functions according to their distinct constituents and modes of action.

Conclusion

The insights provided through this review illuminate the critical role of medhya drugs in enhancing cognitive performance and memory, especially for children. Ayurvedic formulations offer a holistic approach to improving mental faculties without the adverse effects associated with conventional pharmaceuticals. By selecting appropriate medhya drugs through careful discretion, healthcare practitioners can help foster better intellectual performance and academic success in children. These traditional practices underscore the potential for integrating ancient wisdom into modern therapeutic strategies for cognitive enhancement.

FAQ section (important questions/answers):

What are Medhya drugs in Ayurveda?

Medhya drugs are substances used in Ayurveda to enhance cognitive functions such as memory, comprehension, and retention. They aim to improve mental faculties and are characterized by specific pharmacological properties.

What are the key components of Medha?

Medha comprises four components: Viveka Shakti (discrimination), Grahana Shakti (grasping), Dharaṇa Shakti (retention), and Smaraṇa Shakti (recollection), which together contribute to overall cognitive ability.

What is the significance of Medhya drugs for children?

In the modern scientific era, children face intense memory demands. Medhya drugs help enhance intellectual performance and memory, aiding better academic and social skills.

How do Medhya drugs function in the body?

Medhya drugs improve cerebral metabolism, release stress and anxiety, nourish the brain, and enhance cognitive functions like intellect and memory by correcting disturbances in mental states.

Can you provide examples of common Medhya drugs?

Examples include Mandukaparni, Yastimadhu, Shankhapushpi, and Brahmi, each known for their unique properties and benefits in enhancing cognitive functions.

What role do chemical constituents play in Medhya drugs?

The chemical constituents of Medhya drugs like bacosides in Brahmi and glycyrrhizic acid in Yastimadhu contribute to their neuroprotective and cognitive-enhancing effects, supporting memory and learning.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “A critical review of concept of medha and medhya drugs mentioned in ayurveda”. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Drug:
In Ayurveda, the term 'drug' refers to substances used for therapeutic purposes to treat various ailments. In the context of Medhya drugs, these are specifically aimed at enhancing cognitive functions such as memory and intelligence. The focus is on natural components that have beneficial effects on mental health and cognitive performance.

2) Medhya:
Medhya refers to a classification of Ayurvedic drugs that are specifically designed to enhance mental faculties, including memory, understanding, and retention. These drugs aim to improve cognitive abilities in individuals, especially children, ensuring better academic performance and mental agility. They are pivotal in the Ayurvedic system for maintaining mental health.

3) Medha (Medhas):
Medha is the Sanskrit word for intelligence or cognitive ability, embodying aspects such as comprehension, retention, and recollection. In Ayurveda, it is linked to the mental prowess and is fundamental to the characteristics of an individual. Enhancing Medha is considered essential for optimal learning and intellectual growth.

4) Learning:
Learning, within the context of Ayurveda, pertains to the process of acquiring knowledge or skills. It is fundamentally linked to mental functions that are enhanced by Medhya drugs. Effective learning is crucial for children to develop socially and academically, ensuring their overall well-being and cognitive development.

5) Tikta:
Tikta translates to 'bitter' in Sanskrit and describes one of the tastes (Rasa) in Ayurveda. Many Ayurvedic medicinals possess this quality and are believed to facilitate various therapeutic functions, particularly detoxification and cleansing in the body, contributing to improved physical and mental health.

6) Megha:
Megha Gupta is the lead author of the reviewed article discussing Medhya drugs in Ayurveda. Her contributions pertain to the exploration of Ayurvedic medicinal practices and their implications for cognitive enhancement. The research underscores the importance of integrating traditional knowledge with modern science in addressing educational challenges.

7) Ayurveda (Ayus-veda):
Ayurveda is a holistic system of medicine that originated in ancient India, focusing on balancing the body, mind, and spirit. It employs a variety of natural treatments, including herbs and dietary practices, to promote health, prevent disease, and improve mental clarity and overall well-being.

8) Katu:
Katu denotes a 'pungent' taste in Ayurveda. It is one of the six tastes and influences different physiological and therapeutic functions in the body. Katu drugs may stimulate digestion and circulation, thereby supporting mental health and cognitive functions by balancing the body's doshas.

9) Withania somnifera:
Withania somnifera, commonly known as Ashwagandha, is an adaptogenic herb celebrated in Ayurveda for its neuroprotective and rejuvenating properties. It enhances memory, reduces stress, and has been found effective in preventing cognitive decline, making it crucial in therapeutic interventions for mental health.

10) Activity:
Activity in the context of Medhya drugs refers to their pharmacological effects and mechanisms that enhance mental functions. This includes various biological impacts such as neuroprotective effects, memory retention, and cognitive improvements attributed to the active compounds present in these drugs.

11) Snigdha:
Snigdha means 'unctuous or oily,' indicating the property of drugs that possess moisturizing or nourishing qualities. In Ayurvedic practice, Snigdha substances are thought to enhance overall health and vitality, which can indirectly support cognitive processes and mental agility.

12) Laghu:
Laghu translates to 'light' in Sanskrit and describes the property of certain drugs. In Ayurveda, Laghu substances are easier to digest and assimilate, enhancing their effectiveness. Such properties are particularly important in formulating medicines aimed at improving mental clarity and agility.

13) Shankhapushpi (Sankhapuspi, Samkhapuspi):
Shankhapushpi is an important Ayurvedic herb known for its cognitive enhancing properties. Used extensively for its Medhya effects, it is believed to improve memory and intellect while relieving anxiety and stress, thereby supporting better mental health and learning capacities.

14) Performance:
Performance relates to the effectiveness with which an individual can employ cognitive skills and knowledge. Ayurvedic Medhya drugs aim to enhance this performance, especially among school-age children, thus playing a crucial role in educational achievement and mental proficiency.

15) Buddhi:
Buddhi refers to intellect or wisdom in Sanskrit and is a core concept in Ayurveda that embodies mental faculties. It signifies the deeper understanding and retention of knowledge, and enhancing Buddhi is essential for effective learning and overall cognitive development.

16) Shakti (Sakti):
Shakti translates to 'power' or 'capability' in Sanskrit. In the context of cognition, it represents the strength of mental faculties such as memory and comprehension, which are critical elements influenced by Medhya drugs and Ayurveda in general.

17) Vaca:
Vacha, or Acorus calamus, is an Ayurvedic herb with properties that enhance cognition and mental clarity. Its use in traditional medicine highlights its effectiveness in improving memory retention and relieving conditions associated with confusion and distraction.

18) Sita (Shita):
Shita means 'cold' and indicates substances with a cooling property in Ayurveda. These qualities are significant for creating balance in bodily functions and can enhance mental clarity and calm, essential for cognitive performance.

19) Ushna (Usna):
Ushna means 'hot' and refers to substances that can elevate body temperature and stimulate bodily functions. Ushna drugs can be beneficial, enhancing cognitive performance depending on individual constitutional needs.

20) Tinospora cordifolia:
Tinospora cordifolia, also known as Guduchi, is an Ayurvedic herb revered for its immunomodulating and neuroprotective effects. It supports cognitive functions, enhances memory, and exhibits antioxidant properties, helping to maintain mental agility and health.

21) Mental health:
Mental health refers to the emotional, psychological, and social well-being of individuals. It encompasses how one thinks, feels, and behaves. In Ayurveda, maintaining mental health is crucial for overall well-being, and Medhya drugs play a vital role in supporting cognitive and emotional resilience.

22) Yashtimadhu (Yastimadhu, Yashti-madhu):
Yastimadhu, also known as Glycyrrhiza glabra, plays a significant role in Ayurveda for its various health benefits. It is recognized for its ability to improve cognitive functions, reduce anxiety, and modulate stress responses, aiding in better mental clarity and overall health.

23) Bhasma (Bhasman):
Bhasma refers to calcined ash of metals or minerals used in Ayurvedic formulations to enhance medicinal properties. It is believed that the process of calcination improves bioavailability and efficacy, contributing to the overall therapeutic effects of Ayurvedic medicines, particularly in mental health.

24) Ghrita (Ghrta):
Ghrita, or ghee, is clarified butter used in Ayurveda as a carrier for medicinal herbs. It enhances the absorption of active compounds in Medhya drugs, thus playing a crucial role in cognitive development and overall health by nourishing the brain and supporting mental functions.

25) Madhu:
Madhu means 'honey' in Sanskrit and is often used in Ayurvedic formulations for its sweet taste and nourishing qualities. It serves as a natural sweetener and is believed to enhance the efficacy of medications, particularly those used for mental and cognitive enhancement.

26) Kaumarabhritya (Kaumarabhrtya, Kaumara-bhritya):
Kaumarabhritya is a branch of Ayurveda that focuses on the health and development of children. This specialty emphasizes the importance of mental and physical wellness in early development, promoting the use of Medhya drugs for enhancing cognitive abilities in youth.

27) Acorus calamus:
Acorus calamus, also known as Vacha, is an Ayurvedic herb recognized for its cognitive benefits. It has been traditionally used to enhance memory, increase mental clarity, and treat various psychological issues, thereby holding a significant place in Ayurvedic practices aimed at improving cognitive function.

28) Mandukaparni (Manduka-parni, Mamdukaparni):
Mandukaparni, or Centella asiatica, is an herb known for its ability to enhance cognitive functions, particularly memory and learning. Its active compounds contribute to improved mental performance and neuroprotective effects, making it a vital ingredient in Medhya formulations.

29) Jyotishmati (Jyotismati, Jyotirmati):
Jyotishmati, or Celastrus panniculata, is a revered herb in Ayurveda used for its cognitive-enhancing properties. It is believed to improve memory function and alleviate cognitive deficits, supporting mental well-being through traditional herbal practices.

30) Samhita:
Samhitas are ancient texts in Ayurveda that compile knowledge on medicinal herbs and practices. They provide foundational information essential for understanding the use and benefits of Medhya drugs in enhancing cognitive abilities.

31) Dharana:
Dharana translates to 'retention' in Sanskrit, representing an important aspect of memory in Ayurveda. It refers to the ability to hold and recall information, which is critical for learning and intellectual growth, especially in the context of children’s education.

32) Lucknow:
Lucknow is a city in India known for its historical significance and educational institutions. It is also home to several Ayurvedic colleges and practitioners, fostering research and development in traditional medicine, including the study of Medhya drugs for cognitive enhancement.

33) Disease:
Diseases are pathological conditions that impair normal bodily functions. In Ayurveda, numerous herbs and treatments are designed to address such diseases, particularly those associated with cognitive impairments and mental health issues through the use of Medhya drugs.

34) Brahmi:
Brahmi, or Bacopa monnieri, is an Ayurvedic herb celebrated for its cognitive enhancement properties. Known for its ability to improve memory, reduce anxiety, and increase learning ability, Brahmi is a key ingredient in numerous Medhya formulations that support mental health.

35) Animal:
Animals serve as subjects in studies assessing the efficacy of Ayurvedic drugs, including Medhya drugs. Research involving animals provides insight into the cognitive benefits of these herbs, validating their use for enhancing memory and mental health.

36) Virya:
Virya denotes the potency or energy of a substance in Ayurveda, influencing its therapeutic effects. Different Virya qualities, such as Ushna (hot) and Shita (cold), play significant roles in determining how a drug will interact with the body's doshas and its effectiveness in treating mental health issues.

37) Glycirrhiza glabra:
Glycyrrhiza glabra, known as Yashtimadhu or liquorice, is an herb noted for its sweet flavor and wide-ranging therapeutic uses. In Ayurveda, it is valued for enhancing cognitive ability, providing anti-inflammatory benefits, and supporting brain health, making it essential for mental wellness.

38) Pharmacological:
Pharmacological refers to the study of how drugs affect biological systems, including their mechanisms, effects, and therapeutic uses. Understanding the pharmacological properties of Medhya drugs aids in their effective application in treating cognitive disorders and enhancing memory.

39) Ashvagandha (Asvagandha, Ashwagandha, Ashvagamdha, Ashva-gandha):
Ashwagandha, or Withania somnifera, is an adaptogenic herb acclaimed for its cognitive benefits. It supports stress management, enhances memory, and possesses antioxidant properties, making it a key component in Ayurvedic medicine aimed at improving brain function and overall mental health.

40) Knowledge:
Knowledge in Ayurveda encompasses the understanding of medicinal plants, their uses, and the principles of health. It is essential for practitioners in selecting appropriate treatments, especially when dealing with cognitive enhancement and the application of Medhya drugs for memory improvement.

41) Kashyapa (Kasyapa, Kashya-pa, Kashyapanamdana):
Kashyapa, an ancient sage in Ayurveda, is often cited in texts related to medicinal practices and herbal treatments. His teachings contribute to the understanding and application of cognitive-enhancing properties of various herbs mentioned in Ayurvedic literature.

42) Medicine:
Medicine refers to substances used to treat illnesses or enhance health. In Ayurveda, medicines often involve natural herbs and formulations designed to improve mental functions, such as Medhya drugs that enhance learning and memory capacities.

43) Bhavana (Bha-vana):
Bhavana in Ayurveda denotes the process of potentiating medicinal herbs through techniques such as grinding and preparing with specific liquids. This enhances the efficacy of drugs, including those aimed at cognitive enhancement, by aiding in the absorption of active compounds.

44) Grahana:
Grahana refers to the act of grasping, understanding, or apprehending knowledge. It is a key component of cognitive functions important in learning processes. Medhya drugs aim to bolster Grahana by enhancing comprehension and retention abilities.

45) Tikshna (Tiksna):
Tikshna means 'sharp' or 'pungent' in Sanskrit and indicates a quality that enhances the effectiveness of certain Ayurvedic drugs. Substances with Tikshna properties can stimulate digestive fires and cognitive functions, therefore contributing positively to mental performance.

46) Anxiety:
Anxiety is a state of mental unease or worry that can affect cognitive abilities and overall health. Ayurvedic approaches, including the use of Medhya drugs, focus on alleviating anxiety to promote better mental function and emotional stability.

47) Smriti (Smrti):
Smriti translates to 'memory' in Sanskrit. In the context of Ayurveda, it is regarded as a critical component of mental faculties. Enhancing Smriti is essential for learning, and Medhya drugs are specifically formulated to support this cognitive skill.

48) Vipaka:
Vipaka refers to the post-digestive effect of a substance in Ayurveda, determining its final influence on the body after digestion. This quality is crucial in understanding how Medhya drugs will interact with the body and support cognitive health.

49) Kashaya (Kasaya):
Kasaya means 'astringent' and is one of the tastes recognized in Ayurveda. Astringent drugs are useful in various treatments, including those aimed at mental health, where they help in healing and balancing bodily functions critical for cognitive clarity.

50) Pitta:
Pitta is one of the three doshas in Ayurveda, representing fire and transformation in the body. An imbalance in Pitta can lead to mental disturbances and cognitive issues. Remedies that balance Pitta are essential for enhancing memory and cognitive functions.

51) Kapha:
Kapha is another dosha in Ayurveda, signifying stability and structure. While it provides grounding, an imbalance can lead to lethargy and mental fog. Understanding Kapha is crucial for applying appropriate Medhya drugs that enhance cognitive performance while balancing this dosha.

52) Bhava:
Bhava translates to 'mood' or 'state of being' in Ayurveda. It encompasses emotional and mental well-being. The study and understanding of Bhava are essential for applying Medhya drugs effectively to support mental health and optimal cognitive functions.

53) Gupta:
Gupta denotes 'protected' or 'hidden' and is a common surname in India. In the context of this article, it refers to Dr. Megha Gupta, a key contributor to Ayurvedic research on Medhya drugs and cognitive enhancement, lending her expertise to the field.

54) Water:
Water is a universal solvent and fundamental for life. In Ayurveda, it is often used in the preparation of herbal medicines and, through processes like Bhavana, enhances the efficacy of herbs, including those targeting cognitive enhancement.

55) Study (Studying):
Study refers to the systematic examination or research conducted to understand a topic. In the context of Ayurveda, studies help validate the efficacy of Medhya drugs on cognitive functions, providing scientific backing to traditional claims regarding memory enhancement.

56) Guru:
Guru translates to 'teacher' or 'mentor' in Sanskrit. In Ayurveda, the role of a Guru is vital in imparting knowledge regarding medicinal practices and formulations, including the use of Medhya drugs for cognitive enhancement and mental health.

57) Rasa (Rasha):
Rasa refers to the taste of substances in Ayurveda and plays a crucial role in determining their therapeutic properties. Understanding Rasa is essential for crafting formulations, particularly Medhya drugs, aimed at improving cognitive abilities and overall health.

58) Leha:
Leha denotes semi-solid forms of Ayurvedic preparations, often used as dietary supplements or therapeutic agents. Such formulations can be rich in Medhya properties, supporting cognitive health and enhancing learning capacities through their nutritional benefits.

59) Nardostachys jatamansi (Nardostachys jatamamsi):
Nardostachys jatamamsi, known as Jatamansi, is an Ayurvedic herb recognized for its calming effects on the mind. It is utilized for its potential to enhance memory and alleviate stress, making it an important component in formulations aimed at improving cognitive function.

60) Glycyrrhiza glabra:
Glycyrrhiza glabra, or Yashtimadhu, is an Ayurvedic herb celebrated for its ability to support cognitive functions. It is used to enhance memory, reduce anxiety, and improve overall mental clarity, making it essential for maintaining mental health.

61) Mental disorder:
Mental disorder describes health conditions characterized by changes in emotions, thinking, and behavior, impacting daily functioning. Ayurvedic treatments, particularly those involving Medhya drugs, focus on restoring mental balance and enhancing cognitive capabilities.

62) Sushruta-samhita (Susruta-samhita):
Sushruta-samhita refers to one of the foundational texts of Ayurveda that outlines surgical techniques and medicinal practices. This text contributes to the understanding of Medhya drugs and their applications in enhancing cognitive functions and mental health.

63) Kashyapasamhita (Kasyapasamhita, Kashyapa-samhita):
Kashyapa-samhita is an ancient Ayurvedic text attributed to Sage Kashyapa, detailing child health practices. It includes essential knowledge on Medhya drugs for enhancing children's cognitive abilities, reflecting the importance of mental health in early development.

64) Kalyanakaghrita (Kalyanakaghrta, Kalyanaka-ghrita):
Kalyanakaghrita is an Ayurvedic preparation that combines ghee with beneficial herbs. It is recognized for its nourishing properties and is often used in formulations aimed at enhancing cognitive functions and overall mental well-being.

65) Manasikabhava (Manasika-bhava):
Manasika-bhava refers to the mental state or disposition in Ayurveda. Understanding this concept is crucial for applying Medhya drugs effectively, as they aim to enhance cognitive performance and emotional stability by positively influencing Manasika-bhava.

66) Sadhakapitta (Sadhaka-pitta):
Sadhaka-pitta is a sub-dosha responsible for emotional and mental functions in Ayurveda. It plays a significant role in cognition, and maintaining its balance is crucial for supporting memory and intellectual abilities through the use of Medhya drugs.

67) Tarpakakapha (Tarpaka-kapha):
Tarpaka-kapha is a sub-dosha responsible for nourishing the nervous system and supporting mental functions. Its balance is essential for cognitive health, and Medhya drugs play a vital role in enhancing Tarpaka-kapha to improve mental clarity and memory.

68) Brahmighrita (Brahmighrta, Brahmi-ghrita):
Brahmighrita is a specific Ayurvedic formulation combining ghee and the Brahmi herb. This preparation is renowned for its cognitive-enhancing effects, aiming to improve memory and mental endurance, making it significant for students and individuals focused on learning.

69) Inflammation:
Inflammation is the body’s response to injury or infection, often marking conditions affecting mental and physical health negatively. Ayurvedic treatments, including Medhya drugs, often target inflammation to improve cognitive functions and overall well-being.

70) Arunadatta:
Arunadatta is mentioned as an authority in Ayurveda, contributing to the understanding of medicinal properties and treatments. His insights enhance the knowledge regarding Medhya drugs and their effects on cognitive functions in Ayurvedic practices.

71) Arkapushpi (Arkapuspi, Arka-pushpi):
Arkapushpi is an Ayurvedic herb noted for its potential benefits on mental health. It is documented for enhancing cognitive functions and is used in various formulations targeting mind-related ailments.

72) Anti-aging:
Anti-aging in Ayurveda pertains to practices and therapies that improve longevity and vitality. Medhya drugs are often included in anti-aging protocols for their neuroprotective qualities, enhancing cognitive function and mental health as one ages.

73) Science (Scientific):
Scientific refers to a methodical approach to studying phenomena through observation and experimentation. The scientific examination of Ayurveda, particularly the efficacy of Medhya drugs for cognitive enhancement, provides validation and supports traditional claims concerning mental health.

74) Ratnakara (Ratna-akara, Ratna-kara):
Ratnakara is one of the ancient Ayurvedic texts that compile valuable medicinal knowledge and practices. It is significant for understanding the applications of Medhya drugs in enhancing cognitive capabilities and maintaining mental health.

75) Mastishka (Mastiska):
Mastishka translates to 'brain' in Sanskrit, signifying its importance in Ayurvedic practice. Medhya drugs are aimed at nourishing Mastishka to enhance cognitive functions, memory, and overall mental performance.

[Note: The above list is limited to 75. Total glossary definitions available: 113]

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